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Wayland W. L. Cheng · SciRah

Researcher profile · Semantic Scholar

Wayland W. L. Cheng

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Wayland W. L. Cheng — researcher profile on SciRah

h-index: 16
Works: 39
Citations: 720

Most-cited papers

Mechanism for selectivity-inactivation coupling in KcsA potassium channels
Wayland W. L. Cheng, J. Mccoy, A. Thompson, C. Nichols +1 more
2011Proceedings of the National Academy of Sciences of the United States of America90 citations Open access
Semantic Scholar
Dual-mode phospholipid regulation of human inward rectifying potassium channels.
Wayland W. L. Cheng, Nazzareno D’Avanzo, D. Doyle, C. Nichols
2011Biophysical Journal71 citations Open access
Semantic Scholar
Direct and Specific Activation of Human Inward Rectifier K+ Channels by Membrane Phosphatidylinositol 4,5-Bisphosphate*
Nazzareno D’Avanzo, Wayland W. L. Cheng, D. Doyle, C. Nichols
2010Journal of Biological Chemistry71 citations Open access
Semantic Scholar
Photoaffinity labeling with cholesterol analogues precisely maps a cholesterol-binding site in voltage-dependent anion channel-1
Melissa M. Budelier, Wayland W. L. Cheng, L. Bergdoll, Zi-Wei Chen +7 more
2017Journal of Biological Chemistry64 citations Open access
Semantic Scholar
Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1
P. Schmidpeter, John T. Ii Petroff, Leila Khajoueinejad, Aboubacar Wague +4 more
2023Nature Communications62 citations Open access
Semantic Scholar
KirBac1.1: It's an Inward Rectifying Potassium Channel
Wayland W. L. Cheng, D. Enkvetchakul, C. Nichols
2009The Journal of General Physiology62 citations Open access
Semantic Scholar
The Role of the Cytoplasmic Pore in Inward Rectification of Kir2.1 Channels
H. Kurata, Wayland W. L. Cheng, C. Arrabit, P. Slesinger +1 more
2007The Journal of General Physiology43 citations Open access
Semantic Scholar
Energetics and Location of Phosphoinositide Binding in Human Kir2.1 Channels*
Nazzareno D’Avanzo, Sun-Joo Lee, Wayland W. L. Cheng, C. Nichols
2013Journal of Biological Chemistry36 citations Open access
Semantic Scholar
Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation
John T. Petroff, Noah M. Dietzen, Ezry Santiago-McRae, Brett Deng +11 more
2022Nature Communications31 citations Open access
Semantic Scholar
Mapping two neurosteroid-modulatory sites in the prototypic pentameric ligand-gated ion channel GLIC
Wayland W. L. Cheng, Zi-Wei Chen, John R. Bracamontes, Melissa M. Budelier +7 more
2018Journal of Biological Chemistry27 citations Open access
Semantic Scholar
Functional Complementation and Genetic Deletion Studies of KirBac Channels
J. Paynter, I. Andres-Enguix, P. Fowler, S. Tottey +8 more
2010Journal of Biological Chemistry26 citations Open access
Semantic Scholar
Expression and purification of recombinant human inward rectifier K+ (KCNJ) channels in Saccharomyces cerevisiae
Nazzareno D’Avanzo, Wayland W. L. Cheng, X. Xia, Liang Dong +3 more
2010Protein Expression and Purification24 citations Open access
Semantic Scholar
Druggable Lipid Binding Sites in Pentameric Ligand-Gated Ion Channels and Transient Receptor Potential Channels
Wayland W. L. Cheng, Mark J. Arcario, John T. Petroff
2022Frontiers in Physiology22 citations Open access
Semantic Scholar
Random assembly of SUR subunits in KATP channel complexes
Wayland W. L. Cheng, Ailing Tong, Thomas P. Flagg, C. Nichols
2008Channels21 citations Open access
Semantic Scholar
Lipids driving protein structure?
Nazzareno D’Avanzo, Wayland W. L. Cheng, Shi-Zhen Wang, D. Enkvetchakul +1 more
2010Channels19 citations Open access
Semantic Scholar
Numerical fluorescence correlation spectroscopy for the analysis of molecular dynamics under nonstandard conditions.
Michael J. Culbertson, Joshua T. b. Williams, Wayland W. L. Cheng, Dee Ann Stults +3 more
2007Analytical Chemistry18 citations
Semantic Scholar
Polyunsaturated fatty acids inhibit a pentameric ligand-gated ion channel through one of two binding sites
Noah M. Dietzen, Mark J. Arcario, Lawrence J. Chen, John T. Petroff +5 more
2021bioRxiv12 citations Open access
Semantic Scholar
Mechanically Enhancing Planar Lipid Bilayers with a Minimal Actin Cortex.
Daniel L. Burden, Daniel Kim, Wayland W. L. Cheng, Emily Chandler Lawler +2 more
2018Langmuir7 citations
Semantic Scholar
Polyamine Block of Inwardly Rectifying Potassium Channels
H. Kurata, Wayland W. L. Cheng, C. Nichols
2011Methods in molecular biology7 citations Open access
Semantic Scholar
Mapping Two Neursteroid Modulatory Sites in GLIC: A Prototypic Pentameric Ligand Gated Ion Channel
Wayland W. L. Cheng, Zi-Wei Chen, B. John, Melissa M. Budelier +7 more
20182 citations Open access
Semantic Scholar
From Bacteria to Human: Biophysical Studies of Inward Rectifying Potassium Channels
Wayland W. L. Cheng
20122 citations
Semantic Scholar
Structural mechanism of leaflet-specific phospholipid modulation of a pentameric ligand-gated ion channel
John T. Petroff, Noah M. Deitzen, Ezry Santiago-McRae, Brett Deng +11 more
2022bioRxiv1 citations Open access
Semantic Scholar
Polyunsaturated fatty acids inhibit a pentameric ligand‐gated ion channel through one of two specific binding sites
Wayland W. L. Cheng, Noah M. Dietzen, John T. Petroff, D. Covey +1 more
2021The FASEB Journal1 citations
Semantic Scholar
Identification of Neurosteroid Binding Sites on GABA(A) Receptors using Photolabeling with Mass Spectrometry
Zi-Wei Chen, John R. Bracamontes, Wayland W. L. Cheng, Melissa M. Budelier +4 more
20181 citations Open access
Semantic Scholar
Expression and Purification of Recombinant Human Inward Rectifier K+ (KCNJ) Channel
Nazzareno D’Avanzo, Wayland W. L. Cheng, Liang Dong, C. Nichols +1 more
20101 citations Open access
Semantic Scholar
Absolute binding affinities of phospholipids to Erwinia ligand-gated ion channel (ELIC) by streamlined alchemical free energy perturbations (SAFEP).
Ezry Santiago-McRae, John T. Petroff, Wayland W. L. Cheng, Thomas T. Joseph +2 more
2023Biophysical Journal0 citations Open access
Semantic Scholar
Membrane thickness affects ELIC activity & M4 helix structure.
Brandon K. Tan, Wayland W. L. Cheng
2023Biophysical Journal0 citations Open access
Semantic Scholar
Exploring the effects of nanodiscs on the conformation of a pentameric ligand-gated ion channel.
Mark J. Arcario, V. Dalal, Grace Brannigan, Wayland W. L. Cheng
2023Biophysical Journal0 citations
Semantic Scholar
Nanodisc scaffold alters the structure of a pentameric ligand-gated ion channel revealing new conformations.
V. Dalal, John T. Petroff, Noah M. Dietzen, Wayland W. L. Cheng
2023Biophysical Journal0 citations Open access
Semantic Scholar
Membrane phospholipids control activity of the mechanosensitive K2P channel TREK1
P. Schmidpeter, Aboubacar Wague, John T. Petroff, Wayland W. L. Cheng +2 more
2022Biophysical Journal0 citations Open access
Semantic Scholar
Identification of open conformation of a pLGIC stabilized by outer leaflet phospholipid
John T. Petroff, Noah M. Dietzen, Wayland W. L. Cheng
2022Biophysical Journal0 citations Open access
Semantic Scholar
Direct Lipid Binding in a Pentameric Ligand-Gated Ion Channel Assessed by Native Mass Spectrometry
Wayland W. L. Cheng
2019Biophysical Journal0 citations Open access
Semantic Scholar
Cholesterol and Neurosteroids Bind Common Sites but Assume Different Orientations in a Pentameric Ligand Gated Ion Channel
Melissa M. Budelier, Wayland W. L. Cheng, John R. Bracamontes, Zi-Wei Chen +4 more
20180 citations Open access
Semantic Scholar
The Molecular Basis of Phosphoinositide Activation of Human Inward Rectifier (Kir2.1) Channels
Nazzareno D’Avanzo, Sun-Joo Lee, Wayland W. L. Cheng, C. Nichols
20120 citations Open access
Semantic Scholar
Phospholipid Regulation of Purified and Reconstituted Human Inward Rectifier (Kir) Channels
Nazzareno D’Avanzo, Wayland W. L. Cheng, D. Doyle, C. Nichols
20110 citations Open access
Semantic Scholar
Modeling the Liposomal Rubidium Uptake Assay
Wayland W. L. Cheng, N. Panesar, D. Enkvetchakul
20110 citations Open access
Semantic Scholar
The Lipid Dependence of Purified and Reconstituted Kir2.1 and Kir2.2
Wayland W. L. Cheng, Nazzareno D’Avanzo, D. Enkvetchakul, C. Nichols
20100 citations Open access
Semantic Scholar
The E71A Mutation Alters Selective Ion Permeability in KcsA
Wayland W. L. Cheng, C. Nichols
20100 citations Open access
Semantic Scholar
Numerical Fluorescence Correlation Spectroscopy for Molecular Dynamics Analyses Under Non-Standard Conditions | NIST
Michael J. Culbertson, Joshua T. b. Williams, Wayland W. L. Cheng, Dee Ann Stults +3 more
20070 citations
Semantic Scholar

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