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M. Kwok · SciRah

Researcher profile · Semantic Scholar

M. Kwok

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M. Kwok — researcher profile on SciRah

h-index: 13
Works: 41
Citations: 1,317

Most-cited papers

Monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia.
A. Rawstron, F. Bennett, S. O'Connor, M. Kwok +7 more
2008New England Journal of Medicine579 citations Open access
Semantic Scholar
ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells.
M. Kwok, N. Davies, A. Agathanggelou, E. Smith +11 more
2016Blood260 citations
Semantic Scholar
Minimal residual disease is an independent predictor for 10-year survival in CLL.
M. Kwok, A. Rawstron, A. Varghese, P. Evans +5 more
2016Blood129 citations Open access
Semantic Scholar
Synthetic lethality in chronic lymphocytic leukaemia with DNA damage response defects by targeting the ATR pathway.
M. Kwok, N. Davies, A. Agathanggelou, E. Smith +5 more
2015The Lancet77 citations
Semantic Scholar
USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status.
A. Agathanggelou, E. Smith, N. Davies, M. Kwok +19 more
2017Blood67 citations Open access
Semantic Scholar
Long-Term Ibrutinib Therapy Reverses CD8+ T Cell Exhaustion in B Cell Chronic Lymphocytic Leukaemia
H. Parry, N. Mirajkar, Natasha Cutmore, J. Zuo +11 more
2019Frontiers in Immunology40 citations Open access
Semantic Scholar
DNA damage response defects in hematologic malignancies: mechanistic insights and therapeutic strategies.
M. Kwok, A. Agathanggelou, T. Stankovic
2024Blood26 citations Open access
Semantic Scholar
Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL.
M. Kwok, C. Oldreive, A. Rawstron, Anshita Goel +26 more
2019Blood24 citations Open access
Semantic Scholar
Minimal Residual Disease Is a Predictor for Progression-Free and Overall Survival in Chronic Lymphocytic Leukemia (CLL) That Is Independent of the Type or Line of Therapy.
M. Kwok, A. Rawstron, A. Varghese, P. Hillmen
200919 citations
Semantic Scholar
Clonal Evolution of High-Risk Chronic Lymphocytic Leukemia: A Contemporary Perspective
M. Kwok, C. Wu
2021Frontiers in Oncology18 citations Open access
Semantic Scholar
Targeting the p53 Pathway in CLL: State of the Art and Future Perspectives
M. Kwok, A. Agathanggelou, N. Davies, T. Stankovic
2021Cancers16 citations Open access
Semantic Scholar
Tranexamic acid versus placebo to prevent bleeding in patients with haematological malignancies and severe thrombocytopenia (TREATT): a randomised, double-blind, parallel, phase 3 superiority trial.
L. Estcourt, Zoe K McQuilten, Peter Bardy, M. Cole-Sinclair +496 more
2024The Lancet Haematology15 citations Open access
Semantic Scholar
Dynamic changes in clonal cytogenetic architecture during progression of chronic lymphocytic leukemia in patients and patient-derived murine xenografts
N. Davies, M. Kwok, C. Gould, C. Oldreive +9 more
2017OncoTarget15 citations Open access
Semantic Scholar
Tracking rare single donor and recipient immune and leukemia cells after allogeneic hematopoietic cell transplantation using mitochondrial DNA mutations.
L. Penter, N. Cieri, K. Maurer, M. Kwok +17 more
2024Blood Cancer Discovery8 citations
Semantic Scholar
Cancer and COVID-19: On the Quest for Effective Vaccines.
M. Kwok, E. Fritsch, C. Wu
2020Cancer Discovery5 citations Open access
Semantic Scholar
Independent prognostic significance of minimal residual disease status in chronic lymphocytic leukaemia
M. Kwok, A. Rawstron, A. Varghese, P. Evans +5 more
20144 citations Open access
Semantic Scholar
Synthetic Lethality In CLL With DNA Damage Response Defect By Targeting ATR Pathway
T. Stankovic, D. Nicholas, M. Kwok, E. Smith +4 more
20134 citations
Semantic Scholar
Mutant ribosomal protein RPS15 drives B cell malignancy through oxidative stress and genomic instability
Catherine Gutierrez, M. Kwok, Neil G. Ruthen, Peyton Waddicor +40 more
2026Nature Communications2 citations Open access
Semantic Scholar
Impaired Response to Oxidative DNA Damage Underlies Genomic Instability in B-Cell Leukemia Driven By RPS15 Mutation
M. Kwok, Catherine Gutierrez, Neil G. Ruthen, Peyton Waddicor +20 more
2024Blood2 citations
Semantic Scholar
Ibrutinib: another string to its bow.
T. Stankovic, M. Kwok
2021Blood2 citations Open access
Semantic Scholar
PALB2 variant status in hematological malignancies – a potential therapeutic target?
C. Oldreive, P. Byrd, G. Stewart, Alexander J. Taylor +14 more
2019Leukemia and Lymphoma2 citations
Semantic Scholar
Targeting the Ataxia Telangiectasia and Rad3 Signaling Pathway to Overcome Chemoresistance in Cancer
M. Kwok, T. Stankovic
2019Targeting Cell Survival Pathways to Enhance Response to Chemotherapy2 citations
Semantic Scholar
Targeting therapeutic vulnerabilities in T-PLL.
M. Kwok, Tatjana Stankovic
2024Blood1 citations
Semantic Scholar
Genetics in the era of targeted CLL therapy.
T. Stankovic, M. Kwok
2020Blood1 citations Open access
Semantic Scholar
Targeting Replication Stress in Sporadic Tumours
M. Kwok, T. Stankovic
20181 citations
Semantic Scholar
ATR Inhibition Exacerbates Replication Stress in TP53 or ATM Deficient CLL Cells and Enhances Sensitivity to Chemotherapy and Targeted Therapy
M. Kwok, N. Davies, A. Agathanggelou, E. Smith +5 more
20141 citations
Semantic Scholar
Expanding the universe of T-PLL targets.
M. Kwok, Tatjana Stankovic
2025Blood0 citations
Semantic Scholar
Distinct archetypes of clonal dynamics underlie response and resistance to diverse CLL therapies
M. Kwok, Connor Johnson, E. Tausch, Liang Li +31 more
2025Blood0 citations
Semantic Scholar
Genome-scale clustered regularly interspaced short palindromic repeats screen identifies nucleotide metabolism as an actionable therapeutic vulnerability in diffuse large B-cell lymphoma
N. Davies, T. Francis, C. Oldreive, M. Azam +24 more
2024Haematologica0 citations Open access
Semantic Scholar
Leukemia Evolution and Resistance to Graft-Versus-Leukemia Responses Revealed By Mitochondrial DNA Mutations
L. Penter, N. Cieri, K. Maurer, M. Kwok +17 more
2024Blood0 citations
Semantic Scholar
CLL patients: GIVe me three!
M. Kwok, Tatjana Stankovic
2023Blood0 citations Open access
Semantic Scholar
Correction: Kwok et al. Targeting the p53 Pathway in CLL: State of the Art and Future Perspectives. Cancers 2021, 13, 4681
M. Kwok, A. Agathanggelou, N. Davies, T. Stankovic
2022Cancers0 citations Open access
Semantic Scholar
Linking epigenome regulation with DNA repair.
T. Stankovic, M. Kwok
2022Blood0 citations
Semantic Scholar
The three musketeers: uniting against CLL.
M. Kwok, T. Stankovic
2022Blood0 citations Open access
Semantic Scholar
University of Birmingham Clonal evolution of high-risk chronic lymphocytic leukemia
M. Kwok, C. Kuang, Catherine J. Wu, Kwok Wu
20210 citations
Semantic Scholar
Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL Running Title: Natural history and mechanism of spontaneous CLL regression
M. Kwok, C. Oldreive, A. Rawstron, Anshita Goel +31 more
20210 citations
Semantic Scholar
Novel insights into the clinical heterogeneity and treatment of chronic lymphocytic leukaemia
M. Kwok
20180 citations
Semantic Scholar
USP 7 inhibition alters homologous recombination repair and targets CLL cells independent of ATM / p 53 functional status Running title : USP 7 INHIBITION TARGETS ATM AND P 53 DEFECTIVE CLL
A. Agathanggelou, E. Smith, N. Davies, M. Kwok +21 more
20170 citations
Semantic Scholar
Kinetics of CLL Subclonal Architecture: Spontaneous Disease Progression or Treatment-Induced Selection?
C. Oldreive, N. Davies, A. Skowrońska, M. Kwok +6 more
20150 citations
Semantic Scholar
CLL Progression Is Associated with Increased Clonal Diversity and Replication Stress
A. Agathanggelou, A. Skowrońska, N. Davies, M. Kwok +4 more
20140 citations
Semantic Scholar
Monoclonal B-Cell Lymphocytosis (MBL) Is a Precursor State for Chronic Lymphocytic Leukemia (CLL) with 1% Progression Per Year.
A. Rawstron, Fiona L. Bennet, S. O'Connor, M. Kwok +7 more
20070 citations
Semantic Scholar

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