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Shuen-Iu Hung · SciRah

Researcher profile · Semantic Scholar

Shuen-Iu Hung

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Shuen-Iu Hung — researcher profile on SciRah

h-index: 55
Works: 159
Citations: 12K

Most-cited papers

Carbamazepine-induced toxic effects and HLA-B*1502 screening in Taiwan.
Pei Chen, Juei-Jueng Lin, C. Lu, C. Ong +29 more
2011New England Journal of Medicine663 citations Open access
Semantic Scholar
Genetic variants associated with phenytoin-related severe cutaneous adverse reactions.
Wen-Hung Chung, Wan-Chun Chang, Yun-Shien Lee, Ying-Yi Wu +32 more
2014Journal of the American Medical Association (JAMA)280 citations
Semantic Scholar
Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome.
Chun-Yu Wei, Wen-Hung Chung, Hsiao-wen Huang, Yuan-Tsong Chen +1 more
2012Journal of Allergy and Clinical Immunology278 citations Open access
Semantic Scholar
HLA-A*31:01 and different types of carbamazepine-induced severe cutaneous adverse reactions: an international study and meta-analysis
E. Genin, D.-P. Chen, Shuen-Iu Hung, P. Sekula +14 more
2013The Pharmacogenomics Journal209 citations
Semantic Scholar
Evolving models of the immunopathogenesis of T-cell mediated drug allergy: the role of host, pathogens, and drug response
K. White, Wen-Hung Chung, Shuen-Iu Hung, S. Mallal +1 more
2015Journal of Allergy and Clinical Immunology203 citations Open access
Semantic Scholar
Randomized, controlled trial of TNF-&agr; antagonist in CTL-mediated severe cutaneous adverse reactions
Chuang-Wei Wang, Lan-Yan Yang, Chun-Bing Chen, H. Ho +15 more
2018Journal of Clinical Investigation190 citations Open access
Semantic Scholar
Insights into the poor prognosis of allopurinol-induced severe cutaneous adverse reactions: the impact of renal insufficiency, high plasma levels of oxypurinol and granulysin
Wen-Hung Chung, Wan-Chun Chang, S. Stocker, C. Juo +11 more
2014Annals of the Rheumatic Diseases184 citations
Semantic Scholar
Allopurinol Use and Risk of Fatal Hypersensitivity Reactions: A Nationwide Population-Based Study in Taiwan.
Chien-Yi Yang, Chi-Hua Chen, Shin‐Tarng Deng, Chi‐Shan Huang +5 more
2015JAMA Internal Medicine181 citations Open access
Semantic Scholar
SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation
K. White, R. Abe, M. Ardern-Jones, Thomas M. Beachkofsky +40 more
2018Journal of Allergy and Clinical Immunology: In Practice171 citations Open access
Semantic Scholar
Interleukin-15 Is Associated with Severity and Mortality in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis.
S. Su, M. Mockenhaupt, P. Wolkenstein, A. Dunant +12 more
2017Journal of Investigative Dermatology149 citations Open access
Semantic Scholar
An Updated Review of the Molecular Mechanisms in Drug Hypersensitivity
Chun-Bing Chen, R. Abe, Ren-You Pan, Chuang-Wei Wang +3 more
2018Journal of Immunological Research147 citations Open access
Semantic Scholar
Risk and association of HLA with oxcarbazepine-induced cutaneous adverse reactions in Asians
Chun-Bing Chen, Yi-Hsin Hsiao, Tony Wu, M. Hsih +34 more
2017Neurology120 citations
Semantic Scholar
Recent Development and Clinical Application of Cancer Vaccine: Targeting Neoantigens
Ren-You Pan, Wen-Hung Chung, Mu-Tzu Chu, Shu-Jen Chen +3 more
2018Journal of Immunological Research116 citations Open access
Semantic Scholar
Recent advances in the genetics and immunology of Stevens-Johnson syndrome and toxic epidermal necrosis.
Wen-Hung Chung, Shuen-Iu Hung
2012Journal of dermatological science (Amsterdam)109 citations
Semantic Scholar
Identification of drug-specific public TCR driving severe cutaneous adverse reactions
Ren-You Pan, Mu-Tzu Chu, Chuang-Wei Wang, Yun-Shien Lee +14 more
2019Nature Communications106 citations Open access
Semantic Scholar
Oxypurinol-Specific T Cells Possess Preferential TCR Clonotypes and Express Granulysin in Allopurinol-Induced Severe Cutaneous Adverse Reactions.
Wen-Hung Chung, Ren-You Pan, Mu-Tzu Chu, See-Wen Chin +4 more
2015Journal of Investigative Dermatology106 citations Open access
Semantic Scholar
Severe cutaneous adverse reactions related to systemic antibiotics.
Ying-Fang Lin, Chih-Hsun Yang, Hu Sindy, Jing-Yi Lin +9 more
2014Clinical Infectious Diseases101 citations Open access
Semantic Scholar
Impact of the HLA-B(*)58:01 Allele and Renal Impairment on Allopurinol-Induced Cutaneous Adverse Reactions.
C. Ng, Yu-Ting Yeh, Chuang-Wei Wang, Shuen-Iu Hung +12 more
2016Journal of Investigative Dermatology87 citations Open access
Semantic Scholar
Genotype-phenotype association between HLA and carbamazepine-induced hypersensitivity reactions: strength and clinical correlations.
Yi-Hsin Hsiao, R. Hui, Tony Wu, Wan-Chun Chang +11 more
2014Journal of dermatological science (Amsterdam)82 citations Open access
Semantic Scholar
A patch testing and cross‐sensitivity study of carbamazepine‐induced severe cutaneous adverse drug reactions
Yin-ku Lin, Ya-Ching Chang, R. Hui, C.-H. Yang +3 more
2013Journal of the European Academy of Dermatology and Venereology77 citations
Semantic Scholar
Clinicopathologic analysis of coxsackievirus a6 new variant induced widespread mucocutaneous bullous reactions mimicking severe cutaneous adverse reactions.
Wen-Hung Chung, Shin-Ru Shih, Ching-Fen Chang, Tzou-Yien Lin +14 more
2013Journal of Infectious Diseases72 citations Open access
Semantic Scholar
The Function of HLA-B*13:01 Involved in the Pathomechanism of Dapsone-Induced Severe Cutaneous Adverse Reactions.
Wei-Ti Chen, Chuang-Wei Wang, Chun-Wei Lu, Chun-Bing Chen +11 more
2018Journal of Investigative Dermatology68 citations Open access
Semantic Scholar
The Medication Risk of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis in Asians: The Major Drug Causality and Comparison With the US FDA Label
Yu-Hsin Wang, Chun-Bing Chen, W. Tassaneeyakul, Yoshiro Saito +34 more
2018Clinical pharmacology and therapy68 citations Open access
Semantic Scholar
HLA Alleles and CYP2C9*3 as Predictors of Phenytoin Hypersensitivity in East Asians
S. Su, Chun-Bing Chen, Wan-Chun Chang, Chuang-Wei Wang +18 more
2018Clinical pharmacology and therapy67 citations
Semantic Scholar
SJS/TEN 2019: From Science to Translation
Wan-Chun Chang, R. Abe, P. Anderson, Wanpen Anderson +66 more
2020Journal of dermatological science (Amsterdam)65 citations Open access
Semantic Scholar
Whole Genome Sequencing Identifies Genetic Variants Associated with Co-trimoxazole Hypersensitivity in Asians.
Chuang-Wei Wang, W. Tassaneeyakul, Chun-Bing Chen, Wei-Ti Chen +28 more
2020Journal of Allergy and Clinical Immunology64 citations
Semantic Scholar
HLA‐B*57:01 confers genetic susceptibility to carbamazepine‐induced SJS/TEN in Europeans
M. Mockenhaupt, Chuang-Wei Wang, Shuen-Iu Hung, P. Sekula +12 more
2019Allergy. European Journal of Allergy and Clinical Immunology63 citations Open access
Semantic Scholar
Genetic variants of PPAR-gamma coactivator 1B augment NLRP3-mediated inflammation in gouty arthritis
Wan-Chun Chang, Yeong-Jian Jan Wu, Wen-Hung Chung, Yun-Shien Lee +5 more
2016Rheumatology57 citations
Semantic Scholar
Rhein, An Anthraquinone Drug, Suppresses the NLRP3 Inflammasome and Macrophage Activation in Urate Crystal-Induced Gouty Inflammation.
Wan-Chun Chang, Mu-Tzu Chu, Chih-yen Hsu, Y. Wu +5 more
2019The American Journal of Chinese Medicine55 citations
Semantic Scholar
Pharmacogenetic Testing for Prevention of Severe Cutaneous Adverse Drug Reactions
Chih-Jung Chang, Chun-Bing Chen, Shuen-Iu Hung, Chao Ji +1 more
2020Frontiers in Pharmacology52 citations Open access
Semantic Scholar
A new nucleic acid-based agent inhibits cytotoxic T lymphocyte-mediated immune disorders.
Chuang-Wei Wang, Wen-Hung Chung, Yi-Fang Cheng, Nien-Wen Ying +3 more
2013Journal of Allergy and Clinical Immunology52 citations
Semantic Scholar
Hypersensitivity and Cardiovascular Risks Related to Allopurinol and Febuxostat Therapy in Asians: A Population‐Based Cohort Study and Meta‐Analysis
Chi-Hua Chen, Chun-Bing Chen, Chee-Jen Chang, Y. Lin +14 more
2019Clinical pharmacology and therapy49 citations
Semantic Scholar
Methotrexate‐induced epidermal necrosis: A case series of 24 patients
Ting-Jui Chen, Wen-Hung Chung, Chun-Bing Chen, R. Hui +6 more
2017Journal of American Academy of Dermatology45 citations
Semantic Scholar
Immunologic basis for allopurinol-induced severe cutaneous adverse reactions: HLA-B*58:01-restricted activation of drug-specific T cells and molecular interaction.
Chia-Hsien Lin, Jung-Kuei Chen, T. Ko, Chun-Yu Wei +6 more
2015Journal of Allergy and Clinical Immunology43 citations
Semantic Scholar
Severe Cutaneous Adverse Reactions: The Pharmacogenomics from Research to Clinical Implementation
S. Su, Shuen-Iu Hung, W. Fan, Ro-Lan Dao +1 more
2016International Journal of Molecular Sciences39 citations Open access
Semantic Scholar
Advances in understanding of the pathogenesis and therapeutic implications of drug reaction with eosinophilia and systemic symptoms: an updated review
Chun-Bing Chen, W. Hung, Chuang-Wei Wang, Chih-Chun Lee +2 more
2023Frontiers in Medicine37 citations Open access
Semantic Scholar
Pharmacogenomic Advances in the Prediction and Prevention of Cutaneous Idiosyncratic Drug Reactions
Ren-You Pan, Ro-Lan Dao, Shuen-Iu Hung, Wen-Hung Chung
2017Clinical pharmacology and therapy37 citations
Semantic Scholar
Updates in SJS/TEN: collaboration, innovation, and community
Madeline E Marks, Ramya Krishna Botta, Riichiro Abe, Thomas M. Beachkofsky +58 more
2023Frontiers in Medicine35 citations Open access
Semantic Scholar
Enhanced Antioxidant Capacity of Dental Pulp-Derived iPSC-Differentiated Hepatocytes and Liver Regeneration by Injectable HGF-Releasing Hydrogel in Fulminant Hepatic Failure
Chih-Hung Chiang, Wai-Wah Wu, Hsin-Yang Li, Yueh Chien +14 more
2015Cell Transplantation33 citations
Semantic Scholar
Detecting Lesional Granulysin Levels for Rapid Diagnosis of Cytotoxic T lymphocytes-mediated Bullous Skin Disorders.
Chun-Bing Chen, K. Kuo, Chuang-Wei Wang, Chun-Wei Lu +17 more
2020Journal of Allergy and Clinical Immunology: In Practice32 citations
Semantic Scholar
Delayed Drug Hypersensitivity Reactions: Molecular Recognition, Genetic Susceptibility, and Immune Mediators
Mu-Tzu Chu, Wan-Chun Chang, Shih-Cheng Pao, Shuen-Iu Hung
2023Biomedicines30 citations Open access
Semantic Scholar
Interferon α-inducible protein 27 is an oncogene and highly expressed in cholangiocarcinoma patients with poor survival
Kun-Chun Chiang, Sheng-Teng Huang, Ren-Chin Wu, Shih-Chiang Huang +10 more
2019Cancer Management and Research30 citations Open access
Semantic Scholar
Immune checkpoint inhibitor-induced severe epidermal necrolysis mediated by macrophage-derived CXCL10 and abated by TNF blockade
Chun-Bing Chen, Shuen-Iu Hung, John Wen-Cheng Chang, Chan-Keng Yang +28 more
2024Nature Communications29 citations
Semantic Scholar
The Roles of Immunoregulatory Networks in Severe Drug Hypersensitivity
Y. Hsu, Kun-Lin Lu, Yun Fu, Chuang-Wei Wang +7 more
2021Frontiers in Immunology29 citations Open access
Semantic Scholar
Stevens-Johnson syndrome and toxic epidermal necrolysis: risk factors, causality assessment and potential prevention strategies
Chu-Chi Lin, Chun-Bing Chen, Chuang-Wei Wang, Shuen-Iu Hung +1 more
2020Expert Review of Clinical Immunology27 citations
Semantic Scholar
Increased Type 2 Innate Lymphoid Cells in Patients with Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome.
Yi-Giien Tsai, J. Liou, Shuen-Iu Hung, Chun-Bing Chen +3 more
2019Journal of Investigative Dermatology27 citations Open access
Semantic Scholar
Fas/Fas ligand mediates keratinocyte death in sunitinib-induced hand-foot skin reaction.
Chun-Nan Yeh, Wen-Hung Chung, S. Su, Yen-Yang Chen +11 more
2014Journal of Investigative Dermatology27 citations Open access
Semantic Scholar
An update on CYP2C9 polymorphisms and phenytoin metabolism: implications for adverse effects
Wan-Chun Chang, Shuen-Iu Hung, B. Carleton, Wen-Hung Chung
2020Expert Opinion on Drug Metabolism & Toxicology24 citations
Semantic Scholar
The Role of Immune Checkpoint Receptors in Regulating Immune Reactivity in Lupus
Kun-Lin Lu, Ming-Ying Wu, Chi-Hui Wang, Chuang-Wei Wang +3 more
2019Cells24 citations Open access
Semantic Scholar
The skin as a metabolic and immune-competent organ: Implications for drug-induced skin rash
Amy M. Sharma, Yoshiro Saito, Shuen-Iu Hung, D. Naisbitt +2 more
2018Journal of Immunotoxicology23 citations Open access
Semantic Scholar

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Chun-Bing Chen×20
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Chuang-Wei Wang×19
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Wan-Chun Chang×13
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Chih-Hsun Yang×11

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Chun-Wei Lu×10

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Ya-Ching Chang×8

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