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A. West · SciRah

Researcher profile · Semantic Scholar

A. West

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A. West — researcher profile on SciRah

h-index: 18
Works: 34
Citations: 2,639

Most-cited papers

New and emerging HDAC inhibitors for cancer treatment.
A. West, R. Johnstone
2014Journal of Clinical Investigation1,310 citations Open access
Semantic Scholar
Radiotherapy increases the permissiveness of established mammary tumors to rejection by immunomodulatory antibodies.
I. Verbrugge, J. Hagekyriakou, L. Sharp, M. Gallí +7 more
2012Cancer Research276 citations
Semantic Scholar
An intact immune system is required for the anticancer activities of histone deacetylase inhibitors.
A. West, S. Mattarollo, J. Shortt, L. Cluse +3 more
2013Cancer Research120 citations Open access
Semantic Scholar
Oncolytic virus and anti-4-1BB combination therapy elicits strong antitumor immunity against established cancer.
Liza B. John, Linda J. Howland, Jacqueline K. Flynn, A. West +9 more
2012Cancer Research110 citations
Semantic Scholar
Eradication of solid tumors using histone deacetylase inhibitors combined with immune-stimulating antibodies
A. Christiansen, A. West, K. Banks, N. Haynes +3 more
2011Proceedings of the National Academy of Sciences of the United States of America107 citations Open access
Semantic Scholar
NKT cell adjuvant-based tumor vaccine for treatment of myc oncogene-driven mouse B-cell lymphoma.
S. Mattarollo, A. West, Kim Steegh, Helene Duret +11 more
2012Blood78 citations Open access
Semantic Scholar
The anticancer effects of HDAC inhibitors require the immune system
A. West, M. Smyth, R. Johnstone
2014Oncoimmunology73 citations Open access
Semantic Scholar
Identification of a TLR2-regulated gene signature associated with tumor cell growth in gastric cancer
A. West, K. Tang, H. Tye, L. Yu +14 more
2017Oncogene69 citations
Semantic Scholar
Toll‐like receptor 2 regulates metabolic reprogramming in gastric cancer via superoxide dismutase 2
You-Dong Liu, Liang Yu, L. Ying, J. Balic +9 more
2019International Journal of Cancer66 citations Open access
Semantic Scholar
Inflammasome Adaptor ASC Suppresses Apoptosis of Gastric Cancer Cells by an IL18-Mediated Inflammation-Independent Mechanism.
Virginie Deswaerte, Paul M. Nguyen, A. West, Alison F Browning +15 more
2018Cancer Research65 citations Open access
Semantic Scholar
Hyperactive gp130/STAT3‐driven gastric tumourigenesis promotes submucosal tertiary lymphoid structure development
David G. Hill, Liang Yu, Hugh Gao, J. Balic +11 more
2018International Journal of Cancer60 citations Open access
Semantic Scholar
STAT3-mediated upregulation of the AIM2 DNA sensor links innate immunity with cell migration to promote epithelial tumourigenesis
Ruby E. Dawson, Virginie Deswaerte, A. West, K. Tang +15 more
2021Gut36 citations
Semantic Scholar
Regulation of the ITGA2 gene by epigenetic mechanisms in prostate cancer
S. P. Chin, J. Marthick, A. West, Annabel K. Short +5 more
2015The Prostate36 citations Open access
Semantic Scholar
Blockade of the protease ADAM17 ameliorates experimental pancreatitis
M. Saad, Teresa Weng, Joanne Lundy, L. Gearing +9 more
2022Proceedings of the National Academy of Sciences of the United States of America29 citations Open access
Semantic Scholar
Serine-phosphorylated STAT3 promotes tumorigenesis via modulation of RNA polymerase transcriptional activity.
J. Balic, Daniel J. Garama, M. Saad, Liang Yu +6 more
2019Cancer Research29 citations Open access
Semantic Scholar
Constitutive STAT3 serine phosphorylation promotes Helicobacter-mediated gastric disease.
J. Balic, M. Saad, Ruby E. Dawson, Alice J. West +10 more
2020American Journal of Pathology25 citations Open access
Semantic Scholar
Inflammatory and non-inflammatory roles for Toll-like receptors in gastrointestinal cancer.
A. West, B. Jenkins
2015Current pharmaceutical design23 citations Open access
Semantic Scholar
Transcriptional and epigenetic regulation of the GM-CSF promoter by RUNX1.
P. C. Oakford, S. James, Abeer A. Qadi, A. West +4 more
2010Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis23 citations Open access
Semantic Scholar
Toll-like Receptor 9 Promotes Initiation of Gastric Tumorigenesis by Augmenting Inflammation and Cellular Proliferation
Kei-shuen. Tang, L. McLeod, Thaleia Livis, A. West +10 more
2022Cellular and Molecular Gastroenterology and Hepatology18 citations Open access
Semantic Scholar
TLR2 activation promotes tumour growth and associates with patient survival and chemotherapy response in pancreatic ductal adenocarcinoma
Joanne Lundy, L. Gearing, Hugh Gao, A. West +8 more
2021Oncogene17 citations
Semantic Scholar
The cytosolic DNA sensor AIM2 promotes Helicobacter‐induced gastric pathology via the inflammasome
Ruby E. Dawson, Virginie Deswaerte, A. West, Ekimei Sun +7 more
2023Immunology and Cell Biology16 citations Open access
Semantic Scholar
The Leukemia Inhibitory Factor Receptor Gene Is a Direct Target of RUNX1
Abeer A. Qadi, P. Taberlay, J. L. Phillips, A. Young +4 more
2016Journal of Cellular Biochemistry13 citations Open access
Semantic Scholar
The combination of histone deacetylase inhibitors with immune-stimulating antibodies has potent anti-cancer effects
A. West, A. Christiansen, M. Smyth, R. Johnstone
2012Oncoimmunology12 citations Open access
Semantic Scholar
Oncogenic dependency on STAT3 serine phosphorylation in KRAS mutant lung cancer
Sultan Alhayyani, L. McLeod, A. West, J. Balic +9 more
2021Oncogene11 citations
Semantic Scholar
Inflammasome-Associated Gastric Tumorigenesis Is Independent of the NLRP3 Pattern Recognition Receptor
Alice J. West, Virginie Deswaerte, A. West, L. Gearing +2 more
2022Frontiers in Oncology10 citations Open access
Semantic Scholar
Naturally derived cytokine peptides limit virus replication and severe disease during influenza A virus infection
Christopher M. Harpur, A. West, M. Le Page, M. Lam +4 more
2023Clinical & Translational Immunology8 citations Open access
Semantic Scholar
Investigating the Role of Toll-Like Receptors in Mouse Models of Gastric Cancer.
A. West, B. Jenkins
2016Methods in molecular biology3 citations
Semantic Scholar
Abstract 1462: Non-inflammatory role of ASC-dependent inflammasomes in promoting gastric tumourigenesis via IL-18
B. Jenkins, Virginie Deswaerte, A. West, Paul M. Nguyen +1 more
20160 citations
Semantic Scholar
18: The inflammasome adaptor ASC mediates gastric tumourigenesis independent of inflammation
Alison F Browning, A. West, Daniel Croagh, B. Jenkins
20140 citations
Semantic Scholar
Therapeutics , Targets , and Chemical Biology An Intact Immune System Is Required for the Anticancer Activities of Histone Deacetylase Inhibitors
A. West, S. Mattarollo, J. Shortt, L. Cluse +3 more
20130 citations
Semantic Scholar
oncogene-driven mouse B cell lymphoma myc NKT cell adjuvant-based tumor vaccine for treatment of
W. Löwe, R. Johnstone, M. Smyth, G. Matthews +11 more
20120 citations
Semantic Scholar
Immunomodulatory properties of the histone deacetylase inhibitor vorinostat
A. West
20120 citations
Semantic Scholar
1001 ORAL Anti-cancer Therapy Mediated by a Histone Deacytelase Inhibitor Engages the Immune System
A. West, A. Christiansen, S. Mattarollo, K. Banks +5 more
20110 citations
Semantic Scholar
Methylation of the ITGA2 promoter in Prostate Cancer
A. Short, A. West, Briony Patterson, A. Polanowski +2 more
20090 citations
Semantic Scholar

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