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Isaac J. Zentner · SciRah

Researcher profile · Semantic Scholar

Isaac J. Zentner

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Isaac J. Zentner — researcher profile on SciRah

h-index: 16
Works: 26
Citations: 750

Most-cited papers

Inhibition of homologous recombination in human cells by targeting RAD51 recombinase.
F. Huang, O. Mazina, Isaac J. Zentner, S. Cocklin +1 more
2012Journal of Medicinal Chemistry127 citations Open access
Semantic Scholar
Chimeric antigen receptor macrophages (CAR-M) sensitize HER2+ solid tumors to PD1 blockade in pre-clinical models
S. Pierini, R. Gabbasov, Maria Cecília Oliveira-Nunes, Rehman Qureshi +27 more
2025Nature Communications124 citations Open access
Semantic Scholar
Inhibiting Early-Stage Events in HIV-1 Replication by Small-Molecule Targeting of the HIV-1 Capsid
S. Kortagere, Navid Madani, Marie K. Mankowski, A. Schön +17 more
2012Journal of Virology65 citations Open access
Semantic Scholar
IgG Binding Characteristics of Rhesus Macaque FcγR
Y. Chan, Austin W. Boesch, N. Osei-Owusu, Ali Emileh +12 more
2016Journal of Immunology49 citations Open access
Semantic Scholar
Structural determinants for affinity enhancement of a dual antagonist peptide entry inhibitor of human immunodeficiency virus type-1.
H. Gopi, M. Umashankara, V. Pirrone, J. Lalonde +14 more
2008Journal of Medicinal Chemistry42 citations Open access
Semantic Scholar
Identification of a Small-Molecule Inhibitor of HIV-1 Assembly that Targets the Phosphatidylinositol (4,5)-bisphosphate Binding Site of the HIV-1 Matrix Protein
Isaac J. Zentner, Luz-Jeannette Sierra, A. Fraser, L. Maciunas +6 more
2013ChemMedChem38 citations Open access
Semantic Scholar
Introducing metallocene into a triazole peptide conjugate reduces its off-rate and enhances its affinity and antiviral potency for HIV-1 gp120
H. Gopi, S. Cocklin, V. Pirrone, Karyn McFadden +7 more
2009Journal of Molecular Recognition38 citations Open access
Semantic Scholar
A carrier protein strategy yields the structure of dalbavancin
N. J. Economou, V. Nahoum, S. Weeks, Kimberly C. Grasty +5 more
2012Journal of the American Chemical Society37 citations Open access
Semantic Scholar
Active Core in a Triazole Peptide Dual Site Antagonist of HIV-1 gp120
M. Umashankara, Karyn McFadden, Isaac J. Zentner, A. Schön +7 more
2010ChemMedChem35 citations Open access
Semantic Scholar
126An Optimized, Synthetic DNA Vaccine Encoding the Toxin A and Toxin B Receptor Binding Domains of Clostridium difficile Induces Protective Antibody Responses In Vivo
Scott M. Baliban, Amanda Michael, Berje H. Shammassian, Shikata Mudakha +12 more
2014Infection and Immunity33 citations Open access
Semantic Scholar
Structure of the complex between teicoplanin and a bacterial cell-wall peptide: use of a carrier-protein approach.
N. J. Economou, Isaac J. Zentner, E. Lazo, J. Jakoncic +5 more
2013Acta Crystallographica Section D: Biological Crystallography25 citations Open access
Semantic Scholar
Discovery of a small-molecule antiviral targeting the HIV-1 matrix protein
Isaac J. Zentner, Luz-Jeannette Sierra, L. Maciunas, A. Vinnik +5 more
2012Bioorganic & Medicinal Chemistry Letters25 citations Open access
Semantic Scholar
Urine colorimetry to detect Low rifampin exposure during tuberculosis therapy: a proof-of-concept study
Isaac J. Zentner, H. Schlecht, Lorna Khensouvann, N. Tamuhla +7 more
2016BMC Infectious Diseases22 citations Open access
Semantic Scholar
Determination of Rifampin Concentrations by Urine Colorimetry and Mobile Phone Readout for Personalized Dosing in Tuberculosis Treatment.
Claire Szipszky, Daniel Van Aartsen, S. Criddle, P. Rao +9 more
2020Journal of the Pediatric Infectious Diseases Society19 citations Open access
Semantic Scholar
HIV-1 Env gp120 Structural Determinants for Peptide Triazole Dual Receptor Site Antagonism
Ferit Tuzer, Navid Madani, Kantharaju Kamanna, Isaac J. Zentner +8 more
2012Proteins: Structure, Function, and Bioinformatics17 citations Open access
Semantic Scholar
Urine colorimetry for therapeutic drug monitoring of pyrazinamide during tuberculosis treatment.
Isaac J. Zentner, C. Modongo, N. Zetola, J. Pasipanodya +7 more
2017International Journal of Infectious Diseases16 citations Open access
Semantic Scholar
Attainment of target rifampicin concentrations in cerebrospinal fluid during treatment of tuberculous meningitis
A. Mezochow, K. Thakur, Isaac J. Zentner, S. Subbian +2 more
2019International Journal of Infectious Diseases14 citations Open access
Semantic Scholar
Redox Imbalance and Oxidative DNA Damage During Isoniazid Treatment of HIV-Associated Tuberculosis: A Clinical and Translational Pharmacokinetic Study
Isaac J. Zentner, Hyun-moon Back, L. Kagan, S. Subbian +6 more
2020Frontiers in Pharmacology11 citations Open access
Semantic Scholar
Conformational and Structural Features of HIV-1 gp120 Underlying Dual Receptor Antagonism by the Cross-Reactive Neutralizing Antibody, m18
S. Gift, Isaac J. Zentner, A. Schön, Karyn McFadden +12 more
2011Biochemistry6 citations Open access
Semantic Scholar
Author Correction: Chimeric antigen receptor macrophages (CAR-M) sensitize HER2+ solid tumors to PD1 blockade in pre-clinical models
S. Pierini, R. Gabbasov, Maria Cecília Oliveira-Nunes, Rehman Qureshi +27 more
2025Nature Communications5 citations Open access
Semantic Scholar
Redox imbalance and oxidative DNA damage during isoniazid treatment: A clinical and translational pharmacokinetic study
Isaac J. Zentner, Hyun-moon Back, L. Kagan, S. Subbian +6 more
20202 citations Open access
Semantic Scholar
A Pilot Study of Immune Activation and Rifampin Absorption in HIV-Infected Patients without Tuberculosis Infection: A Short Report
C. Vinnard, Isabel Manley, Brittney Scott, Mariana Bernui +4 more
2017Tuberculosis Research and Treatment2 citations Open access
Semantic Scholar
Abasic Phosphorothioate Oligomers Inhibit HIV-1 Reverse Transcription and Block Virus Transmission across Polarized Ectocervical Organ Cultures
J. Fraietta, Yvonne M. Mueller, Karissa Lozenski, D. Ratner +15 more
2014Antimicrobial Agents and Chemotherapy1 citations Open access
Semantic Scholar
Monoclonal Antibody m18 Paratope Leading to Dual Receptor Antagonism of HIV-1 gp120
S. Gift, Karyn McFadden, Isaac J. Zentner, S. Rajagopal +3 more
2011Biochemistry0 citations Open access
Semantic Scholar
The monoclonal antibody M18 suppresses HIV-1 gp120 receptor interactions and envelope spike function
Syna A. Kuriakose, Isaac J. Zentner, A. Schön, Karyn McFadden +6 more
20100 citations
Semantic Scholar
Rab6A is Required for the Post-Entry Nuclear Localization of HIV-1
Isaac J. Zentner
0 citations Open access
Semantic Scholar

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