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I. Mauleón · SciRah

Researcher profile · Semantic Scholar

I. Mauleón

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I. Mauleón — researcher profile on SciRah

h-index: 14
Works: 28
Citations: 734

Most-cited papers

Oxaliplatin in combination with liver-specific expression of interleukin 12 reduces the immunosuppressive microenvironment of tumours and eradicates metastatic colorectal cancer in mice
Manuela Gonzalez-Aparicio, P. Alzuguren, I. Mauleón, J. Medina-Echeverz +7 more
2010Gut109 citations Open access
Semantic Scholar
Effect of Adeno-Associated Virus Serotype and Genomic Structure on Liver Transduction and Biodistribution in Mice of Both Genders
A. Pañeda, L. Vanrell, I. Mauleón, J. Crettaz +9 more
2009Human Gene Therapy108 citations
Semantic Scholar
Safety and Liver Transduction Efficacy of rAAV5-cohPBGD in Nonhuman Primates: A Potential Therapy for Acute Intermittent Porphyria
A. Pañeda, Esperanza López-Franco, Christine Kaeppel, Carmen Unzu +19 more
2013Human Gene Therapy68 citations Open access
Semantic Scholar
Transient and intensive pharmacological immunosuppression fails to improve AAV-based liver gene transfer in non-human primates
Carmen Unzu, S. Hervás-Stubbs, A. Sampedro, I. Mauleón +9 more
2012Journal of Translational Medicine67 citations Open access
Semantic Scholar
MYC in Chronic Myeloid Leukemia: Induction of Aberrant DNA Synthesis and Association with Poor Response to Imatinib
M. Albajar, M. Gómez-Casares, Javier Llorca, I. Mauleón +6 more
2011Molecular Cancer Research65 citations Open access
Semantic Scholar
Sustained enzymatic correction by rAAV-mediated liver gene therapy protects against induced motor neuropathy in acute porphyria mice.
Carmen Unzu, A. Sampedro, I. Mauleón, M. Alegre +10 more
2011Molecular Therapy62 citations Open access
Semantic Scholar
Myc Antagonizes Ras-mediated Growth Arrest in Leukemia Cells through the Inhibition of the Ras-ERK-p21Cip1 Pathway*
J. Vaqué, J. Navascués, Y. Shiio, M. Laiho +5 more
2005Journal of Biological Chemistry44 citations Open access
Semantic Scholar
Intrahepatic injection of adenovirus reduces inflammation and increases gene transfer and therapeutic effect in mice
J. Crettaz, P. Berraondo, I. Mauleón, L. Ochoa +8 more
2006Hepatology42 citations Open access
Semantic Scholar
Intensive pharmacological immunosuppression allows for repetitive liver gene transfer with recombinant adenovirus in nonhuman primates.
A. Fontanellas, S. Hervás-Stubbs, I. Mauleón, J. Dubrot +11 more
2010Molecular Therapy33 citations Open access
Semantic Scholar
Porphobilinogen deaminase over-expression in hepatocytes, but not in erythrocytes, prevents accumulation of toxic porphyrin precursors in a mouse model of acute intermittent porphyria.
Carmen Unzu, A. Sampedro, I. Mauleón, L. Vanrell +6 more
2010Journal of Hepatology32 citations
Semantic Scholar
Helper-dependent adenoviral liver gene therapy protects against induced attacks and corrects protein folding stress in acute intermittent porphyria mice.
Carmen Unzu, A. Sampedro, I. Mauleón, Manuela Gonzalez-Aparicio +4 more
2013Human Molecular Genetics24 citations
Semantic Scholar
Kinetics of myc‐max‐mad gene expression during hepatocyte proliferation in vivo: Differential regulation of mad family and stress‐mediated induction of c‐myc
I. Mauleón, M. Lombard, Maria J. Muñoz-Alonso, Matilde Canelles +1 more
2004Molecular Carcinogenesis23 citations
Semantic Scholar
Renal Failure Affects the Enzymatic Activities of the Three First Steps in Hepatic Heme Biosynthesis in the Acute Intermittent Porphyria Mouse
Carmen Unzu, A. Sampedro, E. Sardh, I. Mauleón +5 more
2012PLoS ONE17 citations Open access
Semantic Scholar
Interleukin-12 inhibits liver-specific drug-inducible systems in vivo
M. Reboredo, M. Zabala, I. Mauleón, J De Las Rivas +5 more
2008Gene Therapy17 citations Open access
Semantic Scholar
[383] INTRAHEPATIC INJECTION OF ADENOVIRUS REDUCES INFLAMMATION AND INCREASES GENE TRANSFER AND THERAPEUTIC EFFECT IN MICE
Julien Crettaz, P. Berraondo, I. Mauleón, L. Ochoa +8 more
20076 citations Open access
Semantic Scholar
Gene Therapy in Combination with Nitrogen Scavenger Pretreatment Corrects Biochemical and Behavioral Abnormalities of Infant Citrullinemia Type 1 Mice
Andrea Bazo, Aquilino Lantero, I. Mauleón, L. Neri +7 more
2022International Journal of Molecular Sciences5 citations Open access
Semantic Scholar
Vitamin D-binding protein as a biomarker of active disease in acute intermittent porphyria.
Irantzu Serrano-Mendioroz, A. Sampedro, M. I. Mora, I. Mauleón +6 more
2015Journal of Proteomics4 citations
Semantic Scholar
Epidermal growth factor receptor ligands in murine models for erythropoietic protoporphyria: potential novel players in the progression of liver injury.
C. Berasain, A. Sampedro, I. Mauleón, S. Goñi +9 more
2009Cellular and Molecular Biology4 citations
Semantic Scholar
Transient and intensive pharmacological immunosuppression fails to improve AAV-based liver gene transfer in non-human primates
Carmen Unzu, S. Hervás-Stubbs, A. Sampedro, I. Mauleón +9 more
2012Journal of Translational Medicine2 citations Open access
Semantic Scholar
Oxaliplatin in combination with liver-specific expression of interleukin-12 reduces the immunosuppressive microenvironment of tumors and eradicates metastatic colorectal cancer in mice
Manuela Gonzalez-Aparicio, P. Alzuguren, I. Mauleón, -. JoseMedina +10 more
20102 citations
Semantic Scholar
In Vivo Selection of S/MAR Sequences to Favour AAV Episomal Maintenance in Dividing Cells
Andrea Llanos-Ardaiz, Aquilino Lantero, L. Neri, I. Mauleón +6 more
2024International Journal of Molecular Sciences1 citations Open access
Semantic Scholar
Orthogonal characterization of rAAV reveals vector attributes that drive ITR repair, self-complementary genome formation, and transgene expression
Carla Llinares, Suk Namkung, Mitchell Yip, Á. Vales +7 more
2026Molecular Therapy: Nucleic Acids0 citations Open access
Semantic Scholar
O-162 Hydatidosis: A reemerging neglected disease
M. Pomar, E. Castells, M. Ferrer, S. Gómez +4 more
2023Animal - science proceedings0 citations
Semantic Scholar
137 TOXICOLOGY AND LIVER TRANSDUCTION EFFICACY EVALUATION OF A RECOMBINANT ADENO-ASSOCIATED VIRAL VECTOR IN NON HUMAN PRIMATES AS A POTENTIAL TREATMENT FOR ACUTE INTERMITTENT PORPHYRIA
A. Pañeda, Esperanza López-Franco, A. Fontanellas, Carmen Unzu +12 more
20120 citations
Semantic Scholar
1134 AAV MEDIATED LIVER GENE THERAPY PROVIDES PROLONGED ENZYMATIC CORRECTION AND PROTECTS AGAINST INDUCED MOTOR NEUROPATHY IN ACUTE INTERMITTENT PORPHYRIA MICE
Carmen Unzu, A. Sampedro, I. Mauleón, M. Alegre +12 more
20100 citations
Semantic Scholar
274. Antitumor Effect of Controlled Expression of Interleukin-12 in a Murine Model of Liver Metastases
I. Mauleón, J. Crettaz, G. González-Aseguinolaza, M. Zabala +4 more
20060 citations Open access
Semantic Scholar
547. Improvement of Liver Gene Transfer by First and Third Generation Adenoviral Vectors
J. Crettaz, P. Berraondo, I. Mauleón, L. Ochoa +9 more
20050 citations Open access
Semantic Scholar
580. Inducible expression of interleukin-12 for the treatment of liver metastases using a high-capacity adenoviral vector
R. Hernández-Alcoceba, I. Mauleón, M. Zabala, V. Shankar +3 more
20040 citations Open access
Semantic Scholar

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