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T. Crumley · SciRah

Researcher profile · Semantic Scholar

T. Crumley

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T. Crumley — researcher profile on SciRah

h-index: 15
Works: 28
Citations: 1,466

Most-cited papers

Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase.
Sandra J. Darkin-Rattray, A. Gurnett, R. W. Myers, P. Dulski +11 more
1996Proceedings of the National Academy of Sciences of the United States of America562 citations Open access
Semantic Scholar
Suppression of Niacin‐induced Vasodilation with an Antagonist to Prostaglandin D2 Receptor Subtype 1
E. Lai, I. de Lepeleire, T. Crumley, Fang Liu +6 more
2007Clinical pharmacology and therapy159 citations
Semantic Scholar
Purification and Molecular Characterization of cGMP-dependent Protein Kinase from Apicomplexan Parasites
A. Gurnett, P. Liberator, P. Dulski, S. Salowe +16 more
2002Journal of Biological Chemistry116 citations Open access
Semantic Scholar
Pharmacokinetics of Aprepitant After Single and Multiple Oral Doses in Healthy Volunteers
Anup K. Majumdar, L. Howard, M. R. Goldberg, L. Hickey +13 more
2006Journal of clinical pharmacology104 citations
Semantic Scholar
Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure-activity relationships of apicidin. Part 1.
S. Colletti, R. W. Myers, Sandra J. Darkin-Rattray, A. Gurnett +12 more
2001Bioorganic & Medicinal Chemistry Letters67 citations Open access
Semantic Scholar
Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure-activity relationships of apicidin. Part 2.
S. Colletti, R. W. Myers, Sandra J. Darkin-Rattray, A. Gurnett +12 more
2001Bioorganic & Medicinal Chemistry Letters66 citations Open access
Semantic Scholar
Effect of aprepitant on the pharmacokinetics and pharmacodynamics of warfarin
M. Depre, A. van Hecken, M. Oeyen, I. de Lepeleire +8 more
2005European Journal of Clinical Pharmacology63 citations
Semantic Scholar
A Microdose Cocktail to Evaluate Drug Interactions in Patients with Renal Impairment
D. Tatosian, Ka L. Yee, Zufei Zhang, Kate Mostoller +20 more
2020Clinical pharmacology and therapy52 citations
Semantic Scholar
Synthesis and SAR of 2,3-diarylpyrrole inhibitors of parasite cGMP-dependent protein kinase as novel anticoccidial agents.
T. Biftu, D. Feng, M. Ponpipom, N. Girotra +21 more
2005Bioorganic & Medicinal Chemistry Letters47 citations Open access
Semantic Scholar
The effect of MK-0524, a prostaglandin D2 receptor antagonist, on prostaglandin D2-induced nasal airway obstruction in healthy volunteers
A. van Hecken, M. Depre, I. de Lepeleire, C. Thach +11 more
2007European Journal of Clinical Pharmacology38 citations
Semantic Scholar
Effects of lorazepam on fear-potentiated startle responses in man
S. Graham, J. Scaife, R. W. Langley, C. Bradshaw +6 more
2005Journal of Psychopharmacology36 citations
Semantic Scholar
Absorption, Metabolism, and Excretion of [14C]MK-0524, a Prostaglandin D2 Receptor Antagonist, in Humans
B. Karanam, Maria Madeira, S. Bradley, Larissa A. Wenning +10 more
2007Drug Metabolism And Disposition27 citations
Semantic Scholar
Safety and immunogenicity of intramuscular, single-dose V590 (rVSV-SARS-CoV-2 Vaccine) in healthy adults: Results from a phase 1 randomised, double-blind, placebo-controlled, dose-ranging trial
Jonathan A. Robbins, D. Tait, Qinlei Huang, Sheri A. Dubey +21 more
2022EBioMedicine26 citations Open access
Semantic Scholar
Synthesis and SAR studies of diarylpyrrole anticoccidial agents.
Xiaoxia Qian, Gui-Bai Liang, D. Feng, M. Fisher +12 more
2006Bioorganic & Medicinal Chemistry Letters20 citations Open access
Semantic Scholar
Pharmacokinetic-pharmacodynamic studies of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor MK-0916 in healthy subjects.
D. Wright, J. Stone, T. Crumley, Larissa A. Wenning +11 more
2013British Journal of Clinical Pharmacology18 citations Open access
Semantic Scholar
N-alkyl-4-piperidinyl-2,3-diarylpyrrole derivatives with heterocyclic substitutions as potent and broad spectrum anticoccidial agents.
Gui-Bai Liang, Xiaoxia Qian, D. Feng, M. Fisher +12 more
2008Bioorganic & Medicinal Chemistry Letters15 citations Open access
Semantic Scholar
Isolation, structure, and coccidiostat activity of coccidiostatin A.
H. Jayasuriya, Zi-Qiang Guan, A. Dombrowski, G. Bills +10 more
2007Journal of Natural Products14 citations
Semantic Scholar
The Effect of Etoricoxib on the Pharmacokinetics of Oral Contraceptives in Healthy Participants
J. Schwartz, T. Hunt, William B. Smith, P. Wong +5 more
2009Journal of clinical pharmacology12 citations
Semantic Scholar
Hydroxylated N-alkyl-4-piperidinyl-2,3-diarylpyrrole derivatives as potent broad-spectrum anticoccidial agents.
Gui-Bai Liang, Xiaoxia Qian, T. Biftu, D. Feng +12 more
2005Bioorganic & Medicinal Chemistry Letters10 citations Open access
Semantic Scholar
RECEPTOR ANTAGONIST, IN HUMANS
B. Karanam, Maria Madeira, S. Bradley, Larissa A. Wenning +10 more
20075 citations
Semantic Scholar
Gefapixant as a P2X3 receptor antagonist treatment for obstructive sleep apnea: a randomized controlled trial
Jonathan A. Robbins, S. Sands, L. Maganti, T. Crumley +10 more
2024Journal of Clinical Sleep Medicine (JCSM)3 citations
Semantic Scholar
“In‐House” Data on the Outside—A Mobile Health Approach
Qinlei Huang, T. Crumley, C. Walters, L. Cluckers +8 more
2020Clinical pharmacology and therapy2 citations
Semantic Scholar
Single Therapeutic and Supratherapeutic Doses of Laropiprant, a Selective Prostaglandin D2 Receptor 1 Antagonist, Do Not Prolong the QTcF Interval in Healthy Volunteers
W. Luo, T. Crumley, D. Ebel, G. Atiee +4 more
2010Journal of clinical pharmacology2 citations
Semantic Scholar
Effects of Extended-Release Niacin and Extended-Release Niacin/Laropiprant on the Pharmacokinetics of Simvastatin in Healthy Subjects
Brett Lauring, V. Dishy, Pieter-Jan de Kam, T. Crumley +5 more
2015American Journal of Therapeutics1 citations
Semantic Scholar
Mobile health technology captures 'in-house' data on the outside : an assessment with pharmacological intervention
Gaurav Bhatia, Q. Huang, T. Crumley, C. Walters +7 more
20190 citations
Semantic Scholar
LBOVI‐A‐3
S. Stoch, W. Tanaka, D. Hilliard, D. Chappell +10 more
20060 citations
Semantic Scholar
Abstract 344: Suppression of Niacin Induced Flushing Symptoms with a DP1 Receptor Antagonist
E. Lai, T. Crumley, Fang Liu, Larissa A. Wenning +5 more
20060 citations
Semantic Scholar
Bmc Medical Research Methodology Open Access Which Resources Should Be Used to Identify Rct/ccts for Systematic Reviews: a Systematic Review
E. Crumley, N. Wiebe, Kristie Cramer, Terry P. Klassen +8 more
0 citations
Semantic Scholar

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A. Gurnett×8
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Larissa A. Wenning — researcher profile on SciRah