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J. Brugarolas · SciRah

Researcher profile · Semantic Scholar

J. Brugarolas

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J. Brugarolas — researcher profile on SciRah

h-index: 61
Works: 348
Citations: 18K

Most-cited papers

De novo and Salvage Purine Synthesis Pathways Across Tissues and Tumors
Diem H. Tran, Dohun Kim, Rushendhiran Kesavan, Harrison Brown +21 more
2024Cell189 citations Open access
Semantic Scholar
Stereotactic Ablative Radiation for Systemic Therapy Naïve Oligometastatic Kidney Cancer
R. Hannan, M. Christensen, A. Christie, A. Garant +14 more
2022European Urology Oncology63 citations Open access
Semantic Scholar
Glycosaminoglycan-driven lipoprotein uptake protects tumours from ferroptosis
Dylan Calhoon, Lingjie Sang, Fubo Ji, Divya Bezwada +26 more
2025Nature58 citations Open access
Semantic Scholar
An Oncogenic JMJD6-DGAT1 Axis Tunes Epigenetic Regulation of Lipid Droplet Formation in Clear Cell Renal Cell Carcinoma
Jin Zhou, Jeremy M. Simon, Cheng-Heng Liao, Cheng Zhang +15 more
2022Molecules and Cells56 citations Open access
Semantic Scholar
Phase 2 Trial of Stereotactic Ablative Radiotherapy for Patients with Primary Renal Cancer
R. Hannan, M. McLaughlin, Laurentiu M. Pop, I. Pedrosa +14 more
2023European Urology55 citations Open access
Semantic Scholar
In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma
Akash K. Kaushik, Amy Tarangelo, Lindsey K. Boroughs, Mukundan Ragavan +25 more
2022bioRxiv49 citations Open access
Semantic Scholar
Iterative refinement and goal articulation to optimize large language models for clinical information extraction
David Hein, A. Christie, Michael J. Holcomb, Bingqing Xie +9 more
2025npj Digital Medicine37 citations Open access
Semantic Scholar
An interdisciplinary consensus on the management of brain metastases in patients with renal cell carcinoma
E. Hasanov, D. Yeboa, Mathew D Tucker, T. Swanson +40 more
2022Ca37 citations Open access
Semantic Scholar
Recent Advances in Renal Tumors with TSC/mTOR Pathway Abnormalities in Patients with Tuberous Sclerosis Complex and in the Sporadic Setting
P. Kapur, J. Brugarolas, K. Trpkov
2023Cancers32 citations Open access
Semantic Scholar
Histopathology based AI model predicts anti-angiogenic therapy response in renal cancer clinical trial
Jay Jasti, Hua Zhong, Vandana Panwar, V. Jarmale +11 more
2025Nature Communications30 citations Open access
Semantic Scholar
GPR1 and CMKLR1 control lipid metabolism to support development of clear cell renal cell carcinoma
Da-Zhi Wang, Iqbal Mahmud, Vijay S. Thakur, S. K. Tan +8 more
2024Cancer Research28 citations Open access
Semantic Scholar
Molecular analysis of primary and metastatic sites in patients with renal cell carcinoma
Shuchi Gulati, Pedro C. Barata, A. Elliott, M. Bilen +17 more
2024Journal of Clinical Investigation28 citations Open access
Semantic Scholar
Metastatic renal cell carcinoma to the pancreas and other sites—a multicenter retrospective study
C. Duarte, Jun-Xiao Hu, B. Beuselinck, J. Panian +24 more
2023EClinicalMedicine26 citations Open access
Semantic Scholar
Facts and hopes for immunotherapy in renal cell carcinoma
C. Yao, Tian Zhang, Tuo-Qi Wu, J. Brugarolas
2022Clinical Cancer Research26 citations Open access
Semantic Scholar
Comparative genomics incorporating translocation renal cell carcinoma mouse model reveals molecular mechanisms of tumorigenesis
G. Prakasam, Akhilesh Mishra, A. Christie, Jeffrey Miyata +20 more
2024Journal of Clinical Investigation23 citations Open access
Semantic Scholar
RNA Polymerase II partitioning is a shared feature of diverse oncofusion condensates
Heankel Lyons, Prashant Pradhan, G. Prakasam, Shubham Vashishtha +12 more
2025Cell22 citations Open access
Semantic Scholar
A First-in-Human Phase 1 Study of a Tumor-Directed RNA-Interference Drug against HIF2α in Patients with Advanced Clear Cell Renal Cell Carcinoma
J. Brugarolas, Gregory Obara, Kathryn E. Beckermann, B. Rini +8 more
2024Clinical Cancer Research20 citations Open access
Semantic Scholar
ImmunoPET Imaging with 89Zr-labeled Atezolizumab Enables In Vivo Evaluation of PD-L1 in Tumorgraft Models of Renal Cell Carcinoma
Aditi Mulgaonkar, Roy Elias, Layton Woolford, B. Guan +10 more
2022Clinical Cancer Research20 citations Open access
Semantic Scholar
PML restrains p53 activity and cellular senescence in clear cell renal cell carcinoma
Matilde Simoni, Chiara Menegazzi, Cristina Fracassi, Claudia C Biffi +8 more
2024EMBO Molecular Medicine14 citations Open access
Semantic Scholar
Predicting Oncologic Outcomes in Small Renal Tumors
P. Kapur, Hua Zhong, Ellen Araj, A. Christie +9 more
2022European Urology Oncology14 citations Open access
Semantic Scholar
Molecular underpinnings of dedifferentiation and aggressiveness in chromophobe renal cell carcinoma
P. Kapur, Hua Zhong, Daniel Le, R. Mukhopadhyay +7 more
2024JCI Insight13 citations Open access
Semantic Scholar
HIF2 inactivation and tumor suppression with a tumor-directed RNA-silencing drug in mice and humans
Yuanqing Ma, Allison Joyce, Olivia Brandenburg, Faeze Saatchi +25 more
2022Clinical Cancer Research13 citations Open access
Semantic Scholar
A Call for a Neoadjuvant Kidney Cancer Consortium: Lessons Learned from Other Cancer Types.
A. Bex, M. Jewett, Bryan Lewis, E. J. Abel +31 more
2025European Urology12 citations
Semantic Scholar
Copper Drives Remodeling of Metabolic State and Progression of Clear Cell Renal Cell Carcinoma
Megan E. Bischoff, Behrouz Shamsaei, Jue-Chen Yang, D. Secic +22 more
2024Cancer Discovery11 citations Open access
Semantic Scholar
Endogenous Targeting of Lipid Nanoparticles to Kidney Tumors
Amogh Vaidya, Yun-Chieh Sung, Vanina Toffessi Tcheuyap, Cheng-Cheng Zhang +16 more
2025ACS Nano10 citations
Semantic Scholar
Determinants of late metastases in renal cell carcinoma.
P. Kapur, Hua Zhong, A. Christie, Hai-Tao Xu +13 more
2025Journal of the National Cancer Institute10 citations Open access
Semantic Scholar
Pathological Response and Outcomes in Patients With Metastatic Renal Cell Carcinoma (mRCC) Receiving Immunotherapy-Based Therapies and Undergoing Deferred Cytoreductive Nephrectomy (CN)
D. Gunenc, W. Issa, Thomas Gerald, Qinhan Zhou +15 more
2024Clinical Genitourinary Cancer10 citations Open access
Semantic Scholar
BBOX1 restrains TBK1-mTORC1 oncogenic signaling in clear cell renal cell carcinoma
Cheng-Heng Liao, Lian-Xin Hu, L. Jia, Jin Zhou +19 more
2025Nature Communications9 citations Open access
Semantic Scholar
Kinome-wide siRNA Screen Identifies a DCLK2-TBK1 Oncogenic Signaling Axis in Clear Cell Renal Cell Carcinoma
Lian-Xin Hu, Yan-Feng Zhang, Lei Guo, Hua Zhong +21 more
2024Molecules and Cells9 citations Open access
Semantic Scholar
MorphoITH: a framework for deconvolving intra-tumor heterogeneity using tissue morphology
A. W. Nielsen, H. E. Manoochehri, Hua Zhong, Vandana Panwar +7 more
2025Genome Medicine8 citations Open access
Semantic Scholar
Histopathology Based AI Model Predicts Anti-Angiogenic Therapy Response in Renal Cancer Clinical Trial
Jay Jasti, Hua Zhong, Vandana Panwar, V. Jarmale +11 more
2024arXiv.org8 citations
Semantic Scholar
Reporting on FH-deficient renal cell carcinoma using circulating succinylated metabolites
Divya Bezwada, J. Brugarolas
2023Journal of Clinical Investigation8 citations Open access
Semantic Scholar
Adrenal Insufficiency following Stereotactic Ablative Radiotherapy (SAbR) of Adrenal Gland Metastases
O. Hamidi, M. Miljanic, G. Tumyan, A. Christie +7 more
2024Cancers7 citations Open access
Semantic Scholar
An ultraconserved snoRNA-like element in long noncoding RNA CRNDE promotes ribosome biogenesis and cell proliferation
Jong-Sun Lee, T. Dan, He Zhang, Yujing Cheng +3 more
2024bioRxiv7 citations Open access
Semantic Scholar
Phase III randomized trial of stereotactic ablative radiotherapy (SAbR) for oligometastatic advanced renal carcinoma (EA8211-SOAR).
R. Hannan, S. Kim, S. Cole, E. Wulff-Burchfield +12 more
2024Journal of Clinical Oncology7 citations
Semantic Scholar
Characteristics and Outcomes of T1a Renal Cell Carcinoma Presenting with Metastasis
Luke Wang, Melis Guer, Dhruv Puri, Franklin Liu +12 more
2023Cancers7 citations Open access
Semantic Scholar
Navigating and adapting care integrating immunotherapy, antiangiogenic therapy, and combinations in patients with advanced renal cell carcinoma
B. Rini, J. Brugarolas, M. Atkins
2023Journal for ImmunoTherapy of Cancer7 citations Open access
Semantic Scholar
Prompts to Table: Specification and Iterative Refinement for Clinical Information Extraction with Large Language Models
David Hein, A. Christie, Michael J. Holcomb, Bingqing Xie +9 more
2025medRxiv6 citations Open access
Semantic Scholar
HIF-2-dependent Regulation of PTHrP and Paraneoplastic Hypercalcemia in Aggressive Clear Cell Renal Cell Carcinoma
A. Mal, Bingqing Xie, Zane N. Gray, C. Small +18 more
2025Cancer Discovery5 citations
Semantic Scholar
Systemic Treatment of Locally Advanced or Metastatic Non-Clear Cell Renal Cell Carcinoma
J. Vento, Tian Zhang, P. Kapur, H. Hammers +2 more
2025Cancers5 citations
Semantic Scholar
Predictive Factors for Oligometastatic Renal Cell Carcinoma Treated with Stereotactic Radiation: A Retrospective Study.
Allen Yen, Shanshan Tang, A. Christie, J. Kwon +9 more
2025European Urology Oncology4 citations
Semantic Scholar
An ultraconserved snoRNA-like element in long noncoding RNA CRNDE promotes ribosome biogenesis and cell proliferation
Jong-Sun Lee, T. Dan, He Zhang, Yujing Cheng +3 more
2025Molecules and Cells4 citations Open access
Semantic Scholar
A multimodal ensemble approach for clear cell renal cell carcinoma treatment outcome prediction
Meixu Chen, Kai Wang, P. Kapur, J. Brugarolas +2 more
2024arXiv.org4 citations
Semantic Scholar
Lactate-Activated GPR132 Signaling Drives a Tumor Microenvironmental Autocrine Metabolic Loop in Kidney Cancer.
Da-Zhi Wang, Timothy M Horton, Kyutae D. Lee, I. Ogobuiro +17 more
2026Cancer Research3 citations
Semantic Scholar
Stereotactic Radiation for Systemic Therapy-naïve Oligometastatic Kidney Cancer: Final Results of a Phase 2b Trial.
R. Hannan, R. Assadi, A. Christie, V. Puliyadi +9 more
2026European Urology Oncology2 citations
Semantic Scholar
Stereotactic Ablative Radiotherapy for Oligoprogressive Metastatic RCC: Predictors of Prolonged Systemic Therapy Benefit.
Lucian Zhao, D. Keilty, Soumyajit Roy, Tidie Song +13 more
2026International Journal of Radiation Oncology, Biology, Physics2 citations
Semantic Scholar
International Society of Urological Pathology Consensus on Cancer Precursor Lesions: Working Group 3 Preneoplastic and Precursor Lesions of the Kidney.
Sean R. Williamson, Sara E. Wobker, Rohit Mehra, Khaleel I. Al-Obaidy +15 more
2026American Journal of Surgical Pathology2 citations
Semantic Scholar
Determinants of pancreatic tropism in metastatic renal cell carcinoma
Haitao Xu, P. Kapur, A. Christie, A. W. Nielsen +23 more
2026JCI Insight2 citations Open access
Semantic Scholar
Comparative analysis of patient-derived organoids and patient-derived xenografts as avatar models for predicting response to anti-cancer therapy
J. M. Romero, Jamie Magrill, N. Kalashnikov, Yi Luo +49 more
2025medRxiv2 citations
Semantic Scholar
Stereotactic Radiation Therapy for the Treatment of Glandular Metastases From Renal Cell Carcinoma
M. Miljanic, Tidie Song, A. Christie, Allen Yen +10 more
2025Advances in Radiation Oncology2 citations Open access
Semantic Scholar

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