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J. Ficorilli · SciRah

Researcher profile · Semantic Scholar

J. Ficorilli

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J. Ficorilli — researcher profile on SciRah

h-index: 20
Works: 31
Citations: 1,686

Most-cited papers

Lipid-based delivery systems for improving the bioavailability and lymphatic transport of a poorly water-soluble LTB4 inhibitor.
D. Hauss, S. Fogal, J. Ficorilli, C. A. Price +3 more
1998Journal of Pharmacy and Science340 citations
Semantic Scholar
Regulation of carbohydrate metabolism by the farnesoid X receptor.
K. R. Stayrook, K. Bramlett, R. Savkur, J. Ficorilli +4 more
2005Endocrinology297 citations
Semantic Scholar
Novel Small Molecule Glucagon-Like Peptide-1 Receptor Agonist Stimulates Insulin Secretion in Rodents and From Human Islets
K. Sloop, F. S. Willard, M. Brenner, J. Ficorilli +9 more
2010Diabetes141 citations Open access
Semantic Scholar
Regulation of GPR119 receptor activity with endocannabinoid-like lipids.
Samreen K. Syed, H. Bui, L. S. Beavers, Thomas B. Farb +6 more
2012American Journal of Physiology. Endocrinology and Metabolism117 citations
Semantic Scholar
Farnesoid X Receptor Agonist Reduces Serum Asymmetric Dimethylarginine Levels through Hepatic Dimethylarginine Dimethylaminohydrolase-1 Gene Regulation*
T. Hu, M. Chouinard, A. Cox, Philip Sipes +7 more
2006Journal of Biological Chemistry87 citations Open access
Semantic Scholar
Structural insights into probe-dependent positive allosterism of the GLP-1 receptor
A. Bueno, Bingfa Sun, F. S. Willard, D. Feng +15 more
2020Nature Chemical Biology81 citations
Semantic Scholar
Allosteric Modulation of Endogenous Metabolites as an Avenue for Drug Discovery
D. Wootten, E. Savage, C. Valant, Lauren T. May +6 more
2012Molecular Pharmacology76 citations
Semantic Scholar
The Discovery, Preclinical, and Early Clinical Development of Potent and Selective GPR40 Agonists for the Treatment of Type 2 Diabetes Mellitus (LY2881835, LY2922083, and LY2922470).
C. Hamdouchi, S. Kahl, Anjana Patel Lewis, Guemalli R. Cardona +25 more
2016Journal of Medicinal Chemistry56 citations Open access
Semantic Scholar
β-Cell Glucagon-Like Peptide-1 Receptor Contributes to Improved Glucose Tolerance After Vertical Sleeve Gastrectomy.
Darline Garibay, A. Mcgavigan, Seon-a Lee, J. Ficorilli +4 more
2016Endocrinology55 citations Open access
Semantic Scholar
Small Molecule Allosteric Modulation of the Glucagon-Like Peptide-1 Receptor Enhances the Insulinotropic Effect of Oxyntomodulin
F. S. Willard, D. Wootten, Aaron D. Showalter, E. Savage +8 more
2012Molecular Pharmacology55 citations
Semantic Scholar
Hepatic peroxisomal fatty acid β-oxidation is regulated by liver X receptor α
T. Hu, P. Foxworthy, Angela M. Siesky, J. Ficorilli +8 more
200553 citations Open access
Semantic Scholar
Positive Allosteric Modulation of the Glucagon-like Peptide-1 Receptor by Diverse Electrophiles*
A. Bueno, Aaron D. Showalter, D. Wainscott, C. Stutsman +5 more
2016Journal of Biological Chemistry51 citations Open access
Semantic Scholar
Inhibition of Deoxyhypusine Synthase Enhances Islet β Cell Function and Survival in the Setting of Endoplasmic Reticulum Stress and Type 2 Diabetes*
R. Robbins, S. Tersey, T. Ogihara, D. Gupta +5 more
2010Journal of Biological Chemistry49 citations Open access
Semantic Scholar
A Novel Humanized GLP-1 Receptor Model Enables Both Affinity Purification and Cre-LoxP Deletion of the Receptor
L. S. Jun, Aaron D. Showalter, N. Ali, F. Dai +6 more
2014PLoS ONE38 citations Open access
Semantic Scholar
Intra-islet glucagon confers β-cell glucose competence for first-phase insulin secretion and favors GLP-1R stimulation by exogenous glucagon
Over Cabrera, J. Ficorilli, J. Shaw, Felipe Echeverri +4 more
2021Journal of Biological Chemistry37 citations Open access
Semantic Scholar
Hepatic peroxisomal fatty acid beta-oxidation is regulated by liver X receptor alpha.
T. Hu, P. Foxworthy, Angela M. Siesky, J. Ficorilli +8 more
2005Endocrinology28 citations
Semantic Scholar
Ectonucleotidase NTPDase3 is abundant in pancreatic β-cells and regulates glucose-induced insulin secretion.
Samreen K. Syed, A. Kauffman, L. S. Beavers, J. Alston +7 more
2013American Journal of Physiology. Endocrinology and Metabolism27 citations
Semantic Scholar
A 15-ketosterol is a liver X receptor ligand that suppresses sterol-responsive element binding protein-2 activity1
R. Schmidt, J. Ficorilli, Youyan Zhang, K. Bramlett +11 more
2006Journal of Lipid Research22 citations Open access
Semantic Scholar
Catechol estrogens stimulate insulin secretion in pancreatic β-cells via activation of the transient receptor potential A1 (TRPA1) channel
Wenzhen Ma, Xingjuan Chen, R. Cerne, Samreen K. Syed +4 more
2018Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Chronic Collection of Mesenteric Lymph From Conscious, Tethered Rats.
D. Hauss, S. Fogal, J. Ficorilli
1998Contemporary topics in laboratory animal science21 citations
Semantic Scholar
Regulation of Endogenous (Male) Rodent GLP-1 Secretion and Human Islet Insulin Secretion by Antagonism of Somatostatin Receptor 5
Thomas B. Farb, M. Adeva, Thomas J. Beauchamp, Over Cabrera +17 more
2017Endocrinology20 citations
Semantic Scholar
Long-acting GIPR agonist LY3537021 reduces body weight and fasting blood glucose in patients with T2D: Preclinical development and phase 1 randomized ascending dose studies
William Roell, Jorge Alsina-Fernandez, Hongchang Qu, Tamer Coskun +12 more
2025Molecular Metabolism10 citations
Semantic Scholar
679-P: The Novel GIP, GLP-1, and Glucagon Triple Receptor Agonist LY3437943 Exhibits Robust Efficacy in Preclinical Models of Obesity and Diabetes
T. Coskun, J. Moyers, William Roell, Libbey S O'Farrell +13 more
2021Diabetes5 citations
Semantic Scholar
Correction: A Novel Humanized GLP-1 Receptor Model Enables Both Affinity Purification and Cre-LoxP Deletion of the Receptor
L. S. Jun, Aaron D. Showalter, N. Ali, F. Dai +6 more
2015PLoS ONE2 citations Open access
Semantic Scholar
Ectonucleotidase NTPDase 3 is abundant in pancreatic β cells and regulates 1 glucose induced insulin secretion
Samreen K. Syed, A. Kauffman, L. S. Beavers, J. Alston +7 more
20131 citations
Semantic Scholar
3042-LB: Residence Time (RT) of Insulin and C-Peptide Reveals Reversible vs. Treatment-Resistant ß-Cell Dysfunction in Female ZDF rats (fZDF) on High-Fat Diet (HFD)
Elizabeth J. Zanley, Valentina Pirro, Jill A. Willency, J. Ficorilli +3 more
2026Diabetes0 citations
Semantic Scholar
3040-LB: Preferential Secretion of Newly Synthesized Insulin from ß-Cells in fZDF Rats, by Stable Isotope Labeling and Kinetic Modeling, Is More Pronounced with Secretory Stress
Kelvin W. Li, Valentina Pirro, Jill A. Willency, J. Ficorilli +3 more
2026Diabetes0 citations
Semantic Scholar
2153-LB: Insulin and C-peptide Labeling Kinetics in Islets vs. Plasma of ZDF Rats
Elizabeth J. Zanley, Jill A. Willency, J. Ficorilli, K. Duffin +4 more
2025Diabetes0 citations
Semantic Scholar
Catechol estrogens stimulate insulin secretion in pancreatic β-cells via activation of the TRPA1 channel
Wenzhen Ma, Xingjuan Chen, R. Cerne, Samreen K. Syed +4 more
20180 citations
Semantic Scholar
for Drug Discovery □ S
D. Wootten, E. Savage, C. Valant, Lauren T. May +6 more
20120 citations
Semantic Scholar
Novel Small Molecule Glucagon-like Peptide-1 Receptor Agonist Stimulates Insulin Secretion in Rodents and from Human Islets Running Title : Novel GLP-1 Receptor Small Molecule Agonist
K. Sloop, F. S. Willard, M. Brenner, J. Ficorilli +9 more
20100 citations
Semantic Scholar

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