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Ju-Yi Hsieh · SciRah

Researcher profile · Semantic Scholar

Ju-Yi Hsieh

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Ju-Yi Hsieh — researcher profile on SciRah

h-index: 14
Works: 29
Citations: 536

Most-cited papers

Structural basis of antizyme-mediated regulation of polyamine homeostasis
Hsiang-Yi Wu, Shin-Fu Chen, Ju-Yi Hsieh, Fang-Yi Chou +11 more
2015Proceedings of the National Academy of Sciences of the United States of America78 citations Open access
Semantic Scholar
Specific roles for the Ccr4-Not complex subunits in expression of the genome.
Nowel Azzouz, O. Panasenko, C. Deluen, Ju-Yi Hsieh +2 more
2009RNA: A publication of the RNA Society70 citations Open access
Semantic Scholar
Determinants of the Dual Cofactor Specificity and Substrate Cooperativity of the Human Mitochondrial NAD(P)+-dependent Malic Enzyme
Ju-Yi Hsieh, Guang-Yaw Liu, G. Chang, Hui-Chih Hung
2006Journal of Biological Chemistry40 citations Open access
Semantic Scholar
Functional Roles of the Tetramer Organization of Malic Enzyme*
Ju-Yi Hsieh, Shaoj Chen, Hui-Chih Hung
2009Journal of Biological Chemistry36 citations Open access
Semantic Scholar
A small-molecule inhibitor suppresses the tumor-associated mitochondrial NAD(P)+-dependent malic enzyme (ME2) and induces cellular senescence
Ju-Yi Hsieh, Shao-Yu Li, Wen-Chen Tsai, Jyung-Hurng Liu +3 more
2015OncoTarget28 citations Open access
Semantic Scholar
Biochemical and Functional Characterization of Charge-defined Subfractions of High-density Lipoprotein From Normal Adults
Ju-Yi Hsieh, Chiz-Tzung Chang, Max T Huang, Chia-Ming Chang +7 more
2013Analytical Chemistry26 citations Open access
Semantic Scholar
Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration
Ju-Yi Hsieh, Kun-Chi Chen, Chun-Hsiung Wang, Guang-Yaw Liu +10 more
2023Communications Biology23 citations Open access
Semantic Scholar
Structural characteristics of the nonallosteric human cytosolic malic enzyme.
Ju-Yi Hsieh, Shao-Yu Li, Meng-Chun Chen, Pai-Chun Yang +4 more
2014Biochimica et Biophysica Acta23 citations
Semantic Scholar
Functional roles of ATP-binding residues in the catalytic site of human mitochondrial NAD(P)+-dependent malic enzyme.
Hui-Chih Hung, Yung-Ching Chien, Ju-Yi Hsieh, G. Chang +1 more
2005Biochemistry23 citations
Semantic Scholar
Electronegative Low-density Lipoprotein Increases Coronary Artery Disease Risk in Uremia Patients on Maintenance Hemodialysis
Chiz-Tzung Chang, Guei-Jane Wang, Chin-Chi Kuo, Ju-Yi Hsieh +9 more
2016Medicine21 citations Open access
Semantic Scholar
Functional Roles of Metabolic Intermediates in Regulating the Human Mitochondrial NAD(P)+-Dependent Malic Enzyme
Ju-Yi Hsieh, WanRou Shih, Yu-Hsuan Kuo, Guang-Yaw Liu +1 more
2019Scientific Reports19 citations Open access
Semantic Scholar
Minimal Antizyme Peptide Fully Functioning in the Binding and Inhibition of Ornithine Decarboxylase and Antizyme Inhibitor
Ju-Yi Hsieh, Jung-Yen Yang, Chih-Li Lin, Guang-Yaw Liu +1 more
2011PLoS ONE15 citations Open access
Semantic Scholar
Engineering of the Cofactor Specificities and Isoform-specific Inhibition of Malic Enzyme*
Ju-Yi Hsieh, Hui-Chih Hung
2009Journal of Biological Chemistry15 citations Open access
Semantic Scholar
Baicalein, 7,8-Dihydroxyflavone and Myricetin as Potent Inhibitors of Human Ornithine Decarboxylase
Yun-Chi Liu, Yi-Liang Liu, Ju-Yi Hsieh, Changlian Wang +3 more
2020Nutrients14 citations Open access
Semantic Scholar
Targeting human mitochondrial NAD(P)+-dependent malic enzyme (ME2) impairs energy metabolism and redox state and exhibits antileukemic activity in acute myeloid leukemia
Kun-Chi Chen, I-hsin Hsiao, Yu-Nan Huang, Yu-Tung Chou +6 more
2023Cellular Oncology13 citations Open access
Semantic Scholar
Influential factor contributing to the isoform‐specific inhibition by ATP of human mitochondrial NAD(P)+‐dependent malic enzyme
Ju-Yi Hsieh, Guang-Yaw Liu, Hui-Chih Hung
2008The FEBS Journal13 citations Open access
Semantic Scholar
Fumarate Analogs Act as Allosteric Inhibitors of the Human Mitochondrial NAD(P)+-Dependent Malic Enzyme
Ju-Yi Hsieh, Jyung-Hurng Liu, Pai-Chun Yang, Chi-Li Lin +2 more
2014PLoS ONE12 citations Open access
Semantic Scholar
Determinants of Nucleotide-Binding Selectivity of Malic Enzyme
Ju-Yi Hsieh, Meng-Chun Chen, Hui-Chih Hung
2011PLoS ONE12 citations Open access
Semantic Scholar
Functional role of fumarate site Glu59 involved in allosteric regulation and subunit–subunit interaction of human mitochondrial NAD(P)+‐dependent malic enzyme
Ju-Yi Hsieh, Yu-Hsiu Chiang, Kuan-Yu Chang, Hui-Chih Hung
2009The FEBS Journal11 citations Open access
Semantic Scholar
Increased electronegativity of high-density lipoprotein in uremia patients impairs its functional properties and is associated with the risk of coronary artery disease.
Chiz-Tzung Chang, Ming-Yi Shen, Ju-Yi Hsieh, Chia-Ming Chang +5 more
2018Atherosclerosis9 citations
Semantic Scholar
Long-range interaction between the enzyme active site and a distant allosteric site in the human mitochondrial NAD(P)+-dependent malic enzyme.
Ju-Yi Hsieh, Kuo-Liang Su, Pei-Tzu Ho, Hui-Chih Hung
2009Archives of Biochemistry and Biophysics8 citations
Semantic Scholar
Dual roles of Lys(57) at the dimer interface of human mitochondrial NAD(P)+-dependent malic enzyme.
Ju-Yi Hsieh, Jyung-Hurng Liu, Yi-Wen Fang, Hui-Chih Hung
2009Biochemical Journal7 citations
Semantic Scholar
Single nucleotide variants lead to dysregulation of the human mitochondrial NAD(P)+-dependent malic enzyme
Ju-Yi Hsieh, Hao Yang, S. Tewary, Hui Cheng +11 more
2021iScience6 citations Open access
Semantic Scholar
Citrullination negatively regulates the functions of the p53 protein and opposes its ubiquitination and degradation
Yi-Fang Yang, Chien-Yun Lee, Guang-Yaw Liu, Ju-Yi Hsieh +7 more
2025Proceedings of the National Academy of Sciences of the United States of America5 citations Open access
Semantic Scholar
Critical Factors in Human Antizymes that Determine the Differential Binding, Inhibition, and Degradation of Human Ornithine Decarboxylase
Ju-Yi Hsieh, Yen-Chin Liu, I. Cheng, Chu-Ju Lee +5 more
2019Biomolecules5 citations Open access
Semantic Scholar
Regulation of polyamine homeostasis through an antizyme citrullination pathway
Yi-Fang Yang, Chien-Yun Lee, Ju-Yi Hsieh, Yi-Liang Liu +3 more
2021Journal of Cellular Physiology4 citations
Semantic Scholar
Protein degradation of antizyme depends on the N‐terminal degrons
Ju-Yi Hsieh, Pui-Ying Leong, Yi-Fang Yang, Yi-Liang Liu +2 more
2024Protein Science1 citations
Semantic Scholar
Abstract 2121 AC1, a Natural Compound, Attenuates Triple-Negative Breast Cancer Cell Aggressiveness and Affects Ornithine Decarboxylase Expression and Activity
Oiti Kar, Ching-Wen Huang, Chih-Chia Lin, Ju-Yi Hsieh +1 more
2026Journal of Biological Chemistry0 citations Open access
Semantic Scholar
Corrigendum: Specific roles for the Ccr4-Not complex subunits in expression of the genome
Nowel Azzouz, O. Panasenko, C. Deluen, Ju-Yi Hsieh +2 more
2024RNA: A publication of the RNA Society0 citations
Semantic Scholar

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