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M. Vanaerschot · SciRah

Researcher profile · Semantic Scholar

M. Vanaerschot

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M. Vanaerschot — researcher profile on SciRah

h-index: 34
Works: 67
Citations: 3,323

Most-cited papers

Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance.
Tim Downing, H. Imamura, Saskia Decuypere, T. Clark +16 more
2011Genome Research433 citations Open access
Semantic Scholar
Increasing failure of miltefosine in the treatment of Kala-azar in Nepal and the potential role of parasite drug resistance, reinfection, or noncompliance.
S. Rijal, B. Ostyn, S. Uranw, Keshav Rai +11 more
2013Clinical Infectious Diseases313 citations
Semantic Scholar
Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent
H. Imamura, Tim Downing, F. Van den Broeck, M. Sanders +29 more
2016eLife158 citations Open access
Semantic Scholar
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics
A. Cowell, E. Istvan, A. Lukens, M. G. Gomez-Lorenzo +40 more
2018Science133 citations Open access
Semantic Scholar
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials
Yevgeniya Antonova-Koch, Stephan Meister, Matthew Abraham, M. Luth +34 more
2018Science121 citations Open access
Semantic Scholar
Evaluation of Normalization Methods to Pave the Way Towards Large-Scale LC-MS-Based Metabolomics Profiling Experiments
B. Ejigu, D. Valkenborg, G. Baggerman, M. Vanaerschot +4 more
2013Omics115 citations Open access
Semantic Scholar
UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria
Christel Brunschwig, N. Lawrence, D. Taylor, E. Abay +44 more
2018Antimicrobial Agents and Chemotherapy97 citations Open access
Semantic Scholar
Molecular Mechanisms of Drug Resistance in Natural Leishmania Populations Vary with Genetic Background
Saskia Decuypere, M. Vanaerschot, K. Brunker, H. Imamura +5 more
2012PLoS Neglected Tropical Diseases96 citations Open access
Semantic Scholar
Combining Stage Specificity and Metabolomic Profiling to Advance Antimalarial Drug Discovery
James M. Murithi, Edward Owen, E. Istvan, Marcus C. S. Lee +7 more
2019Cell Chemical Biology87 citations Open access
Semantic Scholar
Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity
M. Vanaerschot, James M. Murithi, C. Pasaje, Sonja Ghidelli-Disse +27 more
2020Cell Chemical Biology79 citations Open access
Semantic Scholar
Linking In Vitro and In Vivo Survival of Clinical Leishmania donovani Strains
M. Vanaerschot, I. Maes, M. Ouakad, V. Adaui +6 more
2010PLoS ONE77 citations Open access
Semantic Scholar
Relapse after Treatment with Miltefosine for Visceral Leishmaniasis Is Associated with Increased Infectivity of the Infecting Leishmania donovani Strain
Keshav Rai, B. Cuypers, N. Bhattarai, S. Uranw +5 more
2013mBio74 citations Open access
Semantic Scholar
Antileishmanial Activity of a Series of N2,N4-Disubstituted Quinazoline-2,4-diamines
Kurt S. Van Horn, Xiao-Hua Zhu, T. Pandharkar, Sih-Yung Yang +8 more
2014Journal of Medicinal Chemistry69 citations Open access
Semantic Scholar
Treatment failure in leishmaniasis: drug-resistance or another (epi-) phenotype?
M. Vanaerschot, F. Dumetz, Syamal Roy, A. Ponte-Sucre +2 more
2014Expert Review of Anti-Infective Therapy69 citations
Semantic Scholar
Genomes of Leishmania parasites directly sequenced from patients with visceral leishmaniasis in the Indian subcontinent
M. Domagalska, H. Imamura, M. Sanders, F. Van den Broeck +9 more
2019bioRxiv63 citations Open access
Semantic Scholar
Metabolic adaptations of Leishmania donovani in relation to differentiation, drug resistance, and drug pressure
Maya Berg, M. Vanaerschot, A. Jankevics, B. Cuypers +8 more
2013Molecular Microbiology59 citations Open access
Semantic Scholar
Increased metacyclogenesis of antimony-resistant Leishmania donovani clinical lines
M. Ouakad, M. Vanaerschot, S. Rijal, Shyam Sundar +7 more
2011Parasitology59 citations Open access
Semantic Scholar
Detection of Leptomonas sp. parasites in clinical isolates of Kala-azar patients from India
P. Srivastava, V. Prajapati, M. Vanaerschot, G. Van der Auwera +2 more
2010Infection, Genetics and Evolution59 citations Open access
Semantic Scholar
Genome-wide SNP and microsatellite variation illuminate population-level epidemiology in the Leishmania donovani species complex
Tim Downing, Olivia Stark, M. Vanaerschot, H. Imamura +9 more
2012Infection, Genetics and Evolution57 citations Open access
Semantic Scholar
Antimonial Resistance in Leishmania donovani Is Associated with Increased In Vivo Parasite Burden
M. Vanaerschot, S. de Doncker, S. Rijal, L. Maes +2 more
2011PLoS ONE57 citations Open access
Semantic Scholar
Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention
R. Summers, C. Pasaje, J. P. Pisco, Josefine Striepen +30 more
2021Cell Chemical Biology55 citations Open access
Semantic Scholar
Treatment of Visceral Leishmaniasis: Model-Based Analyses on the Spread of Antimony-Resistant L. donovani in Bihar, India
Anette Stauch, H. Duerr, J. Dujardin, M. Vanaerschot +2 more
2012PLoS Neglected Tropical Diseases55 citations Open access
Semantic Scholar
Defining the Determinants of Specificity of Plasmodium Proteasome Inhibitors
Euna Yoo, Barbara H. Stokes, H. D. De Jong, M. Vanaerschot +9 more
2018Journal of the American Chemical Society54 citations Open access
Semantic Scholar
Hexahydroquinolines are Antimalarial Candidates with Potent Blood Stage and Transmission-Blocking Activity
M. Vanaerschot, L. Lucantoni, Tao Li, Jill M Combrinck +22 more
2017Nature Microbiology49 citations Open access
Semantic Scholar
Experimental Resistance to Drug Combinations in Leishmania donovani: Metabolic and Phenotypic Adaptations
Maya Berg, Raquel García-Hernández, B. Cuypers, M. Vanaerschot +6 more
2015Antimicrobial Agents and Chemotherapy48 citations Open access
Semantic Scholar
Drug resistance in vectorborne parasites: multiple actors and scenarios for an evolutionary arms race.
M. Vanaerschot, S. Huijben, F. Van den Broeck, J. Dujardin
2014FEMS Microbiology Reviews48 citations Open access
Semantic Scholar
Comparison of gene expression patterns among Leishmania braziliensis clinical isolates showing a different in vitro susceptibility to pentavalent antimony
V. Adaui, K. Schnorbusch, M. Zimić, A. Gutiérrez +8 more
2010Parasitology47 citations Open access
Semantic Scholar
LC-MS metabolomics from study design to data-analysis – using a versatile pathogen as a test case
Maya Berg, M. Vanaerschot, A. Jankevics, B. Cuypers +2 more
2013Computational and Structural Biotechnology Journal45 citations Open access
Semantic Scholar
In vitro susceptibility of Leishmania donovani to miltefosine in Indian visceral leishmaniasis.
V. Prajapati, Smriti Sharma, M. Rai, B. Ostyn +4 more
2013American Journal of Tropical Medicine and Hygiene43 citations Open access
Semantic Scholar
Drug-resistant microorganisms with a higher fitness – can medicines boost pathogens?
M. Vanaerschot, Saskia Decuypere, Maya Berg, Syamal Roy +1 more
2013Critical reviews in microbiology42 citations Open access
Semantic Scholar
Macromolecular biosynthetic parameters and metabolic profile in different life stages of Leishmania braziliensis: Amastigotes as a functionally less active stage
M. Jara, Maya Berg, G. Caljon, G. De Muylder +7 more
2017PLoS ONE39 citations Open access
Semantic Scholar
Complete Genome Sequence of a Novel Coronavirus (SARS-CoV-2) Isolate from Bangladesh
Senjuti Saha, R. Malaker, M. Sajib, M. Hasanuzzaman +14 more
2020Microbiology Resource Announcements37 citations Open access
Semantic Scholar
Probing the Open Global Health Chemical Diversity Library for Multistage-Active Starting Points for Next-Generation Antimalarials
Matthew Abraham, Kerstin Gagaring, Marisa L. Martino, M. Vanaerschot +12 more
2020ACS Infectious Diseases37 citations Open access
Semantic Scholar
Metagenomic Pathogen Sequencing in Resource-Scarce Settings: Lessons Learned and the Road Ahead
C. Yek, A. R. Pacheco, M. Vanaerschot, J. Bohl +8 more
2022Frontiers in Epidemiology36 citations Open access
Semantic Scholar
(Post-) Genomic approaches to tackle drug resistance in Leishmania
Maya Berg, An Mannaert, M. Vanaerschot, G. Van der Auwera +1 more
2013Parasitology34 citations Open access
Semantic Scholar
Multiplexed Spliced-Leader Sequencing: A high-throughput, selective method for RNA-seq in Trypanosomatids
B. Cuypers, M. Domagalska, P. Meysman, G. De Muylder +8 more
2017Scientific Reports31 citations Open access
Semantic Scholar
Comparative Gene Expression Analysis throughout the Life Cycle of Leishmania braziliensis: Diversity of Expression Profiles among Clinical Isolates
V. Adaui, D. Castillo, M. Zimić, A. Gutiérrez +10 more
2011PLoS Neglected Tropical Diseases28 citations Open access
Semantic Scholar
Single locus genotyping to track Leishmania donovani in the Indian subcontinent: Application in Nepal
Keshav Rai, N. Bhattarai, M. Vanaerschot, H. Imamura +8 more
2017PLoS Neglected Tropical Diseases27 citations Open access
Semantic Scholar
Alice in microbes' land: adaptations and counter-adaptations of vector-borne parasitic protozoa and their hosts.
G. Caljon, G. De Muylder, Lies Durnez, W. Jennes +2 more
2016FEMS Microbiology Reviews27 citations Open access
Semantic Scholar
The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance
James M. Murithi, Ioanna Deni, C. Pasaje, John Okombo +29 more
2021Cell Chemical Biology26 citations Open access
Semantic Scholar
Gene expression profiling of Leishmania (Leishmania) donovani: overcoming technical variation and exploiting biological variation
Saskia Decuypere, M. Vanaerschot, S. Rijal, Vanessa Yardley +4 more
2007Parasitology26 citations
Semantic Scholar
Estimation of secondary household attack rates for emergent SARS-CoV-2 variants detected by genomic surveillance at a community-based testing site in San Francisco
James Peng, S. Mann, Anthea M. Mitchell, Jamin Liu +26 more
2021medRxiv25 citations Open access
Semantic Scholar
Estimation of Secondary Household Attack Rates for Emergent Spike L452R Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variants Detected by Genomic Surveillance at a Community-Based Testing Site in San Francisco
James Peng, Jamin Liu, S. Mann, Anthea M. Mitchell +25 more
2021Clinical Infectious Diseases25 citations Open access
Semantic Scholar
Evaluation of whole genome amplification and bioinformatic methods for the characterization of Leishmania genomes at a single cell level
H. Imamura, P. Monsieurs, M. Jara, M. Sanders +6 more
2020Scientific Reports24 citations Open access
Semantic Scholar
Genetic markers for SSG resistance in Leishmania donovani and SSG treatment failure in visceral leishmaniasis patients of the Indian subcontinent.
M. Vanaerschot, Saskia Decuypere, Tim Downing, H. Imamura +13 more
2012Journal of Infectious Diseases24 citations Open access
Semantic Scholar
Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance
M. Luth, Karla P. Godinez-Macias, Daisy Chen, John Okombo +44 more
2024Science23 citations Open access
Semantic Scholar
Rapid deployment of SARS-CoV-2 testing: The CLIAHUB
Emily D. Crawford, Irene Acosta, V. Ahyong, Erika C. Anderson +182 more
2020PLoS Pathogens20 citations Open access
Semantic Scholar
Identification of a polymorphism in the N gene of SARS-CoV-2 that adversely impacts detection by a widely-used RT-PCR assay
M. Vanaerschot, S. Mann, James T. Webber, J. Kamm +23 more
2020bioRxiv16 citations Open access
Semantic Scholar
Genomic Epidemiology and Transmission Dynamics of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Congregate Healthcare Facilities in Santa Clara County, California
T. MacCannell, Joshua Batson, Brandon Bonin, K. Astha +57 more
2021Clinical Infectious Diseases11 citations Open access
Semantic Scholar
The antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957
Celia Miguel-Blanco, James M. Murithi, E. D. Benavente, Fiona Angrisano +15 more
2021Scientific Reports10 citations Open access
Semantic Scholar

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