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L. Ittner · SciRah

Researcher profile · Semantic Scholar

L. Ittner

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L. Ittner — researcher profile on SciRah

h-index: 63
Works: 220
Citations: 15K

Most-cited papers

The frontotemporal dementia-motor neuron disease continuum.
J. Burrell, G. Halliday, J. Kril, L. Ittner +3 more
2016The Lancet339 citations
Semantic Scholar
Determination and reduction of translocator protein (TSPO) ligand rs6971 discrimination
Renee Sokias, E. Werry, S. W. Chua, Tristan A. Reekie +4 more
2016MedChemComm256 citations Open access
Semantic Scholar
Recent Developments in TSPO PET Imaging as A Biomarker of Neuroinflammation in Neurodegenerative Disorders
E. Werry, Fiona Bright, O. Piguet, L. Ittner +6 more
2019International Journal of Molecular Sciences254 citations Open access
Semantic Scholar
Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer’s mice
A. Ittner, S. W. Chua, Josefine Bertz, Alexander M. Volkerling +17 more
2016Science253 citations
Semantic Scholar
Dendritic Tau in Alzheimer's Disease.
A. Ittner, L. Ittner
2018Neuron236 citations Open access
Semantic Scholar
Neuroinflammation in frontotemporal dementia
Fiona Bright, E. Werry, C. Dobson-Stone, O. Piguet +7 more
2019Nature Reviews Neurology223 citations
Semantic Scholar
The Link between Type 2 Diabetes and Neurodegeneration: Roles for Amyloid-β, Amylin, and Tau Proteins
P. Bharadwaj, N. Wijesekara, Milindu Liyanapathirana, P. Newsholme +3 more
2017Journal of Alzheimer's Disease182 citations
Semantic Scholar
Tau exacerbates excitotoxic brain damage in an animal model of stroke
Mian Bi, Amadeus Gladbach, J. van Eersel, A. Ittner +15 more
2017Nature Communications156 citations Open access
Semantic Scholar
Retiring the term FTDP-17 as MAPT mutations are genetic forms of sporadic frontotemporal tauopathies
Shelley L. Forrest, J. Kril, C. Stevens, John B. J. Kwok +11 more
2017Brain : a journal of neurology134 citations Open access
Semantic Scholar
A Comparative Study of Variables Influencing Ischemic Injury in the Longa and Koizumi Methods of Intraluminal Filament Middle Cerebral Artery Occlusion in Mice
Gary P. Morris, Amanda L. Wright, R. Tan, Amadeus Gladbach +2 more
2016PLoS ONE118 citations Open access
Semantic Scholar
ALS/FTLD: experimental models and reality
R. Tan, Ya-Zi D. Ke, L. Ittner, G. Halliday
2017Acta Neuropathologica103 citations
Semantic Scholar
Tau physiology and pathomechanisms in frontotemporal lobar degeneration
L. Bodea, A. Eckert, L. Ittner, O. Piguet +1 more
2016Journal of Neurochemistry86 citations Open access
Semantic Scholar
Physiological changes in neurodegeneration — mechanistic insights and clinical utility
R. Ahmed, Ya-Zi D. Ke, S. Vucic, L. Ittner +5 more
2018Nature Reviews Neurology83 citations
Semantic Scholar
TAU DOWN-REGULATES BDNF EXPRESSION IN ANIMAL AND CELLULAR MODELS OF ALZHEIMER’S DISEASE
Elyse Rosa, S. Mahendram, Ya-Zi D. Ke, L. Ittner +2 more
2016Neurobiology of Aging82 citations Open access
Semantic Scholar
TDP‐43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA‐binding protein hnRNP K and affect the Nrf2 antioxidant pathway
Diane Moujalled, A. Grubman, Karla Acevedo, Shu Yang +13 more
2017Human Molecular Genetics78 citations Open access
Semantic Scholar
TDP-43 and Inflammation: Implications for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Fiona Bright, Gabriella Chan, Annika van Hummel, L. Ittner +1 more
2021International Journal of Molecular Sciences65 citations Open access
Semantic Scholar
SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity
Ramón Martínez-Mármol, Rosina Giordano-Santini, Eva Kaulich, Ann-Na Cho +11 more
2023Science Advances64 citations Open access
Semantic Scholar
Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia
Irina Pleines, Joanne Woods, S. Chappaz, Verity G. Kew +26 more
2017Journal of Clinical Investigation63 citations Open access
Semantic Scholar
Altered serum protein levels in frontotemporal dementia and amyotrophic lateral sclerosis indicate calcium and immunity dysregulation
J. S. Katzeff, Fiona Bright, K. Lo, J. Kril +10 more
2020Scientific Reports53 citations Open access
Semantic Scholar
Assessment of amyloid β in pathologically confirmed frontotemporal dementia syndromes
R. Tan, J. Kril, Yue Yang, Nicole Tom +7 more
2017Alzheimer's & Dementia53 citations Open access
Semantic Scholar
Uncoupling N-acetylaspartate from brain pathology: implications for Canavan disease gene therapy
G. von Jonquieres, Ziggy H. T. Spencer, Benjamin D. Rowlands, Claudia B. Klugmann +15 more
2017Acta Neuropathologica53 citations Open access
Semantic Scholar
An N-terminal motif unique to primate tau enables differential protein–protein interactions
Kristie Stefanoska, Alexander M. Volkerling, Josefine Bertz, A. Poljak +3 more
2018Journal of Biological Chemistry51 citations Open access
Semantic Scholar
PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells
V. Chandrakanthan, Avani Yeola, Jair Kwan, R. Oliver +28 more
2016Proceedings of the National Academy of Sciences of the United States of America48 citations Open access
Semantic Scholar
Generation of a New Tau Knockout (tauΔex1) Line Using CRISPR/Cas9 Genome Editing in Mice
Daniel C. S. Tan, Sherilyn Yao, A. Ittner, Josefine Bertz +3 more
2018Journal of Alzheimer's Disease43 citations Open access
Semantic Scholar
Biomarker discovery and development for frontotemporal dementia and amyotrophic lateral sclerosis
J. S. Katzeff, Fiona Bright, Katherine Phan, J. Kril +7 more
2022Brain : a journal of neurology41 citations Open access
Semantic Scholar
No Overt Deficits in Aged Tau-Deficient C57Bl/6.Mapttm1(EGFP)Kit GFP Knockin Mice
Annika van Hummel, Mian Bi, S. Ippati, Julia van der Hoven +7 more
2016PLoS ONE40 citations Open access
Semantic Scholar
Disinhibition-like behavior in a P301S mutant tau transgenic mouse model of frontotemporal dementia.
Magdalena Przybyla, C. Stevens, Julia van der Hoven, Anne E. Harasta +11 more
2016Neuroscience Letters39 citations
Semantic Scholar
Loss of LAMP5 interneurons drives neuronal network dysfunction in Alzheimer’s disease
Yuanyuan Deng, Mian Bi, Fabien Delerue, Shelley L. Forrest +11 more
2022Acta Neuropathologica35 citations Open access
Semantic Scholar
Rapid initiation of cell cycle reentry processes protects neurons from amyloid-β toxicity
S. Ippati, Yuan-Yuan Deng, Julia van der Hoven, C. Heu +9 more
2021Proceedings of the National Academy of Sciences of the United States of America35 citations Open access
Semantic Scholar
Multiple Mechanisms Linking Type 2 Diabetes and Alzheimer’s Disease: Testosterone as a Modifier
Prita R. Asih, Michelle Tegg, H. Sohrabi, M. Carruthers +5 more
2017Journal of Alzheimer's Disease35 citations Open access
Semantic Scholar
Accelerated aging exacerbates a pre‐existing pathology in a tau transgenic mouse model
L. Bodea, H. Evans, A. Van der Jeugd, L. Ittner +6 more
2017Aging Cell35 citations Open access
Semantic Scholar
The Polyphenol Altenusin Inhibits in Vitro Fibrillization of Tau and Reduces Induced Tau Pathology in Primary Neurons.
S. W. Chua, A. Cornejo, J. van Eersel, C. Stevens +8 more
2017ACS Chemical Neuroscience35 citations Open access
Semantic Scholar
Cell-specific MAPT gene expression is preserved in neuronal and glial tau cytopathologies in progressive supranuclear palsy
Shelley L. Forrest, Seojin Lee, Nasna Nassir, I. Martínez-Valbuena +8 more
2023Acta Neuropathologica33 citations Open access
Semantic Scholar
Neuronal MAP kinase p38α inhibits c-Jun N-terminal kinase to modulate anxiety-related behaviour
Kristie Stefanoska, Josefine Bertz, Alexander M. Volkerling, Julia van der Hoven +2 more
2018Scientific Reports33 citations Open access
Semantic Scholar
Peptides for trans‐blood–brain barrier delivery
Reuben Blades, L. Ittner, O. Tietz
2023Journal of labelled compounds & radiopharmaceuticals32 citations Open access
Semantic Scholar
Cannabidiol (CBD) treatment improves spatial memory in 14-month-old female TAU58/2 transgenic mice.
F. Kreilaus, Magdalena Przybyla, L. Ittner, T. Karl
2022Behavioural Brain Research32 citations
Semantic Scholar
Reduction of advanced tau-mediated memory deficits by the MAP kinase p38γ
A. Ittner, Prita R. Asih, Amanda R P Tan, Emmanuel Prikas +7 more
2020Acta Neuropathologica30 citations
Semantic Scholar
Mouse models of frontotemporal dementia: A comparison of phenotypes with clinical symptomatology.
R. Ahmed, M. Irish, J. van Eersel, A. Ittner +13 more
2017Neuroscience and Biobehavioral Reviews30 citations
Semantic Scholar
Distribution Patterns of Astrocyte Populations in the Human Cortex
Shelley L. Forrest, Jordan Hanxi Kim, D. Crockford, Katharine Huynh +6 more
2022Neurochemical Research29 citations Open access
Semantic Scholar
Pathological manifestation of human endogenous retrovirus K in frontotemporal dementia
Katherine Phan, Ying He, Yu-Hong Fu, N. Dzamko +10 more
2021Communications Medicine29 citations Open access
Semantic Scholar
Adeno‐associated virus‐based Alzheimer's disease mouse models and potential new therapeutic avenues
L. Ittner, M. Klugmann, Ya-Zi D. Ke
2019British Journal of Pharmacology27 citations Open access
Semantic Scholar
In vivocharacterization of the aspartyl-tRNA synthetase DARS: Homing in on the leukodystrophy HBSL.
Dominik Fröhlich, Alexandra K Suchowerska, Ziggy H. T. Spencer, G. von Jonquieres +8 more
2017Neurobiology of Disease26 citations Open access
Semantic Scholar
Sphingosine Kinase 2 Potentiates Amyloid Deposition but Protects against Hippocampal Volume Loss and Demyelination in a Mouse Model of Alzheimer's Disease
Mona Lei, Jonathan D. Teo, Huitong Song, Holly P. McEwen +15 more
2019Journal of Neuroscience25 citations Open access
Semantic Scholar
Methylation of a CGATA element inhibits binding and regulation by GATA-1
Lu Yang, Zhiliang Chen, Elizabeth S. Stout, Fabien Delerue +4 more
2020Nature Communications24 citations Open access
Semantic Scholar
Chronic cannabidiol (CBD) treatment did not exhibit beneficial effects in 4-month-old male TAU58/2 transgenic mice.
Georgia Watt, R. Chesworth, Magdalena Przybyla, A. Ittner +3 more
2020Pharmacology, Biochemistry and Behavior23 citations
Semantic Scholar
Targeting 14-3-3θ-mediated TDP-43 pathology in amyotrophic lateral sclerosis and frontotemporal dementia mice.
Ya-Zi D. Ke, Annika van Hummel, Carol G. Au, Gabriella Chan +17 more
2024Neuron21 citations Open access
Semantic Scholar
ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.
S. Rayner, F. Cheng, A. Hogan, N. Grima +12 more
2021Human Molecular Genetics20 citations
Semantic Scholar
Novel behavioural characteristics of male human P301S mutant tau transgenic mice - a model for tauopathy.
Georgia Watt, Magdalena Przybyla, Valeria Zak, J. van Eersel +3 more
2020Neuroscience19 citations
Semantic Scholar
Nigrostriatal pathology with reduced astrocytes in LRRK2 S910/S935 phosphorylation deficient knockin mice
Ye Zhao, Shikara Keshiya, F. Atashrazm, Jianqun Gao +5 more
2018Neurobiology of Disease18 citations Open access
Semantic Scholar
Generation of Genetically Modified Mice through the Microinjection of Oocytes.
Fabien Delerue, L. Ittner
2017Journal of Visualized Experiments18 citations Open access
Semantic Scholar

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