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Yuan-Tsong Chen · SciRah

Researcher profile · Semantic Scholar

Yuan-Tsong Chen

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Yuan-Tsong Chen — researcher profile on SciRah

h-index: 68
Works: 236
Citations: 21K

Most-cited papers

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
A. Mahajan, M. Go, Wei-Hua Zhang, J. Below +328 more
2014Nature Genetics1,020 citations Open access
Semantic Scholar
Carbamazepine-induced toxic effects and HLA-B*1502 screening in Taiwan.
Pei Chen, Juei-Jueng Lin, C. Lu, C. Ong +29 more
2011New England Journal of Medicine663 citations Open access
Semantic Scholar
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians
Y. Cho, Chien-Hsiun Chen, Cheng Hu, J. Long +62 more
2011Nature Genetics629 citations Open access
Semantic Scholar
Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians
N. Kato, F. Takeuchi, Y. Tabara, T. Kelly +45 more
2011Nature Genetics585 citations Open access
Semantic Scholar
PSORS2 is due to mutations in CARD14.
C. T. Jordan, Li Cao, E. Roberson, K. C. Pierson +15 more
2012American Journal of Human Genetics407 citations Open access
Semantic Scholar
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
N. Kato, M. Loh, F. Takeuchi, N. Verweij +240 more
2015Nature Genetics346 citations Open access
Semantic Scholar
Population structure of Han Chinese in the modern Taiwanese population based on 10,000 participants in the Taiwan Biobank project.
Chien-Hsiun Chen, Jenn-Hwai Yang, Charleston W. K. Chiang, Chia-Ni Hsiung +9 more
2016Human Molecular Genetics298 citations Open access
Semantic Scholar
Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations
Y. Okada, X. Sim, M. Go, Jer-yuarn Wu +42 more
2012Nature Genetics298 citations Open access
Semantic Scholar
Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese.
Shuen-Iu Hung, Wen-Hung Chung, Zhi-Sheng Liu, Chien-Hsiun Chen +4 more
2010Pharmacogenomics (London)297 citations
Semantic Scholar
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for HLA Genotype and Use of Carbamazepine and Oxcarbazepine: 2017 Update
E. Phillips, C. Sukasem, M. Whirl-Carrillo, D. Müller +10 more
2018Clinical pharmacology and therapy286 citations Open access
Semantic Scholar
Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome.
Chun-Yu Wei, Wen-Hung Chung, Hsiao-wen Huang, Yuan-Tsong Chen +1 more
2012Journal of Allergy and Clinical Immunology278 citations Open access
Semantic Scholar
Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome.
T. Ko, Wen-Hung Chung, Chun-Yu Wei, H. Shih +4 more
2011Journal of Allergy and Clinical Immunology261 citations Open access
Semantic Scholar
The impact of antibodies on clinical outcomes in diseases treated with therapeutic protein: Lessons learned from infantile Pompe disease
S. Banugaria, S. Prater, Y. Ng, J. Kobori +5 more
2011Genetics in Medicine248 citations Open access
Semantic Scholar
Measurement of Pre-Existing IgG and IgM Antibodies against Polyethylene Glycol in Healthy Individuals.
Bing-Mae Chen, Yu-Cheng Su, Chia-Jung Chang, Pierre-Alain Burnouf +6 more
2016Analytical Chemistry221 citations
Semantic Scholar
Genome-wide expression profiles of subchondral bone in osteoarthritis
Ching-Heng Chou, Chia-Chun Wu, I-Wen Song, Hui-Ping Chuang +8 more
2013Arthritis Research & Therapy131 citations Open access
Semantic Scholar
A Genome-Wide Association Study Reveals a Quantitative Trait Locus of Adiponectin on CDH13 That Predicts Cardiometabolic Outcomes
Chia-Min Chung, Tsung-Hsien Lin, Jaw-wen Chen, H. Leu +9 more
2011Diabetes125 citations Open access
Semantic Scholar
Interethnic analyses of blood pressure loci in populations of East Asian and European descent
F. Takeuchi, M. Akiyama, N. Matoba, T. Katsuya +193 more
2018Nature Communications109 citations Open access
Semantic Scholar
Identification of Novel Susceptibility Loci for Kawasaki Disease in a Han Chinese Population by a Genome-Wide Association Study
Fuu-Jen Tsai, Yi-Ching Lee, Jeng-Sheng Chang, Li-Min Huang +11 more
2011PLoS ONE100 citations Open access
Semantic Scholar
Pharmacogenomics of adverse drug reactions: implementing personalized medicine.
Chun-Yu Wei, M. Lee, Yuan-Tsong Chen
2012Human Molecular Genetics94 citations
Semantic Scholar
CXCL10/IP-10 is a biomarker and mediator for Kawasaki disease.
T. Ko, Ho-Chang Kuo, Jeng-Sheng Chang, Shih-Ping Chen +7 more
2015Circulation Research88 citations Open access
Semantic Scholar
Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference
W. Wen, N. Kato, Joo-Yeon Hwang, Xing-Yi Guo +72 more
2016Scientific Reports73 citations Open access
Semantic Scholar
Persistence of high sustained antibodies to enzyme replacement therapy despite extensive immunomodulatory therapy in an infant with Pompe disease: Need for agents to target antibody-secreting plasma cells
S. Banugaria, Trusha Patel, J. Mackey, Stuti Das +5 more
2012Molecular Genetics and Metabolism69 citations Open access
Semantic Scholar
Genome-wide analysis of copy number variations identifies PARK2 as a candidate gene for autism spectrum disorder
Chia-Lin Yin, Hsin-I Chen, Ling-Hui Li, Yi-Ling Chien +10 more
2016Molecular Autism68 citations Open access
Semantic Scholar
Genome-Wide Association Study of Treatment Refractory Schizophrenia in Han Chinese
Y. Liou, Hui-Hung Wang, M. Lee, Sheng-Chang Wang +19 more
2012PLoS ONE65 citations Open access
Semantic Scholar
A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol
Chia-Jung Chang, Chien-Hsiun Chen, Bing-Mae Chen, Yu-Cheng Su +7 more
2017Nature Communications61 citations Open access
Semantic Scholar
Loss of GPNMB Causes Autosomal-Recessive Amyloidosis Cutis Dyschromica in Humans.
Chi-Fan Yang, Shuan-Pei Lin, Chien-Ping Chiang, Yu-Hung Wu +4 more
2018American Journal of Human Genetics54 citations Open access
Semantic Scholar
Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.
F. V. van Rooij, R. Qayyum, A. Smith, Yi Zhou +96 more
2017American Journal of Human Genetics52 citations Open access
Semantic Scholar
A new nucleic acid-based agent inhibits cytotoxic T lymphocyte-mediated immune disorders.
Chuang-Wei Wang, Wen-Hung Chung, Yi-Fang Cheng, Nien-Wen Ying +3 more
2013Journal of Allergy and Clinical Immunology52 citations
Semantic Scholar
Identification of susceptibility gene associated with female primary Sjögren’s syndrome in Han Chinese by genome-wide association study
I-Wen Song, Hsian-Cheng Chen, Yuh-Feng Lin, Jenn-Hwai Yang +8 more
2016Human Genetics46 citations
Semantic Scholar
Association of circadian genes with diurnal blood pressure changes and non-dipper essential hypertension: a genetic association with young-onset hypertension
H. Leu, Chia-Min Chung, Shing-Jong Lin, Kuang-Mao Chiang +14 more
2014Hypertension Research46 citations Open access
Semantic Scholar
Identification of differentially expressed microRNAs in human hepatocellular adenoma associated with type I glycogen storage disease: a potential utility as biomarkers
Li-Ya Chiu, P. Kishnani, Tzu-Po Chuang, C. Tang +10 more
2014Journal of gastroenterology44 citations
Semantic Scholar
Replication of genome‐wide association signals of type 2 diabetes in Han Chinese in a prospective cohort
Yi-Cheng Chang, Yen-Feng Chiu, Pi-Hua Liu, K. Shih +9 more
2012Clinical Endocrinology44 citations
Semantic Scholar
Immunologic basis for allopurinol-induced severe cutaneous adverse reactions: HLA-B*58:01-restricted activation of drug-specific T cells and molecular interaction.
Chia-Hsien Lin, Jung-Kuei Chen, T. Ko, Chun-Yu Wei +6 more
2015Journal of Allergy and Clinical Immunology43 citations
Semantic Scholar
A recent update of pharmacogenomics in drug-induced severe skin reactions.
Chun-Yu Wei, T. Ko, Chen-Yang Shen, Yuan-Tsong Chen
2012Drug Metabolism and Pharmacokinetics43 citations
Semantic Scholar
Genome-wide association study identifies novel susceptibility loci for migraine in Han Chinese resided in Taiwan
Shih-Pin Chen, J. Fuh, M. Chung, Ying-Chao Lin +14 more
2018Cephalalgia42 citations
Semantic Scholar
Glycogen-branching enzyme deficiency leads to abnormal cardiac development: novel insights into glycogen storage disease IV.
Yi-Ching Lee, Chia-Jung Chang, D. Bali, Yuan-Tsong Chen +1 more
2011Human Molecular Genetics42 citations
Semantic Scholar
VarioWatch: providing large-scale and comprehensive annotations on human genomic variants in the next generation sequencing era
Yu-Chang Cheng, Fang-Chih Hsiao, Erh-Chan Yeh, Wan-Jia Lin +7 more
2012Nucleic Acids Res.41 citations Open access
Semantic Scholar
Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations.
J. Cornejo-García, L. Liou, N. Blanca-López, I. Doña +18 more
2013Pharmacogenomics (London)40 citations
Semantic Scholar
Knock-in human FGFR3 achondroplasia mutation as a mouse model for human skeletal dysplasia
Yi-Ching Lee, I-Wen Song, Ya-Ju Pai, Sheng Chen +1 more
2017Scientific Reports39 citations Open access
Semantic Scholar
Mouse model of glycogen storage disease type III.
Kai-Ming Liu, Jer-yuarn Wu, Yuan-Tsong Chen
2014Molecular Genetics and Metabolism39 citations
Semantic Scholar
Genome-wide transcriptome analysis to further understand neutrophil activation and lncRNA transcript profiles in Kawasaki disease
T. Ko, Jeng-Sheng Chang, Shih-Ping Chen, Yi-Min Liu +6 more
2019Scientific Reports36 citations Open access
Semantic Scholar
Association of an IGHV3-66 gene variant with Kawasaki disease
Todd A. Johnson, Y. Mashimo, Jer-yuarn Wu, Dankyu Yoon +26 more
2020Journal of Human Genetics34 citations Open access
Semantic Scholar
Pharmacogenomics for personalized pain medicine.
T. Ko, Chih-Shung Wong, Jer-yuarn Wu, Yuan-Tsong Chen
2016Acta Anaesthesiologica Taiwanica34 citations Open access
Semantic Scholar
Both IgM and IgG Antibodies against Polyethylene Glycol Can Alter the Biological Activity of Methoxy Polyethylene Glycol-Epoetin Beta in Mice
Tien-Ching Chang, Bing-Mae Chen, Wen-Wei Lin, Pei-Hua Yu +6 more
2019Pharmaceutics29 citations Open access
Semantic Scholar
Molecular profile and copy number analysis of sporadic colorectal cancer in Taiwan
Chien-Hsing Lin, Jen-Kou Lin, Shih-Ching Chang, Ya-Hui Chang +6 more
2011Journal of Biomedical Sciences29 citations Open access
Semantic Scholar
Antimicrobial Properties of an Immunomodulator - 15 kDa Human Granulysin
Hung-Mu Wei, Li-Chi Lin, Chiu-Feng Wang, Yi-Jang Lee +2 more
2016PLoS ONE26 citations Open access
Semantic Scholar
Loss of PTPRM Associates with the Pathogenic Development of Colorectal Adenoma-Carcinoma Sequence
Putty-Reddy Sudhir, Shiu-Ting Lin, C. Chien, Shung-Haur Yang +7 more
2015Scientific Reports24 citations Open access
Semantic Scholar
Palmitoyl acyltransferase activity of ZDHHC13 regulates skin barrier development partly by controlling PADi3 and TGM1 protein stability.
Li-Ying Chen, Kuo-Ray Lin, Yi-Ju Chen, Yun-Jung Chiang +9 more
2020Journal of Investigative Dermatology23 citations Open access
Semantic Scholar
Protein Palmitoylation by ZDHHC13 Protects Skin against Microbial-Driven Dermatitis.
Li-Ying Chen, H. Yang-Yen, Chun-Chou Tsai, C. L. Thio +10 more
2017Journal of Investigative Dermatology22 citations Open access
Semantic Scholar
Homozygosity Mapping and Whole-Genome Sequencing Links a Missense Mutation in POMGNT1 to Autosomal Recessive Retinitis Pigmentosa.
Na-Na-Hsiang-Hua Wang, Shih-Jen Chen, Chi-Fan Yang, Hui-Wen Chen +6 more
2016Investigative Ophthalmology and Visual Science22 citations Open access
Semantic Scholar

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