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C. Chaussade · SciRah

Researcher profile · Semantic Scholar

C. Chaussade

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C. Chaussade — researcher profile on SciRah

h-index: 22
Works: 35
Citations: 1,605

Most-cited papers

Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling.
C. Chaussade, G. Rewcastle, Jackie D. Kendall, W. Denny +7 more
2007Biochemical Journal219 citations Open access
Semantic Scholar
Production of Phosphatidylinositol 5-Phosphate by the Phosphoinositide 3-Phosphatase Myotubularin in Mammalian Cells*
H. Tronchere, J. Laporte, C. Pendaries, C. Chaussade +4 more
2004Journal of Biological Chemistry151 citations Open access
Semantic Scholar
The level of AKT phosphorylation on threonine 308 but not on serine 473 is associated with high-risk cytogenetics and predicts poor overall survival in acute myeloid leukaemia
N. Gallay, C. Dos Santos, L. Cuzin, M. Bousquet +6 more
2009Leukemia130 citations Open access
Semantic Scholar
Phosphoinositide 3-Kinase-mediated Reduction of Insulin Receptor Substrate-1/2 Protein Expression via Different Mechanisms Contributes to the Insulin-induced Desensitization of Its Signaling Pathways in L6 Muscle Cells*
L. Pirola, S. Bonnafous, A. M. Johnston, C. Chaussade +2 more
2003Journal of Biological Chemistry118 citations Open access
Semantic Scholar
Atypical antipsychotic drugs induce derangements in glucose homeostasis by acutely increasing glucagon secretion and hepatic glucose output in the rat
Greg C. Smith, C. Chaussade, M. Vickers, J. Jensen +1 more
2008Diabetologia92 citations Open access
Semantic Scholar
Syndecan-2 is a novel ligand for the protein tyrosine phosphatase receptor CD148
J. Whiteford, Xiaojie Xian, C. Chaussade, B. Vanhaesebroeck +2 more
2011Molecular Biology of the Cell87 citations Open access
Semantic Scholar
Expression of myotubularin by an adenoviral vector demonstrates its function as a phosphatidylinositol 3-phosphate [PtdIns(3)P] phosphatase in muscle cell lines: involvement of PtdIns(3)P in insulin-stimulated glucose transport.
C. Chaussade, L. Pirola, S. Bonnafous, F. Blondeau +7 more
2003Molecular Endocrinology81 citations Open access
Semantic Scholar
Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity
Samira Alliouachene, B. Bilanges, G. Chicanne, Karen E. Anderson +13 more
2015Cell Reports75 citations Open access
Semantic Scholar
Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism
B. Bilanges, Samira Alliouachene, Wayne Pearce, D. Morelli +24 more
2017Nature Communications74 citations Open access
Semantic Scholar
Essential role of class II PI3K-C2α in platelet membrane morphology.
C. Valet, G. Chicanne, C. Séverac, C. Chaussade +7 more
2015Blood55 citations Open access
Semantic Scholar
Patent foramen ovale and stroke in intermediate-risk pulmonary embolism.
D. Doyen, M. Castellani, P. Moceri, O. Chiche +5 more
2014Chest55 citations
Semantic Scholar
Functional differences between two classes of oncogenic mutation in the PIK3CA gene.
C. Chaussade, K. Cho, C. Mawson, G. Rewcastle +1 more
2009Biochemical and Biophysical Research Communications - BBRC54 citations Open access
Semantic Scholar
Synthesis, biological evaluation and molecular modelling of sulfonohydrazides as selective PI3K p110α inhibitors
Jackie D. Kendall, G. Rewcastle, R. Frédérick, C. Mawson +6 more
200747 citations Open access
Semantic Scholar
Imaging in pulmonary hypertension: Focus on the role of echocardiography.
P. Moceri, D. Baudouy, O. Chiche, P. Cerboni +3 more
2014Archives of Cardiovascular Diseases43 citations Open access
Semantic Scholar
Both p110α and p110β Isoforms of Phosphatidylinositol 3‐OH‐Kinase are Required for Insulin Signalling in the Hypothalamus
A. Tups, G. Anderson, M. Z. Rizwan, R. A. Augustine +3 more
2010Journal of neuroendocrinology42 citations
Semantic Scholar
Nuclear forkhead box O1 controls and integrates key signaling pathways in hepatocytes.
Mourad Naïmi, N. Gautier, C. Chaussade, Á. M. Valverde +2 more
2007Endocrinology41 citations Open access
Semantic Scholar
Calpain interacts with class IA phosphoinositide 3-kinases regulating their stability and signaling activity
Luisa Beltran, C. Chaussade, B. Vanhaesebroeck, P. Cutillas
2011Proceedings of the National Academy of Sciences of the United States of America38 citations Open access
Semantic Scholar
Phosphoinositide-3-kinase (PI3K) inhibitors: identification of new scaffolds using virtual screening.
R. Frédérick, C. Mawson, Jackie D. Kendall, C. Chaussade +3 more
2009Bioorganic & Medicinal Chemistry Letters32 citations Open access
Semantic Scholar
Novel pyrazolo[1,5-a]pyridines as p110α-selective PI3 kinase inhibitors: Exploring the benzenesulfonohydrazide SAR.
Jackie D. Kendall, A. Giddens, Kit-Yee Tsang, R. Frédérick +16 more
2012Bioorganic & Medicinal Chemistry31 citations Open access
Semantic Scholar
Inactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice
Samira Alliouachene, B. Bilanges, C. Chaussade, Wayne Pearce +4 more
2016Diabetologia30 citations Open access
Semantic Scholar
Discovery of pyrazolo[1,5-a]pyridines as p110α-selective PI3 kinase inhibitors.
Jackie D. Kendall, Patrick D. O'Connor, A. J. Marshall, R. Frédérick +15 more
2012Bioorganic & Medicinal Chemistry25 citations Open access
Semantic Scholar
Cardiac biomarkers in Takotsubo cardiomyopathy.
D. Doyen, P. Moceri, O. Chiche, E. Schouver +4 more
2014International Journal of Cardiology23 citations
Semantic Scholar
Investigating the role of class-IA PI 3-kinase isoforms in adipocyte differentiation.
J. E. Kim, P. Shepherd, C. Chaussade
2009Biochemical and Biophysical Research Communications - BBRC17 citations
Semantic Scholar
d-chiro-Inositol Attenuates Epinephrine-stimulated Hepatic Glucose Output in the Isolated Perfused Liver Independently of Insulin
Lynda Whiting, R. N. Danaher, K. Ruggiero, C. C. Lee +4 more
2012Hormone and Metabolic Research13 citations
Semantic Scholar
Evidence for a role for the p110-alpha isoform of PI3K in skeletal function.
A. Grey, C. Chaussade, Victoria G. Empson, Jian-ming Lin +6 more
2010Biochemical and Biophysical Research Communications - BBRC11 citations
Semantic Scholar
Novel pyrazolo[1,5-a]pyridines with improved aqueous solubility as p110α-selective PI3 kinase inhibitors.
Jackie D. Kendall, A. Giddens, Kit-Yee Tsang, E. Marshall +13 more
2017Bioorganic & Medicinal Chemistry Letters8 citations Open access
Semantic Scholar
Novel pyrazolo[1,5-a]pyridines as PI3K inhibitors: variation of the central linker group
Jackie D. Kendall, A. J. Marshall, A. Giddens, Kit-Yee Tsang +15 more
20147 citations
Semantic Scholar
Synthesis, biological evaluation and molecular modelling of sulfonohydrazides as selective PI3K p110alpha inhibitors.
Jackie D. Kendall, G. Rewcastle, R. Frédérick, C. Mawson +6 more
2007Bioorganic & Medicinal Chemistry5 citations
Semantic Scholar
The Level of AKT Phosphorylation on Threonine 308 but Not on Serine 473 Is Associated with High-Risk Cytogenetics and Predicts Poor Overall Survival in Acute Myeloid Leukemia.
N. Gallay, C. Dos Santos, L. Cuzin, M. Bousquet +6 more
20082 citations
Semantic Scholar
LB1578 Identification and characterization of highly optimized RORγ inverse agonists for the topical treatment of psoriasis
C. Hervouet, F. Bihl, G. Ouvry, B. Musicki +10 more
2018Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
431 Live demodex mites modulate the inflammatory responses of sebocytes and PBMCs
S. Gatault, R. Foley, C. Chaussade, L. Shiels +2 more
20170 citations Open access
Semantic Scholar
348 Topical RORγ inverse agonist alleviate preclinical models of psoriasis
C. Hervouet, F. Bihl, G. Ouvry, C. Bouix-Peter +6 more
20170 citations Open access
Semantic Scholar
P0300 - Second generation antipsychotic medications induce type 2 diabete like syndrome by increasing hepatic glucose output and subsequently insulin secretion: Implications for mechanism of drug action
Greg C. Smith, C. Chaussade, Mark H. Vickers, Peter R. Shepherd
2008European psychiatry0 citations
Semantic Scholar
Using a signalomics approach to dissect the true cellular effects of kinase inhibitors
Je Kim, E. Leung, C. Chaussade, J. Simpson +1 more
20070 citations
Semantic Scholar
P 0299 Atypical antipsychotics and their metabolic impact on psychiatrically hospitalized children and adolescents
R. R, Silva, M., Ghaffari +10 more
0 citations
Semantic Scholar

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