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Shashikant Srivastava · SciRah

Researcher profile · Semantic Scholar

Shashikant Srivastava

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Shashikant Srivastava — researcher profile on SciRah

h-index: 35
Works: 149
Citations: 4,005

Most-cited papers

Systematic Review and Meta-analyses of the Effect of Chemotherapy on Pulmonary Mycobacterium abscessus Outcomes and Disease Recurrence
J. Pasipanodya, D. Ogbonna, B. Ferro, G. Magombedze +3 more
2017Antimicrobial Agents and Chemotherapy151 citations Open access
Semantic Scholar
Drug‐Penetration Gradients Associated with Acquired Drug Resistance in Patients with Tuberculosis
K. Dheda, L. Lenders, G. Magombedze, Shashikant Srivastava +15 more
2018American Journal of Respiratory and Critical Care Medicine134 citations Open access
Semantic Scholar
Drug Concentration Thresholds Predictive of Therapy Failure and Death in Children With Tuberculosis: Bread Crumb Trails in Random Forests
S. Swaminathan, J. Pasipanodya, G. Ramachandran, A. Hemanth Kumar +4 more
2016Clinical Infectious Diseases119 citations Open access
Semantic Scholar
Dynamic imaging in patients with tuberculosis reveals heterogeneous drug exposures in pulmonary lesions
A. Ordonez, Hechuan Wang, G. Magombedze, Camilo A. Ruiz-Bedoya +17 more
2020Nature Medicine114 citations Open access
Semantic Scholar
Linezolid Dose That Maximizes Sterilizing Effect While Minimizing Toxicity and Resistance Emergence for Tuberculosis
Shashikant Srivastava, G. Magombedze, T. Koeuth, C. Sherman +5 more
2017Antimicrobial Agents and Chemotherapy106 citations Open access
Semantic Scholar
Levofloxacin Pharmacokinetics/Pharmacodynamics, Dosing, Susceptibility Breakpoints, and Artificial Intelligence in the Treatment of Multidrug-resistant Tuberculosis.
D. Deshpande, J. Pasipanodya, S. Mpagama, Paula Bendet +8 more
2018Clinical Infectious Diseases89 citations Open access
Semantic Scholar
Meta-analyses and the evidence base for microbial outcomes in the treatment of pulmonary Mycobacterium avium–intracellulare complex disease
J. Pasipanodya, D. Ogbonna, D. Deshpande, Shashikant Srivastava +1 more
2017Journal of Antimicrobial Chemotherapy80 citations Open access
Semantic Scholar
Tigecycline Is Highly Efficacious against Mycobacterium abscessus Pulmonary Disease
B. Ferro, Shashikant Srivastava, D. Deshpande, J. Pasipanodya +4 more
2016Antimicrobial Agents and Chemotherapy70 citations Open access
Semantic Scholar
Ceftazidime-avibactam has potent sterilizing activity against highly drug-resistant tuberculosis
D. Deshpande, Shashikant Srivastava, M. Chapagain, G. Magombedze +6 more
2017Science Advances68 citations Open access
Semantic Scholar
Linezolid-based Regimens for Multidrug-resistant Tuberculosis (TB): A Systematic Review to Establish or Revise the Current Recommended Dose for TB Treatment.
M. Bolhuis, O. Akkerman, M. Sturkenboom, S. Ghimire +3 more
2018Clinical Infectious Diseases54 citations Open access
Semantic Scholar
A Faropenem, Linezolid, and Moxifloxacin Regimen for Both Drug-Susceptible and Multidrug-Resistant Tuberculosis in Children: FLAME Path on the Milky Way
D. Deshpande, Shashikant Srivastava, E. Nuermberger, J. Pasipanodya +2 more
2016Clinical Infectious Diseases45 citations Open access
Semantic Scholar
Repurposing drugs for treatment of Mycobacterium abscessus: a view to a kill.
T. Gumbo, Kayle N Cirrincione, Shashikant Srivastava
2020Journal of Antimicrobial Chemotherapy44 citations
Semantic Scholar
Concentration-Dependent Synergy and Antagonism of Linezolid and Moxifloxacin in the Treatment of Childhood Tuberculosis: The Dynamic Duo
D. Deshpande, Shashikant Srivastava, E. Nuermberger, J. Pasipanodya +2 more
2016Clinical Infectious Diseases40 citations Open access
Semantic Scholar
The discovery of ceftazidime/avibactam as an anti-Mycobacterium avium agent
D. Deshpande, Shashikant Srivastava, M. Chapagain, Pooi S. Lee +3 more
2017Journal of Antimicrobial Chemotherapy38 citations Open access
Semantic Scholar
Tedizolid is highly bactericidal in the treatment of pulmonary Mycobacterium avium complex disease
D. Deshpande, Shashikant Srivastava, J. Pasipanodya, Pooi S. Lee +1 more
2017Journal of Antimicrobial Chemotherapy37 citations Open access
Semantic Scholar
Therapeutic Drug Monitoring in Non-Tuberculosis Mycobacteria Infections
J. Alffenaar, A. Märtson, S. Heysell, Jin-Gun Cho +11 more
2021Clinical Pharmacokinetics36 citations Open access
Semantic Scholar
Ethionamide Pharmacokinetics/Pharmacodynamics-derived Dose, the Role of MICs in Clinical Outcome, and the Resistance Arrow of Time in Multidrug-resistant Tuberculosis.
D. Deshpande, J. Pasipanodya, S. Mpagama, Shashikant Srivastava +5 more
2018Clinical Infectious Diseases36 citations Open access
Semantic Scholar
Amikacin Optimal Exposure Targets in the Hollow-Fiber System Model of Tuberculosis
Shashikant Srivastava, Chawanga Modongo, C. W. Siyambalapitiyage Dona, J. Pasipanodya +2 more
2016Antimicrobial Agents and Chemotherapy35 citations Open access
Semantic Scholar
Thioridazine as Chemotherapy for Mycobacterium avium Complex Diseases
D. Deshpande, Shashikant Srivastava, Sandirai Musuka, T. Gumbo
2016Antimicrobial Agents and Chemotherapy34 citations Open access
Semantic Scholar
Antibacterial and Sterilizing Effect of Benzylpenicillin in Tuberculosis
D. Deshpande, Shashikant Srivastava, Paula Bendet, K. Martin +5 more
2017Antimicrobial Agents and Chemotherapy33 citations Open access
Semantic Scholar
Sterilizing Effect of Ertapenem-Clavulanate in a Hollow-Fiber Model of Tuberculosis and Implications on Clinical Dosing
S. P. van Rijn, Shashikant Srivastava, M. Wessels, D. van Soolingen +2 more
2017Antimicrobial Agents and Chemotherapy33 citations Open access
Semantic Scholar
Transformation Morphisms and Time-to-Extinction Analysis That Map Therapy Duration From Preclinical Models to Patients With Tuberculosis: Translating From Apples to Oranges.
G. Magombedze, J. Pasipanodya, Shashikant Srivastava, D. Deshpande +4 more
2018Clinical Infectious Diseases32 citations Open access
Semantic Scholar
Linezolid as treatment for pulmonary Mycobacterium avium disease
D. Deshpande, Shashikant Srivastava, J. Pasipanodya, T. Gumbo
2017Journal of Antimicrobial Chemotherapy32 citations Open access
Semantic Scholar
Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies
J. Alffenaar, J. D. de Steenwinkel, A. Diacon, Ulrika S. H. Simonsson +2 more
2022Frontiers in Pharmacology31 citations Open access
Semantic Scholar
Spatial Network Mapping of Pulmonary Multidrug-Resistant Tuberculosis Cavities Using RNA Sequencing
K. Dheda, L. Lenders, Shashikant Srivastava, G. Magombedze +17 more
2019American Journal of Respiratory and Critical Care Medicine30 citations Open access
Semantic Scholar
A Human Lung Challenge Model to Evaluate the Safety and Immunogenicity of PPD and Live BCG.
M. Davids, A. Pooran, Clemens Hermann, L. Mottay +14 more
2019American Journal of Respiratory and Critical Care Medicine30 citations Open access
Semantic Scholar
A novel ceftazidime/avibactam, rifabutin, tedizolid and moxifloxacin (CARTM) regimen for pulmonary Mycobacterium avium disease
D. Deshpande, Shashikant Srivastava, J. Pasipanodya, Pooi S. Lee +1 more
2017Journal of Antimicrobial Chemotherapy30 citations Open access
Semantic Scholar
The Sterilizing Effect of Intermittent Tedizolid for Pulmonary Tuberculosis.
Shashikant Srivastava, D. Deshpande, E. Nuermberger, Pooi S. Lee +3 more
2018Clinical Infectious Diseases29 citations Open access
Semantic Scholar
Challenges and a potential solution to perform drug susceptibility testing of omadacycline against nontuberculous mycobacteria
P. Shankar, Sanjay Singh, G. Boorgula, T. Gumbo +2 more
2022Tuberculosis24 citations Open access
Semantic Scholar
Susceptibility Testing of Antibiotics That Degrade Faster than the Doubling Time of Slow-Growing Mycobacteria: Ertapenem Sterilizing Effect versus Mycobacterium tuberculosis
Shashikant Srivastava, S. P. van Rijn, A. Wessels, J. Alffenaar +1 more
2016Antimicrobial Agents and Chemotherapy24 citations Open access
Semantic Scholar
Gatifloxacin Pharmacokinetics/Pharmacodynamics-based Optimal Dosing for Pulmonary and Meningeal Multidrug-resistant Tuberculosis.
D. Deshpande, J. Pasipanodya, Shashikant Srivastava, Paula Bendet +9 more
2018Clinical Infectious Diseases23 citations Open access
Semantic Scholar
Multiparameter Responses to Tedizolid Monotherapy and Moxifloxacin Combination Therapy Models of Children With Intracellular Tuberculosis.
D. Deshpande, Shashikant Srivastava, E. Nuermberger, T. Koeuth +4 more
2018Clinical Infectious Diseases22 citations Open access
Semantic Scholar
Minocycline Immunomodulates via Sonic Hedgehog Signaling and Apoptosis and Has Direct Potency Against Drug-Resistant Tuberculosis
D. Deshpande, J. Pasipanodya, Shashikant Srivastava, K. Martin +7 more
2018Journal of Infectious Diseases21 citations Open access
Semantic Scholar
Efficacy Versus Hepatotoxicity of High-dose Rifampin, Pyrazinamide, and Moxifloxacin to Shorten Tuberculosis Therapy Duration: There Is Still Fight in the Old Warriors Yet!
Shashikant Srivastava, D. Deshpande, G. Magombedze, T. Gumbo
2018Clinical Infectious Diseases21 citations Open access
Semantic Scholar
Omadacycline pharmacokinetics/pharmacodynamics in the hollow fiber model and clinical validation of efficacy to treat pulmonary Mycobacterium abscessus Disease
Sanjay Singh, Jann-Yuan Wang, S. Heysell, P. McShane +8 more
2023International Journal of Antimicrobial Agents20 citations Open access
Semantic Scholar
Cumulative Fraction of Response for Once- and Twice-Daily Delamanid in Patients with Pulmonary Multidrug-Resistant Tuberculosis
S. Mallikaarjun, M. Chapagain, Tomohiro Sasaki, N. Hariguchi +11 more
2020Antimicrobial Agents and Chemotherapy19 citations Open access
Semantic Scholar
Duration of pretomanid/moxifloxacin/pyrazinamide therapy compared with standard therapy based on time-to-extinction mathematics
Shashikant Srivastava, D. Deshpande, G. Magombedze, J. V. van Zyl +8 more
2019Journal of Antimicrobial Chemotherapy19 citations Open access
Semantic Scholar
Once-a-week tigecycline for the treatment of drug-resistant TB.
D. Deshpande, G. Magombedze, Shashikant Srivastava, Paula Bendet +5 more
2019Journal of Antimicrobial Chemotherapy18 citations Open access
Semantic Scholar
Isoniazid clearance is impaired among human immunodeficiency virus/tuberculosis patients with high levels of immune activation
C. Vinnard, S. Ravimohan, N. Tamuhla, Vijay D. Ivaturi +7 more
2017British Journal of Clinical Pharmacology17 citations Open access
Semantic Scholar
Pyrazinamide clearance is impaired among HIV/tuberculosis patients with high levels of systemic immune activation
C. Vinnard, S. Ravimohan, N. Tamuhla, J. Pasipanodya +6 more
2017PLoS ONE17 citations Open access
Semantic Scholar
A ‘shock and awe’ thioridazine and moxifloxacin combination-based regimen for pulmonary Mycobacterium avium–intracellulare complex disease
Shashikant Srivastava, D. Deshpande, C. Sherman, T. Gumbo
2017Journal of Antimicrobial Chemotherapy17 citations Open access
Semantic Scholar
Urine colorimetry for therapeutic drug monitoring of pyrazinamide during tuberculosis treatment.
Isaac J. Zentner, C. Modongo, N. Zetola, J. Pasipanodya +7 more
2017International Journal of Infectious Diseases16 citations Open access
Semantic Scholar
Clofazimine for the Treatment of Mycobacterium kansasii
Shashikant Srivastava, T. Gumbo
2018Antimicrobial Agents and Chemotherapy15 citations Open access
Semantic Scholar
Effect of specimen processing, growth supplement, and different metabolic population on Mycobacterium tuberculosis laboratory diagnosis
Shashikant Srivastava, M. Chapagain, T. Gumbo
2020PLoS ONE14 citations Open access
Semantic Scholar
Failure of the azithromycin and ethambutol combination regimen in the hollow-fibre system model of pulmonary Mycobacterium avium infection is due to acquired resistance
Shashikant Srivastava, D. Deshpande, T. Gumbo
2017Journal of Antimicrobial Chemotherapy14 citations Open access
Semantic Scholar
A programme to create short-course chemotherapy for pulmonary Mycobacterium avium disease based on pharmacokinetics/pharmacodynamics and mathematical forecasting
D. Deshpande, Shashikant Srivastava, T. Gumbo
2017Journal of Antimicrobial Chemotherapy14 citations Open access
Semantic Scholar
A Combination Regimen Design Program Based on Pharmacodynamic Target Setting for Childhood Tuberculosis: Design Rules for the Playground
Shashikant Srivastava, D. Deshpande, J. Pasipanodya, T. Thomas +3 more
2016Clinical Infectious Diseases14 citations Open access
Semantic Scholar
Cefdinir and β-Lactamase Inhibitor Independent Efficacy Against Mycobacterium tuberculosis
Shashikant Srivastava, T. Thomas, D. Howe, L. Malinga +3 more
2021Frontiers in Pharmacology13 citations Open access
Semantic Scholar
Comparison of Rifamycins for Efficacy Against Mycobacterium avium Complex and Resistance Emergence in the Hollow Fiber Model System
G. Boorgula, L. U. Jakkula, T. Gumbo, Bockgie Jung +1 more
2021Frontiers in Pharmacology13 citations Open access
Semantic Scholar
Ceftriaxone Efficacy for Mycobacterium avium Complex Lung Disease in the Hollow Fiber and Translation to Sustained Sputum Culture Conversion in Patients
D. Deshpande, G. Magombedze, G. Boorgula, M. Chapagain +2 more
2023Journal of Infectious Diseases11 citations Open access
Semantic Scholar

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T. Gumbo×48
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T. Gumbo — researcher profile on SciRah
D. Deshpande×31
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D. Deshpande — researcher profile on SciRah
J. Pasipanodya×25
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J. Pasipanodya — researcher profile on SciRah
G. Magombedze×11
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Pooi S. Lee — researcher profile on SciRah

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K. Dheda — researcher profile on SciRah

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Kayle N Cirrincione×8

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Kayle N Cirrincione — researcher profile on SciRah

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E. Nuermberger — researcher profile on SciRah

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