Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

P. Buch · SciRah

Researcher profile · Semantic Scholar

P. Buch

Share profile

P. Buch — researcher profile on SciRah

h-index: 12
Works: 31
Citations: 1,244

Most-cited papers

Effective gene therapy with nonintegrating lentiviral vectors
Rafael J. Yáñez-Muñoz, K. Balaggan, A. Macneil, S. Howe +13 more
2006Nature Medicine486 citations
Semantic Scholar
Gene replacement therapy rescues photoreceptor degeneration in a murine model of Leber congenital amaurosis lacking RPGRIP.
B. Pawlyk, Alexander J. Smith, P. Buch, M. Adamian +4 more
2005Investigative Ophthalmology and Visual Science132 citations Open access
Semantic Scholar
AAV-mediated gene therapy for retinal disorders: from mouse to man
P. Buch, James W. B. Bainbridge, R. Ali
2008Gene Therapy130 citations Open access
Semantic Scholar
In contrast to AAV-mediated Cntf expression, AAV-mediated Gdnf expression enhances gene replacement therapy in rodent models of retinal degeneration.
P. Buch, R. MacLaren, Y. Durán, K. Balaggan +4 more
2006Molecular Therapy104 citations Open access
Semantic Scholar
Long-Term Preservation of Cones and Improvement in Visual Function Following Gene Therapy in a Mouse Model of Leber Congenital Amaurosis Caused by Guanylate Cyclase-1 Deficiency
M. Mihelec, R. Pearson, S. Robbie, P. Buch +4 more
2011Human Gene Therapy72 citations Open access
Semantic Scholar
Guanylate cyclases and associated activator proteins in retinal disease
D. Hunt, P. Buch, M. Michaelides
2009Molecular and Cellular Biochemistry71 citations
Semantic Scholar
Local administration of an adeno-associated viral vector expressing IL-10 reduces monocyte infiltration and subsequent photoreceptor damage during experimental autoimmune uveitis.
C. Broderick, Alexander J. Smith, K. Balaggan, A. Georgiadis +7 more
2005Molecular Therapy62 citations Open access
Semantic Scholar
Subretinal delivery of adeno-associated virus serotype 2 results in minimal immune responses that allow repeat vector administration in immunocompetent mice
S. E. Barker, C. Broderick, S. Robbie, Y. Durán +7 more
2009Journal of Gene Medicine55 citations Open access
Semantic Scholar
Dominant Cone-Rod Dystrophy: A Mouse Model Generated by Gene Targeting of the GCAP1/Guca1a Gene
P. Buch, M. Mihelec, P. Cottrill, S. Wilkie +6 more
2011PLoS ONE41 citations Open access
Semantic Scholar
CNTF gene transfer protects ganglion cells in rat retinae undergoing focal injury and branch vessel occlusion.
R. MacLaren, P. Buch, Alexander J. Smith, K. Balaggan +4 more
2006Experimental Eye Research41 citations
Semantic Scholar
Neuroprotective gene therapy for the treatment of inherited retinal degeneration.
P. Buch, R. MacLaren, R. Ali
2007Current Gene Therapy27 citations
Semantic Scholar
Absence of ocular malignant transformation after sub-retinal delivery of rAAV2/2 or integrating lentiviral vectors in p53-deficient mice
K. Balaggan, Y. Durán, A. Georgiadis, C. Thaung +7 more
2011Gene Therapy15 citations Open access
Semantic Scholar
Replacement Gene Therapy Rescues Photoreceptor Degeneration in a Murine Model of Leber Congenital Amaurosis (LCA) Lacking RPGRIP
B. Pawlyk, Alexander J. Smith, P. Buch, M. Adamian +4 more
20053 citations
Semantic Scholar
Absence Of Ocular Malignant Transformation After Subretinal Delivery Of Raav2/2 Or Hiv-1 Vectors In P53 Knockout Mice
K. Balaggan, Y. Durán, P. Buch, A. Macneil +6 more
20111 citations
Semantic Scholar
A novel ‘knock-in’mouse model for cone dystrophy: a point mutation in guca1a causes a loss of cone-mediated retinal function and photoreceptor degeneration
P. Buch, P. Cottrill, S. Wilkie, R. Pearson +6 more
20081 citations
Semantic Scholar
Specific Evaluation of the Oncogenic Potential of Aav2/2 Vectors After Intraocular Delivery in P53 Knockout Mice
K. Balaggan, Y. Durán, P. Buch, A. Macneil +4 more
20071 citations
Semantic Scholar
Corrigendum to "Local Administration of an Adeno-Associated Viral Vector Expressing IL-10 Reduces Monocyte Infiltration and Subsequent Photoreceptor Damage During Experimental Autoimmune Uveitis".
C. Broderick, Alexander J. Smith, K. Balaggan, A. Georgiadis +7 more
2006Molecular Therapy1 citations Open access
Semantic Scholar
AAV–Mediated GDNF Expression in Combination With Gene Replacement Therapy to Treat Rodent Models of Retinal Degeneration
P. Buch, K. Balaggan, Y. Durán, Alexander J. Smith +2 more
20051 citations
Semantic Scholar
Gene therapy leads to long term improvement of retinal function in the heterozygous retinal degeneration slow mouse (rds(
F. Schlichtenbrede, M. Tschernutter, J. Bainbridge, P. Buch +3 more
20041 citations
Semantic Scholar
Non-Integrating Lentiviral Gene Transfer of E2F2 to Induce Corneal Endothelial Cell Replication
D. Kampik, Alexander J. Smith, Ufo Luhmann, P. Buch +2 more
20100 citations
Semantic Scholar
Improved Cone Function Following Gene Therapy in a Mouse Model of Leber Congenital Amaurosis (LCA) Caused by RetGC Deficiency
M. Mihelec, P. Buch, S. Robbie, Alexander J. Smith +3 more
20100 citations
Semantic Scholar
Gene Therapy in the RetGC Mouse Model of Dominant Cone-Rod Dystrophy
M. Mihelec, P. Buch, Alexander J. Smith, J. Bainbridge +2 more
20090 citations
Semantic Scholar
Pseudotyped adeno-associated viral vectors to enhance gene replacement therapy in a mouse model of retinal degeneration
P. Buch, J. McIntosh, A. Georgiadis, F. Mowat +4 more
20080 citations
Semantic Scholar
Mice Heterozygous for a Glu155Gly Gene Targeted Mutation in GCAP1 Lack Flicker Response and Show Severely Reduced Photopic ERG Amplitudes
P. Buch, P. Cottrill, S. Wilkie, R. Pearson +3 more
20070 citations
Semantic Scholar
Assessment of Longterm Neuroprotection by CNTF Gene Transfer in a Mouse Inherited Retinal Degeneration
R. MacLaren, P. Buch, A. Georgiadis, M. Tschernutter +3 more
20070 citations
Semantic Scholar
Comparative Analysis of Neural Stem Cells Isolated From the Iris, Pars Plana and Ciliary Body of the Porcine Eye
A. Macneil, R. Pearson, R. MacLaren, P. Buch +3 more
20070 citations
Semantic Scholar
Development of gene therapy strategies in rodent models of retinal degeneration.
P. Buch
20070 citations
Semantic Scholar
Minimal Immune Responses Following Subretinal Delivery of AAV2 Demonstrate Safety, Efficacy and Allow Long-Term Transgene Expression in C57Bl/6 and RPE65-/- Mice
S. E. Barker, C. Broderick, Y. Durán, M. Natkunarajah +5 more
20070 citations
Semantic Scholar
Non–Integrating Lentiviral Vectors for Ocular Gene Transfer
K. Balaggan, R. Yanez, A. Macneil, Alexander J. Smith +6 more
20060 citations
Semantic Scholar
391. Effective Gene Therapy with Non-Integrating Lentivirus Vectors
Rafael J. Yáñez-Muñoz, K. Balaggan, A. Macneil, Alexander J. Smith +8 more
20050 citations Open access
Semantic Scholar
Intraretinal Regeneration of Axotomised Retinal Ganglion Cells After AAV Mediated CNTF Delivery
R. Ali, R. MacLaren, P. Buch, K. Balaggan +2 more
20050 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

R. Ali×28
Invite
R. Ali — researcher profile on SciRah
Alexander J. Smith×17
Invite
Alexander J. Smith — researcher profile on SciRah
K. Balaggan×14
Invite
K. Balaggan — researcher profile on SciRah
Y. Durán×11
Invite
Y. Durán — researcher profile on SciRah

×10

Invite

R. MacLaren — researcher profile on SciRah

Invite

A. Macneil — researcher profile on SciRah

S. E. Barker×7

Invite

S. E. Barker — researcher profile on SciRah

J. Bainbridge×7

Invite

J. Bainbridge — researcher profile on SciRah

A. Georgiadis×7

Invite

A. Georgiadis — researcher profile on SciRah

Invite

R. Pearson — researcher profile on SciRah

Invite

D. Hunt — researcher profile on SciRah

Invite

A. Thrasher — researcher profile on SciRah