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N. S. Umapathy · SciRah

Researcher profile · Semantic Scholar

N. S. Umapathy

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N. S. Umapathy — researcher profile on SciRah

h-index: 25
Works: 42
Citations: 1,470

Most-cited papers

Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy.
Senthil K. Karunakaran, N. S. Umapathy, M. Thangaraju, T. Hatanaka +4 more
2008Biochemical Journal116 citations
Semantic Scholar
Cloning and functional characterization of human SMCT2 (SLC5A12) and expression pattern of the transporter in kidney.
Elangovan Gopal, N. S. Umapathy, Pamela M. Martin, S. Ananth +5 more
2007Biochimica et Biophysica Acta101 citations Open access
Semantic Scholar
G9a-Mediated Histone Methylation Regulates Ethanol-Induced Neurodegeneration in the Neonatal Mouse Brain
Shivakumar Subbanna, Madhu Shivakumar, N. S. Umapathy, M. Saito +6 more
2013Neurobiology of Disease94 citations Open access
Semantic Scholar
The Short-Chain Fatty Acid Butyrate Attenuates Pulmonary Vascular Remodeling and Inflammation in Hypoxia-Induced Pulmonary Hypertension
V. Karoor, D. Strassheim, T. Sullivan, A. Verin +5 more
2021International Journal of Molecular Sciences82 citations Open access
Semantic Scholar
Ethanol Induced Acetylation of Histone at G9a Exon1 and G9a-Mediated Histone H3 Dimethylation leads to Neurodegeneration in Neonatal Mice
Shivakumar Subbanna, Nagaraja N. Nagre, Madhu Shivakumar, N. S. Umapathy +2 more
2013Neuroscience76 citations Open access
Semantic Scholar
Transport of butyryl-L-carnitine, a potential prodrug, via the carnitine transporter OCTN2 and the amino acid transporter ATB(0,+).
Sonne R. Srinivas, P. Prasad, N. S. Umapathy, V. Ganapathy +1 more
2007American Journal of Physiology - Gastrointestinal and Liver Physiology75 citations Open access
Semantic Scholar
Ethanol Exposure Induces Neonatal Neurodegeneration by Enhancing CB1R Exon1 Histone H4K8 Acetylation and Up-regulating CB1R Function causing Neurobehavioral Abnormalities in Adult Mice
Shivakumar Subbanna, Nagaraja N. Nagre, N. S. Umapathy, B. Pace +1 more
2014International Journal of Neuropsychopharmacology70 citations Open access
Semantic Scholar
Protein kinase C-α and arginase I mediate pneumolysin-induced pulmonary endothelial hyperpermeability.
R. Lucas, Guang Yang, B. Gorshkov, E. Zemskov +18 more
2012American Journal of Respiratory Cell and Molecular Biology65 citations Open access
Semantic Scholar
Agonist of growth hormone-releasing hormone reduces pneumolysin-induced pulmonary permeability edema
R. Lucas, S. Sridhar, F. Rick, B. Gorshkov +10 more
2012Proceedings of the National Academy of Sciences of the United States of America64 citations Open access
Semantic Scholar
Cloning and functional characterization of the proton-coupled electrogenic folate transporter and analysis of its expression in retinal cell types.
N. S. Umapathy, Jaya P. Gnana-Prakasam, P. Martin, B. Mysona +4 more
2007Investigative Ophthalmology and Visual Science61 citations Open access
Semantic Scholar
Transport of Amino Acid Esters and the Amino-Acid-Based Prodrug Valganciclovir by the Amino Acid Transporter ATB0,+
N. S. Umapathy, V. Ganapathy, M. E. Ganapathy
2004Pharmaceutical Research61 citations
Semantic Scholar
The Carboxyl-terminal Domain of Atypical Protein Kinase Cζ Binds to Ceramide and Regulates Junction Formation in Epithelial Cells*
Guang-Hu Wang, K. Krishnamurthy, N. S. Umapathy, A. Verin +1 more
2009Journal of Biological Chemistry60 citations Open access
Semantic Scholar
Expression and function of glutamine transporters SN1 (SNAT3) and SN2 (SNAT5) in retinal Müller cells.
N. S. Umapathy, Wei-Guo Li, B. Mysona, Sylvia L. Smith +1 more
2005Investigative Ophthalmology and Visual Science53 citations Open access
Semantic Scholar
Molecular Mechanisms Involved in Adenosine-Induced Endothelial Cell Barrier Enhancement
N. S. Umapathy, Zhenghong Fan, E. Zemskov, I. Alieva +2 more
2010Vascular pharmacology49 citations Open access
Semantic Scholar
Electrophysiological Characterization and Modeling of the Structure Activity Relationship of the Human Concentrative Nucleoside Transporter 3 (hCNT3)
Huankai Hu, Christopher J. Endres, Cheng Chang, N. S. Umapathy +6 more
2006Molecular Pharmacology48 citations
Semantic Scholar
Extracellular β-nicotinamide adenine dinucleotide (β-NAD) promotes the endothelial cell barrier integrity via PKA- and EPAC1/Rac1-dependent actin cytoskeleton rearrangement
N. S. Umapathy, E. Zemskov, J. Gonzales, B. Gorshkov +4 more
2010Journal of Cellular Physiology46 citations Open access
Semantic Scholar
P2Y Purinergic Receptors, Endothelial Dysfunction, and Cardiovascular Diseases
D. Strassheim, A. Verin, Róbert K. Bátori, H. Nijmeh +8 more
2020International Journal of Molecular Sciences43 citations Open access
Semantic Scholar
Sodium-coupled electrogenic transport of pyroglutamate (5-oxoproline) via SLC5A8, a monocarboxylate transporter.
S. Miyauchi, Elangovan Gopal, E. Babu, Sonne R. Srinivas +5 more
2010Biochimica et Biophysica Acta38 citations Open access
Semantic Scholar
Novel Scintillation Proximity Assay for Measuring Membrane-Associated Steps of Peptidoglycan Biosynthesis inEscherichia coli
B. Chandrakala, Bertha C. Elias, U. Mehra, N. S. Umapathy +3 more
2001Antimicrobial Agents and Chemotherapy34 citations Open access
Semantic Scholar
P2Y receptors as regulators of lung endothelial barrier integrity
E. Zemskov, R. Lucas, A. Verin, N. S. Umapathy
2011Journal of Cardiovascular Disease Research31 citations Open access
Semantic Scholar
The lectin-like domain of TNF protects from listeriolysin-induced hyperpermeability in human pulmonary microvascular endothelial cells — A crucial role for protein kinase C-α inhibition
Chenling Xiong, Guang Yang, Sanjiv Kumar, S. Aggarwal +13 more
2010Vascular pharmacology31 citations Open access
Semantic Scholar
Expression and Function of System N Glutamine Transporters (SN1/SN2 or SNAT3/SNAT5) in Retinal Ganglion Cells
N. S. Umapathy, Dun Ying, P. Martin, Jennifer Duplantier +4 more
2008Investigative Ophthalmology and Visual Science31 citations Open access
Semantic Scholar
CB1R-Mediated Activation of Caspase-3 Causes Epigenetic and Neurobehavioral Abnormalities in Postnatal Ethanol-Exposed Mice
Shivakumar Subbanna, Nagaraja N. Nagre, Madhu Shivakumar, Vikram Joshi +4 more
2018Frontiers in Molecular Neuroscience29 citations Open access
Semantic Scholar
Molecular Characterization of Myosin Phosphatase in Endothelium
Kyung-mi Kim, C. Csortos, Istvan Czikora, D. Fulton +3 more
2012Journal of Cellular Physiology28 citations Open access
Semantic Scholar
Hydrogen Peroxide Decreases Endothelial Nitric Oxide Synthase Promoter Activity through the Inhibition of Sp1 Activity
Sanjiv Kumar, Xu-Tong Sun, D. Wiseman, Jing-Yi Tian +3 more
2009DNA and Cell Biology28 citations Open access
Semantic Scholar
Protective effect of Growth Hormone-Releasing Hormone agonist in bacterial toxin-induced pulmonary barrier dysfunction
Istvan Czikora, S. Sridhar, B. Gorshkov, I. Alieva +12 more
2014Frontiers in Physiology23 citations Open access
Semantic Scholar
β-Nicotinamide adenine dinucleotide attenuates lipopolysaccharide-induced inflammatory effects in a murine model of acute lung injury
N. S. Umapathy, J. Gonzales, Sadanand Fulzele, Kyung-mi Kim +2 more
2012Experimental Lung Research19 citations Open access
Semantic Scholar
Impaired pulmonary endothelial barrier function in sickle cell mice
N. S. Umapathy, J. Gonzales, L. Makala, Hongyang Xu +2 more
2017Haematologica10 citations Open access
Semantic Scholar
Protective Effect of Low 2-O, 3-O Desulfated Heparin (ODSH) Against LPS-Induced Acute Lung Injury in Mice
J. Gonzales, Rahul S. Patil, Thomas P. Kennedy, N. S. Umapathy +2 more
2025Biomolecules2 citations Open access
Semantic Scholar
Hemolysis Induced Activation of Monocytes Is Followed By Inactivation Via Heme-Induced HO-1 Expression
Itia Lee, N. S. Umapathy, Aluya R Oseghale, J. Brittain
20141 citations
Semantic Scholar
Adenosine A 1 Receptors Promote Vasa Vasorum Endothelial Cell Barrier
N. S. Umapathy, E. Kaczmarek, Nooreen Fatteh, N. Burns +4 more
20131 citations
Semantic Scholar
Beta-nicotinamide adenine dinucleotide (β-NAD) reverses the LPS-induced endothelial barrier dysfunction in sickle cell mice
N. S. Umapathy
20160 citations
Semantic Scholar
Therapeutic Potential of Beta-Nicotinamide Adenine Dinucleotide to Reverse Endothelial Barrier Dysfunction in Sickle Cell Mouse Model
N. S. Umapathy, Levi C Makala, Mayuko Takezaki, B. Pace
20150 citations
Semantic Scholar
Adenosine A1 Receptors Mediated Enhancement Of Barrier Function In Vasa Vasorum Endothelial Cells
N. S. Umapathy, E. Kaczmarek, R. Lucas, K. Stenmark +2 more
2012Asian Test Symposium0 citations
Semantic Scholar
The Effect Of Adenosine Compared To A2A Agonist, CGS 21680 In Wild Type Control And A2A Receptor (A2AR) Knock Out Murine Model Of Acute Lung Injury
J. Gonzales, Kyung Mi Kim, N. S. Umapathy, Matthew N Varn +2 more
2012Asian Test Symposium0 citations
Semantic Scholar
Growth Hormone Releasing Hormone Agonist Protects From Pneumolysin-Induced Pulmonary Permeability
R. Lucas, S. Sridhar, B. Gorshkov, Richard E. White +9 more
2012Asian Test Symposium0 citations
Semantic Scholar
Extracellular Beta Nicotinamide Adenine Dinucleotide (B-NAD) - Is This the Molecule to Treat Acute Lung Injury and Adult Respiratory Distress Syndrome
Pritam Neupane, S. Sridhar, R. Lucas, A. Verin +1 more
20110 citations
Semantic Scholar
Role Of Ethanol In Lung Endothelial Cell Barrier Permeability
N. S. Umapathy, A. Verin
2011Asian Test Symposium0 citations
Semantic Scholar
Beta Nicotinamide Adenine Dinucleotide (ß-NAD) Protects Lung Endothelial Cell Barrier Dysfunction In Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS)
J. Gonzales, B. Gorshkov, P. Biddinger, S. Black +2 more
2010Asian Test Symposium0 citations
Semantic Scholar
Extracellular Purines in Endothelial Cell Barrier Regulation
N. S. Umapathy, E. Zemskov, Agnieszka Jezierska, I. Kolosova +3 more
20100 citations
Semantic Scholar
P57: The differential expression of apical membrane transporters in colorectal cancer can be exploited for the targeted delivery of short chain fatty acid prodrugs
N. Gupta, N. S. Umapathy, P. Martin, Elangovan Gopal +5 more
20070 citations
Semantic Scholar
Proximity Assay for Measuring Membrane-Associated Steps of Peptidoglycan Biosynthesis in Escherichia coli
B. Chandrakala, B. Elias, U. Mehra, N. S. Umapathy +3 more
20010 citations
Semantic Scholar

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