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E. Wahle · SciRah

Researcher profile · Semantic Scholar

E. Wahle

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E. Wahle — researcher profile on SciRah

h-index: 53
Works: 118
Citations: 9,926

Most-cited papers

Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures
E. van Dijk, N. Cougot, Sylke Meyer, S. Babajko +2 more
2002EMBO Journal502 citations Open access
Semantic Scholar
Messenger RNA Turnover in Eukaryotes: Pathways and Enzymes
Sylke Meyer, C. Temme, E. Wahle
2004Critical reviews in biochemistry and molecular biology384 citations
Semantic Scholar
Structure and function of poly(A) binding proteins.
Uwe Kühn, E. Wahle
2004Biochimica et Biophysica Acta349 citations
Semantic Scholar
3'-End processing of pre-mRNA in eukaryotes.
E. Wahle, Ursula Rüegsegger
1999FEMS Microbiology Reviews325 citations Open access
Semantic Scholar
Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs.
D. Weidensdorfer, Nadine Stöhr, Anne Baude, M. Lederer +5 more
2008RNA: A publication of the RNA Society322 citations Open access
Semantic Scholar
Control of poly(A) tail length
Christian R. Eckmann, Christiane Rammelt, E. Wahle
2011Wiley Interdisciplinary Reviews - RNA281 citations
Semantic Scholar
The deadenylating nuclease (DAN) is involved in poly(A) tail removal during the meiotic maturation of Xenopus oocytes
Christof G. Körner, Michael Wormington, M. Muckenthaler, S. Schneider +2 more
1998EMBO Journal257 citations Open access
Semantic Scholar
Poly(A) Tail Shortening by a Mammalian Poly(A)-specific 3′-Exoribonuclease*
Christof G. Körner, E. Wahle
1997Journal of Biological Chemistry251 citations Open access
Semantic Scholar
RNA decay machines: deadenylation by the Ccr4-not and Pan2-Pan3 complexes.
E. Wahle, G. Winkler
2013Biochimica et Biophysica Acta250 citations
Semantic Scholar
Nuclear inclusions in oculopharyngeal muscular dystrophy consist of poly(A) binding protein 2 aggregates which sequester poly(A) RNA.
Â. Calado, F. Tomé, B. Brais, G. Rouleau +3 more
2000Human Molecular Genetics242 citations
Semantic Scholar
Poly(A) tail metabolism and function in eucaryotes.
A. Sachs, E. Wahle
1993Journal of Biological Chemistry222 citations Open access
Semantic Scholar
A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in Drosophila
C. Temme, Sophie Zaessinger, Sylke Meyer, M. Simonelig +1 more
2004EMBO Journal221 citations Open access
Semantic Scholar
Reconstitution of CPSF active in polyadenylation: recognition of the polyadenylation signal by WDR33
L. Schönemann, Uwe Kühn, G. Martin, P. Schäfer +4 more
2014Genes & Development208 citations Open access
Semantic Scholar
Poly(A) Tail Length Is Controlled by the Nuclear Poly(A)-binding Protein Regulating the Interaction between Poly(A) Polymerase and the Cleavage and Polyadenylation Specificity Factor*
Uwe Kühn, Miriam Gündel, Anne Knoth, Yvonne Kerwitz +2 more
2009Journal of Biological Chemistry206 citations Open access
Semantic Scholar
Poly(A) Tail Length Control Is Caused by Termination of Processive Synthesis (*)
E. Wahle
1995Journal of Biological Chemistry206 citations Open access
Semantic Scholar
Cap‐dependent deadenylation of mRNA
E. Dehlin, Michael Wormington, Christof G. Körner, E. Wahle
2000EMBO Journal192 citations Open access
Semantic Scholar
The biochemistry of polyadenylation.
E. Wahle, Walter Keller
1996TIBS -Trends in Biochemical Sciences. Regular ed180 citations
Semantic Scholar
Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation.
C. Temme, Lian-Bing Zhang, E. Kremmer, C. Ihling +4 more
2010RNA: A publication of the RNA Society176 citations Open access
Semantic Scholar
Stimulation of poly(A) polymerase through a direct interaction with the nuclear poly(A) binding protein allosterically regulated by RNA
Yvonne Kerwitz, Uwe Kühn, H. Lilie, Anne Knoth +4 more
2003EMBO Journal167 citations Open access
Semantic Scholar
Maturation of mammalian H/ACA box snoRNAs: PAPD5-dependent adenylation and PARN-dependent trimming.
Heike Berndt, Christiane Harnisch, Christiane Rammelt, Nadine Stöhr +6 more
2012RNA: A publication of the RNA Society157 citations Open access
Semantic Scholar
Unusual Sites of Arginine Methylation in Poly(A)-binding Protein II and in Vitro Methylation by Protein Arginine Methyltransferases PRMT1 and PRMT3*
Jason J. Smith, Karl Peter Rücknagel, A. Schierhorn, Jie Tang +4 more
1999Journal of Biological Chemistry151 citations Open access
Semantic Scholar
Immunodetection of poly(A) binding protein II in the cell nucleus.
S. Krause, S. Fakan, K. Weis, E. Wahle
1994Experimental Cell Research133 citations Open access
Semantic Scholar
3'-end cleavage and polyadenylation of mRNA precursors.
E. Wahle
1995Biochimica et Biophysica Acta132 citations
Semantic Scholar
Deciphering the mRNP Code: RNA-Bound Determinants of Post-Transcriptional Gene Regulation.
N. Gehring, E. Wahle, U. Fischer
2017TIBS -Trends in Biochemical Sciences. Regular ed123 citations
Semantic Scholar
The intranuclear mobility of messenger RNA binding proteins is ATP dependent and temperature sensitive
Alexandre Calapez, Henrique M. Pereira, Â. Calado, José Braga +6 more
2002Journal of Cell Biology123 citations Open access
Semantic Scholar
Nuclear polyadenylation factors recognize cytoplasmic polyadenylation elements.
Andrea Bilger, C. Fox, E. Wahle, M. Wickens
1994Genes & Development122 citations Open access
Semantic Scholar
Structural insight into poly(A) binding and catalytic mechanism of human PARN
Mou-Sheng Wu, Michael Reuter, H. Lilie, Yu-Ying Liu +2 more
2005EMBO Journal119 citations Open access
Semantic Scholar
Asymmetric Arginine Dimethylation of Heterogeneous Nuclear Ribonucleoprotein K by Protein-arginine Methyltransferase 1 Inhibits Its Interaction with c-Src*
A. Ostareck-Lederer, D. Ostareck, K. P. Rucknagel, A. Schierhorn +5 more
2006Journal of Biological Chemistry112 citations Open access
Semantic Scholar
An essential cytoplasmic function for the nuclear poly(A) binding protein, PABP2, in poly(A) tail length control and early development in Drosophila.
Béatrice Benoit, Géraldine Mitou, A. Chartier, C. Temme +4 more
2005Developmental Cell110 citations Open access
Semantic Scholar
Deciphering the cellular pathway for transport of poly(A)-binding protein II.
Â. Calado, U. Kutay, Uwe Kühn, E. Wahle +1 more
2000RNA: A publication of the RNA Society104 citations Open access
Semantic Scholar
The mechanism of 3' cleavage and polyadenylation of eukaryotic pre-mRNA.
E. Wahle, Uwe Kühn
1997Progress in Nucleic Acid Research and Molecular Biology97 citations
Semantic Scholar
Deadenylation of mRNA by the CCR4–NOT complex in Drosophila: molecular and developmental aspects
C. Temme, M. Simonelig, E. Wahle
2014Frontiers in Genetics92 citations Open access
Semantic Scholar
The nuclear poly(A) binding protein, PABP2, forms an oligomeric particle covering the length of the poly(A) tail.
Rebecca A. Keller, Uwe Kühn, Mateo Aragon, Larissa Bornikova +2 more
2000Journal of Molecular Biology91 citations
Semantic Scholar
Mammalian poly(A)-binding protein II. Physical properties and binding to polynucleotides.
E. Wahle, A. Lustig, P. Jenö, P. Maurer
1993Journal of Biological Chemistry91 citations Open access
Semantic Scholar
Isolation of genomic and cDNA clones encoding bovine poly(A) binding protein II.
A. Nemeth, S. Krause, Diana Blank, Andreas Jenny +3 more
1995Nucleic Acids Research88 citations Open access
Semantic Scholar
Control of poly(A) polymerase level is essential to cytoplasmic polyadenylation and early development in Drosophila
François Juge, Sophie Zaessinger, C. Temme, E. Wahle +1 more
2002EMBO Journal83 citations Open access
Semantic Scholar
Smaug assembles an ATP‐dependent stable complex repressing nanos mRNA translation at multiple levels
M. Jeske, B. Moritz, Alexander Anders, E. Wahle
2011EMBO Journal82 citations Open access
Semantic Scholar
The RNA Binding Domains of the Nuclear poly(A)-binding Protein* 210
Uwe Kühn, A. Nemeth, Sylke Meyer, E. Wahle
2003Journal of Biological Chemistry80 citations Open access
Semantic Scholar
Translational repression of the Drosophila nanos mRNA involves the RNA helicase Belle and RNA coating by Me31B and Trailer hitch
Michael Götze, Jérémy Dufourt, C. Ihling, Christiane Rammelt +6 more
2017bioRxiv62 citations Open access
Semantic Scholar
Rapid ATP-dependent Deadenylation of nanos mRNA in a Cell-free System from Drosophila Embryos*
M. Jeske, Sylke Meyer, C. Temme, D. Freudenreich +1 more
2006Journal of Biological Chemistry55 citations Open access
Semantic Scholar
Trinucleotide expansions leading to an extended poly‐l‐alanine segment in the poly (A) binding protein PABPN1 cause fibril formation
T. Scheuermann, B. Schulz, A. Blume, E. Wahle +2 more
2003Protein Science55 citations Open access
Semantic Scholar
Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition
Wen-Xi Cao, Sarah Kabelitz, Meera Gupta, E. Yeung +12 more
2019bioRxiv53 citations Open access
Semantic Scholar
The Drosophila poly(A)-binding protein II is ubiquitous throughout Drosophila development and has the same function in mRNA polyadenylation as its bovine homolog in vitro.
Béatrice Benoit, A. Nemeth, Nathalie Aulner, Uwe Kühn +3 more
1999Nucleic Acids Research53 citations Open access
Semantic Scholar
Degradation of hsp70 and Other mRNAs in Drosophila via the 5′–3′ Pathway and Its Regulation by Heat Shock*
Clemens Bönisch, C. Temme, B. Moritz, E. Wahle
2007Journal of Biological Chemistry48 citations Open access
Semantic Scholar
Type I Arginine Methyltransferases PRMT1 and PRMT-3 Act Distributively*
Knut Kölbel, C. Ihling, K. Bellmann-Sickert, I. Neundorf +4 more
2009Journal of Biological Chemistry47 citations Open access
Semantic Scholar
Reconstitution of mammalian cleavage factor II involved in 3′ processing of mRNA precursors
P. Schäfer, Christian Tüting, L. Schönemann, Uwe Kühn +8 more
2018bioRxiv46 citations Open access
Semantic Scholar
Promiscuous Modification of the Nuclear Poly(A)-binding Protein by Multiple Protein-arginine Methyltransferases Does Not Affect the Aggregation Behavior*
Katharina Fronz, Silke Otto, Knut Kölbel, Uwe Kühn +5 more
2008Journal of Biological Chemistry46 citations Open access
Semantic Scholar
Reconstitution of 3′ end processing of mammalian pre-mRNA reveals a central role of RBBP6
M. Schmidt, F. Kluge, Felix Sandmeir, Uwe Kühn +5 more
2022Genes & Development43 citations Open access
Semantic Scholar
Arginine Methylation of the Nuclear Poly(A) Binding Protein Weakens the Interaction with Its Nuclear Import Receptor, Transportin*
Katharina Fronz, Stefan Güttinger, Kerstin Burkert, Uwe Kühn +3 more
2011Journal of Biological Chemistry41 citations Open access
Semantic Scholar
Crystal structure of the EndoG/EndoGI complex: mechanism of EndoG inhibition
B. Loll, Maike Gebhardt, E. Wahle, A. Meinhart
2009Nucleic Acids Research38 citations Open access
Semantic Scholar

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Uwe Kühn×15
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Uwe Kühn — researcher profile on SciRah
C. Temme×9
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C. Temme — researcher profile on SciRah
M. Simonelig×7
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M. Simonelig — researcher profile on SciRah
C. Ihling×6
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Sylke Meyer — researcher profile on SciRah

A. Schierhorn×5

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Christiane Rammelt×4

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Christiane Rammelt — researcher profile on SciRah

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A. Sinz — researcher profile on SciRah

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A. Nemeth — researcher profile on SciRah

Nadine Stöhr×3

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Christof G. Körner×3

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Christof G. Körner — researcher profile on SciRah