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A. Kerksiek · SciRah

Researcher profile · Semantic Scholar

A. Kerksiek

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A. Kerksiek — researcher profile on SciRah

h-index: 19
Works: 56
Citations: 2,090

Most-cited papers

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis
K. Wouters, P. J. V. van Gorp, V. Bieghs, M. Gijbels +9 more
2008Hepatology498 citations Open access
Semantic Scholar
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming
S. Zimmer, A. Grebe, S. S. Bakke, Niklas Bode +21 more
2016Science Translational Medicine332 citations Open access
Semantic Scholar
High density lipoprotein mediates anti-inflammatory transcriptional reprogramming of macrophages via the transcriptional repressor ATF3
D. De Nardo, Larisa I. Labzin, H. Kono, R. Seki +23 more
2013Nature Immunology299 citations Open access
Semantic Scholar
Altered levels of plasma 24S- and 27-hydroxycholesterol in demented patients.
H. Kölsch, R. Heun, A. Kerksiek, K. Bergmann +2 more
2004Neuroscience Letters126 citations
Semantic Scholar
Dietary intake of plant sterols stably increases plant sterol levels in the murine brain
T. Vanmierlo, O. Weingärtner, S. V. D. van der Pol, C. Husche +11 more
2012Journal of Lipid Research112 citations Open access
Semantic Scholar
Intrahepatic cholesterol influences progression, inhibition and reversal of non‐alcoholic steatohepatitis in hyperlipidemic mice
K. Wouters, M. van Bilsen, P. J. V. van Gorp, V. Bieghs +5 more
2010FEBS Letters110 citations Open access
Semantic Scholar
Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer’s disease mouse model
Jeroen F. J. Bogie, C. Hoeks, M. Schepers, A. Tiane +20 more
2019Scientific Reports75 citations Open access
Semantic Scholar
Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression
J. Canet-Pons, N. Şen, Aleksandar Arsović, L. Almaguer-Mederos +14 more
2019bioRxiv47 citations Open access
Semantic Scholar
Alterations in Brain Cholesterol Metabolism in the APPSLxPS1mut mouse, a Model for Alzheimer's Disease
T. Vanmierlo, V. Bloks, L. van Vark-van der Zee, K. Rutten +7 more
2010Journal of Alzheimer's Disease47 citations
Semantic Scholar
Dietary plant stanol ester consumption improves immune function in asthma patients: results of a randomized, double-blind clinical trial.
Florence Brüll, E. De Smet, R. Mensink, A. Vreugdenhil +4 more
2016American Journal of Clinical Nutrition39 citations Open access
Semantic Scholar
Carbamazepine increases atherogenic lipoproteins: mechanism of action in male adults.
S. Brämswig, A. Kerksiek, T. Sudhop, C. Luers +2 more
2002American Journal of Physiology. Heart and Circulatory Physiology36 citations
Semantic Scholar
Cholesterol metabolites and plant sterols in cerebrospinal fluid are associated with Alzheimer´s cerebral pathology and clinical disease progression.
Tabea Jahn, C. Clark, A. Kerksiek, P. Lewczuk +2 more
2020Journal of Steroid Biochemistry and Molecular Biology32 citations Open access
Semantic Scholar
SREBP-1a Polymorphism Influences the Risk of Alzheimer’s Disease in Carriers of the ApoE4 Allele
Christian Spell, H. Kölsch, D. Lütjohann, A. Kerksiek +6 more
2004Dementia and Geriatric Cognitive Disorders31 citations
Semantic Scholar
HDL inhibits endoplasmic reticulum stress-induced apoptosis of pancreatic β-cells in vitro by activation of Smoothened[S]
M. Yalçınkaya, A. Kerksiek, Katrin Gebert, W. Annema +5 more
2020Journal of Lipid Research29 citations Open access
Semantic Scholar
First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas- and liquid-chromatography–Urgent need for harmonisation of analytical methods
D. Lütjohann, I. Björkhem, S. Friedrichs, A. Kerksiek +46 more
2019Journal of Steroid Biochemistry and Molecular Biology27 citations Open access
Semantic Scholar
Ursodeoxycholic acid impairs atherogenesis and promotes plaque regression by cholesterol crystal dissolution in mice.
Niklas Bode, A. Grebe, A. Kerksiek, D. Lütjohann +4 more
2016Biochemical and Biophysical Research Communications - BBRC26 citations
Semantic Scholar
24(S)-Saringosterol Prevents Cognitive Decline in a Mouse Model for Alzheimer’s Disease
N. Martens, M. Schepers, Na Zhan, F. Leijten +12 more
2021Marine Drugs25 citations Open access
Semantic Scholar
Plasma levels of the oxyphytosterol 7α-hydroxycampesterol are associated with cardiovascular events.
A. Fuhrmann, O. Weingärtner, S. Meyer, B. Cremers +13 more
2018Atherosclerosis23 citations
Semantic Scholar
Low serum lathosterol levels associate with fatal cardiovascular disease and excess all-cause mortality: a prospective cohort study
O. Weingärtner, D. Lütjohann, S. Meyer, A. Fuhrmann +14 more
2019Clinical Research in Cardiology19 citations
Semantic Scholar
Deleting myeloid IL-10 receptor signalling attenuates atherosclerosis in LDLR-/- mice by altering intestinal cholesterol fluxes
J. Stöger, Marieke C. S. Boshuizen, G. Brufau, M. Gijbels +13 more
2016Thrombosis and Haemostasis19 citations Open access
Semantic Scholar
Acute Intake of Plant Stanol Esters Induces Changes in Lipid and Lipoprotein Metabolism-Related Gene Expression in the Liver and Intestines of Mice
E. De Smet, R. Mensink, M. Konings, G. Brufau +6 more
2015Lipids16 citations Open access
Semantic Scholar
Increased cholesterol absorption is associated with In-stent-restenosis after stent implantation for stable coronary artery disease.
S. Otto, D. Lütjohann, A. Kerksiek, S. Friedrichs +4 more
2022Steroids15 citations Open access
Semantic Scholar
International descriptive and interventional survey for oxycholesterol determination by gas- and liquid-chromatographic methods.
D. Lütjohann, I. Björkhem, S. Friedrichs, A. Kerksiek +27 more
2018Biochimie15 citations Open access
Semantic Scholar
Importance of γ-secretase in the regulation of liver X receptor and cellular lipid metabolism
Esteban Gutiérrez, D. Lütjohann, A. Kerksiek, M. Fabiano +4 more
2020Life Science Alliance14 citations Open access
Semantic Scholar
Plant sterols and cholesterol metabolism are associated with five-year cognitive decline in the elderly population
C. Clark, Mehdi Gholam, Leonardo Zullo, A. Kerksiek +5 more
2023iScience11 citations Open access
Semantic Scholar
24(R, S)-Saringosterol From artefact to a biological medical agent.
K. Vanbrabant, David Van Meel, A. Kerksiek, S. Friedrichs +9 more
2021Journal of Steroid Biochemistry and Molecular Biology11 citations Open access
Semantic Scholar
Identification of Correlative Shifts in Indices of Brain Cholesterol Metabolism in the C57BL6/Mecp2tm1.1Bird Mouse, a Model for Rett Syndrome.
D. Lütjohann, Adam M. Lopez, J. Chuang, A. Kerksiek +1 more
2018Lipids11 citations
Semantic Scholar
Serum 4β-hydroxycholesterol increases during fluconazole treatment
D. Lütjohann, F. Stellaard, A. Kerksiek, J. Lötsch +1 more
2020European Journal of Clinical Pharmacology10 citations Open access
Semantic Scholar
Cholesterol-metabolism, plant sterols, and long-term cognitive decline in older people – Effects of sex and APOEe4
Matteo Spinedi, Christopher Clark, Leonardo Zullo, A. Kerksiek +6 more
2024iScience8 citations Open access
Semantic Scholar
Anti‐PCSK 9 antibodies increase the ratios of the brain‐specific oxysterol 24S‐hydroxycholesterol to cholesterol and to 27‐hydroxycholesterol in the serum
D. Lütjohann, F. Stellaard, Bediha Bölükbasi, A. Kerksiek +2 more
2021British Journal of Clinical Pharmacology8 citations Open access
Semantic Scholar
Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis
Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek +24 more
2023Journal of Biological Chemistry7 citations Open access
Semantic Scholar
Plasma oxyphytosterols most likely originate from hepatic oxidation and subsequent spill-over in the circulation.
S. Baumgartner, D. Lütjohann, C. Husche, A. Kerksiek +3 more
2021Journal of Steroid Biochemistry and Molecular Biology5 citations Open access
Semantic Scholar
Presenilin Deficiency Results in Cellular Cholesterol Accumulation by Impairment of Protein Glycosylation and NPC1 Function
M. Fabiano, Naoto Oikawa, A. Kerksiek, Jun-ichi Furukawa +8 more
2024International Journal of Molecular Sciences4 citations Open access
Semantic Scholar
RER1 regulates lipid metabolism in monocytes and macrophages
Yanxia Liu, S. Theil, Mohamed H. Yaghmour, A. Kerksiek +7 more
2025Cellular and Molecular Life Sciences2 citations Open access
Semantic Scholar
Reducing CETP activity prevents memory decline in an Alzheimer’s disease mouse model
J. Phénix, I. Sarty, Megan S. Katz, Hannah Nie +6 more
2024bioRxiv2 citations Open access
Semantic Scholar
Comparative proximity biotinylation implicates RAB18 in sterol mobilization and biosynthesis
Robert S. Kiss, Jarred Chicoine, Youssef Khalil, R. Sladek +15 more
2019bioRxiv2 citations Open access
Semantic Scholar
The COPI coatomer regulates several steps of HDL metabolism
G. Panteloglou, P. Zanoni, C. S. Law, B. Woods +29 more
2026Arteriosclerosis, Thrombosis and Vascular Biology1 citations Open access
Semantic Scholar
The use of seaweed-derived phytosterols to defeat Alzheimer's Disease
N. Martens, M. Schepers, N. Zhan, F. Leijten +12 more
2022Atherosclerosis1 citations Open access
Semantic Scholar
A central role for cholesterol metabolism and inflammation during the inhibition of non-alcoholic steatohepatitis with a synthetic PPAR alpha agonist
K. Wouters, M. van Bilsen, V. Bieghs, P. J. V. van Gorp +5 more
20081 citations
Semantic Scholar
Impact of Breast Cancer on Ovarian Function: Dysregulation of Cholesterol Homeostasis in Cumulus Cells and Follicular Fluid
A. Poitrinal, L. Dupont, S. Dollet, A. Kerksiek +9 more
2026Cancers0 citations Open access
Semantic Scholar
The COPI coatomer influences LDL receptor activity, hepatic lipid storage, and apoB secretion.
G. Panteloglou, J. Robert, M. Smit, N. Huijkman +26 more
2026Atherosclerosis0 citations Open access
Semantic Scholar
Reducing CETP activity prevents memory decline in an Alzheimer’s disease mouse model
J. Phénix, I. Sarty, Megan S. Katz, Antonio Vázquez Cobá +10 more
2026EMBO Molecular Medicine0 citations Open access
Semantic Scholar
Predicting LDL-cholesterol reduction variability on statin-ezetimibe therapy: insights from "Jena auf Ziel".
U. Makhmudova, D. Lütjohann, F. Haertel, A. Kerksiek +7 more
2026Herz0 citations Open access
Semantic Scholar
The COPI coatomer influences LDL receptor activity, hepatic lipid storage, and apoB secretion
G. Panteloglou, J. Robert, M. Smit, N. Huijkman +26 more
2026bioRxiv0 citations Open access
Semantic Scholar
The COPI coatomer regulates several steps of HDL metabolism
G. Panteloglou, P. Zanoni, C. S. Law, B. Woods +27 more
2025medRxiv0 citations Open access
Semantic Scholar
Plant Sterols, Cholesterol Metabolism, and Cognitive Decline in the Older People: A Population-Based Study
C. Clark, Mehdi Gholam, Leonardo Zullo, A. Kerksiek +5 more
2022Social Science Research Network0 citations
Semantic Scholar
associated In-stent-restenosis after stent implantation for stable coronary artery disease
Sylvia Otto, D. Lütjohann, A. Kerksiek, S. Friedrichs +6 more
20220 citations
Semantic Scholar
P5625Markers for cholesterol absorption are associated with In-stent-restenosis after coronary stenting in stable coronary artery disease: An Optical Coherence Tomography study
S. Otto, D. Luetjohann, A. Kerksiek, S. Friedrichs +3 more
2019European Heart Journal0 citations
Semantic Scholar
P1544No associations of plasma oxyphytosterol levels and cardiovascular events in patients admitted for coronary angiography
A. Fuhrmann, O. Weingaertner, S. Meyer, B. Cremers +11 more
2018European Heart Journal0 citations Open access
Semantic Scholar
P6434Low serum lathosterol levels predict fatal cardiovascular disease and all cause mortality: a prospective cohort study in patients admitted for coronary angiography
O. Weingaertner, D. Luetjohann, S. Meyer, S. Seiler-Mussler +11 more
2018European Heart Journal0 citations
Semantic Scholar

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