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S. Fricker · SciRah

Researcher profile · Semantic Scholar

S. Fricker

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S. Fricker — researcher profile on SciRah

h-index: 32
Works: 119
Citations: 5,813

Most-cited papers

CXCL12 (SDF-1)/CXCR4 Pathway in Cancer
B. Teicher, S. Fricker
2010Clinical Cancer Research1,371 citations Open access
Semantic Scholar
Multiple actions of the chemokine CXCL12 on epithelial tumor cells in human ovarian cancer.
C. Scotton, Julia L. Wilson, K. Scott, G. Stamp +4 more
2002Cancer Research512 citations
Semantic Scholar
The therapeutic application of lanthanides.
S. Fricker
2006Chemical Society Reviews423 citations
Semantic Scholar
Metal based drugs: from serendipity to design.
S. Fricker
2007Dalton Transactions370 citations
Semantic Scholar
Characterization of the molecular pharmacology of AMD3100: a specific antagonist of the G-protein coupled chemokine receptor, CXCR4.
S. Fricker, V. Anastassov, Jennifer Cox, M. Darkes +9 more
2006Biochemical Pharmacology228 citations
Semantic Scholar
AMD3100 mobilizes hematopoietic stem cells with long-term repopulating capacity in nonhuman primates.
A. Larochelle, Allen E. Krouse, M. Metzger, D. Orlic +5 more
2006Blood208 citations Open access
Semantic Scholar
Antitumor properties of some 2-[(dimethylamino)methyl]phenylgold(III) complexes.
R. Buckley, Amanda M. Elsome, S. Fricker, Graham R. Henderson +4 more
1996Journal of Medicinal Chemistry157 citations
Semantic Scholar
CXCR4 antagonists mobilize childhood acute lymphoblastic leukemia cells into the peripheral blood and inhibit engraftment
J. Juarez, A. D. Peña, Rana Baraz, J. Hewson +6 more
2007Leukemia141 citations Open access
Semantic Scholar
Metal compounds for the treatment of parasitic diseases.
S. Fricker, R. Mosi, B. Cameron, Ian R. Baird +13 more
2008Journal of Inorganic Biochemistry138 citations
Semantic Scholar
Chemical and Biological Studies of Dichloro(2-((dimethylamino)methyl)phenyl)gold(III).
R. Parish, B. P. Howe, J. Wright, J. Mack +4 more
1996Inorganic Chemistry138 citations
Semantic Scholar
Comparison of the Potential Multiple Binding Modes of Bicyclam, Monocylam, and Noncyclam Small-Molecule CXC Chemokine Receptor 4 Inhibitors
R. Wong, V. Bodart, Markus Metz, J. Labrecque +2 more
2008Molecular Pharmacology133 citations
Semantic Scholar
Cysteine proteases as targets for metal-based drugs.
S. Fricker
2010Metallomics130 citations
Semantic Scholar
Ruthenium complexes as nitric oxide scavengers: a potential therapeutic approach to nitric oxide‐mediated diseases
S. Fricker, E. Slade, N. A. Powell, O. J. Vaughan +5 more
1997British Journal of Pharmacology111 citations Open access
Semantic Scholar
Mobilization as a preparative regimen for hematopoietic stem cell transplantation.
J. Chen, A. Larochelle, S. Fricker, G. Bridger +2 more
2004Blood77 citations Open access
Semantic Scholar
Medicinal Organometallic Chemistry
S. Fricker
201174 citations Open access
Semantic Scholar
Durable engraftment of AMD3100-mobilized autologous and allogeneic peripheral-blood mononuclear cells in a canine transplantation model.
L. Burroughs, M. Mielcarek, M. Little, G. Bridger +5 more
2005Blood74 citations Open access
Semantic Scholar
Physiology and Pharmacology of Plerixafor
S. Fricker
2013Transfusion Medicine and Hemotherapy67 citations Open access
Semantic Scholar
Kinetics of nitric oxide scavenging by ruthenium(iii)polyaminocarboxylates: novel therapeutic agents for septic shock
N. Davies, Michael T. Wilson, E. Slade, S. Fricker +3 more
199762 citations
Semantic Scholar
Pharmacology of AMD3465: a small molecule antagonist of the chemokine receptor CXCR4.
V. Bodart, V. Anastassov, M. Darkes, Stefan R Idzan +13 more
2009Biochemical Pharmacology58 citations
Semantic Scholar
The in vitro antitumour profile of some 1,2-diaminocyclohexane organotin complexes.
Josiah J. Bonire, S. Fricker
2001Journal of Inorganic Biochemistry58 citations
Semantic Scholar
Ruthenium(III) polyaminocarboxylate complexes: efficient and effective nitric oxide scavengers.
B. Cameron, M. Darkes, Helen Yee, M. Olsen +7 more
2003Inorganic Chemistry56 citations
Semantic Scholar
Chemical and biological reactions of diacetato[2-(dimethylaminomethyl)-phenyl]gold(III), [Au(O2CMe)2(dmamp)]
R. Parish, J. Mack, L. Hargreaves, J. Wright +4 more
199651 citations
Semantic Scholar
The molecular pharmacology of AMD11070: an orally bioavailable CXCR4 HIV entry inhibitor.
R. Mosi, Virginia Anastassova, Jennifer Cox, M. Darkes +12 more
2012Biochemical Pharmacology50 citations
Semantic Scholar
Inhibition of the cathepsin cysteine proteases B and K by square-planar cycloaurated gold(III) compounds and investigation of their anti-cancer activity.
Yong-Bao Zhu, B. Cameron, R. Mosi, V. Anastassov +6 more
2011Journal of Inorganic Biochemistry50 citations
Semantic Scholar
CXCR4 in clinical hematology.
G. Calandra, G. Bridger, S. Fricker
2010Current Topics in Microbiology and Immunology45 citations
Semantic Scholar
Rhenium inhibitors of cathepsin B (ReO(SYS)X (where Y = S, py; X = Cl, Br, SPhOMe-p)): Synthesis and mechanism of inhibition.
R. Mosi, Ian R. Baird, Jennifer Cox, V. Anastassov +3 more
2006Journal of Medicinal Chemistry43 citations
Semantic Scholar
Metal complexes of bleomycin: evaluation of [Rh-105]-bleomycin for use in targeted radiotherapy.
R. Brooks, P. Carnochan, J. F. Vollano, N. A. Powell +6 more
1999Nuclear Medicine and Biology35 citations
Semantic Scholar
Medicinal chemistry and pharmacology of gold compounds
S. Fricker
199634 citations
Semantic Scholar
Ruthenium(III) triazacyclononane dithiocarbamate, pyridinecarboxylate, or aminocarboxylate complexes as scavengers of nitric oxide.
B. Cameron, M. Darkes, Ian R. Baird, R. Skerlj +2 more
2003Inorganic Chemistry33 citations
Semantic Scholar
Mechanistic studies on AMD6221: a ruthenium-based nitric oxide scavenger.
R. Mosi, B. Sēguin, B. Cameron, L. Amankwa +2 more
2002Biochemical and Biophysical Research Communications - BBRC32 citations
Semantic Scholar
HIV-1 entry inhibition by small-molecule CCR5 antagonists: a combined molecular modeling and mutant study using a high-throughput assay.
J. Labrecque, Markus Metz, Gloria H Y Lau, M. Darkes +10 more
2011Virology31 citations Open access
Semantic Scholar
AMD3465, a novel CXCR4 receptor antagonist, abrogates schistosomal antigen-elicited (type-2) pulmonary granuloma formation.
Jerry S. Hu, C. Freeman, V. Stolberg, Bo-Chin Chiu +4 more
2006American Journal of Pathology30 citations Open access
Semantic Scholar
Ruthenium as an effective nitric oxide scavenger.
C. Marmion, B. Cameron, C. Mulcahy, S. Fricker
2004Current Topics in Medicinal Chemistry30 citations
Semantic Scholar
A Ruthenium (III) Polyaminocarboxylate Complex, A Novel Nitric Oxide Scavenger, Enhances Graft Survival and Decreases Nitrosylated Heme Protein in Models of Acute and Delayed Cardiac Transplant Rejection
G. M. Pieper, A. Roza, M. Adams, Gail Hilton +7 more
2002Journal of Cardiovascular Pharmacology30 citations Open access
Semantic Scholar
The chemokine (C-X-C motif) receptor 4 inhibitor AMD3100 accelerates blood flow restoration in diabetic mice
C. Jiao, S. Fricker, G. Schatteman
2006Diabetologia26 citations Open access
Semantic Scholar
A Screening Strategy for Metal Antitumor Agents as Exemplified by Gold(III) Complexes
S. Fricker
1999Metal-Based Drugs25 citations Open access
Semantic Scholar
A novel CXCR4 antagonist for hematopoietic stem cell mobilization
S. Fricker
2008Expert Opinion on Investigational Drugs24 citations
Semantic Scholar
Increased matrix metalloproteinase activity after canine cardiopulmonary bypass is suppressed by a nitric oxide scavenger.
I. Mayers, T. Hurst, A. Radomski, David H. Johnson +5 more
2003Journal of Thoracic and Cardiovascular Surgery24 citations Open access
Semantic Scholar
Nitric oxide scavengers as a therapeutic approach to nitric oxide mediated disease.
S. Fricker
1999Expert Opinion on Investigational Drugs23 citations
Semantic Scholar
RuIII Complexes of Edta and Dtpa Polyaminocarboxylate Analogues and Their Use as Nitric Oxide Scavengers
T. Storr, B. Cameron, Robert A. Gossage, Helen Yee +8 more
200522 citations
Semantic Scholar
‘3 + 1’ mixed-ligand oxorhenium(V) complexes and their inhibition of the cysteine proteases cathepsin B and cathepsin K
Ian R. Baird, R. Mosi, M. Olsen, B. Cameron +2 more
200620 citations
Semantic Scholar
The ruthenium-based nitric oxide scavenger, AMD6221, augments cardiovascular responsiveness to noradrenaline in rats with streptozotocin-induced diabetes.
S. Hutchings, D. Song, S. Fricker, C. C. Pang
2005European Journal of Pharmacology18 citations
Semantic Scholar
Antitumor Actions of Ruthenium(III)-Based Nitric Oxide Scavengers and Nitric Oxide Synthase Inhibitors
F. W. Flitney, Rebecca J. Pritchard, G. D. Kennovin, S. Bisland +2 more
2011Molecular Cancer Therapeutics17 citations Open access
Semantic Scholar
A time-resolved fluorescent lanthanide (Eu)-GTP binding assay for chemokine receptors as targets in drug discovery.
J. Labrecque, R. Wong, S. Fricker
2009Methods in molecular biology17 citations
Semantic Scholar
The Development of an Europium-GTP Assay to Quantitate Chemokine Antagonist Interactions for CXCR4 and CCR5
J. Labrecque, V. Anastassov, Gloria H Y Lau, M. Darkes +2 more
2005Assay and drug development technologies17 citations
Semantic Scholar
Prospective CCR5 small molecule antagonist compound design using a combined mutagenesis/modeling approach.
Markus Metz, Élyse Bourque, J. Labrecque, S. Danthi +10 more
2011Journal of the American Chemical Society16 citations
Semantic Scholar
Strategies for the biological evaluation of gold anticancer agents.
S. Fricker
2011Anti-Cancer Agents in Medicinal Chemistry12 citations
Semantic Scholar
In vitro anti-HIV activity profile of AMD887, a novel CCR5 antagonist, in combination with the CXCR4 inhibitor AMD070
D. Schols, K. Vermeire, S. Hatse, K. Princen +9 more
200411 citations
Semantic Scholar
Macrophage-derived superoxide is not required for nitric oxide mediated tumour cell killing by RAW 264 cells.
S. Fricker, E. Slade, N. A. Powell
1999Anticancer Research11 citations
Semantic Scholar
Metal complexes as therapeutic agents in nitrogen monoxide modulation.
S. Fricker
2004Metal ions in biological systems10 citations
Semantic Scholar

Frequent co-authors

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G. Bridger×15
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G. Bridger — researcher profile on SciRah
M. Darkes×13
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B. Cameron×11
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R. Skerlj×11
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J. Labrecque — researcher profile on SciRah

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Gloria H Y Lau×7

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V. Anastassov×6

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Zefferino Santucci×6

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Jennifer Cox×5

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