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H. Vlaming · SciRah

Researcher profile · Semantic Scholar

H. Vlaming

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H. Vlaming — researcher profile on SciRah

h-index: 11
Works: 27
Citations: 530

Most-cited papers

The upstreams and downstreams of H3K79 methylation by DOT1L
H. Vlaming, F. van Leeuwen
2016Chromosoma103 citations
Semantic Scholar
Yeast PP4 Interacts with ATR Homolog Ddc2-Mec1 and Regulates Checkpoint Signaling
Nicole Hustedt, A. Seeber, R. Sack, Monika Tsai-Pflugfelder +9 more
2014Molecules and Cells69 citations Open access
Semantic Scholar
HDAC1 and HDAC2 collectively regulate intestinal stem cell homeostasis
C. Zimberlin, Cesare Lancini, Rachel Sno, S. Rosekrans +6 more
2015The FASEB Journal49 citations Open access
Semantic Scholar
Screening thousands of transcribed coding and non-coding regions reveals sequence determinants of RNA polymerase II elongation potential
H. Vlaming, Claudia A. Mimoso, A. Field, Benjamin J. E. Martin +1 more
2021Nature Structural & Molecular Biology47 citations Open access
Semantic Scholar
Flexibility in crosstalk between H2B ubiquitination and H3 methylation in vivo
H. Vlaming, T. Welsem, Erik L. Graaf, David Ontoso +4 more
2014EMBO Reports47 citations Open access
Semantic Scholar
The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8+ T cells
E. M. Kwesi-Maliepaard, M. A. Aslam, M. F. Alemdehy, T. van den Brand +13 more
2019Proceedings of the National Academy of Sciences of the United States of America43 citations Open access
Semantic Scholar
Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L‐dose dependency in HDAC1‐deficient thymic lymphoma
H. Vlaming, C. McLean, T. Korthout, M. F. Alemdehy +13 more
2019EMBO Journal35 citations Open access
Semantic Scholar
Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism
T. van Welsem, T. Korthout, Reggy Ekkebus, D. Morais +14 more
2018Nucleic Acids Research34 citations Open access
Semantic Scholar
Direct screening for chromatin status on DNA barcodes in yeast delineates the regulome of H3K79 methylation by Dot1
H. Vlaming, Thom M. Molenaar, T. van Welsem, D. W. Poramba-Liyanage +7 more
2016eLife27 citations Open access
Semantic Scholar
Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties
I. Stulemeijer, Dirk de Vos, Kirsten van Harten, O. Joshi +8 more
2015Scientific Reports24 citations Open access
Semantic Scholar
Crosstalk between aging and the epigenome.
H. Vlaming, F. van Leeuwen
2012Epigenomics14 citations
Semantic Scholar
Epigenetics Identifier screens reveal regulators of chromatin acylation and limited specificity of acylation antibodies
L. Kollenstart, Sophie C. van der Horst, Kees Vreeken, G. Janssen +5 more
2021Scientific Reports10 citations Open access
Semantic Scholar
Restrictor slows RNAPII elongation to promote termination at noncoding RNA loci
Claudia A. Mimoso, H. Vlaming, Nathalie P. de Wagenaar, Allison P Siegenfeld +1 more
2025Genes & Development6 citations Open access
Semantic Scholar
4 Flexibility in crosstalk between H 2 B ubiquitination and H 3 methylation in vivo
H. Vlaming, T. van Welsem, E. D. de Graaf, David Ontoso +5 more
20176 citations
Semantic Scholar
Flexibility in crosstalk between H2B ubiquitination and H3 methylation in vivo
H. Vlaming, T. Welsem, E. L. Graaf, David Ontoso +4 more
2014EMBO Reports4 citations Open access
Semantic Scholar
DOT1L inhibition does not modify the sensitivity of cutaneous T cell lymphoma to pan-HDAC inhibitors in vitro
E. M. Kwesi-Maliepaard, Muddassir Malik, T. van Welsem, R. van Doorn +4 more
2022Frontiers in Genetics3 citations Open access
Semantic Scholar
Strength is in engagement
Christine E. Cucinotta, Benjamin J E Martin, Melvin Noe-Gonzalez, P. Raman +2 more
2021EMBO Reports3 citations Open access
Semantic Scholar
Modeling Distributive Histone Modification by Dot1 Methyltransferases: From Mechanism to Biological Insights
D. Vos, H. Vlaming, Barbara M. Bakker, F. Leeuwen
20173 citations
Semantic Scholar
The H3K36me3 methyltransferase SETD2 contributes to PAF1C interactions with RNA Pol II and is required for neuronal differentiation
Christina Ambrosi, Ramon Pfaendler, Kristeli Eleftheriou, Stefan Butz +9 more
2026EMBO Journal1 citations Open access
Semantic Scholar
Restrictor slows early transcription elongation to render RNA polymerase II susceptible to termination at non-coding RNA loci
Claudia A. Mimoso, H. Vlaming, Nathalie P. de Wagenaar, Karen Adelman
2025bioRxiv1 citations Open access
Semantic Scholar
Evolutionarily-conserved chromatin crosstalk generates a DOT1L-dose dependency in thymic lymphoma caused by loss of HDAC1
H. Vlaming, C. McLean, T. Korthout, M. F. Alemdehy +13 more
2019bioRxiv0 citations Open access
Semantic Scholar
UvA-DARE ( Digital Academic Repository ) Connecting the dots
Dirk de Vos, H. Vlaming, Barbara M. Bakker, F. van Leeuwen
20170 citations
Semantic Scholar
Connecting the dots : Delineating the regulation of H3K79 methylation by Dot1
H. Vlaming
20170 citations
Semantic Scholar
Author response: Direct screening for chromatin status on DNA barcodes in yeast delineates the regulome of H3K79 methylation by Dot1
H. Vlaming, Thom M. Molenaar, T. van Welsem, D. W. Poramba-Liyanage +7 more
20160 citations Open access
Semantic Scholar
The upstreams and downstreams of H3K79 methylation by DOT1L
H. Vlaming, F. van Leeuwen
2016Chromosoma0 citations
Semantic Scholar
Principles of epigenetic inheritance
Sjoerd Hendriks, T. Korthout, Thom M. Molenaar, D. W. Poramba-Liyanage +4 more
20130 citations
Semantic Scholar
histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties
I. Stulemeijer, Dirk de Vos, Kirsten van Harten, O. Joshi +8 more
0 citations
Semantic Scholar

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