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M. Latasa · SciRah

Researcher profile · Semantic Scholar

M. Latasa

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M. Latasa — researcher profile on SciRah

h-index: 29
Works: 76
Citations: 2,586

Most-cited papers

Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma.
Matı́as A. Avila, C. Berasain, E. García-Trevijano, J. Caballería +8 more
2000Journal of Hepatology355 citations Open access
Semantic Scholar
Identification of fibroblast growth factor 15 as a novel mediator of liver regeneration and its application in the prevention of post-resection liver failure in mice
I. Uriarte, M. G. Fernandez-Barrena, M. Monte, M. Latasa +11 more
2013Gut196 citations
Semantic Scholar
Functional proteomics of nonalcoholic steatohepatitis: Mitochondrial proteins as targets of S-adenosylmethionine
E. Santamaría, M. Avila, M. Latasa, Á. Rubio +4 more
2003Proceedings of the National Academy of Sciences of the United States of America175 citations Open access
Semantic Scholar
Fibroblast growth factor 15/19 (FGF15/19) protects from diet-induced hepatic steatosis: development of an FGF19-based chimeric molecule to promote fatty liver regeneration
Gloria Alvarez-Sola, I. Uriarte, M. Latasa, M. G. Fernandez-Barrena +18 more
2017Gut150 citations Open access
Semantic Scholar
The Epidermal Growth Factor Receptor: A Link Between Inflammation and Liver Cancer
C. Berasain, M. J. Perugorria, M. Latasa, J. Castillo +4 more
2009Experimental biology and medicine129 citations
Semantic Scholar
S-adenosylmethionine regulates cytoplasmic HuR via AMP-activated kinase.
M. Martínez-Chantar, M. Vazquez--Chantada, M. Garnacho, M. Latasa +7 more
2006Gastroenterology102 citations
Semantic Scholar
Next-generation sequencing of bile cell-free DNA for the early detection of patients with malignant biliary strictures
M. Arechederra, M. Rullan, I. Amat, D. Oyón +28 more
2021Gut93 citations Open access
Semantic Scholar
Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis
M. Bárcena-Varela, Hannah L. Paish, Laura Álvarez, I. Uriarte +22 more
2020Gut92 citations Open access
Semantic Scholar
Methionine adenosyltransferase II beta subunit gene expression provides a proliferative advantage in human hepatoma.
M. Martínez-Chantar, Elena R. García-Trevijano, M. Latasa, A. Martín-Duce +4 more
2003Gastroenterology86 citations Open access
Semantic Scholar
L-Methionine Availability Regulates Expression of the Methionine Adenosyltransferase 2A Gene in Human Hepatocarcinoma Cells
M. Martínez-Chantar, M. Latasa, M. Varela-Rey, Shelly C. Lu +3 more
2003Journal of Biological Chemistry84 citations Open access
Semantic Scholar
Amphiregulin induces the alternative splicing of p73 into its oncogenic isoform DeltaEx2p73 in human hepatocellular tumors.
J. Castillo, S. Goñi, M. Latasa, M. J. Perugorria +7 more
2009Gastroenterology80 citations
Semantic Scholar
Epidermal Growth Factor Receptor (EGFR) Crosstalks in Liver Cancer
C. Berasain, M. Latasa, R. Urtasun, S. Goñi +5 more
2011Cancers74 citations Open access
Semantic Scholar
Splicing regulator SLU7 is essential for maintaining liver homeostasis.
M. Elizalde, R. Urtasun, M. Azkona, M. Latasa +10 more
2014Journal of Clinical Investigation67 citations Open access
Semantic Scholar
Pilot Multi-Omic Analysis of Human Bile from Benign and Malignant Biliary Strictures: A Machine-Learning Approach
J. Urman, J. M. Herranz, I. Uriarte, M. Rullan +31 more
2020Cancers61 citations Open access
Semantic Scholar
Identification and experimental validation of druggable epigenetic targets in hepatoblastoma.
Alex Clavería-Cabello, J. M. Herranz, M. Latasa, M. Arechederra +22 more
2023Journal of Hepatology56 citations Open access
Semantic Scholar
Regulation of Amphiregulin Gene Expression by β-Catenin Signaling in Human Hepatocellular Carcinoma Cells: A Novel Crosstalk between FGF19 and the EGFR System
M. Latasa, Fabiana Salis, R. Urtasun, O. García‐Irigoyen +8 more
2012PLoS ONE55 citations Open access
Semantic Scholar
Wilms' tumor 1 gene expression in hepatocellular carcinoma promotes cell dedifferentiation and resistance to chemotherapy.
M. J. Perugorria, J. Castillo, M. Latasa, S. Goñi +5 more
2009Cancer Research54 citations Open access
Semantic Scholar
Transformed but not normal hepatocytes express UCP2
M. Carretero, L. Torres, M. Latasa, Elena R. Garcı́a-Trevijano +3 more
1998FEBS Letters54 citations Open access
Semantic Scholar
S-Adenosylmethionine revisited: its essential role in the regulation of liver function.
Matiías A Avila, E. García-Trevijano, M. Martínez-Chantar, M. Latasa +5 more
2002Alcohol50 citations
Semantic Scholar
Impairment of pre-mRNA splicing in liver disease: mechanisms and consequences.
C. Berasain, S. Goñi, J. Castillo, M. Latasa +2 more
2010World Journal of Gastroenterology48 citations Open access
Semantic Scholar
Bile acids, FGF15/19 and liver regeneration: From mechanisms to clinical applications.
Gloria Alvarez-Sola, I. Uriarte, M. Latasa, Maddalen Jiménez +9 more
2017Biochimica et Biophysica Acta - Molecular Basis of Disease47 citations Open access
Semantic Scholar
Dual Targeting of G9a and DNA Methyltransferase‐1 for the Treatment of Experimental Cholangiocarcinoma
L. Colyn, M. Bárcena-Varela, Gloria Alvarez-Sola, M. Latasa +32 more
2020Hepatology46 citations
Semantic Scholar
Fibroblast Growth Factor 15/19 in Hepatocarcinogenesis
Gloria Alvarez-Sola, I. Uriarte, M. Latasa, R. Urtasun +8 more
2017Digestive Diseases43 citations
Semantic Scholar
Lack of Abcc3 expression impairs bile-acid induced liver growth and delays hepatic regeneration after partial hepatectomy in mice.
M. G. Fernandez-Barrena, M. Monte, M. Latasa, I. Uriarte +8 more
2012Journal of Hepatology43 citations
Semantic Scholar
Toll-like receptor-4 expression by hepatic progenitor cells and biliary epithelial cells in HCV-related chronic liver disease
U. Vespasiani-Gentilucci, S. Carotti, A. Onetti‐Muda, G. Perrone +6 more
2011Modern Pathology34 citations Open access
Semantic Scholar
Identification of PRMT5 as a therapeutic target in cholangiocarcinoma
J. Elurbide, L. Colyn, M. Latasa, I. Uriarte +27 more
2024Gut33 citations Open access
Semantic Scholar
New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming
L. Colyn, Gloria Alvarez-Sola, M. Latasa, I. Uriarte +30 more
2022Journal of experimental & clinical cancer research : CR33 citations Open access
Semantic Scholar
Oral Methylthioadenosine Administration Attenuates Fibrosis and Chronic Liver Disease Progression in Mdr2−/− Mice
M. Latasa, C. Gil-Puig, M. G. Fernandez-Barrena, C. Rodríguez-Ortigosa +13 more
2010PLoS ONE30 citations Open access
Semantic Scholar
Engineered fibroblast growth factor 19 protects from acetaminophen-induced liver injury and stimulates aged liver regeneration in mice
Gloria Alvarez-Sola, I. Uriarte, M. Latasa, Maddalen Jiménez +13 more
2017Cell Death and Disease29 citations Open access
Semantic Scholar
DNA methylation and histone acetylation of rat methionine adenosyltransferase 1A and 2A genes is tissue-specific.
L. Torres, G. López-Rodas, M. Latasa, M. Carretero +5 more
2000International Journal of Biochemistry and Cell Biology25 citations Open access
Semantic Scholar
The epidermal growth factor receptor ligand amphiregulin is a negative regulator of hepatic acute-phase gene expression.
A. Pardo-Saganta, M. Latasa, J. Castillo, L. Alvarez-Asiain +7 more
2009Journal of Hepatology22 citations
Semantic Scholar
Redox regulation of methylthioadenosine phosphorylase in liver cells: molecular mechanism and functional implications.
J. Fernández-Irigoyen, M. Santamaria, Virginia Sanchez-Quiles, M. Latasa +7 more
2008Biochemical Journal19 citations Open access
Semantic Scholar
Targeting of the G9a, DNMT1 and UHRF1 epigenetic complex as an effective strategy against pancreatic ductal adenocarcinoma
D. Oyón, A. López-Pascual, Borja Castelló-Uribe, I. Uriarte +24 more
2025Journal of experimental & clinical cancer research : CR18 citations Open access
Semantic Scholar
Comprehensive analysis of epigenetic and epitranscriptomic genes’ expression in human NAFLD
J. M. Herranz, A. López-Pascual, Alex Clavería-Cabello, I. Uriarte +9 more
2023Journal of physiology and biochemistry18 citations Open access
Semantic Scholar
Dual Pharmacological Targeting of HDACs and PDE5 Inhibits Liver Disease Progression in a Mouse Model of Biliary Inflammation and Fibrosis
Alex Clavería-Cabello, L. Colyn, I. Uriarte, M. Latasa +13 more
2020Cancers12 citations Open access
Semantic Scholar
Fragile X mental retardation protein in intrahepatic cholangiocarcinoma: regulating the cancer cell behavior plasticity at the leading edge
S. Carotti, M. Zingariello, M. Francesconi, L. D'Andrea +14 more
2021Oncogene11 citations Open access
Semantic Scholar
Alterations in the expression and activity of pre-mRNA splicing factors in hepatocarcinogenesis.
C. Berasain, M. Elizalde, R. Urtasun, J. Castillo +5 more
2014Hepatic Oncology11 citations Open access
Semantic Scholar
FGF21 and APOA1 mRNA-based therapies for the treatment of experimental acute pancreatitis
A. López-Pascual, Eva Santamaría, N. Ardaiz, I. Uriarte +15 more
2025Journal of Translational Medicine8 citations Open access
Semantic Scholar
Expression landscape of epigenetic genes in human hepatocellular carcinoma
Borja Castelló-Uribe, A. López-Pascual, J. Elurbide, Elena Adán-Villaescusa +9 more
2025Journal of physiology and biochemistry8 citations Open access
Semantic Scholar
New insights into the regulation of bile acids synthesis during the early stages of liver regeneration: A human and experimental study.
I. Uriarte, Eva Santamaría, A. López-Pascual, Maria J. Monte +20 more
2024Biochimica et Biophysica Acta - Molecular Basis of Disease8 citations Open access
Semantic Scholar
Activation of the Unfolded Protein Response (UPR) Is Associated with Cholangiocellular Injury, Fibrosis and Carcinogenesis in an Experimental Model of Fibropolycystic Liver Disease
Chaobo Chen, Hanghang Wu, Hui-qing Ye, A. Tortajada +25 more
2021Cancers5 citations Open access
Semantic Scholar
Lack of Abcc 3 expression impairs bile-acid induced liver growth and delays hepatic regeneration after partial hepatectomy in mice
M. G. Fernandez-Barrena, M. Monte, M. Latasa, I. Uriarte +8 more
20115 citations
Semantic Scholar
SLU7 is a survival factor for cancer cells working as a mitotic regulator
Maddalen Jiménez, R. Urtasun, M. Elizalde, M. Azkona +5 more
20174 citations
Semantic Scholar
Epidermal growth factor receptor ligands in murine models for erythropoietic protoporphyria: potential novel players in the progression of liver injury.
C. Berasain, A. Sampedro, I. Mauleón, S. Goñi +9 more
2009Cellular and Molecular Biology4 citations
Semantic Scholar
Histone methyl-transferase G9a inhibition boosts the efficacy of immune checkpoint inhibitors in experimental hepatocellular carcinoma
Elena Adán-Villaescusa, Borja Castelló-Uribe, I. Uriarte, Eva Santamaría +19 more
2025bioRxiv3 citations Open access
Semantic Scholar
Caspases compromise SLU7 and UPF1 stability and NMD activity during hepatocarcinogenesis
Carla Rojo, María Gárate-Rascón, M. Recalde, Ane Álava +11 more
2024JHEP Reports3 citations Open access
Semantic Scholar
Histone methyl-transferase G9a inhibition boosts the efficacy of immune checkpoint inhibitors in experimental hepatocellular carcinoma
Elena Adán-Villaescusa, Borja Castelló-Uribe, I. Uriarte, Eva Santamaría +27 more
2026Cell Reports Medicine2 citations Open access
Semantic Scholar
Development of a New Hepatoprotective and Proregenerative Molecule Based on Fibroblast Growth Factor 15/19
Gloria Alvarez-Sola, I. Uriarte, M. Latasa, M. Elizalde +8 more
20162 citations
Semantic Scholar
O096 : Matrix metalloproteinase-10 contributes to hepatocellular carcinoma development in a novel crosstalk with stromal derived growth factor 1/C-X-C chemokine receptor 4 axis
O. García‐Irigoyen, M. Latasa, S. Carotti, I. Uriarte +13 more
20152 citations
Semantic Scholar
16 - TREFOIL FACTOR-3 IS A HYPOXIA-TRIGGERED PRO-TUMORIGENIC FACTOR IN HEPATOBLASTOMA
J. Elurbide, M. Latasa, I. Uriarte, A. López-Pascual +19 more
2026Gastroenterology & hepatology0 citations
Semantic Scholar

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C. Berasain×40
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C. Berasain — researcher profile on SciRah
M. Avila×32
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M. G. Fernandez-Barrena×29
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