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Silvia Maioli · SciRah

Researcher profile · Semantic Scholar

Silvia Maioli

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Silvia Maioli — researcher profile on SciRah

h-index: 20
Works: 58
Citations: 1,512

Most-cited papers

Alterations in cholesterol metabolism as a risk factor for developing Alzheimer's disease: Potential novel targets for treatment.
Raul Loera-Valencia, Julen Goikolea, Cristina Parrado-Fernández, Paula Merino-Serrais +1 more
2019Journal of Steroid Biochemistry and Molecular Biology207 citations Open access
Semantic Scholar
Estrogen receptors and the aging brain
Silvia Maioli, K. Leander, P. Nilsson, I. Nalvarte
2021Essays in Biochemistry113 citations Open access
Semantic Scholar
Cross-disease analysis of Alzheimer’s disease and type-2 Diabetes highlights the role of autophagy in the pathophysiology of two highly comorbid diseases
L. Caberlotto, T. Nguyen, M. Lauria, C. Priami +7 more
2019Scientific Reports99 citations Open access
Semantic Scholar
Is It Possible to Improve Memory Function by Upregulation of the Cholesterol 24S-Hydroxylase (CYP46A1) in the Brain?
Silvia Maioli, Ann Båvner, Zeina Ali, M. Heverin +8 more
2013PLoS ONE80 citations Open access
Semantic Scholar
Alterations in brain leptin signalling in spite of unchanged CSF leptin levels in Alzheimer’s disease
Silvia Maioli, Maria Lodeiro, Paula Merino-Serrais, F. Falahati +9 more
2014Aging Cell78 citations Open access
Semantic Scholar
27-Hydroxycholesterol impairs neuronal glucose uptake through an IRAP/GLUT4 system dysregulation
M. Ismail, Laura Mateos, Silvia Maioli, Paula Merino-Serrais +10 more
2017Journal of Experimental Medicine73 citations Open access
Semantic Scholar
The composition of polypharmacy: A register-based study of Swedes aged 75 years and older
J. Wastesson, A. Cedazo-Mínguez, J. Fastbom, Silvia Maioli +1 more
2018PLoS ONE67 citations Open access
Semantic Scholar
Aggregation of the Inflammatory S100A8 Precedes A&bgr; Plaque Formation in Transgenic APP Mice: Positive Feedback for S100A8 and A&bgr; Productions
Maria Lodeiro, E. Puerta, M. Ismail, Patricia Rodriguez-Rodriguez +7 more
2016The journals of gerontology. Series A, Biological sciences and medical sciences64 citations
Semantic Scholar
Statins and cognitive decline in patients with Alzheimer’s and mixed dementia: a longitudinal registry-based cohort study
B. Petek, H. Häbel, Hong Xu, M. Villa-Lopez +9 more
2023Alzheimer's Research & Therapy63 citations Open access
Semantic Scholar
Brain Renin–Angiotensin System as Novel and Potential Therapeutic Target for Alzheimer’s Disease
Raul Loera-Valencia, Francesca Eroli, S. García-Ptacek, Silvia Maioli
2021International Journal of Molecular Sciences63 citations Open access
Semantic Scholar
27-hydroxycholesterol mediates negative effects of dietary cholesterol on cognition in mice.
M. Heverin, Silvia Maioli, T. Pham, Laura Mateos +5 more
2015Behavioural Brain Research63 citations
Semantic Scholar
27-Hydroxycholesterol Induces Aberrant Morphology and Synaptic Dysfunction in Hippocampal Neurons
Paula Merino-Serrais, Raul Loera-Valencia, Patricia Rodriguez-Rodriguez, Cristina Parrado-Fernández +7 more
2018Cerebral Cortex62 citations Open access
Semantic Scholar
Combination of Apolipoprotein E4 and High Carbohydrate Diet Reduces Hippocampal BDNF and Arc Levels and Impairs Memory in Young Mice
Silvia Maioli, E. Puerta, Paula Merino-Serrais, Laura Fusari +3 more
2012Journal of Alzheimer's Disease46 citations
Semantic Scholar
Intranasal delivery of pro-resolving lipid mediators rescues memory and gamma oscillation impairment in AppNL-G-F/NL-G-F mice
Ceren Emre, L. Arroyo-García, Khanh V. Do, Bokkyoo Jun +9 more
2022Communications Biology45 citations Open access
Semantic Scholar
Apolipoprotein E4 Elicits Lysosomal Cathepsin D Release, Decreased Thioredoxin-1 Levels, and Apoptosis
Torbjörn Persson, Francesca Lattanzio, Javier Calvo-Garrido, R. Rimondini +5 more
2016Journal of Alzheimer's Disease39 citations Open access
Semantic Scholar
Hypercholesterolemia and 27-Hydroxycholesterol Increase S100A8 and RAGE Expression in the Brain: a Link Between Cholesterol, Alarmins, and Neurodegeneration
Raul Loera-Valencia, M. Ismail, Julen Goikolea, Maria Lodeiro +8 more
2021Molecular Neurobiology32 citations Open access
Semantic Scholar
Antidepressant use and cognitive decline in patients with dementia: a national cohort study
M. Mo, T. Abzhandadze, M. Hoang, Simona F. Sacuiu +8 more
2025BMC Medicine31 citations Open access
Semantic Scholar
CYP46A1-mediated cholesterol turnover induces sex-specific changes in cognition and counteracts memory loss in ovariectomized mice
María Latorre-Leal, Patricia Rodriguez-Rodriguez, L. Franchini, Orestis Nikolidakis +18 more
2024Science Advances31 citations Open access
Semantic Scholar
A metagenomic study of gut viral markers in amyloid-positive Alzheimer’s disease patients
M. Ghorbani, D. Ferreira, Silvia Maioli
2023Alzheimer's Research & Therapy26 citations Open access
Semantic Scholar
27‐hydroxycholesterol promotes oligodendrocyte maturation: Implications for hypercholesterolemia‐associated brain white matter changes
Vilma Alanko, A. Gaminde-Blasco, Tania Quintela-López, Raul Loera-Valencia +10 more
2023Glia22 citations Open access
Semantic Scholar
5-HT1B and other related serotonergic proteins are altered in APPswe mutation.
Walid Tajeddinn, Torbjörn Persson, Silvia Maioli, Javier Calvo-Garrido +8 more
2015Neuroscience Letters19 citations Open access
Semantic Scholar
Serum Thioredoxin-80 is associated with age, ApoE4, and neuropathological biomarkers in Alzheimer’s disease: a potential early sign of AD
Julen Goikolea, G. Gereñu, M. Daniilidou, F. Mangialasche +8 more
2022Alzheimer's Research & Therapy17 citations Open access
Semantic Scholar
Chronic polypharmacy impairs explorative behavior and reduces synaptic functions in young adult mice
Francesca Eroli, K. Johnell, María Latorre Leal, Chiara Adamo +4 more
2020Aging17 citations Open access
Semantic Scholar
SIRT2 Inhibition Rescues Neurodegenerative Pathology but Increases Systemic Inflammation in a Transgenic Mouse Model of Alzheimer’s Disease
Noemi Sola-Sevilla, Alberto Mesa-Lombardo, M. Aleixo, Sara Expósito +12 more
2023Journal of Neuroimmune Pharmacology16 citations Open access
Semantic Scholar
Bioenergetics and lipid metabolism in Alzheimer's disease: From cell biology to systemic health
Silvia Maioli, I. Nalvarte, M. Ankarcrona, M. Schultzberg +9 more
2025Journal of Internal Medicine14 citations Open access
Semantic Scholar
Dynamic microglia alterations associate with hippocampal network impairments: A turning point in amyloid pathology progression.
Giusy Pizzirusso, Efthalia Preka, Julen Goikolea, Celia Aguilar-Ruiz +11 more
2024Brain, behavior, and immunity14 citations Open access
Semantic Scholar
Pharmacological Modulations of the Serotonergic System in a Cell-Model of Familial Alzheimer’s Disease
Walid Tajeddinn, Torbjörn Persson, Javier Calvo-Garrido, Mohammed Seed Ahmed +11 more
2016Journal of Alzheimer's Disease14 citations
Semantic Scholar
Atrophy trajectories in Alzheimer’s disease: how sex matters
Anna Inguanzo, Konstantinos Poulakis, Javier Oltra, Silvia Maioli +4 more
2025Alzheimer's Research & Therapy12 citations Open access
Semantic Scholar
Alzheimer’s disease biomarker profiling in a memory clinic cohort without common comorbidities
M. Daniilidou, Francesca Eroli, Vilma Alanko, Julen Goikolea +16 more
2022bioRxiv12 citations Open access
Semantic Scholar
Different effects of CYP27A1 and CYP7B1 on cognitive function: Two mouse models in comparison
Julen Goikolea, María Latorre-Leal, Christina Tsagkogianni, Sonja Pikkupeura +6 more
202311 citations
Semantic Scholar
Medications and cognitive decline in Alzheimer's disease: Cohort cluster analysis of 15,428 patients
Pol Grau-Jurado, S. Mostafaei, Hong Xu, M. Mo +9 more
2025Journal of Alzheimer's Disease8 citations Open access
Semantic Scholar
Impaired astrocytic synaptic function by peripheral cholesterol metabolite 27-hydroxycholesterol
Fokion Spanos, G. Gereñu, Julen Goikolea, María Latorre-Leal +9 more
2024Frontiers in Cellular Neuroscience8 citations Open access
Semantic Scholar
Cholesterol metabolism and oxysterols in neurodegenerative disorders: spotlight on Alzheimer's disease
Ljerka Delac, Silvia Maioli
2025Current Opinion in Endocrine and Metabolic Research7 citations Open access
Semantic Scholar
ERβ mediates sex-specific protection in the App-NL-G-F mouse model of Alzheimer’s disease
Aphrodite Demetriou, Birgitta Lindqvist, Heba G. Ali, Mohamed M. Shamekh +5 more
2025Biology of Sex Differences6 citations Open access
Semantic Scholar
Reactive Astrocytes with Reduced Function of Glutamate Transporters in the App NL‑G‑F Knock-in Mice
Ipsit Srivastava, Julen Goikolea, Tamer Ayberk Kaya, María Latorre-Leal +10 more
2025ACS Chemical Neuroscience6 citations Open access
Semantic Scholar
Exploring biomarkers of neurodegenerative risk: associations of oxysterols, sex hormones, and reproductive characteristics in older women
Michelle M. Dunk, Ljerka Delac, Stephen R. Rapp, I. Driscoll +12 more
2025Journal of Lipid Research5 citations Open access
Semantic Scholar
Statins, cholesterol and cognition at the time of Alzheimer's disease diagnosis: A cross-sectional study from the Swedish registry for cognitive/dementia disorders
B. Petek, M. Mo, Hong Xu, Jakob Norgren +12 more
2025Journal of Alzheimer's disease reports4 citations Open access
Semantic Scholar
27-Hydroxycholesterol Promotes Oligodendrocyte Maturation – Implications for Hypercholesterolemia Associated Brain White Matter Changes
Vilma Alanko, Tania Quintela-López, A. Gaminde-Blasco, Raul Loera-Valencia +10 more
20214 citations Open access
Semantic Scholar
Elevated 24-hydroxycholesterol levels counteract okadaic acid-induced tau hyperphosphorylation and neuronal morphology impairment.
S. Giannelli, Francesca Eroli, Raul Loera-Valencia, Valerio Leoni +7 more
2025Neurobiology of Disease3 citations Open access
Semantic Scholar
Commonly prescribed multi‐medication therapies exert sex‐specific effects on Alzheimer's disease pathology and metabolomic profiles in AppNL‐G‐F mice: Implications for personalized therapeutics in aging
Francesca Eroli, Kristina Johnell, Zeynep Acararicin, Christina Tsagkogianni +9 more
2025Alzheimer's & Dementia3 citations Open access
Semantic Scholar
Sex-dependent effects of CYP46A1 overexpression on cognitive function during aging
María Latorre-Leal, Patricia Rodriguez-Rodriguez, L. Franchini, M. Daniilidou +13 more
2021bioRxiv3 citations Open access
Semantic Scholar
Mouse PAW: reverse-translating the FINGER multimodal lifestyle intervention enhances synaptic plasticity and cognition in adult wild type female mice
Vilma Alanko, Francesca Eroli, Á. Végvári, A. Solomon +5 more
2024bioRxiv2 citations
Semantic Scholar
ERβ mediates sex-specific protection in the App-NL-G-F mouse model of Alzheimer’s disease
Aphrodite Demetriou, Birgitta Lindqvist, Heba G. Ali, Mohamed M. Shamekh +5 more
2024bioRxiv2 citations Open access
Semantic Scholar
Effects of gonadectomy on brain sex hormone levels and amyloid pathology in male and female App NL‐G‐F and App NL‐F mice
Patricia Munoz, Heba G. Ali, Aphrodite Demetriou, María Latorre-Leal +7 more
2026Journal of neuroendocrinology1 citations Open access
Semantic Scholar
Association of plasma fatty acid profile with trajectory of multimorbidity and mortality: A community-based longitudinal study.
Yang Li, Jiao Wang, Yu-Yang Miao, Michelle M. Dunk +4 more
2025The journals of gerontology. Series A, Biological sciences and medical sciences1 citations
Semantic Scholar
The Effects of CYP27A1 and CYP7B1 on cognitive function: two mouse models in Comparison
Julen Goikolea, María Latorre-Leal, Christina Tsagkogianni, Sonja Pikkupeura +6 more
20231 citations
Semantic Scholar
Prevention of Alzheimer’s by a Multimodal Lifestyle Protocol – Working‐mechanisms for Memory Gains: Mouse‐PAW
Vilma Alanko, Francesca Eroli, A. Solomon, T. Hartmann +4 more
2023Alzheimer's & Dementia1 citations Open access
Semantic Scholar
Neuron-derived Thioredoxin-80: a novel regulator of type-I interferon response in microglia
Julen Goikolea, Jean-Pierre Roussarie, G. Gereñu, Raul Loera-Valencia +4 more
2022bioRxiv1 citations Open access
Semantic Scholar
Reproductive lifespan and hormonal therapy in relation to later-life neurovascular health: A population-based study of women in the Gothenburg H70–1944 Birth Cohort
Giulia Lorenzon, Gemma García-Lluch, G. Coughlan, S. Sindi +11 more
2026medRxiv0 citations
Semantic Scholar
Renin‐Angiotensin System Inhibitor Use and Mortality in Older Hypertensive Patients With and Without Dementia: A Nationwide Registry‐Based Cohort Study
Marta Villa Lopez, M. Hoang, Hong Xu, Jakob Norgren +11 more
2026The Journal of Clinical Hypertension0 citations Open access
Semantic Scholar

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