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E. Pong · SciRah

Researcher profile · Semantic Scholar

E. Pong

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E. Pong — researcher profile on SciRah

h-index: 17
Works: 34
Citations: 1,419

Most-cited papers

Potent in vitro and in vivo activity of an Fc-engineered anti-CD19 monoclonal antibody against lymphoma and leukemia.
H. Horton, M. Bernett, E. Pong, M. Peipp +8 more
2008Cancer Research267 citations
Semantic Scholar
Inhibition of B cell receptor-mediated activation of primary human B cells by coengagement of CD19 and FcgammaRIIb with Fc-engineered antibodies.
S. Chu, I. Voštiar, S. Karki, Gregory L. Moore +5 more
2008Molecular Immunology158 citations
Semantic Scholar
Antibody-Mediated Coengagement of FcγRIIb and B Cell Receptor Complex Suppresses Humoral Immunity in Systemic Lupus Erythematosus
H. Horton, S. Chu, E. Ortiz, E. Pong +7 more
2011Journal of Immunology147 citations Open access
Semantic Scholar
A novel bispecific antibody format enables simultaneous bivalent and monovalent co-engagement of distinct target antigens
Gregory L. Moore, C. Bautista, E. Pong, Duc-Hanh T. Nguyen +6 more
2011mAbs111 citations Open access
Semantic Scholar
Methylation in hMLH1 promoter interferes with its binding to transcription factor CBF and inhibits gene expression
G. Deng, Ada Chen, E. Pong, Y. Kim
2001Oncogene100 citations
Semantic Scholar
Reduction of total IgE by targeted coengagement of IgE B-cell receptor and FcγRIIb with Fc-engineered antibody.
S. Chu, H. Horton, E. Pong, Irene Leung +8 more
2012Journal of Allergy and Clinical Immunology92 citations
Semantic Scholar
Fc-engineered anti-CD40 antibody enhances multiple effector functions and exhibits potent in vitro and in vivo antitumor activity against hematologic malignancies.
H. Horton, M. Bernett, M. Peipp, E. Pong +7 more
2010Blood75 citations Open access
Semantic Scholar
Promoter methylation inhibits APC gene expression by causing changes in chromatin conformation and interfering with the binding of transcription factor CCAAT-binding factor.
G. Deng, G. Song, E. Pong, M. Sleisenger +1 more
2004Cancer Research71 citations
Semantic Scholar
A robust heterodimeric Fc platform engineered for efficient development of bispecific antibodies of multiple formats.
Gregory L. Moore, M. Bernett, R. Rashid, E. Pong +8 more
2019Methods70 citations Open access
Semantic Scholar
Suppression of Rheumatoid Arthritis B Cells by XmAb5871, an Anti‐CD19 Antibody That Coengages B Cell Antigen Receptor Complex and Fcγ Receptor IIb Inhibitory Receptor
S. Chu, K. Yeter, Roshan Kotha, E. Pong +9 more
2013Arthritis & Rheumatology58 citations
Semantic Scholar
Engineering fully human monoclonal antibodies from murine variable regions.
M. Bernett, S. Karki, Gregory L. Moore, Irene Leung +8 more
2010Journal of Molecular Biology51 citations
Semantic Scholar
Potent in vitro and in vivo activity of an Fc-engineered humanized anti-HM1.24 antibody against multiple myeloma via augmented effector function.
Yu-Tzu Tai, H. Horton, Sun-Young Kong, E. Pong +11 more
2012Blood47 citations Open access
Semantic Scholar
Immunotherapy with Long-Lived Anti-CD123 × Anti-CD3 Bispecific Antibodies Stimulates Potent T Cell-Mediated Killing of Human AML Cell Lines and of CD123+ Cells in Monkeys: A Potential Therapy for Acute Myelogenous Leukemia
S. Chu, E. Pong, Hsing Chen, Sheryl Phung +10 more
201441 citations
Semantic Scholar
Tuning T Cell Affinity Improves Efficacy and Safety of Anti-CD38 × Anti-CD3 Bispecific Antibodies in Monkeys - a Potential Therapy for Multiple Myeloma
Gregory L. Moore, Sung‐Hyung Lee, Suzanne Schubbert, Yvonne Miranda +14 more
201531 citations
Semantic Scholar
Immune suppression in cynomolgus monkeys by XPro9523
M. Bernett, S. Chu, Irene Leung, Gregory L. Moore +9 more
2013mAbs28 citations Open access
Semantic Scholar
Inhibition of B cell activation following in vivo co-engagement of B cell antigen receptor and Fcγ receptor IIb in non-autoimmune-prone and SLE-prone mice
S. Chu, E. Pong, Christine Bonzon, N. Yu +5 more
2020Journal of Translational Autoimmunity23 citations Open access
Semantic Scholar
Immunotherapy with Long-Lived Anti-CD38 × Anti-CD3 Bispecific Antibodies Stimulates Potent T Cell-Mediated Killing of Human Myeloma Cell Lines and CD38+ Cells in Monkeys: A Potential Therapy for Multiple Myeloma
S. Chu, Yvonne Miranda, Sheryl Phung, Hsing Chen +11 more
201418 citations Open access
Semantic Scholar
Immunotherapy with Long-Lived Anti-CD20 × Anti-CD3 Bispecific Antibodies Stimulates Potent T Cell-Mediated Killing of Human B Cell Lines and of Circulating and Lymphoid B Cells in Monkeys: A Potential Therapy for B Cell Lymphomas and Leukemias
S. Chu, Sung‐Hyung Lee, R. Rashid, Hsing Chen +12 more
201416 citations
Semantic Scholar
Accelerated clearance and degradation of cell free HIV by neutralizing antibodies occurs via FcγRIIb on liver sinusoidal endothelial cells by endocytosis
James M. Turman, Alana M. Cheplowitz, Charu Tiwari, Thushara Thomas +15 more
2021Journal of Immunology9 citations Open access
Semantic Scholar
1067 Synergistic combination of natural killer cell engagers (NKEs) with proinflammatory cytokines
Tian Zhang, Matthew S Faber, E. Pong, Ke Liu +10 more
2022Regular and Young Investigator Award Abstracts2 citations Open access
Semantic Scholar
An Fc-Engineered Humanized Anti-CD40 Monoclonal Antibody, XmAb5485, Exhibits Potent Activity in Vitro and in Vivo against Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia and Multiple Myeloma
E. Zhukovsky, H. Horton, M. Peipp, E. Pong +6 more
20082 citations
Semantic Scholar
Abstract 5663: Affinity tuned XmAb®2+1 PSMA x CD3 bispecific antibodies demonstrate selective activity in prostate cancer models
Alex Nisthal, M. Dragovich, E. Pong, Veronica G Zeng +9 more
2020Immunology1 citations
Semantic Scholar
Abstract 5000: Immunotherapy with anti-PSMA x anti-CD3 bispecific antibody stimulates potent killing of a human prostate cancer cell line and target-mediated T cell activation in monkeys: A potential therapy for prostate cancer
S. Chu, E. Pong, R. Rashid, Hsing Chen +11 more
20161 citations
Semantic Scholar
1193 Synergistic targeting of multiple activating pathways with natural killer cell engagers
Tian Zhang, Matthew S Faber, E. Pong, Ke Liu +14 more
2023Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
872 PD1 x TGFbR2 and CD5 x TGFbR2 bispecifics selectively block TGFbR2 on target-positive T cells, promote T cell activation, and elicit an anti-tumor response in solid tumors
Gregory L. Moore, Suzanne Schubbert, Christine Bonzon, K. Avery +7 more
2021Journal for ImmunoTherapy of Cancer0 citations Open access
Semantic Scholar
714 PD1 x TGFβR2 bispecifics selectively block TGFβR2 on PD1-positive T cells, promote T cell activation, and elicit an anti-tumor response in solid tumors
G. Moore, Suzanne Schubbert, Christine Bonzon, K. Avery +7 more
20200 citations Open access
Semantic Scholar
hematologic malignancies and exhibits potent in vitro and in vivo antitumor activity against Fc-engineered anti-CD40 antibody enhances multiple effector functions
Hsing Chen, R. Repp, J. Desjarlais, E. Zhukovsky +7 more
20120 citations
Semantic Scholar
Suppresses Humoral Immunity in Systemic RIIb and B Cell Receptor Complex g Antibody-Mediated Coengagement of Fc
H. Horton, S. Chu, E. Ortiz, E. Pong +7 more
20110 citations
Semantic Scholar
This information is current as Lupus Erythematosus Suppresses Humoral Immunity in Systemic RIIb and B Cell Receptor Complex γ Antibody-Mediated Coengagement of Fc
H. Horton, S. Chu, E. Ortiz, E. Pong +7 more
20110 citations
Semantic Scholar
Inhibition of B Cell Receptor-Mediated B Cell Activation and IgE secretion by Coengagement of Surface IgE and FcγRIIb with Fc-Engineered Antibodies
David Edmund Szymkowski, H. Horton, S. Chu, J. Zalevsky +3 more
20100 citations
Semantic Scholar
Xmab™ Fc-engineered anti-cd19 monoclonal antibodies with in vitro and in vivo efficacy against lymphoma and leukemia
E. Zhukovsky, M. Bernett, S. Chu, S. Karki +7 more
20080 citations
Semantic Scholar
Optimized antibodies directed against CD19
M. Bernett, S. Chu, J. Desjarlais, S. Karki +4 more
20070 citations
Semantic Scholar
XmAb™ Fc Engineered Anti-CD19 Monoclonal Antibody with Enhanced In Vitro Efficacy Against Lymphoma and Leukemia.
E. Zhukovsky, S. Chu, M. Bernett, S. Karki +5 more
20070 citations
Semantic Scholar
CCAAT-Binding Factor Interfering with the Binding of Transcription Factor Causing Changes in Chromatin Conformation and Gene Expression by APC Promoter Methylation Inhibits
G. Deng, G. Song, E. Pong, M. Sleisenger +1 more
20040 citations
Semantic Scholar

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