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G. Tachedjian · SciRah

Researcher profile · Semantic Scholar

G. Tachedjian

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G. Tachedjian — researcher profile on SciRah

h-index: 39
Works: 120
Citations: 5,536

Most-cited papers

The role of lactic acid production by probiotic Lactobacillus species in vaginal health.
G. Tachedjian, M. Aldunate, C. S. Bradshaw, R. Cone
2017Research in Microbiology478 citations Open access
Semantic Scholar
Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis
M. Aldunate, D. Srbinovski, A. Hearps, C. F. Latham +4 more
2015Frontiers in Physiology342 citations Open access
Semantic Scholar
Contraction of the type I IFN locus and unusual constitutive expression of IFN-α in bats
P. Zhou, M. Tachedjian, J. W. Wynne, V. Boyd +10 more
2016Proceedings of the National Academy of Sciences of the United States of America319 citations Open access
Semantic Scholar
The Evolving Facets of Bacterial Vaginosis: Implications for HIV Transmission
L. Mckinnon, S. Achilles, C. Bradshaw, Adam D. Burgener +14 more
2019AIDS Research and Human Retroviruses249 citations Open access
Semantic Scholar
Mechanisms of inhibition of HIV replication by non-nucleoside reverse transcriptase inhibitors.
N. Sluis-Cremer, G. Tachedjian
2008Virus Research189 citations Open access
Semantic Scholar
SPL7013 Gel (VivaGel®) Retains Potent HIV-1 and HSV-2 Inhibitory Activity following Vaginal Administration in Humans
C. Price, D. Tyssen, S. Sonza, Ashley Davie +9 more
2011PLoS ONE176 citations Open access
Semantic Scholar
N348I in the Connection Domain of HIV-1 Reverse Transcriptase Confers Zidovudine and Nevirapine Resistance
S. Yap, C. Sheen, Jonathan Fahey, Mark Zanin +7 more
2007PLoS Medicine176 citations Open access
Semantic Scholar
Vaginal concentrations of lactic acid potently inactivate HIV
M. Aldunate, D. Tyssen, Adam Johnson, Tasnim Zakir +4 more
2013Journal of Antimicrobial Chemotherapy173 citations Open access
Semantic Scholar
Structure Activity Relationship of Dendrimer Microbicides with Dual Action Antiviral Activity
D. Tyssen, S. Henderson, Adam Johnson, Jasminka Sterjovski +15 more
2010PLoS ONE168 citations Open access
Semantic Scholar
Decoding the Membrane Activity of the Cyclotide Kalata B1
S. Henriques, Yen-Hua Huang, K. Rosengren, Henri G. Franquelim +7 more
2011Journal of Biological Chemistry165 citations Open access
Semantic Scholar
Distinct Immune Responses Elicited From Cervicovaginal Epithelial Cells by Lactic Acid and Short Chain Fatty Acids Associated With Optimal and Non-optimal Vaginal Microbiota
D. Delgado-Diaz, D. Tyssen, Joshua A. Hayward, R. Gugasyan +2 more
2020Frontiers in Cellular and Infection Microbiology143 citations Open access
Semantic Scholar
Phosphatidylethanolamine Binding Is a Conserved Feature of Cyclotide-Membrane Interactions*
S. Henriques, Yen-Hua Huang, M. Castanho, L. Bagatolli +4 more
2012Journal of Biological Chemistry131 citations Open access
Semantic Scholar
Lactic acid from vaginal microbiota enhances cervicovaginal epithelial barrier integrity by promoting tight junction protein expression
D. Delgado-Diaz, Brianna Jesaveluk, Joshua A. Hayward, D. Tyssen +20 more
2022Microbiome119 citations Open access
Semantic Scholar
Potent Nonnucleoside Reverse Transcriptase Inhibitors Target HIV-1 Gag-Pol
A. Figueiredo, Katie L. Moore, J. Mak, N. Sluis-Cremer +2 more
2006PLoS Pathogens118 citations Open access
Semantic Scholar
The implausible “in vivo” role of hydrogen peroxide as an antimicrobial factor produced by vaginal microbiota
G. Tachedjian, D. O'Hanlon, J. Ravel
2018Microbiome107 citations Open access
Semantic Scholar
Virucidal Activity of the Dendrimer Microbicide SPL7013 Against HIV-1
S. Telwatte, Katie L. Moore, Adam Johnson, D. Tyssen +8 more
2011Antiviral Research98 citations Open access
Semantic Scholar
The packaging and maturation of the HIV-1 Pol proteins.
M. Hill, G. Tachedjian, J. Mak
2005Current HIV Research98 citations
Semantic Scholar
Anti-HIV-1 Activity of Lactic Acid in Human Cervicovaginal Fluid
D. Tyssen, Ying-Ying Wang, Joshua A. Hayward, P. Agius +6 more
2018Msphere82 citations Open access
Semantic Scholar
Maturation of the HIV reverse transcription complex: putting the jigsaw together
D. Warrilow, G. Tachedjian, D. Harrich
2009Reviews in Medical Virology67 citations
Semantic Scholar
Differential Evolution of Antiretroviral Restriction Factors in Pteropid Bats as Revealed by APOBEC3 Gene Complexity
Joshua A. Hayward, M. Tachedjian, Jie Cui, A. Cheng +5 more
2018Molecular biology and evolution64 citations Open access
Semantic Scholar
Identification of diverse groups of endogenous gammaretroviruses in mega- and microbats.
Jie Cui, G. Tachedjian, M. Tachedjian, E. Holmes +2 more
2012Journal of General Virology62 citations Open access
Semantic Scholar
Lactic acid-containing products for bacterial vaginosis and their impact on the vaginal microbiota: A systematic review
E. Plummer, C. Bradshaw, M. Doyle, C. Fairley +6 more
2021PLoS ONE60 citations Open access
Semantic Scholar
The NRTIs Lamivudine, Stavudine and Zidovudine Have Reduced HIV-1 Inhibitory Activity in Astrocytes
L. Gray, G. Tachedjian, Anne M. Ellett, Michael Roche +7 more
2013PLoS ONE59 citations Open access
Semantic Scholar
Discovery of Retroviral Homologs in Bats: Implications for the Origin of Mammalian Gammaretroviruses
Jie Cui, M. Tachedjian, Li-Na Wang, G. Tachedjian +2 more
2012Journal of Virology59 citations Open access
Semantic Scholar
Identification of diverse full-length endogenous betaretroviruses in megabats and microbats
Joshua A. Hayward, M. Tachedjian, Jie Cui, H. Field +3 more
2013Retrovirology58 citations Open access
Semantic Scholar
Mutations That Abrogate Human Immunodeficiency Virus Type 1 Reverse Transcriptase Dimerization Affect Maturation of the Reverse Transcriptase Heterodimer
J. Wapling, Katie L. Moore, S. Sonza, J. Mak +1 more
2005Journal of Virology58 citations Open access
Semantic Scholar
Efavirenz enhances the proteolytic processing of an HIV‐1 pol polyprotein precursor and reverse transcriptase homodimer formation
G. Tachedjian, Katie L. Moore, Stephen P. Goff, N. Sluis-Cremer
2005FEBS Letters57 citations Open access
Semantic Scholar
Antiretroviral compounds: mechanisms underlying failure of HAART to eradicate HIV-1.
M. Shehu-Xhilaga, G. Tachedjian, S. Crowe, K. Kedzierska
2005Current Medicinal Chemistry57 citations
Semantic Scholar
N348I in HIV-1 Reverse Transcriptase Decreases Susceptibility to Tenofovir and Etravirine in Combination with Other Resistance Mutations
N. Sluis-Cremer, Katie L. Moore, J. Radzio, S. Sonza +1 more
2010AIDS (London)49 citations Open access
Semantic Scholar
Host and Viral Proteins Modulating Ebola and Marburg Virus Egress
T. Gordon, Joshua A. Hayward, G. Marsh, M. Baker +1 more
2019Viruses44 citations Open access
Semantic Scholar
Infectious KoRV-related retroviruses circulating in Australian bats
Joshua A. Hayward, M. Tachedjian, C. Kohl, Adam Johnson +18 more
2020Proceedings of the National Academy of Sciences of the United States of America42 citations Open access
Semantic Scholar
Bats and Rodents Shape Mammalian Retroviral Phylogeny
Jie Cui, G. Tachedjian, Lin-Fa Wang
2015Scientific Reports39 citations Open access
Semantic Scholar
Evaluation of a low cost reverse transcriptase assay for plasma HIV-1 viral load monitoring.
V. Greengrass, Shannon Turnbull, J. Hocking, Amanda L. Dunne +3 more
2005Current HIV Research39 citations
Semantic Scholar
4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention
L. Maher, G. Tachedjian, Jennifer F. Hoy, I. Millwood +5 more
2007Medical Journal of Australia38 citations
Semantic Scholar
Favipiravir in early symptomatic COVID-19, a randomised placebo-controlled trial
J. Mcmahon, Jillian S. Y. Lau, Anna Coldham, J. Roney +29 more
2022EClinicalMedicine37 citations Open access
Semantic Scholar
The Effect of Exogenous Sex Steroids on the Vaginal Microbiota: A Systematic Review
Larissa K. Ratten, E. Plummer, C. Bradshaw, C. Fairley +6 more
2021Frontiers in Cellular and Infection Microbiology34 citations Open access
Semantic Scholar
HERV-K Gag RNA and Protein Levels Are Elevated in Malignant Regions of the Prostate in Males with Prostate Cancer
Simin D. Rezaei, Joshua A. Hayward, Sam Norden, J. Pedersen +3 more
2021Viruses33 citations Open access
Semantic Scholar
Dimerization of human immunodeficiency virus type 1 reverse transcriptase as an antiviral target.
S. Srivastava, N. Sluis-Cremer, G. Tachedjian
2006Current pharmaceutical design33 citations
Semantic Scholar
Unique Evolution of Antiviral Tetherin in Bats
Joshua A. Hayward, M. Tachedjian, Adam Johnson, Aaron T. Irving +9 more
2020bioRxiv31 citations Open access
Semantic Scholar
Sex is associated with the persistence of non‐optimal vaginal microbiota following treatment for bacterial vaginosis: a prospective cohort study
Larissa K. Ratten, E. Plummer, G. Murray, J. Danielewski +7 more
2020BJOG: an International Journal of Obstetrics and Gynaecology31 citations Open access
Semantic Scholar
Combined oral contraceptive pill-exposure alone does not reduce the risk of bacterial vaginosis recurrence in a pilot randomised controlled trial
L. Vodstrcil, E. Plummer, C. Fairley, G. Tachedjian +6 more
2019Scientific Reports31 citations Open access
Semantic Scholar
The Human Immunodeficiency Virus Type 1 Nonnucleoside Reverse Transcriptase Inhibitor Resistance Mutation I132M Confers Hypersensitivity to Nucleoside Analogs
Zandrea Ambrose, B. Herman, C. Sheen, Shannon Zelina +4 more
2009Journal of Virology30 citations Open access
Semantic Scholar
Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT.
D. Nissley, J. Radzio, Zandrea Ambrose, C. Sheen +4 more
2007Biochemical Journal30 citations Open access
Semantic Scholar
Molecular dissection of an inhibitor targeting the HIV integrase dependent preintegration complex nuclear import
K. Wagstaff, S. Headey, S. Telwatte, D. Tyssen +4 more
2018Cellular Microbiology29 citations Open access
Semantic Scholar
N348I in Reverse Transcriptase Provides a Genetic Pathway for HIV-1 to Select TAMs and Mutations Antagonistic to TAMs
J. Radzio, S. Yap, G. Tachedjian, N. Sluis-Cremer
2010AIDS (London)28 citations Open access
Semantic Scholar
Impact of residues in the nonnucleoside reverse transcriptase inhibitor binding pocket on HIV-1 reverse transcriptase heterodimer stability.
A. Figueiredo, Shannon Zelina, N. Sluis-Cremer, G. Tachedjian
2008Current HIV Research25 citations
Semantic Scholar
Sensitive Assessment of the Virologic Outcomes of Stopping and Restarting Non-Nucleoside Reverse Transcriptase Inhibitor-Based Antiretroviral Therapy
A. Geretti, Z. Fox, Jeffrey A. Johnson, C. Booth +8 more
2013PLoS ONE24 citations Open access
Semantic Scholar
Identification of mechanistically distinct inhibitors of HIV-1 reverse transcriptase through fragment screening
J. La, C. F. Latham, Ricky N Tinetti, Adam Johnson +7 more
2015Proceedings of the National Academy of Sciences of the United States of America23 citations Open access
Semantic Scholar
Mechanisms of HIV Transmission in Depo-Provera Users: The Likely Role of Hypoestrogenism
M. Hickey, Jennifer L. Marino, G. Tachedjian
201620 citations Open access
Semantic Scholar
Why Do We Need New Drug Classes for HIV Treatment and Prevention?
A. Waheed, G. Tachedjian
2016Current Topics in Medicinal Chemistry19 citations
Semantic Scholar

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N. Sluis-Cremer×11
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N. Sluis-Cremer — researcher profile on SciRah
D. Tyssen×10
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Joshua A. Hayward×9
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Lin-Fa Wang×8
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S. Sonza — researcher profile on SciRah

Adam Johnson×8

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Adam Johnson — researcher profile on SciRah

Katie L. Moore×8

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Katie L. Moore — researcher profile on SciRah

M. Tachedjian×7

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M. Tachedjian — researcher profile on SciRah

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A. Hearps — researcher profile on SciRah

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Jie Cui — researcher profile on SciRah

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M. Aldunate — researcher profile on SciRah

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R. Cone — researcher profile on SciRah