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S. Guard · SciRah

Researcher profile · Semantic Scholar

S. Guard

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S. Guard — researcher profile on SciRah

h-index: 13
Works: 33
Citations: 1,109

Most-cited papers

Tachykinin receptor types: Classification and membrane signalling mechanisms.
S. Guard, S. Watson
1991Neurochemistry International349 citations
Semantic Scholar
Stimulation of angiogenesis by substance P and interleukin‐1 in the rat and its inhibition by NK1 or interleukin‐1 receptor antagonists
Tai-Ping D. Fan, D. Hu, S. Guard, G. Gresham +1 more
1993British Journal of Pharmacology145 citations Open access
Semantic Scholar
Pharmacological analysis of [3H]‐senktide binding to NK3 tachykinin receptors in guinea‐pig ileum longitudinal muscle‐myenteric plexus and cerebral cortex membranes
S. Guard, S. P. Watson, J. Maggio, H. Too +1 more
1990British Journal of Pharmacology94 citations Open access
Semantic Scholar
Receptor subtypes or species homologues: relevance to drug discovery.
J. Hall, M. Caulfield, S. P. Watson, S. Guard
1993TIPS - Trends in Pharmacological Sciences84 citations
Semantic Scholar
Efficacy and safety of onabotulinumtoxinA therapy are sustained over 4 years of treatment in patients with neurogenic detrusor overactivity: Final results of a long‐term extension study
M. Kennelly, R. Dmochowski, H. Schulte-Baukloh, K. Ethans +6 more
2017Neurourology and Urodynamics78 citations Open access
Semantic Scholar
The interaction of the NK1 receptor antagonist CP‐96,345 with L‐type calcium channels and its functional consequences
S. Guard, S. Boyle, Kit Wan Tang, K. Watling +2 more
1993British Journal of Pharmacology67 citations Open access
Semantic Scholar
Neurokinin3‐receptors are linked to inositol phospholipid hydrolysis in the guinea‐pig ileum longitudinal muscle‐myenteric plexus preparation
S. Guard, K. Watling, Steve P. Watson
1988British Journal of Pharmacology67 citations Open access
Semantic Scholar
The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair
S. Guard, Z. Poss, C. Ebmeier, Maria Pagratis +3 more
2018Scientific Reports54 citations Open access
Semantic Scholar
Rational design of high affinity tachykinin NK2 receptor antagonists.
S. Boyle, S. Guard, J. Hodgson, D. Horwell +7 more
1994Bioorganic & Medicinal Chemistry28 citations
Semantic Scholar
Proximity biotinylation identifies a set of conformation-specific interactions between Merlin and cell junction proteins
R. Hennigan, Jonathan S. Fletcher, S. Guard, N. Ratner
2019Science Signaling22 citations Open access
Semantic Scholar
Evidence for Two Types of Tachykinin Receptors on Cholinergic Neurons of the Guinea Pig Ileum Myenteric Plexus a
S. Guard, A. McKnight, K. Watling, Steve P. Watson
1991Annals of the New York Academy of Sciences22 citations Open access
Semantic Scholar
Multiomic Analysis Reveals Disruption of Cholesterol Homeostasis by Cannabidiol in Human Cell Lines
S. Guard, Douglas A. Chapnick, Z. Poss, C. Ebmeier +14 more
2020bioRxiv21 citations Open access
Semantic Scholar
Pharmacological characterization of tachykinin‐stimulated inositol phospholipid hydrolysis in peripheral tissues
N. Suman-Chauhan, S. Guard, B. J. Williams, K. Watling
1990British Journal of Pharmacology16 citations Open access
Semantic Scholar
[125i]Neurokinin A labels pharmacologically distinct populations of NK2 binding sites in hamster and rabbit urinary bladder
S. Guard, D. Pain, R. Franks, K. Watling
199312 citations
Semantic Scholar
Label-Free Immunoprecipitation Mass Spectrometry Workflow for Large-scale Nuclear Interactome Profiling.
S. Guard, C. Ebmeier, W. Old
2019Journal of Visualized Experiments11 citations Open access
Semantic Scholar
On the presence of NK2 receptor subtypes in peripheral and central tissues.
K. Watling, S. Guard, J. E. Krause, Y. Takeda +4 more
1993Regulatory Peptides10 citations
Semantic Scholar
An SAR study for the non-peptide substance P receptor (NK1) antagonist, CP-96,345.
W. Howson, J. Hodgson, R. Richardson, L. Walton +2 more
199210 citations
Semantic Scholar
3H-senktide binding in guinea-pig ileum: A comparison with 125I-bolton hunter substance P and 125I-bolton hunter eledoisin☆
S. Guard, K. Watling, S. Watson
19887 citations
Semantic Scholar
Characterisation of [3H]-senktide binding to NK3 tachykinin receptors in guinea-pig ileum and cerebral cortex.
S. Guard, K. Watling, Steve P. Watson
1989British Journal of Pharmacology4 citations
Semantic Scholar
In vitro behavior and UV response of melanocytes derived from carriers of CDKN2A mutations and MC1R variants
B. Hernando, V. Swope, S. Guard, R. Starner +7 more
2018Pigment Cell & Melanoma Research3 citations Open access
Semantic Scholar
693 Consistent long-term efficacy and safety of onabotulinumtoxinA in patients with neurogenic detrusor overactivity: Final results of repeated treatments up to 4 years
G. Karsenty, H. Schulte-Baukloh, R. Dmochowski, K. Ethans +4 more
20143 citations
Semantic Scholar
MP38-01 LONG-TERM EFFICACY AND SAFETY OF REPEAT ONABOTULINUMTOXINA TREATMENT IN OVERACTIVE BLADDER SYNDROME AND URINARY INCONTINENCE: THIRD INTERIM ANALYSIS, MEDIAN 2.4 YEAR FOLLOW-UP
V. Nitti, C. Chapple, D. Sussman, S. Radomski +5 more
20142 citations
Semantic Scholar
MP80-12 SUSTAINED IMPROVEMENTS IN URINARY INCONTINENCE AND QUALITY OF LIFE OVER LONG-TERM TREATMENT WITH ONABOTULINUMTOXINA IN PATIENTS WITH URINARY INCONTINENCE DUE TO NEUROGENIC DETRUSOR OVERACTIVITY
M. Kennelly, R. Dmochowski, H. Schulte-Baukloh, K. Ethans +4 more
20141 citations
Semantic Scholar
P69: Implementing therapeutic drug monitoring of adalimumab in psoriasis: from theory to practice
A. Raharja, Z. Arkir, N. Dand, T. Tsakok +7 more
2021British Journal of Dermatology0 citations
Semantic Scholar
Illuminating DYRK1A Substrates Through a Multi‐omic Drug Based Approach
S. Guard, Z. Poss, C. Ebmeier, Kristofor J. Webb +1 more
2019The FASEB Journal0 citations Open access
Semantic Scholar
121. Consistent long term efficacy and safety of repeat onabotulinumtoxinA injections in patients with neurogenic detrusor overactivity: final results of up to 4 years’ treatment
M. Kennelly, R. Dmochowski, K. Ethans, Courtenay K. Moore +5 more
20150 citations
Semantic Scholar
577 Consistent improvements in urinary urgency following repeat onabotulinumtoxinA treatments in patients with overactive bladder syndrome and urinary incontinence
K. Sievert, C. Chapple, D. Sussman, S. Radomski +5 more
20140 citations
Semantic Scholar
Repeat OnabotulinumtoxinA Treatment in Spinal Cord Injury Patients with Neurogenic Detrusor Overactivity: Final Analysis of 4 Years’ Follow-up Confirms Sustained Safety and Efficacy
M. Kennelly, H. Schulte-Baukloh, R. Dmochowski, K. Ethans +5 more
20140 citations
Semantic Scholar
OnabotulinumtoxinA Demonstrates Similar Improvements in Urinary Incontinence and Quality of Life Regardless of the Use of Clean Intermittent Catheterisation or the Presence of Urinary Tract Infection in Patients with Overactive Bladder
K. Everaert, J. Gruenenfelder, H. Schulte-Baukloh, S. Guard +2 more
20140 citations
Semantic Scholar
MP76-05 REDUCTION IN URINARY INCONTINENCE AND IMPROVEMENT IN QUALITY OF LIFE WITH ONABOTULINUMTOXINA IN OVERACTIVE BLADDER PATIENTS IS UNAFFECTED BY THE USE OF CLEAN INTERMITTENT CATHETERIZATION OR THE PRESENCE OF URINARY TRACT INFECTION
D. Sussman, J. Gruenenfelder, H. Schulte-Baukloh, S. Guard +2 more
20140 citations
Semantic Scholar
Stimulation ofangiogenesis bysubstance Pandinterleukin- 1in theratanditsinhibition byNK1orinterleukin- 1receptor antagonists
S. Guard
19930 citations
Semantic Scholar
Structure-activity requirements of bombesin for GRP- and NMB-preferring bombesin receptors in rat CNS
S. Guard, W. Howson, K. Watling
19930 citations
Semantic Scholar
A study of NK-3 tachykinin receptors
S. Guard
19890 citations
Semantic Scholar

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