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X. Xing · SciRah

Researcher profile · Semantic Scholar

X. Xing

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X. Xing — researcher profile on SciRah

h-index: 43
Works: 103
Citations: 5,636

Most-cited papers

Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms
Bing-Shan Li, L. Tsoi, W. Swindell, J. Gudjonsson +11 more
2014Journal of Investigative Dermatology382 citations Open access
Semantic Scholar
IL-1 and IL-36 are dominant cytokines in generalized pustular psoriasis
A. Johnston, X. Xing, Liza Wolterink, Drew H. Barnes +5 more
2016Journal of Allergy and Clinical Immunology327 citations Open access
Semantic Scholar
IL-1F5, F6, F8, and F9: a novel IL-1 family signaling system that is active in psoriasis and promotes keratinocyte antimicrobial peptide expression
A. Johnston, X. Xing, Andrew M. Guzman, Marybeth Riblett +10 more
2011Journal of Immunology323 citations Open access
Semantic Scholar
Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal derived interferon kappa
M. Sarkar, G. Hile, L. Tsoi, X. Xing +17 more
2018Annals of the Rheumatic Diseases254 citations Open access
Semantic Scholar
Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis
Fei-Yang Ma, O. Plazyo, A. Billi, L. Tsoi +24 more
2023Nature Communications251 citations Open access
Semantic Scholar
Genome-Wide Expression Profiling of Five Mouse Models Identifies Similarities and Differences with Human Psoriasis
W. Swindell, A. Johnston, Steve Carbajal, G. Han +13 more
2011PLoS ONE219 citations Open access
Semantic Scholar
Progression of acute-to-chronic atopic dermatitis is associated with quantitative rather than qualitative changes in cytokine responses
L. Tsoi, E. Rodriguez, D. Stölzl, U. Wehkamp +19 more
2019Journal of Allergy and Clinical Immunology195 citations Open access
Semantic Scholar
IFN-γ enhances cell-mediated cytotoxicity against keratinocytes via JAK2/STAT1 in lichen planus
S. Shao, L. Tsoi, M. Sarkar, X. Xing +16 more
2019Science Translational Medicine171 citations Open access
Semantic Scholar
Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis
W. Swindell, Kellie A. Michaels, A. Sutter, D. Diaconu +7 more
2017Genome Medicine170 citations Open access
Semantic Scholar
Contribution of plasma cells and B cells to hidradenitis suppurativa pathogenesis
J. Gudjonsson, L. Tsoi, Fei-Yang Ma, A. Billi +29 more
2020JCI Insight162 citations Open access
Semantic Scholar
Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms
Frank M. Davis, L. Tsoi, W. Melvin, A. denDekker +13 more
2021Journal of Experimental Medicine149 citations Open access
Semantic Scholar
The Histone Methyltransferase Setdb2 Modulates Macrophage Phenotype and Uric Acid Production in Diabetic Wound Repair
Andrew Kimball, Frank M. Davis, A. denDekker, Amrita D. Joshi +14 more
2019Immunity146 citations Open access
Semantic Scholar
Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair
C. Audu, W. Melvin, Amrita D. Joshi, S. Wolf +19 more
2022Cellular & Molecular Immunology142 citations Open access
Semantic Scholar
Evidence for altered Wnt signaling in psoriatic skin
J. Gudjonsson, A. Johnston, S. Stoll, Marybeth Riblett +7 more
2010Journal of Investigative Dermatology140 citations Open access
Semantic Scholar
Lupus skin is primed for IL-6 inflammatory responses through a keratinocyte-mediated autocrine type I interferon loop
J. Stannard, T. J. Reed, Emily M. Myers, L. Lowe +4 more
2016Journal of Investigative Dermatology132 citations Open access
Semantic Scholar
Non-lesional lupus skin contributes to inflammatory education of myeloid cells and primes for cutaneous inflammation
A. Billi, Fei-Yang Ma, O. Plazyo, M. Gharaee-Kermani +13 more
2022Science Translational Medicine127 citations Open access
Semantic Scholar
Robust shifts in S100a9 expression with aging: A novel mechanism for chronic inflammation
W. Swindell, A. Johnston, X. Xing, A. Little +4 more
2013Scientific Reports127 citations Open access
Semantic Scholar
TREM2 macrophages induced by human lipids drive inflammation in acne lesions
Tran H. Do, Fei-Yang Ma, P. Andrade, Rosane M. B. Teles +22 more
2022Science immunology120 citations Open access
Semantic Scholar
IFN-γ and TNF-α synergism may provide a link between psoriasis and inflammatory atherogenesis
N. Mehta, H. Teague, W. Swindell, Y. Baumer +17 more
2017Scientific Reports120 citations Open access
Semantic Scholar
VGLL3-regulated gene network as a promoter of sex biased autoimmune diseases
Yun Liang, L. Tsoi, X. Xing, M. Beamer +10 more
2016Nature Immunology114 citations Open access
Semantic Scholar
RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene Signature
W. Swindell, M. Beamer, M. Sarkar, S. Loftus +7 more
2018Frontiers in Immunology103 citations Open access
Semantic Scholar
Proteogenomic analysis of psoriasis reveals discordant and concordant changes in mRNA and protein abundance
W. Swindell, H. Remmer, M. Sarkar, X. Xing +7 more
2015Genome Medicine102 citations Open access
Semantic Scholar
Heterogeneity of Inflammatory and Cytokine Networks in Chronic Plaque Psoriasis
W. Swindell, X. Xing, P. Stuart, Cynthia S. Chen +6 more
2012PLoS ONE100 citations Open access
Semantic Scholar
MCPIP1/Regnase-1 restricts IL-17A- and IL-17C-dependent skin inflammation
L. Monin, J. Gudjonsson, E. Childs, Nilesh Amatya +8 more
2016Journal of Immunology72 citations Open access
Semantic Scholar
Single-cell transcriptomics reveals distinct effector profiles of infiltrating T cells in lupus skin and kidney
G. Dunlap, A. Billi, X. Xing, Fei-Yang Ma +7 more
2021bioRxiv71 citations Open access
Semantic Scholar
Inhibition of the Tumor Necrosis Factor-α Pathway Is Radioprotective for the Lung
Ming Zhang, J. Qian, X. Xing, F. Kong +3 more
2008Clinical Cancer Research69 citations Open access
Semantic Scholar
The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity.
A. Billi, M. Gharaee-Kermani, Joseph Fullmer, L. Tsoi +23 more
2019JCI Insight66 citations Open access
Semantic Scholar
Cross-disease transcriptomics: Unique IL-17A signaling in psoriasis lesions and an autoimmune PBMC signature
W. Swindell, M. Sarkar, Yun Liang, X. Xing +1 more
2016Journal of Investigative Dermatology66 citations Open access
Semantic Scholar
Phospholipase A2 enzymes represent a shared pathogenic pathway in psoriasis and pityriasis rubra pilaris
S. Shao, Jiao-Ling Chen, W. Swindell, L. Tsoi +16 more
2021JCI Insight65 citations Open access
Semantic Scholar
Molecular Profiling of Cutaneous Lupus Lesions Identifies Subgroups Distinct from Clinical Phenotypes
C. Berthier, L. Tsoi, T. J. Reed, J. Stannard +8 more
2019Journal of Clinical Medicine64 citations Open access
Semantic Scholar
Modulation of Epidermal Transcription Circuits in Psoriasis: New Links between Inflammation and Hyperproliferation
W. Swindell, A. Johnston, X. Xing, J. Voorhees +2 more
2013PLoS ONE64 citations Open access
Semantic Scholar
Hypersensitive interferon responses in lupus keratinocytes reveal key mechanistic determinants in cutaneous lupus
L. Tsoi, Grace A. Hile, C. Berthier, M. Sarkar +10 more
2019Journal of Immunology61 citations Open access
Semantic Scholar
Sebaceous gland atrophy in psoriasis: An explanation for psoriatic alopecia?
L. Rittié, T. Tejasvi, P. Harms, X. Xing +4 more
2016Journal of Investigative Dermatology60 citations Open access
Semantic Scholar
Differential cell composition and split epidermal differentiation in human palm, sole, and hip skin
J. Wiedemann, A. Billi, F. Bocci, Ghaidaa Kashgari +14 more
2023Cell Reports56 citations Open access
Semantic Scholar
STEAPs comprise a novel inflammatory nexus in pustular skin disorders
Yun Liang, X. Xing, M. Beamer, W. Swindell +7 more
2016Journal of Allergy and Clinical Immunology55 citations Open access
Semantic Scholar
IL-17 responses are the dominant inflammatory signal linking inverse, erythrodermic and chronic plaque psoriasis
X. Xing, Yun Liang, M. Sarkar, Liza Wolterink +6 more
2016Journal of Investigative Dermatology53 citations Open access
Semantic Scholar
Endogenous glucocorticoid deficiency in psoriasis promotes inflammation and abnormal differentiation
M. Sarkar, N. Kaplan, L. Tsoi, X. Xing +12 more
2017Journal of Investigative Dermatology51 citations Open access
Semantic Scholar
KLK6 expression in skin induces PAR1-mediated psoriasiform dermatitis and inflammatory joint disease.
A. Billi, J. Ludwig, Yi Fritz, R. Rozic +17 more
2020Journal of Clinical Investigation50 citations Open access
Semantic Scholar
Meta-Profiles of Gene Expression during Aging: Limited Similarities between Mouse and Human and an Unexpectedly Decreased Inflammatory Signature
W. Swindell, A. Johnston, Li-Ou Y. Sun, X. Xing +4 more
2012PLoS ONE47 citations Open access
Semantic Scholar
Single-cell Profiling of Prurigo Nodularis Demonstrates Prominent Immune-Stromal Crosstalk Driving Profibrotic Responses in COL11A1+ Fibroblasts and Reversal with Nemolizumab
F. Ma, M. Gharaee-Kermani, L. Tsoi, O. Plazyo +16 more
2023Journal of Allergy and Clinical Immunology46 citations Open access
Semantic Scholar
Susceptibility-associated genetic variation at IL12B enhances Th1 polarization in psoriasis.
A. Johnston, X. Xing, W. Swindell, James J. Kochkodan +7 more
2013Human Molecular Genetics46 citations Open access
Semantic Scholar
RNA-seq identifies a diminished differentiation gene signature in primary monolayer keratinocytes grown from lesional and uninvolved psoriatic skin
W. Swindell, M. Sarkar, Yun Liang, X. Xing +5 more
2017Scientific Reports44 citations Open access
Semantic Scholar
NextGen Sequencing Technology-based Dissection of Physiological Systems Integrative RNA-seq and microarray data analysis reveals GC content and gene length biases in the psoriasis transcriptome
W. Swindell, X. Xing, J. Voorhees, James T. Elder +2 more
201443 citations
Semantic Scholar
Single-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa
K. V. van Straalen, Feiyang Ma, P. Tsou, O. Plazyo +26 more
2023Journal of Clinical Investigation41 citations Open access
Semantic Scholar
Proprotein convertase subtilisin/kexin type 9 is a psoriasis-susceptibility locus that is negatively related to IL36G
A. Merleev, A. Ji-Xu, A. Toussi, L. Tsoi +16 more
2022JCI Insight40 citations Open access
Semantic Scholar
Epigenetic Regulation of TLR4 in Diabetic Macrophages Modulates Immunometabolism and Wound Repair
Frank M. Davis, A. denDekker, Andrew Kimball, Amrita D. Joshi +15 more
2020Journal of Immunology39 citations Open access
Semantic Scholar
Interleukin 6 regulates psoriasiform inflammation-associated thrombosis.
Yun-Mei Wang, J. Golden, Yi Fritz, Xiu-Fen Zhang +10 more
2016JCI Insight36 citations Open access
Semantic Scholar
Novel cytokine and chemokine markers of hidradenitis suppurativa reflect chronic inflammation and itch
A. R. Vossen, H. H. van der Zee, L. Tsoi, X. Xing +3 more
2018Allergy. European Journal of Allergy and Clinical Immunology28 citations Open access
Semantic Scholar
Non-invasive tape-stripping with high-resolution RNA profiling effectively captures a pre-inflammatory state in nonlesional psoriatic skin.
L. Tsoi, X. Xing, Enze Xing, R. Wasikowski +17 more
2021Journal of Investigative Dermatology25 citations Open access
Semantic Scholar
IFN-κ is critical for normal wound repair and is decreased in diabetic wounds
S. Wolf, C. Audu, Amrita D. Joshi, A. denDekker +10 more
2022JCI Insight24 citations Open access
Semantic Scholar

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