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B. Tyrberg · SciRah

Researcher profile · Semantic Scholar

B. Tyrberg

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B. Tyrberg — researcher profile on SciRah

h-index: 19
Works: 50
Citations: 1,844

Most-cited papers

Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas
E. Hao, B. Tyrberg, P. Itkin-Ansari, J. Lakey +5 more
2006Nature Medicine230 citations
Semantic Scholar
Sweet taste receptor signaling in beta cells mediates fructose-induced potentiation of glucose-stimulated insulin secretion
George A. Kyriazis, M. M. Soundarapandian, B. Tyrberg
2012Proceedings of the National Academy of Sciences of the United States of America226 citations Open access
Semantic Scholar
β-Cell Differentiation from a Human Pancreatic Cell Line in Vitro and in Vivo
Dominique Dufayet de la Tour, T. Halvorsen, C. Demeterco, B. Tyrberg +6 more
2001127 citations Open access
Semantic Scholar
Artificial Sweeteners Stimulate Adipogenesis and Suppress Lipolysis Independently of Sweet Taste Receptors*
B. Simon, S. Parlee, Brian S. Learman, H. Mori +8 more
2013Journal of Biological Chemistry123 citations Open access
Semantic Scholar
Sensitivity of human pancreatic islets to peroxynitrite‐induced cell dysfunction and death
Carol A. Delaney, B. Tyrberg, L. Bouwens, H. Vaghef +2 more
1996FEBS Letters106 citations Open access
Semantic Scholar
A method for the generation of human stem cell-derived alpha cells
Quinn P. Peterson, A. Veres, Li-Hua Chen, Michael Q. Slama +11 more
2020Nature Communications77 citations Open access
Semantic Scholar
The homocysteine-inducible endoplasmic reticulum (ER) stress protein Herp counteracts mutant α-synuclein-induced ER stress via the homeostatic regulation of ER-resident calcium release channel proteins.
Cherine Belal, N. Ameli, Adam El Kommos, Spencer Bezalel +6 more
2012Human Molecular Genetics73 citations Open access
Semantic Scholar
NeuroD1 in the endocrine pancreas: Localization and dual function as an activator and repressor
P. Itkin-Ansari, Edoardo M. Marcora, I. Geron, B. Tyrberg +7 more
2005Developmental Dynamics73 citations Open access
Semantic Scholar
Sweet Taste Receptor Deficient Mice Have Decreased Adiposity and Increased Bone Mass
B. Simon, Brian S. Learman, S. Parlee, E. Scheller +7 more
2014PLoS ONE72 citations Open access
Semantic Scholar
Stimulated endocrine cell proliferation and differentiation in transplanted human pancreatic islets: effects of the ob gene and compensatory growth of the implantation organ.
B. Tyrberg, J. Ustinov, T. Otonkoski, Arne Andersson
2001Diabetes70 citations Open access
Semantic Scholar
No direct effect of sodium-glucose transporter-2 (SGLT2) activity on glucagon secretion
R. Kuhre, S. M. Ghiasi, Alice E. Adriaenssens, N. J. Wewer Albrechtsen +10 more
2019Diabetologia65 citations Open access
Semantic Scholar
Sweet taste receptors regulate basal insulin secretion and contribute to compensatory insulin hypersecretion during the development of diabetes in male mice.
George A. Kyriazis, Kathleen R. Smith, B. Tyrberg, Tania Hussain +1 more
2014Endocrinology63 citations Open access
Semantic Scholar
Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling
S. M. Ghiasi, Tina Dahlby, Caroline Hede Andersen, L. Haataja +16 more
2019Diabetes59 citations Open access
Semantic Scholar
Beta-cell differentiation from a human pancreatic cell line in vitro and in vivo.
D. de la Tour, T. Halvorsen, C. Demeterco, B. Tyrberg +6 more
2001Molecular Endocrinology59 citations
Semantic Scholar
c-Myc controls proliferation versus differentiation in human pancreatic endocrine cells.
C. Demeterco, P. Itkin-Ansari, B. Tyrberg, L. Ford +2 more
2002Journal of Clinical Endocrinology and Metabolism41 citations Open access
Semantic Scholar
Islet expression of the DNA repair enzyme 8-oxoguanosine DNA glycosylase (Ogg1) in human type 2 diabetes
B. Tyrberg, K. Anachkov, S. Dib, J. Wang-Rodriguez +2 more
2002BMC Endocrine Disorders36 citations Open access
Semantic Scholar
T-cadherin (Cdh13) in association with pancreatic β-cell granules contributes to second phase insulin secretion
B. Tyrberg, P. Miles, Krist T. Azizian, M. Denzel +4 more
2011Islets31 citations Open access
Semantic Scholar
Basic helix–loop–helix gene Hes6 delineates the sensory hair cell lineage in the inner ear
Dong Qian, Kristen Radde‐Gallwitz, Michael C. Kelly, B. Tyrberg +3 more
2006Developmental Dynamics27 citations Open access
Semantic Scholar
Regulation of the β-cell inflammasome and contribution to stress-induced cellular dysfunction and apoptosis.
S. M. Ghiasi, M. S. Dahllöf, Yama Osmai, Mirwais Osmai +11 more
2018Molecular and Cellular Endocrinology26 citations
Semantic Scholar
The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, low concentrations of interleukin 1 β
M. Khilji, D. Verstappen, Tina Dahlby, Michala Cecilie Burstein Prause +10 more
2020PLoS ONE19 citations Open access
Semantic Scholar
The No-Go and Nonsense-Mediated RNA Decay Pathways Are Regulated by Inflammatory Cytokines in Insulin-Producing Cells and Human Islets and Determine β-Cell Insulin Biosynthesis and Survival
S. M. Ghiasi, Nicolai Krogh, B. Tyrberg, T. Mandrup-Poulsen
2018Diabetes19 citations
Semantic Scholar
Growth hormone increases beta-cell proliferation in transplanted human and fetal rat islets.
Erika Höglund, G. Mattsson, B. Tyrberg, A. Andersson +1 more
2009Journal of the Pancreas19 citations
Semantic Scholar
Long noncoding RNAs are dynamically regulated during β-cell mass expansion in mouse pregnancy and control β-cell proliferation in vitro
G. Sisino, Alex-Xianghua Zhou, Niklas Dahr, A. Sabirsh +6 more
2017PLoS ONE17 citations Open access
Semantic Scholar
Cell‐Based Therapies for Diabetes: Progress towards a Transplantable Human β Cell Line
P. Itkin-Ansari, I. Geron, E. Hao, C. Demeterco +2 more
200317 citations
Semantic Scholar
Engraftment and Growth of Transplanted Pancreatic Islets
P. Carlsson, A. Andersson, C. Carlsson, C. Hellerström +10 more
2000Upsala Journal of Medical Sciences17 citations Open access
Semantic Scholar
Saccharin Stimulates Insulin Secretion Dependent on Sweet Taste Receptor-Induced Activation of PLC Signaling Axis
J. Serrano, Nishita N. Meshram, M. M. Soundarapandian, Kathleen R. Smith +4 more
2022Biomedicines16 citations Open access
Semantic Scholar
Inhibition of the prostaglandin D2–GPR44/DP2 axis improves human islet survival and function
Shadab Abadpour, B. Tyrberg, S. W. Schive, Charlotte Wennberg Huldt +8 more
2020Diabetologia16 citations Open access
Semantic Scholar
Promoting islet cell function after transplantation
A. Andersson, P. Carlsson, C. Carlsson, R. Olsson +9 more
2007Cell Biochemistry and Biophysics14 citations
Semantic Scholar
HES6 reverses nuclear reprogramming of insulin-producing cells following cell fusion.
A. Ball, Annelie Abrahamsson, B. Tyrberg, P. Itkin-Ansari +1 more
2007Biochemical and Biophysical Research Communications - BBRC12 citations Open access
Semantic Scholar
Cell-based therapies for diabetes: progress towards a transplantable human beta cell line.
P. Itkin-Ansari, I. Geron, E. Hao, C. Demeterco +2 more
2003Annals of the New York Academy of Sciences12 citations
Semantic Scholar
The long noncoding RNA TUNAR modulates Wnt signaling and regulates human β-cell proliferation.
Alex-Xianghua Zhou, T. Mondal, Ali M. Tabish, Shadab Abadpour +7 more
2021American Journal of Physiology. Endocrinology and Metabolism11 citations
Semantic Scholar
Inhibition of SGLT2 Preserves Function and Promotes Proliferation of Human Islets Cells In Vivo in Diabetic Mice
D. Karlsson, A. Ahnmark, A. Sabirsh, A. Andréasson +6 more
2022Biomedicines10 citations Open access
Semantic Scholar
The inducible β5i proteasome subunit contributes to proinsulin degradation in GRP94 deficient β cells and is overexpressed in type 2 diabetes pancreatic islets.
M. Khilji, S. E. Bresson, D. Verstappen, C. Pihl +14 more
2020American Journal of Physiology. Endocrinology and Metabolism10 citations Open access
Semantic Scholar
Exploring the insulin secretory properties of the PGD2-GPR44/DP2 axis in vitro and in a randomized phase-1 trial of type 2 diabetes patients
S. Skrtic, B. Tyrberg, Malin Broberg, H. Ericsson +13 more
2018PLoS ONE10 citations Open access
Semantic Scholar
No direct effect of SGLT2 activity on glucagon secretion
R. Kuhre, S. M. Ghiasi, Alice E. Adriaenssens, N. Wewer +12 more
20208 citations
Semantic Scholar
MCPIP1 is a novel link between diabetogenic conditions and impaired insulin secretory capacity.
Karolina Tyka, A. Jörns, Alessia Dunst, Yadi Tang +8 more
2021Biochimica et Biophysica Acta - Molecular Basis of Disease7 citations Open access
Semantic Scholar
IAPP Marks Mono-hormonal Stem-cell Derived β Cells that Maintain Stable Insulin Production in vitro and in vivo
Jeffrey C. Davis, Maria Ryaboshapkina, J. H. Kenty, P. Eser +3 more
2024bioRxiv6 citations Open access
Semantic Scholar
Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats
Kaare V. Grunddal, S. Trammell, Cecilie Bæch-Laursen, Daniel B. Andersen +11 more
2022Diabetologia6 citations Open access
Semantic Scholar
Current and future treatment strategies for type 2 diabetes: the beta-cell as a therapeutic target.
B. Tyrberg, F. Levine
2001Current opinion in investigational drugs5 citations
Semantic Scholar
Microcirculation of human pancreatic islets transplanted under the renal capsule of nude mice.
Leif Jansson, B. Tyrberg, Per-Ola Carlsson, A. Nordin +2 more
2001Transplantation4 citations Open access
Semantic Scholar
Genetic Control of β -Cell Mass Homeostasis
M. M. Soundarapandian, Maria L. Nieves, R. Pasquier, U. Bergström +2 more
20101 citations Open access
Semantic Scholar
Neogenesis and alloxan toxicity in pancreatic islets, with special reference to the transplanted human β-cell
B. Tyrberg
19991 citations
Semantic Scholar
SENSITIVITY OF HUMAN AND RAT PANCREATIC ISLETS TO PEROXYNITRITE-MEDIATED CELL DYSFUNCTION AND DEATH
C. Delaney, B. Tyrberg, D. Eizirik
19961 citations
Semantic Scholar
The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, non-toxic concentrations of interleukin 1 β
M. Khilji, D. Verstappen, Tina Dahlby, Michala Cecilie Burstein Prause +10 more
2019bioRxiv0 citations Open access
Semantic Scholar
Independently of Sweet Taste Receptors Adipogenesis and Suppress Lipolysis Artificial Sweeteners Stimulate Metabolism
B. Simon, S. Parlee, Brian S. Learman, H. Mori +8 more
20130 citations
Semantic Scholar
“Tasting” fructose with pancreatic beta-cells: modulation of insulin release by sweet taste receptor signaling and its role in metabolic diseases
George A. Kyriazis, Kathleen R Mosure, M. M. Soundarapandian, Richard E. Pratley +1 more
2012BMC Proceedings0 citations Open access
Semantic Scholar
Differences between humans and rodents in the susceptibility to pancreatic cell injury. Implications for the pathogenesis of diabetes
C. Hellerström, D. Eizirik, A. Andersson, D. Pipeleers +6 more
20090 citations
Semantic Scholar
The DNA Repair Enzyme 8-OxoG DNA Glycosylase (Ogg1) and Its Involvement in the Pathogenesis of Human Type II Diabetes
B. Tyrberg, F. Levine
20020 citations
Semantic Scholar
Human islets in mixed protect mouse pancreatic ß-cells alloxan toxicity
B. Tyrberg, D. Eizirik, S. Marklund, B. Olejnicka +2 more
19990 citations
Semantic Scholar
HUMAN PANCREATIC B-CELL PROLIFERATION IN VITRO AND IN VIVO
B. Tyrberg, D. Eizirik, C. Hellerström, D. Pipeleers +1 more
19960 citations
Semantic Scholar

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P. Itkin-Ansari×8
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S. M. Ghiasi×6

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George A. Kyriazis×5

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