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O. Kabbarah · SciRah

Researcher profile · Semantic Scholar

O. Kabbarah

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O. Kabbarah — researcher profile on SciRah

h-index: 20
Works: 59
Citations: 2,501

Most-cited papers

Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers
R. Maser, B. Choudhury, P. Campbell, Bin Feng +32 more
2007Nature418 citations Open access
Semantic Scholar
GOLPH3 modulates mTOR signaling and rapamycin sensitivity in cancer
Kenneth L. Scott, O. Kabbarah, Mei-Chih Liang, E. Ivanova +15 more
2009Nature359 citations Open access
Semantic Scholar
Mutational Analysis of Patients With Colorectal Cancer in CALGB/SWOG 80405 Identifies New Roles of Microsatellite Instability and Tumor Mutational Burden for Patient Outcome.
F. Innocenti, F. Ou, X. Qu, T. Zemla +12 more
2019Journal of Clinical Oncology276 citations Open access
Semantic Scholar
Integrative Genome Comparison of Primary and Metastatic Melanomas
O. Kabbarah, C. Nogueira, Bin Feng, R. Nazarian +13 more
2010PLoS ONE216 citations Open access
Semantic Scholar
Impact of Consensus Molecular Subtype on Survival in Patients With Metastatic Colorectal Cancer: Results From CALGB/SWOG 80405 (Alliance).
H. Lenz, F. Ou, A. Venook, H. Hochster +11 more
2019Journal of Clinical Oncology205 citations Open access
Semantic Scholar
A transcriptional MAPK Pathway Activity Score (MPAS) is a clinically relevant biomarker in multiple cancer types
Marie-Claire Wagle, Daniel C. Kirouac, C. Klijn, Bonnie Liu +19 more
2018npj Precision Oncology168 citations Open access
Semantic Scholar
Integrated genomic analysis of colorectal cancer progression reveals activation of EGFR through demethylation of the EREG promoter
X. Qu, T. Sandmann, H. Frierson, L. Fu +15 more
2016Oncogene75 citations Open access
Semantic Scholar
Antibody–drug conjugates: an emerging modality for the treatment of cancer
M. Leal, P. Sapra, S. Hurvitz, P. Senter +5 more
2014Annals of the New York Academy of Sciences72 citations
Semantic Scholar
Impact of consensus molecular subtyping (CMS) on overall survival (OS) and progression free survival (PFS) in patients (pts) with metastatic colorectal cancer (mCRC): Analysis of CALGB/SWOG 80405 (Alliance).
H. Lenz, F. Ou, A. Venook, H. Hochster +9 more
201771 citations
Semantic Scholar
Phase I Study of DSTP3086S, an Antibody-Drug Conjugate Targeting Six-Transmembrane Epithelial Antigen of Prostate 1, in Metastatic Castration-Resistant Prostate Cancer.
D. Danila, R. Szmulewitz, U. Vaishampayan, C. Higano +11 more
2019Journal of Clinical Oncology70 citations Open access
Semantic Scholar
Genomic landscape of metastatic colorectal cancer
J. Haan, M. Labots, C. Rausch, M. Koopman +15 more
2014Nature Communications68 citations Open access
Semantic Scholar
Primary (1°) tumor location as an independent prognostic marker from molecular features for overall survival (OS) in patients (pts) with metastatic colorectal cancer (mCRC): Analysis of CALGB / SWOG 80405 (Alliance).
A. Venook, F. Ou, H. Lenz, O. Kabbarah +11 more
201763 citations
Semantic Scholar
A Clinically Applicable Gene-Expression Classifier Reveals Intrinsic and Extrinsic Contributions to Consensus Molecular Subtypes in Primary and Metastatic Colon Cancer
R. Piskol, L. Huw, Ismail Sergin, Christiaan Kljin +14 more
2019Clinical Cancer Research48 citations Open access
Semantic Scholar
Revealing the genomic heterogeneity of melanoma.
O. Kabbarah, L. Chin
2005Cancer Cell47 citations Open access
Semantic Scholar
ARID1A mutations confer intrinsic and acquired resistance to cetuximab treatment in colorectal cancer
Radia M. Johnson, X. Qu, Chu-Fang Lin, L. Huw +15 more
2022Nature Communications37 citations Open access
Semantic Scholar
A panel of repeat markers for detection of microsatellite instability in murine tumors
O. Kabbarah, Mary Ann Mallon, J. Pfeifer, W. Edelmann +2 more
2003Molecular Carcinogenesis33 citations
Semantic Scholar
Expression profiling of mouse endometrial cancers microdissected from ethanol-fixed, paraffin-embedded tissues.
O. Kabbarah, K. Pinto, D. Mutch, P. Goodfellow
2003American Journal of Pathology31 citations Open access
Semantic Scholar
621 A Phase I Dose-escalation Study of MFGR1877S, a Human Monoclonal Anti-fibroblast Growth Factor Receptor 3 (FGFR3) Antibody, in Patients (pts) with Advanced Solid Tumors
P. Odonnell, J. Goldman, M. Gordon, K. Shih +6 more
201228 citations
Semantic Scholar
Phase I study of the anti-endothelin B receptor antibody-drug conjugate DEDN6526A in patients with metastatic or unresectable cutaneous, mucosal, or uveal melanoma
S. Sandhu, C. McNeil, P. LoRusso, M. Patel +12 more
2019Investigational new drugs26 citations
Semantic Scholar
Somatic DNA mutations, MSI status, mutational load (ML): Association with overall survival (OS) in patients (pts) with metastatic colorectal cancer (mCRC) of CALGB/SWOG 80405 (Alliance).
F. Innocenti, F. Ou, T. Zemla, D. Niedzwiecki +12 more
201724 citations
Semantic Scholar
HER2 Gene Expression Levels Are Predictive and Prognostic in Patients With Metastatic Colorectal Cancer Enrolled in CALGB/SWOG 80405
F. Battaglin, F. Ou, X. Qu, H. Hochster +10 more
2024Journal of Clinical Oncology17 citations Open access
Semantic Scholar
A phase I study of DSTP3086S, an antibody-drug conjugate (ADC) targeting STEAP-1, in patients (pts) with metastatic castration-resistant prostate cancer (CRPC).
D. Danila, R. Szmulewitz, A. Baron, C. Higano +9 more
201417 citations
Semantic Scholar
A phase I study of the safety and pharmacokinetics of DSTP3086S, an anti-STEAP1 antibody-drug conjugate (ADC), in patients (pts) with metastatic castration-resistant prostate cancer (CRPC).
D. Danila, R. Szmulewitz, C. Higano, H. Gilbert +8 more
201317 citations
Semantic Scholar
CD47-blocking Antibody ZL-1201 Promotes Tumor-associated Macrophage Phagocytic Activity and Enhances the Efficacy of the Therapeutic Antibodies and Chemotherapy
Anthony T. Cao, Jiaqing Yi, Xinyan Tang, C. Szeto +12 more
2022Cancer Research Communications12 citations Open access
Semantic Scholar
Advances in malignant melanoma: genetic insights from mouse and man.
O. Kabbarah, L. Chin
2006Frontiers in Bioscience12 citations Open access
Semantic Scholar
DNA Mutational Profiling in Patients With Colorectal Cancer Treated With Standard of Care Reveals Differences in Outcome and Racial Distribution of Mutations
Federico Innocenti, Wan-Cen Mu, X. Qu, F. Ou +5 more
2023Journal of Clinical Oncology11 citations Open access
Semantic Scholar
ZL-1211 Exhibits Robust Antitumor Activity by Enhancing ADCC and Activating NK Cell–mediated Inflammation in CLDN18.2-High and -Low Expressing Gastric Cancer Models
Hiroyasu Konno, Tracey Lin, Ren-Yi Wu, Xin-Chuan Dai +17 more
2022Cancer Research Communications11 citations Open access
Semantic Scholar
Transcriptional profiling endometrial carcinomas microdissected from DES‐treated mice identifies changes in gene expression associated with estrogenic tumor promotion
O. Kabbarah, M. A. Mallon, J. Pfeifer, P. Goodfellow
2006International Journal of Cancer11 citations Open access
Semantic Scholar
Diethylstilbestrol effects and lymphomagenesis in Mlh1‐deficient mice
O. Kabbarah, Andrea Kathleen Sotelo, M. A. Mallon, Erin L. Winkeler +5 more
2005International Journal of Cancer10 citations Open access
Semantic Scholar
Tumor immunogenomic features determine outcomes in metastatic colorectal cancer patients treated with standard-of-care combinations of bevacizumab and cetuximab
F. Innocenti, A. Yazdani, N. Rashid, X. Qu +8 more
2022Clinical Cancer Research8 citations Open access
Semantic Scholar
Peer Review #1 of "Identification of differentially expressed methylated genes in melanoma versus nevi using bioinformatics methods (v0.1)"
Cong-Cong He, Yu-Jing Zhang, Hang-Hang Jiang, Xue-Li Niu +82 more
20208 citations Open access
Semantic Scholar
Abstract CT233: A first-in-human phase I study of the safety and pharmacokinetic (PK) activity of DEDN6526A, an anti-endothelin B receptor (ETBR) antibody-drug conjugate (ADC), in patients with metastatic or unresectable melanoma
J. Infante, S. Sandhu, C. McNeil, O. Kabbarah +6 more
20148 citations
Semantic Scholar
Next-generation sequencing (NGS) in metastatic colorectal cancer (mCRC): Novel mutated genes and their effect on response to therapy (Alliance)
F. Innocenti, N. Rashid, M. Wancen, F. Ou +7 more
2019Annals of Oncology6 citations Open access
Semantic Scholar
Transcriptomic profiling of adjuvant colorectal cancer identifies three key prognostic biological processes and a disease specific role for granzyme B
A. Daemen, Akshata R. Udyavar, T. Sandmann, Congfen Li +10 more
2021PLoS ONE4 citations Open access
Semantic Scholar
Predictive and prognostic value of HER2 gene expression and HER2 amplification in patients with metastatic colorectal cancer (mCRC) enrolled in CALGB/SWOG 80405 (Alliance).
F. Battaglin, F. Ou, X. Qu, M. Bertagnolli +10 more
20204 citations
Semantic Scholar
STEAP1 as a predictive biomarker for antibody-drug conjugate (ADC) activity in metastatic castration resistant prostate cancer (mCRPC).
D. Danila, M. Fleisher, J. Carrasquillo, H. Gilbert +16 more
20154 citations
Semantic Scholar
Abstract LB-063: ARID1A mutations induce an EGFR-like gene expression signature and confer intrinsic and acquired resistance to cetuximab treatment in first line metastatic CRC
Radia M. Johnson, X. Qu, Joshua Thomas, Yvonne T. Kschonsak +13 more
2020Bioinformatics, Convergence Science, and Systems Biology2 citations
Semantic Scholar
Prognostic stromal and immune response expression patterns in early-stage colorectal cancer predicted by genes intrinsically expressed by tumor epithelial cells.
P. Wirapati, X. Qu, L. Huw, E. Etlioglu +2 more
2019Journal of Clinical Oncology2 citations
Semantic Scholar
Predictive value of MAOB gene expression for targeted therapy in patients (pts) with metastatic colorectal cancer (mCRC) enrolled in CALGB (Alliance)/SWOG 80405.
Wu Zhang, J. Millstein, Yan Yang, F. Ou +16 more
2022Journal of Clinical Oncology1 citations
Semantic Scholar
Abstract 1203: ZL-1211 exhibits broad anti-tumor activity in CLDN18.2 high- and low-expressing models
Hiroyasu Konno, Yong Li, X. Dai, Bee-Chun Sun +16 more
2021Experimental and Molecular Therapeutics1 citations
Semantic Scholar
Abstract P6-03-24: ORIC-101 robustly inhibits the glucocorticoid pathway and overcomes chemoresistance in triple-negative breast cancer
Hai-Ying Zhou, Qiu-Ping Ye, A. Pankov, Wayne Kong +4 more
20201 citations
Semantic Scholar
Abstract 4120: ORIC-101 comprehensively inhibits glucocorticoid pathways to overcome therapeutic resistance in pan-cancer models
A. Pankov, Hai-Ying Zhou, S. Barkund, G. Hegde +4 more
2020Experimental and Molecular Therapeutics1 citations
Semantic Scholar
Abstract 4121: ORIC-101 overcomes resistance to diverse chemotherapeutics across cancer types
Hai-Ying Zhou, S. Barkund, A. Pankov, G. Hegde +6 more
2020Experimental and Molecular Therapeutics1 citations
Semantic Scholar
Development and Application of a Microfluidics-Based Panel in the Basal/Luminal Transcriptional Characterization of Archival Bladder Cancers
Doris Kim, Younjeong Choi, J. Ireland, O. Foreman +13 more
2016PLoS ONE1 citations Open access
Semantic Scholar
Abstract #3775: Mechanistic studies of AV370, a potent FGFR3 antagonistic antibody
Ai-Lin Bai, W. Winston, K. Meetze, Sriram Kollipara +13 more
20091 citations
Semantic Scholar
Abstract 3425: The CD47-targeting antibody ZL-1201 enhances anti-tumor activity of standard of care therapeutic antibodies by promoting phagocytosis in hematologic and solid tumor models
A. Cao, Jiaqing Yi, Ren-Yi Wu, C. Szeto +5 more
2022Cancer Research0 citations
Semantic Scholar
Abstract 621: ZL-1211 exhibits robust anti-tumor activity by enhancing ADCC and activating innate and adaptive immunity in CLDN18.2-high and -low expressing gastric cancer models
Hiroyasu Konno, Tracey Lin, Bee-Chun Sun, Ren-Yi Wu +4 more
2022Cancer Research0 citations
Semantic Scholar
Abstract 498: ZL-1201, a differentiated CD47 therapeutic antibody with improved hematological safety profile
B. Wan, Xu Fang, Shou Li, Wenhua Shi +14 more
2021Clinical research0 citations
Semantic Scholar
Immune signatures to affect overall survival (OS) and response to bevacizumab (Bev) or cetuximab (Cet) in patients (pts) with metastatic colorectal cancer (mCRC) of CALGB/SWOG 80405 (Alliance).
F. Innocenti, A. Yazdani, X. Qu, F. Ou +6 more
20210 citations
Semantic Scholar
Abstract 4123: ORIC-101 overcomes glucocorticoid receptor-mediated chemoresistance in pancreatic cancer models
Jessica D. Sun, Hai-Ying Zhou, Wayne Kong, Natalie Yuen +9 more
2020Experimental and Molecular Therapeutics0 citations
Semantic Scholar

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