N. Blok

Most-cited papers

1. N-(fluorenyl-9-methoxycarbonyl) amino acids, a class of antiinflammatory agents with a different mechanism of action.

   Ronald M. Burch, Moshe Weitzberg, N. Blok, R. Muhlhauser +6 more

   1991Proceedings of the National Academy of Sciences of the United States of America107 citations Open access

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2. Discovery, modeling, and human pharmacokinetics of N-(2-acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl)thiophene-2-carboxamide (TBC3711), a second generation, ETA selective, and orally bioavailable endothelin antagonist.

   Cheng-De Wu, E. Decker, N. Blok, Huong Bui +8 more

   2004Journal of Medicinal Chemistry102 citations Open access

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3. Acyl substitution at the ortho position of anilides enhances oral bioavailability of thiophene sulfonamides: TBC3214, an ETA selective endothelin antagonist.

   Cheng-De Wu, E. Decker, N. Blok, Jian Li +9 more

   2001Journal of Medicinal Chemistry24 citations Open access

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4. Lipoarabinomannan enzyme-linked immunosorbent assay for early diagnosis of childhood tuberculous meningitis.

   N. Blok, D. Visser, R. Solomons, S. V. van Elsland +2 more

   2014The International Journal of Tuberculosis and Lung Disease21 citations

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5. Endothelin antagonists: substituted mesitylcarboxamides with high potency and selectivity for ET(A) receptors.

   Chen Wu, E. Decker, N. Blok, Huong Bui +12 more

   1999Journal of Medicinal Chemistry18 citations

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6. Erratum: N-(Fluorenyl-9-methoxy-carbonyl) amino acids, a class of antiinflammatory agents with a different mechanism of action (Proc. Natl. Acad. Sci. USA (January 1991) 88 (355-359))

   R. Burch, M. Weitzberg, N. Blok, R. Muhlhauser +11 more

   199111 citations

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7. SELECTIVE ALKYLATION/ACYLATION OF DI- OR TRIANIONS: EXPEDITIOUS DERIVATIZATION OF ENDOTHELIN ANTAGONISTS[1]

   Cheng-De Wu, N. Blok, Wen Li, G. Holland

   20021 citations

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8. Een vaste rust- en verblijfplaats op maat

   K. Jipping, N. Blok

   20140 citations

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9. Differential Susceptibility: Een moeilijk temperament als ontvankelijkheidsfactor in de relatie tussen opvoedingsstijl en gedrag.

   N. Blok

   20130 citations

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10. Selective Alkylation/Acylation of Di- or Trianions: Expeditious Derivatization of Endothelin Antagonists.

    Cheng-De Wu, N. Blok, Wen Li, G. Holland

    20100 citations

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11. Sulfonamides and their derivatives that modulate the activity of endothelin

    N. Blok, G. Holland, Cheng-De Wu

    20000 citations

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12. Sulfonamides for the treatment of disorders mediated by endothelin

    Cheng-Du Wu, N. Blok, T. Kogan, Karin M. Keller +1 more

    19980 citations

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13. Sulfamides pour le traitement des troubles induits par l'endotheline

    N. Blok, Karin Keller, Timothy P. Kogan, Patricia Woodard +1 more

    19980 citations

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14. Composes de sulfamides et sels pour le traitement des troubles induits par l'endotheline

    Chengde Wu, N. Blok, Timothy P. Kogan, Karin Keller +1 more

    19980 citations

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15. Sulfonamides and derivatives thereof that modulate the activity of laendotelina.

    N. Blok, T. Kogan, B. Raju, P. Woodard +1 more

    19970 citations

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