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M. Feany · SciRah

Researcher profile · Semantic Scholar

M. Feany

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M. Feany — researcher profile on SciRah

h-index: 62
Works: 148
Citations: 19K

Most-cited papers

Sirtuin 2 Inhibitors Rescue α-Synuclein-Mediated Toxicity in Models of Parkinson's Disease
T. Outeiro, Eirene Kontopoulos, Stephen M. Altmann, I. Kufareva +11 more
2007Science966 citations Open access
Semantic Scholar
Parkinson's disease: genetics and pathogenesis.
J. Shulman, P. De Jager, M. Feany
2011Annual Review of Pathology800 citations
Semantic Scholar
Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease.
T. Outeiro, Eirene Kontopoulos, Stephen M. Altmann, I. Kufareva +11 more
2007Science536 citations
Semantic Scholar
Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy
G. Kovács, I. Ferrer, L. Grinberg, I. Alafuzoff +68 more
2015Acta Neuropathologica492 citations Open access
Semantic Scholar
Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo
T. Fulga, I. Elson-Schwab, V. Khurana, M. L. Steinhilb +3 more
2007Nature Cell Biology461 citations
Semantic Scholar
Tau promotes neurodegeneration through global chromatin relaxation
B. Frost, M. Hemberg, Jada Lewis, M. Feany
2014Nature Neuroscience458 citations Open access
Semantic Scholar
Tau promotes neurodegeneration via DRP1 mislocalization in vivo
Brian DuBoff, J. Götz, M. Feany
2012Neuron386 citations Open access
Semantic Scholar
Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo
V. Cullen, M. Lindfors, J. Ng, A. Paetau +9 more
2009Molecular Brain285 citations Open access
Semantic Scholar
Tyrosine and serine phosphorylation of alpha-synuclein have opposing effects on neurotoxicity and soluble oligomer formation.
Li Chen, Magali Periquet, Xu Wang, A. Negro +3 more
2009Journal of Clinical Investigation243 citations Open access
Semantic Scholar
Lamin Dysfunction Mediates Neurodegeneration in Tauopathies
B. Frost, Farah H. Bardai, M. Feany
2015Current Biology227 citations Open access
Semantic Scholar
α-synuclein induces mitochondrial dysfunction through spectrin and the actin cytoskeleton
Dalila G. Ordonez, Michael K. Lee, M. Feany
2017Neuron205 citations Open access
Semantic Scholar
Tau phosphorylation sites work in concert to promote neurotoxicity in vivo.
M. L. Steinhilb, Dora Dias-Santagata, T. Fulga, Daniel L. Felch +1 more
2007Molecular Biology of the Cell194 citations Open access
Semantic Scholar
Clinical Correlates in an Experimental Model of Repetitive Mild Brain Injury
R. Mannix, William P. Meehan, J. Mandeville, P. E. Grant +12 more
2013Annals of Neurology172 citations Open access
Semantic Scholar
Why size matters - balancing mitochondrial dynamics in Alzheimer's disease.
Brian DuBoff, M. Feany, J. Götz
2013Trends in Neurosciences168 citations
Semantic Scholar
Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms.
J. Shulman, Selina H. Imboywa, N. Giagtzoglou, M. Powers +9 more
2014Human Molecular Genetics166 citations Open access
Semantic Scholar
Development / Plasticity / Repair
Bale, Deanna L. Benson, C. Bernard, J. Diamond +29 more
2012159 citations
Semantic Scholar
Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS
Ji-Ou Wang, G. Farr, C. Zeiss, D. Rodriguez-Gil +9 more
2009Proceedings of the National Academy of Sciences of the United States of America155 citations Open access
Semantic Scholar
The Parkinson’s disease protein alpha-synuclein is a modulator of Processing-bodies and mRNA stability
Erinc Hallacli, C. Kayatekin, S. Nazeen, Xiou H. Wang +23 more
2022Cell153 citations Open access
Semantic Scholar
Lysosomal Dysfunction Promotes Cleavage and Neurotoxicity of Tau In Vivo
V. Khurana, I. Elson-Schwab, T. Fulga, Katherine A. Sharp +5 more
2010PLoS Genetics150 citations Open access
Semantic Scholar
Brief Communications In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons
T. Spires-Jones, Alix de Calignon, T. Matsui, C. Zehr +10 more
2008138 citations
Semantic Scholar
Alpha-Synuclein S129 Phosphorylation Mutants Do Not Alter Nigrostriatal Toxicity in a Rat Model of Parkinson Disease
Nikolaus R. McFarland, Zhan-Yun Fan, Kui Xu, M. Schwarzschild +3 more
2009Journal of Neuropathology and Experimental Neurology121 citations Open access
Semantic Scholar
Connecting the Dots Between Tau Dysfunction and Neurodegeneration
B. Frost, J. Götz, M. Feany
2014Trends in Cell Biology115 citations Open access
Semantic Scholar
S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila
Michelle L. Steinhilb, Dora Dias-Santagata, Erin E. Mulkearns, J. Shulman +3 more
2007Journal of Neuroscience Research110 citations
Semantic Scholar
Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington’s disease model
Sheng Zhang, M. Feany, S. Saraswati, J. Littleton +1 more
2009Disease Models & Mechanisms96 citations Open access
Semantic Scholar
The Unfolded Protein Response Protects from Tau Neurotoxicity In Vivo
Carin A. Loewen, M. Feany
2010PLoS ONE86 citations Open access
Semantic Scholar
Parkinson's disease: Insights from non-traditional model organisms
I. Pienaar, J. Götz, M. Feany
2010Progress in neurobiology79 citations
Semantic Scholar
Functional screening of Alzheimer pathology genome-wide association signals in Drosophila.
J. Shulman, Portia I. Chipendo, Lori B. Chibnik, C. Aubin +7 more
2011American Journal of Human Genetics78 citations Open access
Semantic Scholar
Protein misfolding and oxidative stress promote glial-mediated neurodegeneration in an Alexander disease model
Liqun Wang, Kenneth J. Colodner, M. Feany
2011Journal of Neuroscience75 citations Open access
Semantic Scholar
Circular RNAs in the human brain are tailored to neuron identity and neuropsychiatric disease
Xian-Jun Dong, Yun-Fei Bai, Zhi-Xiang Liao, David Gritsch +8 more
2023Nature Communications74 citations Open access
Semantic Scholar
A genetic basis for the variable effect of smoking/nicotine on Parkinson's disease
Erin M. Hill-Burns, Navjot Singh, Prabarna Ganguly, T. Hamza +12 more
2012The Pharmacogenomics Journal74 citations Open access
Semantic Scholar
p53 prevents neurodegeneration by regulating synaptic genes
P. Merlo, B. Frost, Shouyong Peng, Y. Yang +2 more
2014Proceedings of the National Academy of Sciences of the United States of America71 citations Open access
Semantic Scholar
Glial fibrillary tangles and JAK/STAT-mediated glial and neuronal cell death in a Drosophila model of glial tauopathy
Kenneth J. Colodner, M. Feany
2010Journal of Neuroscience71 citations Open access
Semantic Scholar
α-synuclein impairs autophagosome maturation through abnormal actin stabilization
S. Sarkar, Abby L. Olsen, Katja Sygnecka, K. M. Lohr +1 more
2021PLoS Genetics70 citations Open access
Semantic Scholar
Alexander Disease
A. Messing, M. Brenner, M. Feany, M. Nedergaard +1 more
2012Journal of Neuroscience64 citations Open access
Semantic Scholar
A neuroprotective role for the DNA damage checkpoint in tauopathy
V. Khurana, P. Merlo, Brian DuBoff, T. Fulga +4 more
2012Aging Cell57 citations
Semantic Scholar
Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander disease
Liqun Wang, Jing Xia, Jonathan Li, Tracy L. Hagemann +6 more
2018Nature Communications56 citations Open access
Semantic Scholar
Nitric oxide mediates glial-induced neurodegeneration in Alexander disease
Liqun Wang, Tracy L. Hagemann, H. Kalwa, T. Michel +2 more
2015Nature Communications54 citations Open access
Semantic Scholar
Antisense therapy in a rat model of Alexander disease reverses GFAP pathology, white matter deficits, and motor impairment
Tracy L. Hagemann, Berit Powers, Ni-Hsuan Lin, A. Mohamed +10 more
2021Science Translational Medicine53 citations Open access
Semantic Scholar
Lrrk promotes tau neurotoxicity through dysregulation of actin and mitochondrial dynamics
Farah H. Bardai, Dalila G. Ordonez, Rachel M. Bailey, Matthew Hamm +2 more
2018PLoS Biology53 citations Open access
Semantic Scholar
Defective Phagocytic Corpse Processing Results in Neurodegeneration and Can Be Rescued by TORC1 Activation
J. Etchegaray, Emma J Elguero, Jennifer A. Tran, V. Sinatra +2 more
2016Journal of Neuroscience53 citations Open access
Semantic Scholar
Biotin rescues mitochondrial dysfunction and neurotoxicity in a tauopathy model
K. M. Lohr, B. Frost, C. Scherzer, M. Feany
2020Proceedings of the National Academy of Sciences of the United States of America41 citations Open access
Semantic Scholar
Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form
T. Collier, K. Srivastava, C. Justman, Tom Grammatopoulous +14 more
2017Neurobiology of Disease40 citations Open access
Semantic Scholar
PARP Inhibitors and Parkinson's Disease
Abby L. Olsen, M. Feany
2019New England Journal of Medicine34 citations
Semantic Scholar
Glial α-synuclein promotes neurodegeneration characterized by a distinct transcriptional program in vivo
Abby L. Olsen, M. Feany
2019Glia34 citations Open access
Semantic Scholar
A Conserved Cytoskeletal Signaling Cascade Mediates Neurotoxicity of FTDP-17 Tau Mutations In Vivo
Farah H. Bardai, Liqun Wang, Yamini Mutreja, Mythili Yenjerla +2 more
2017Journal of Neuroscience33 citations Open access
Semantic Scholar
An In Vivo Pharmacological Screen Identifies Cholinergic Signaling as a Therapeutic Target in Glial-Based Nervous System Disease
Liqun Wang, Tracy L. Hagemann, A. Messing, M. Feany
2016Journal of Neuroscience33 citations Open access
Semantic Scholar
Glia are critical for the neuropathology of complex I deficiency in Drosophila.
Vijay Hegde, Rutger O. Vogel, M. Feany
2014Human Molecular Genetics30 citations Open access
Semantic Scholar
Parkinson’s disease risk genes act in glia to control neuronal α-synuclein toxicity
Abby L. Olsen, M. Feany
2021Neurobiology of Disease26 citations Open access
Semantic Scholar
Mediators of a long-term movement abnormality in a Drosophila melanogaster model of classic galactosemia
E. L. Ryan, Brian DuBoff, M. Feany, J. L. Fridovich-Keil
2012Disease Models & Mechanisms26 citations Open access
Semantic Scholar
Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy
S. Sarkar, Michael A Murphy, E. Dammer, Abby L. Olsen +3 more
2020npj Parkinson's Disease25 citations Open access
Semantic Scholar

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