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J. Setton · SciRah

Researcher profile · Semantic Scholar

J. Setton

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J. Setton — researcher profile on SciRah

h-index: 27
Works: 111
Citations: 2,331

Most-cited papers

Distinct classes of complex structural variation uncovered across thousands of cancer genome graphs
Kevin Hadi, Xiao-Tong Yao, Julie M. Behr, Aditya Deshpande +48 more
2020Cell217 citations Open access
Semantic Scholar
Mutations in BRCA1 and BRCA2 differentially affect the tumor microenvironment and response to checkpoint blockade immunotherapy
R. Samstein, C. Krishna, Xiao-Xiao Ma, X. Pei +24 more
2020Nature Cancer189 citations Open access
Semantic Scholar
The therapeutic significance of mutational signatures from DNA repair deficiency in cancer
Jennifer Ma, J. Setton, N. Y. Lee, N. Riaz +1 more
2018Nature Communications173 citations Open access
Semantic Scholar
Intensity-modulated radiotherapy in the treatment of oropharyngeal cancer: an update of the Memorial Sloan-Kettering Cancer Center experience.
J. Setton, N. Caria, J. Romanyshyn, L. Koutcher +15 more
2012International Journal of Radiation Oncology, Biology, Physics172 citations
Semantic Scholar
18F-FDG PET/CT Metabolic Tumor Volume and Total Lesion Glycolysis Predict Outcome in Oropharyngeal Squamous Cell Carcinoma
Remy C. Lim, A. Eaton, N. Lee, J. Setton +5 more
2012Journal of Nuclear Medicine170 citations Open access
Semantic Scholar
Synthetic Lethality in Cancer Therapeutics: The Next Generation
J. Setton, M. Zinda, N. Riaz, D. Durocher +4 more
2021Cancer Discovery164 citations Open access
Semantic Scholar
A Multi-Institution Pooled Analysis of G-Tube Dependence in Patients with Oropharyngeal Cancer Treated with Definitive IMRT
J. Setton, N. Lee, N. Riaz, Shao H. Huang +7 more
2014Cancer126 citations Open access
Semantic Scholar
INTENSITY-MODULATED RADIATION THERAPY IN OROPHARYNGEAL CARCINOMA: EFFECT OF TUMOR VOLUME ON CLINICAL OUTCOMES
B. Lok, J. Setton, N. Caria, J. Romanyshyn +16 more
2011International Journal of Radiation Oncology, Biology, Physics74 citations Open access
Semantic Scholar
Characteristics and Outcomes of Sentinel Node–Positive Breast Cancer Patients after Total Mastectomy without Axillary-Specific Treatment
S. Milgrom, H. Cody, Tan K. Lee, M. Morrow +9 more
2012Annals of Surgical Oncology66 citations
Semantic Scholar
Pathogenic ATM Mutations in Cancer and a Genetic Basis for Radiotherapeutic Efficacy.
K. Pitter, D. Casey, Yue Lu, M. Hannum +27 more
2020Journal of the National Cancer Institute64 citations Open access
Semantic Scholar
Predictive modeling of outcomes following definitive chemoradiotherapy for oropharyngeal cancer based on FDG-PET image characteristics
M. Folkert, J. Setton, A. Apte, M. Grkovski +6 more
2017Physics in Medicine and Biology61 citations Open access
Semantic Scholar
Percutaneous Endoscopic Gastrostomy in Oropharyngeal Cancer Patients Treated With Intensity-Modulated Radiotherapy With Concurrent Chemotherapy
P. Romesser, J. Romanyshyn, K. Schupak, J. Setton +6 more
2012Cancer55 citations Open access
Semantic Scholar
Long-term patterns of relapse and survival following definitive intensity-modulated radiotherapy for non-endemic nasopharyngeal carcinoma
J. Setton, James E Han, D. Kannarunimit, Y. Wuu +7 more
2015Oral Oncology53 citations Open access
Semantic Scholar
Efficacy of concurrent cetuximab vs. 5-fluorouracil/carboplatin or high-dose cisplatin with intensity-modulated radiation therapy (IMRT) for locally-advanced head and neck cancer (LAHNSCC)
Lauren Q. Shapiro, E. Sherman, N. Riaz, J. Setton +8 more
2014Oral Oncology52 citations Open access
Semantic Scholar
Dose-volume factors correlating with trismus following chemoradiation for head and neck cancer
Shyam Rao, Z. Saleh, J. Setton, M. Tam +4 more
2015Acta oncologica48 citations Open access
Semantic Scholar
Definitive treatment of metastatic nasopharyngeal carcinoma: Report of 5 cases with review of literature
J. Setton, S. Wolden, N. Caria, N. Lee
2012Head and Neck44 citations
Semantic Scholar
Most large structural variants in cancer genomes can be detected without long reads
Zi-Ning Choo, Julie M. Behr, Aditya Deshpande, Kevin Hadi +16 more
2023Nature Genetics42 citations Open access
Semantic Scholar
Estimate of the impact of FDG-avidity on the dose required for head and neck radiotherapy local control
Jeho Jeong, J. Setton, N. Lee, J. Oh +1 more
2014Radiotherapy and Oncology41 citations Open access
Semantic Scholar
Long-molecule scars of backup DNA repair in BRCA1- and BRCA2-deficient cancers
J. Setton, Kevin Hadi, Zi-Ning Choo, Katherine S Kuchin +17 more
2023Nature40 citations Open access
Semantic Scholar
Long-Term Regional Control in the Observed Neck Following Definitive Chemoradiation for Node-Positive Oropharyngeal Squamous Cell Cancer
A. Goenka, L. Morris, Shyam S. D. Rao, S. Wolden +13 more
2013International Journal of Cancer38 citations Open access
Semantic Scholar
The relative prognostic utility of standardized uptake value, gross tumor volume, and metabolic tumor volume in oropharyngeal cancer patients treated with platinum based concurrent chemoradiation with a pre-treatment [18F] fluorodeoxyglucose positron emission tomography scan
P. Romesser, Remy C. Lim, D. Spratt, J. Setton +6 more
2014Oral Oncology37 citations Open access
Semantic Scholar
Genomic analysis of exceptional responders to radiotherapy reveals somatic mutations in ATM
Jennifer Ma, J. Setton, L. Morris, Pedro Blecua Carrillo Albornoz +10 more
2016OncoTarget35 citations Open access
Semantic Scholar
The Landscape of Somatic Genetic Alterations in Breast Cancers from CHEK2 Germline Mutation Carriers
D. Mandelker, Rahul Kumar, X. Pei, P. Selenica +11 more
2019JNCI Cancer Spectrum34 citations Open access
Semantic Scholar
A radiomics model from joint FDG-PET and MRI texture features for the prediction of lung metastases in soft-tissue sarcomas of the extremities
Zhiguo Zhou, M. Folkert, P. Iyengar, J. Setton +2 more
201529 citations
Semantic Scholar
Radiation field design and regional control in sentinel lymph node‐positive breast cancer patients with omission of axillary dissection
J. Setton, H. Cody, Tan K. Lee, M. Morrow +5 more
2012Cancer29 citations Open access
Semantic Scholar
Germline RAD51B variants confer susceptibility to breast and ovarian cancers deficient in homologous recombination
J. Setton, P. Selenica, S. Mukherjee, Rachna Shah +17 more
2021npj Breast Cancer27 citations Open access
Semantic Scholar
Time course and predictors for cancer-related fatigue in a series of oropharyngeal cancer patients treated with chemoradiation therapy.
D. Spratt, Mayuko Sakae, N. Riaz, B. Lok +6 more
2012The Oncologist27 citations Open access
Semantic Scholar
Homologous recombination deficiency: how genomic signatures are generated
J. Setton, J. Reis-Filho, S. Powell
2021Current Opinion in Genetics and Development25 citations Open access
Semantic Scholar
Patterns of nodal failure after intensity modulated radiotherapy for nasopharyngeal carcinoma
Jin-Gao Li, P. Venigalla, J. Leeman, Q. LaPlant +6 more
2017The Laryngoscope22 citations
Semantic Scholar
Modeling Dose Response for Late Dysphagia in Patients With Head and Neck Cancer in the Modern Era of Definitive Chemoradiation.
C. Tsai, A. Jackson, J. Setton, N. Riaz +5 more
2017JCO Clinical Cancer Informatics22 citations Open access
Semantic Scholar
Patients with low lying lymph nodes are at high risk for distant metastasis in oropharyngeal cancer.
N. Riaz, J. Setton, M. Tam, E. Sherman +6 more
2014Oral Oncology21 citations Open access
Semantic Scholar
18 F-FDG PET / CT Metabolic Tumor Volume and Total Lesion Glycolysis Predict Outcome in Oropharyngeal Squamous Cell Carcinoma
Remy C. Lim, A. Eaton, N. Lee, J. Setton +4 more
201215 citations
Semantic Scholar
Novel patterns of complex structural variation revealed across thousands of cancer genome graphs
Kevin Hadi, Xiao-Tong Yao, Julie M. Behr, Aditya Deshpande +44 more
2019bioRxiv13 citations Open access
Semantic Scholar
The cold immunological landscape of ATM-deficient cancers
Sonali Sinha, V. Ng, Ardijana Novaj, Yin Zhu +21 more
2025Journal for ImmunoTherapy of Cancer9 citations Open access
Semantic Scholar
ATM Germline-Mutated Gastroesophageal Junction Adenocarcinomas: Clinical Descriptors, Molecular Characteristics, and Potential Therapeutic Implications
Tony El Jabbour, M. Misyura, Darren Cowzer, M. Zimmermann +18 more
2022Journal of the National Cancer Institute8 citations Open access
Semantic Scholar
Constraining the brachial plexus does not compromise regional control in oropharyngeal carcinoma
M. W. Robert, B. Lok, P. Dutta, N. Riaz +7 more
2011Radiation Oncology8 citations Open access
Semantic Scholar
Genotype-directed synthetic cytotoxicity of ATR inhibition with radiotherapy
V. Ng, Sonali Sinha, Ardijana Novaj, Jennifer Ma +17 more
2024Clinical Cancer Research7 citations
Semantic Scholar
Pathogenic Mutations in ATM As Determinants of Local Control in Non-Small Cell Lung Cancers Treated with Radiation Therapy
K. Pitter, D. Casey, J. Setton, C. Lu +6 more
2018International Journal of Radiation Oncology, Biology, Physics5 citations Open access
Semantic Scholar
A Multi-institution Pooled Analysis of G-Tube Dependence in Patients With Oropharyngeal Cancer Treated With Definitive IMRT
J. Setton, N. Lee, S.-H. Huang, J. Waldron +6 more
20135 citations Open access
Semantic Scholar
AlphaMissense for Identifying Pathogenic Missense Mutations in DNA Damage Repair Genes in Cancer
S. Yazaki, Xin Pei, S. Powell, Atif J. Khan +2 more
2025JCO Precision Oncology4 citations Open access
Semantic Scholar
Large-scale copy number alterations are enriched for synthetic viability in BRCA1/BRCA2 tumors
Ying-Jie Zhu, Xin Pei, Ardijana Novaj, J. Setton +17 more
2024Genome Medicine4 citations Open access
Semantic Scholar
Prospective Dysphagia Quality of Life Scores and Treatment Outcomes in Oropharyngeal Cancer Patients: Is it Time to Reconsider the Prophylactic Percutaneous Endoscopic Gastrostomy?
P. Romesser, M. Tam, Zuo-Feng Zhang, J. Setton +5 more
20134 citations Open access
Semantic Scholar
Impact of Clonal Hematopoiesis on Solid Tumor Progression Following Radiation Therapy
Jacqueline J. Tao, J. Setton, Pablo Sánchez Vela, A. Safonov +9 more
2025JCO Precision Oncology3 citations
Semantic Scholar
Increased Synthetic Cytotoxicity of Combinatorial Chemoradiation Therapy in Homologous Recombination Deficient Tumors
Jennifer Ma, Rachna Shah, Andrew C. Bell, Niamh McDermott +12 more
2024International Journal of Radiation Oncology, Biology, Physics3 citations Open access
Semantic Scholar
CDK12 loss leads to replication stress and sensitivity to combinations of the ATR inhibitor camonsertib (RP-3500) with PARP inhibitors
J. Setton, D. Gallo, D. Głodzik, B. Kaiser +10 more
2022European Journal of Cancer3 citations Open access
Semantic Scholar
DNA double-strand repair by nonhomologous end joining and its clinical relevance
J. Setton, R. Bindra, S. Powell
20163 citations
Semantic Scholar
A Multi-institution Pooled Analysis of G-Tube Dependence in Patients With Oropharyngeal Cancer Treated With Definitive IMRT: Definitive Management of Head-and-Neck Squamous Cell Carcinoma
J. Setton, N. Lee, S.-H. Huang, J. Waldron +6 more
20143 citations Open access
Semantic Scholar
Efficacy of concurrent cetuximab (C225) versus 5-fluorouracil/carboplatin (5FU/CBDCA) or cisplatin (CDDP) with intensity-modulated radiation therapy (IMRT) for locally advanced head and neck cancer (LAHNSCC).
Lauren Q. Shapiro, E. Sherman, L. Koutcher, J. Setton +8 more
20123 citations
Semantic Scholar
Lesion Glycolysis Predict Outcome in Oropharyngeal Squamous Cell Carcinoma
Remy C. Lim, A. Eaton, N. Lee, J. Setton +5 more
20123 citations
Semantic Scholar
Moving beyond PARP Inhibition in ATM-Deficient Prostate Cancer
J. Setton, S. Powell
2020Cancer Research2 citations
Semantic Scholar

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