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T. Berthoud · SciRah

Researcher profile · Semantic Scholar

T. Berthoud

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T. Berthoud — researcher profile on SciRah

h-index: 28
Works: 58
Citations: 3,249

Most-cited papers

Potent CD8+ T-Cell Immunogenicity in Humans of a Novel Heterosubtypic Influenza A Vaccine, MVA−NP+M1
T. Berthoud, M. Hamill, P. Lillie, L. Hwenda +8 more
2011Clinical Infectious Diseases397 citations Open access
Semantic Scholar
Enhanced T cell-mediated protection against malaria in human challenges by using the recombinant poxviruses FP9 and modified vaccinia virus Ankara.
D. Webster, S. Dunachie, J. Vuola, T. Berthoud +12 more
2005Proceedings of the National Academy of Sciences of the United States of America260 citations Open access
Semantic Scholar
Preliminary Assessment of the Efficacy of a T-Cell–Based Influenza Vaccine, MVA-NP+M1, in Humans
P. Lillie, T. Berthoud, T. Powell, T. Lambe +15 more
2012Clinical Infectious Diseases258 citations Open access
Semantic Scholar
Prime-Boost Immunization with Adenoviral and Modified Vaccinia Virus Ankara Vectors Enhances the Durability and Polyfunctionality of Protective Malaria CD8+ T-Cell Responses
A. Reyes-Sandoval, T. Berthoud, N. Alder, L. Siani +5 more
2009Infection and Immunity195 citations Open access
Semantic Scholar
Clinical Assessment of a Novel Recombinant Simian Adenovirus ChAdOx1 as a Vectored Vaccine Expressing Conserved Influenza A Antigens
R. Antrobus, L. Coughlan, T. Berthoud, Matthew D. J. Dicks +3 more
2013Molecular Therapy187 citations Open access
Semantic Scholar
Differential Immunogenicity of Various Heterologous Prime-Boost Vaccine Regimens Using DNA and Viral Vectors in Healthy Volunteers1
J. Vuola, S. Keating, D. Webster, T. Berthoud +3 more
2005Journal of Immunology172 citations Open access
Semantic Scholar
A DNA Prime-Modified Vaccinia Virus Ankara Boost Vaccine Encoding Thrombospondin-Related Adhesion Protein but Not Circumsporozoite Protein Partially Protects Healthy Malaria-Naive Adults against Plasmodium falciparum Sporozoite Challenge
S. Dunachie, M. Walther, J. Epstein, S. Keating +17 more
2006Infection and Immunity170 citations Open access
Semantic Scholar
Durable Human Memory T Cells Quantifiable by Cultured Enzyme-Linked Immunospot Assays Are Induced by Heterologous Prime Boost Immunization and Correlate with Protection against Malaria1
S. Keating, P. Bejon, T. Berthoud, J. Vuola +7 more
2005Journal of Immunology138 citations
Semantic Scholar
A T Cell-Inducing Influenza Vaccine for the Elderly: Safety and Immunogenicity of MVA-NP+M1 in Adults Aged over 50 Years
R. Antrobus, P. Lillie, T. Berthoud, Alexandra J. Spencer +7 more
2012PLoS ONE134 citations Open access
Semantic Scholar
Synergistic DNA-MVA prime-boost vaccination regimes for malaria and tuberculosis.
S. Gilbert, V. Moorthy, Laura Andrews, A. Pathan +7 more
2006Vaccine115 citations
Semantic Scholar
Coadministration of seasonal influenza vaccine and MVA-NP+M1 simultaneously achieves potent humoral and cell-mediated responses.
R. Antrobus, T. Berthoud, Caitlin E. Mullarkey, K. Hoschler +4 more
2014Molecular Therapy113 citations Open access
Semantic Scholar
Single‐dose immunogenicity and protective efficacy of simian adenoviral vectors against Plasmodium berghei
A. Reyes-Sandoval, S. Sridhar, T. Berthoud, A. Moore +6 more
2008European Journal of Immunology100 citations
Semantic Scholar
A clinical trial of prime-boost immunisation with the candidate malaria vaccines RTS,S/AS02A and MVA-CS.
S. Dunachie, M. Walther, J. Vuola, D. Webster +19 more
2006Vaccine98 citations
Semantic Scholar
Safety, immunogenicity and efficacy of a pre-erythrocytic malaria candidate vaccine, ICC-1132 formulated in Seppic ISA 720.
M. Walther, S. Dunachie, S. Keating, J. Vuola +18 more
2005Vaccine82 citations
Semantic Scholar
Correction: Evidence of Blood Stage Efficacy with a Virosomal Malaria Vaccine in a Phase IIa Clinical Trial
F. Thompson, David W. Porter, S. Okitsu, Nicole Westerfeld +14 more
2011PLoS ONE81 citations Open access
Semantic Scholar
The relationship between human effector and memory T cells measured by ex vivo and cultured ELISPOT following recent and distal priming
S. Todryk, A. Pathan, S. Keating, David W. Porter +4 more
2009Immunology73 citations Open access
Semantic Scholar
Safety, Immunogenicity, and Efficacy of Prime-Boost Immunization with Recombinant Poxvirus FP9 and Modified Vaccinia Virus Ankara Encoding the Full-Length Plasmodium falciparum Circumsporozoite Protein
M. Walther, F. Thompson, S. Dunachie, S. Keating +15 more
2006Infection and Immunity71 citations
Semantic Scholar
Examination of Influenza Specific T Cell Responses after Influenza Virus Challenge in Individuals Vaccinated with MVA-NP+M1 Vaccine
T. Powell, Yan-Chun Peng, T. Berthoud, Marie-Ève Blais +6 more
2013PLoS ONE60 citations Open access
Semantic Scholar
A human Phase I/IIa malaria challenge trial of a polyprotein malaria vaccine
David W. Porter, F. Thompson, T. Berthoud, Claire L. Hutchings +12 more
2011Vaccine52 citations Open access
Semantic Scholar
Interleukin-10 (IL-10) Polymorphisms Are Associated with IL-10 Production and Clinical Malaria in Young Children
Gui-Cheng Zhang, M. N. Manaca, Michelle McNamara-Smith, A. Mayor +15 more
2012Infection and Immunity46 citations Open access
Semantic Scholar
Comparison of commercial kits to measure cytokine responses to Plasmodium falciparum by multiplex microsphere suspension array technology
T. Berthoud, M. N. Manaca, Diana Quelhas, R. Aguilar +5 more
2011Malaria Journal40 citations Open access
Semantic Scholar
MIG (CXCL9) is a more sensitive measure than IFN-γ of vaccine induced T-cell responses in volunteers receiving investigated malaria vaccines
T. Berthoud, S. Dunachie, S. Todryk, A. Hill +1 more
2009JIM - Journal of Immunological Methods40 citations Open access
Semantic Scholar
An enveloped virus-like particle vaccine expressing a stabilized prefusion form of the SARS-CoV-2 spike protein elicits highly potent immunity
A. Fluckiger, Barthelemy Ontsouka, Jasminka Bozic, Abebaw G. Diress +9 more
2021Vaccine36 citations Open access
Semantic Scholar
Early Gamma Interferon and Interleukin-2 Responses to Vaccination Predict the Late Resting Memory in Malaria-Naïve and Malaria-Exposed Individuals
P. Bejon, S. Keating, J. Mwacharo, O. Kai +12 more
2006Infection and Immunity32 citations Open access
Semantic Scholar
IL-23 signaling in Th17 cells is inhibited by HIV infection and is not restored by HAART: Implications for persistent immune activation
Jason Fernandes, T. Berthoud, Ashok Kumar, J. Angel
2017PLoS ONE31 citations Open access
Semantic Scholar
Prime-Boost Immunization with Adenoviral and Modified Vaccinia Virus Ankara Vectors Enhances the Durability and Polyfunctionality of Protective Malaria CD8+ T-Cell Responses
A. Reyes-Sandoval, T. Berthoud, N. Alder, L. Siani +5 more
2011Infection and Immunity31 citations Open access
Semantic Scholar
Safety and immunogenicity of the malaria candidate vaccines FP9 CS and MVA CS in adult Gambian men.
E. Imoukhuede, T. Berthoud, Paul J. Milligan, K. Bojang +13 more
2006Vaccine30 citations
Semantic Scholar
LOW-LEVEL MALARIA INFECTIONS DETECTED BY A SENSITIVE POLYMERASE CHAIN REACTION ASSAY AND USE OF THIS TECHNIQUE IN THE EVALUATION OF MALARIA VACCINES IN AN ENDEMIC AREA
E. Imoukhuede, Laura Andrews, P. Milligan, T. Berthoud +11 more
2007American Journal of Tropical Medicine and Hygiene29 citations Open access
Semantic Scholar
Boosting BCG vaccination with MVA85A down-regulates the immunoregulatory cytokine TGF-β1
H. Fletcher, A. Pathan, T. Berthoud, S. Dunachie +5 more
2008Vaccine28 citations Open access
Semantic Scholar
Transcriptional changes induced by candidate malaria vaccines and correlation with protection against malaria in a human challenge model
S. Dunachie, T. Berthoud, A. Hill, H. Fletcher
2015Vaccine24 citations Open access
Semantic Scholar
Comparing human T cell and NK cell responses in viral-based malaria vaccine trials.
T. Berthoud, H. Fletcher, David W. Porter, F. Thompson +2 more
2009Vaccine20 citations
Semantic Scholar
MIG and the Regulatory Cytokines IL-10 and TGF-β1 Correlate with Malaria Vaccine Immunogenicity and Efficacy
S. Dunachie, T. Berthoud, S. Keating, A. Hill +1 more
2010PLoS ONE19 citations Open access
Semantic Scholar
High production of pro-inflammatory cytokines by maternal blood mononuclear cells is associated with reduced maternal malaria but increased cord blood infection
C. Dobaño, T. Berthoud, M. N. Manaca, Augusto J. Nhabomba +12 more
2018Malaria Journal17 citations Open access
Semantic Scholar
A balanced pro-inflammatory and regulatory cytokine signature in young African children is associated with lower risk of clinical malaria.
C. Dobaño, Augusto J. Nhabomba, M. N. Manaca, T. Berthoud +12 more
2018Clinical Infectious Diseases13 citations Open access
Semantic Scholar
IL-7-induced proliferation of peripheral Th17 cells is impaired in HAART-controlled HIV infection
Sandra C. Côté, Alana Stilla, Stephanie C. Burke Schinkel, T. Berthoud +1 more
2019AIDS (London)12 citations Open access
Semantic Scholar
Soluble IL-7Rα/sCD127 in Health, Disease, and Its Potential Role as a Therapeutic Agent
P. Barros, T. Berthoud, Nawaf A Aloufi, J. Angel
2021ImmunoTargets and Therapy11 citations Open access
Semantic Scholar
IL‐7 induces sCD127 release and mCD127 downregulation in human CD8+ T cells by distinct yet overlapping mechanisms, both of which are impaired in HIV infection
Sandra C. Côté, Stephanie C. Burke Schinkel, T. Berthoud, P. Barros +4 more
2020European Journal of Immunology10 citations Open access
Semantic Scholar
Evaluation of tumor responses and overall survival in patients with recurrent glioblastoma (GBM) from a phase IIa trial of a CMV vaccine immunotherapeutic candidate (VBI-1901).
P. Wen, D. Reardon, D. Forst, E. Lee +7 more
2022Journal of Clinical Oncology6 citations
Semantic Scholar
Evidence of Blood Stage Efficacy with a Virosomal Malaria Vaccine in a Phase IIa Clinical Trial
F. Thompson, David W. Porter, S. Okitsu, Nicole Westerfeld +14 more
2008PLoS ONE6 citations Open access
Semantic Scholar
Comparative analysis of human gut- and blood-derived mononuclear cells: contrasts in function and phenotype
Stephanie C. Burke Schinkel, P. Barros, T. Berthoud, S. Byrareddy +3 more
2024Frontiers in Immunology5 citations Open access
Semantic Scholar
An enveloped virus-like particle vaccine expressing a stabilized prefusion form of the SARS-CoV-2 spike protein elicits potent immunity after a single dose
A. Fluckiger, Barthelemy Ontsouka, Jasminka Bozic, Abebaw G. Diress +9 more
2021bioRxiv2 citations Open access
Semantic Scholar
Use of eVLP-based vaccine candidates to broaden immunity against SARS-CoV-2 variants
Jasminka Bozic, Tanvir Ahmed, Barthelemy Ontsouka, A. Fluckiger +7 more
2021bioRxiv2 citations Open access
Semantic Scholar
Cord Blood IL-12 Confers Protection to Clinical Malaria in Early Childhood Life
Yong Song, R. Aguilar, Jing Guo, M. N. Manaca +13 more
2018Scientific Reports2 citations Open access
Semantic Scholar
Abstract 6538: CMV-specific immuno-dysregulation in recurrent glioblastoma patients can be overcome with therapeutic vaccination which is associated with tumor response and overall survival benefits in a Phase I/IIA study
T. Berthoud, Felicia Deonarine, S. Chung, C. Soare +2 more
2020Clinical research1 citations
Semantic Scholar
The relationship between human effector and memory T cells measured by ex vivo and cultured ELISPOT following recent and distal priming
S. Todryk, T. Berthoud, F. Thompson, A. Hill +3 more
20111 citations Open access
Semantic Scholar
Corrigendum to “MIG (CXCL9) is a more sensitive measure than IFN-γ of vaccine induced T-cell responses in volunteers receiving investigated malaria vaccines” [J. Immunol. Methods 340 (2009) 33–41]
T. Berthoud, S. Dunachie, S. Todryk, A. Hill +1 more
2011JIM - Journal of Immunological Methods1 citations Open access
Semantic Scholar
T-cell responses to PreS1 and PreS2 are correlated to anti-HBs antibody titres, which are higher and persist longer in volunteers vaccinated with 3-antigen than with 1-antigen hepatitis B vaccine in the PROTECT Study: 3.5 year follow-up
F. Diaz-Mitoma, T. Vesikari, T. Berthoud, D. Plaksin +2 more
2023Journal of Hepatology0 citations
Semantic Scholar
CTIM-14. COMPREHENSIVE BIOMARKER ANALYSIS OF RESPONDERS AND NON-RESPONDERS IN A PHASE IIA TRIAL OF A CMV VACCINE IMMUNOTHERAPEUTIC CANDIDATE (VBI-1901)
P. Wen, D. Reardon, D. Forst, E. Lee +7 more
2022Neuro-Oncology0 citations Open access
Semantic Scholar
Why acute inflammatory response can happen after Adenoviral Vector Vaccines; Is the interleukin 6 the secret and how circumvent that, Is by adding polyethylene glycol (PEG)?
R. Antrobus, L. Coughlan, T. Berthoud, Matthew D. J. Dicks +4 more
20210 citations
Semantic Scholar
High production of pro-inflammatory cytokines by maternal blood mononuclear cells is associated with reduced maternal malaria but increased cord blood infection
C. Dobaño, T. Berthoud, M. N. Manaca, Augusto J. Nhabomba +12 more
2018Malaria Journal0 citations Open access
Semantic Scholar

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