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G. Bokoch · SciRah

Researcher profile · Semantic Scholar

G. Bokoch

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G. Bokoch — researcher profile on SciRah

h-index: 106
Works: 272
Citations: 38K

Most-cited papers

Biology of the p21-activated kinases.
G. Bokoch
2003Annual Review of Biochemistry1,156 citations
Semantic Scholar
GDIs: central regulatory molecules in Rho GTPase activation.
C. Dermardirossian, G. Bokoch
2005Trends in Cell Biology677 citations
Semantic Scholar
NADPH oxidases: not just for leukocytes anymore!
G. Bokoch, U. Knaus
2003TIBS -Trends in Biochemical Sciences. Regular ed402 citations
Semantic Scholar
GEF-H1 couples nocodazole-induced microtubule disassembly to cell contractility via RhoA.
Yuan-Chen Chang, Perihan Nalbant, Jörg Birkenfeld, Z. Chang +1 more
2008Molecular Biology of the Cell366 citations Open access
Semantic Scholar
Cofilin phosphatases and regulation of actin dynamics.
Timothy Y. Huang, C. Dermardirossian, G. Bokoch
2006Current Opinion in Cell Biology363 citations
Semantic Scholar
Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics
A. Gohla, Jörg Birkenfeld, G. Bokoch
2005Nature Cell Biology338 citations
Semantic Scholar
Regulation of innate immunity by Rho GTPases.
G. Bokoch
2005Trends in Cell Biology324 citations
Semantic Scholar
Regulation of leading edge microtubule and actin dynamics downstream of Rac1
Torsten Wittmann, G. Bokoch, C. Waterman-Storer
2003Journal of Cell Biology275 citations Open access
Semantic Scholar
Phosphorylation of RhoGDI by Pak1 mediates dissociation of Rac GTPase.
C. Dermardirossian, A. Schnelzer, G. Bokoch
2004Molecules and Cells252 citations Open access
Semantic Scholar
Regulation of Microtubule Destabilizing Activity of Op18/Stathmin Downstream of Rac1*
Torsten Wittmann, G. Bokoch, C. Waterman-Storer
2004Journal of Biological Chemistry252 citations Open access
Semantic Scholar
GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases.
Jörg Birkenfeld, Perihan Nalbant, B. Bohl, O. Pertz +2 more
2007Developmental Cell246 citations Open access
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PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility
Yangmi Lim, S. Lim, Alok Tomar, M. Gardel +12 more
2008Journal of Cell Biology234 citations Open access
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Cofilin activity downstream of Pak1 regulates cell protrusion efficiency by organizing lamellipodium and lamella actin networks.
Violaine Delorme, M. Machacek, C. Dermardirossian, K. Anderson +5 more
2007Developmental Cell207 citations Open access
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A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells
D. Gianni, Nicolas Taulet, Hui Zhang, C. Dermardirossian +6 more
2010ACS Chemical Biology195 citations Open access
Semantic Scholar
Reactive oxygen species regulate a slingshot-cofilin activation pathway.
Jun-Sub Kim, Timothy Y. Huang, G. Bokoch
2009Molecular Biology of the Cell188 citations Open access
Semantic Scholar
p21-activated Kinase 1 Phosphorylates and Regulates 14-3-3 Binding to GEF-H1, a Microtubule-localized Rho Exchange Factor*
F. Zenke, M. Krendel, C. Dermardirossian, C. King +2 more
2004Journal of Biological Chemistry188 citations Open access
Semantic Scholar
Cellular functions of GEF-H1, a microtubule-regulated Rho-GEF: is altered GEF-H1 activity a crucial determinant of disease pathogenesis?
Jörg Birkenfeld, Perihan Nalbant, S. Yoon, G. Bokoch
2008Trends in Cell Biology185 citations
Semantic Scholar
Mechanism of human dermal fibroblast migration driven by type I collagen and platelet-derived growth factor-BB.
Wei Li, Jian-Hua Fan, Mei Chen, Sheng-Xi Guan +3 more
2003Molecular Biology of the Cell182 citations
Semantic Scholar
Phosphorylation of RhoGDI by Src regulates Rho GTPase binding and cytosol-membrane cycling.
C. Dermardirossian, G. Rocklin, J. Seo, G. Bokoch
2006Molecular Biology of the Cell168 citations Open access
Semantic Scholar
GEF-H1 is involved in agonist-induced human pulmonary endothelial barrier dysfunction.
A. Birukova, D. Adyshev, B. Gorshkov, G. Bokoch +2 more
2006American Journal of Physiology - Lung cellular and Molecular Physiology159 citations
Semantic Scholar
Epoxycyclopentenone-Containing Oxidized Phospholipids Restore Endothelial Barrier Function via Cdc42 and Rac
K. Birukov, V. Bochkov, A. Birukova, K. Kawkitinarong +6 more
2004Circulation Research154 citations
Semantic Scholar
Epac/Rap and PKA are novel mechanisms of ANP‐induced Rac‐mediated pulmonary endothelial barrier protection
Anna A. Birukova, T. Zagranichnaya, Elena Alekseeva, G. Bokoch +1 more
2008Journal of Cellular Physiology150 citations Open access
Semantic Scholar
Regulation of the Phagocyte NADPH Oxidase by Rac GTPase
G. Bokoch, Tiemin Zhao
2006Antioxidants and Redox Signaling149 citations
Semantic Scholar
Guanine nucleotide exchange factor-H1 regulates cell migration via localized activation of RhoA at the leading edge.
Perihan Nalbant, Yuan-Chen Chang, Jörg Birkenfeld, Z. Chang +1 more
2009Molecular Biology of the Cell147 citations Open access
Semantic Scholar
P-Rex1 is a primary Rac2 guanine nucleotide exchange factor in mouse neutrophils.
Xuemei Dong, Zhicheng Mo, G. Bokoch, Cai-Ying Guo +2 more
2005Current Biology140 citations Open access
Semantic Scholar
The involvement of the tyrosine kinase c-Src in the regulation of reactive oxygen species generation mediated by NADPH oxidase-1.
D. Gianni, B. Bohl, S. Courtneidge, G. Bokoch
2008Molecular Biology of the Cell137 citations Open access
Semantic Scholar
β-Arrestin-dependent Regulation of the Cofilin Pathway Downstream of Protease-activated Receptor-2*
M. Zoudilova, Puneet Kumar, Lan Ge, Ping Wang +2 more
2007Journal of Biological Chemistry137 citations Open access
Semantic Scholar
1 Rac 1 links leading edge and uropod events through Rho and myosin activation during chemotaxis
K. Pestonjamasp, C. Forster, Chun-Xiang Sun, E. M. Gardiner +4 more
2006116 citations
Semantic Scholar
Novel p47phox-related organizers regulate NADPH oxidase 1 (Nox1) activity and localization
D. Gianni, Begoña Díaz, Nicolas Taulet, B. Fowler +2 more
2009Science Signaling105 citations Open access
Semantic Scholar
Regulation of Nox1 Activity via Protein Kinase A-mediated Phosphorylation of NoxA1 and 14-3-3 Binding*
Jun-Sub Kim, B. Diebold, B. Babior, U. Knaus +1 more
2007Journal of Biological Chemistry103 citations Open access
Semantic Scholar
Chronophin mediates an ATP-sensing mechanism for cofilin dephosphorylation and neuronal cofilin-actin rod formation
Timothy Y. Huang, L. Minamide, J. Bamburg, G. Bokoch
2008Developmental Cell100 citations Open access
Semantic Scholar
Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration
Violaine Delorme-Walker, J. Peterson, J. Chernoff, Clare M. Waterman +3 more
2011Journal of Cell Biology94 citations Open access
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Antagonistic Cross-talk between Rac and Cdc42 GTPases Regulates Generation of Reactive Oxygen Species*
B. Diebold, B. Fowler, Justine Lu, M. Dinauer +1 more
2004Journal of Biological Chemistry94 citations Open access
Semantic Scholar
Mechanism of p21-activated Kinase 6-mediated Inhibition of Androgen Receptor Signaling*
N. Schrantz, J. da Silva Correia, B. Fowler, Q. Ge +2 more
2004Journal of Biological Chemistry93 citations Open access
Semantic Scholar
Bacillus anthracis Toxins Inhibit Human Neutrophil NADPH Oxidase Activity1
M. Crawford, C. Aylott, R. Bourdeau, G. Bokoch
2006Journal of Immunology92 citations Open access
Semantic Scholar
c-Src–Mediated Phosphorylation of NoxA1 and Tks4 Induces the Reactive Oxygen Species (ROS)–Dependent Formation of Functional Invadopodia in Human Colon Cancer Cells
D. Gianni, Nicolas Taulet, C. Dermardirossian, G. Bokoch
2010Molecular Biology of the Cell89 citations Open access
Semantic Scholar
Regulation of hypoxic neuronal death signaling by neuroglobin
A. A. Khan, Xiao Mao, Surita Banwait, Celine M. DerMardirossian +3 more
2008The FASEB Journal88 citations Open access
Semantic Scholar
The molecular basis for adhesion-mediated suppression of reactive oxygen species generation by human neutrophils.
Tiemin Zhao, Valérie Benard, B. Bohl, G. Bokoch
2003Journal of Clinical Investigation78 citations Open access
Semantic Scholar
Isolation and Characterization of Cytoplasmic Cofilin-Actin Rods*
L. Minamide, S. Maiti, Judith A. Boyle, Richard C. Davis +6 more
2009Journal of Biological Chemistry77 citations Open access
Semantic Scholar
Constitutive p21-activated kinase (PAK) activation in breast cancer cells as a result of mislocalization of PAK to focal adhesions.
M. Stofega, L. C. Sanders, E. M. Gardiner, G. Bokoch
2004Molecular Biology of the Cell76 citations Open access
Semantic Scholar
Identification of a Conserved Rac-binding Site on NADPH Oxidases Supports a Direct GTPase Regulatory Mechanism*
Y. Kao, D. Gianni, B. Bohl, Ross M. Taylor +1 more
2008Journal of Biological Chemistry73 citations Open access
Semantic Scholar
Neutrophil Methods and Protocols
M. Quinn, F. DeLeo, G. Bokoch
2007Methods in Molecular Biology™69 citations Open access
Semantic Scholar
Human neutrophils coordinate chemotaxis by differential activation of Rac1 and Rac2
Hui Zhang, Chun-Xiang Sun, M. Glogauer, G. Bokoch
2009Journal of Immunology67 citations Open access
Semantic Scholar
The Microtubule-associated Rho Activating Factor GEF-H1 interacts with Exocyst complex to regulate Vesicle Traffic
Ritu Pathak, Violaine Delorme-Walker, Michael Howell, A. Anselmo +3 more
2012Developmental Cell66 citations Open access
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Signaling requirements for translocation of P‐Rex1, a key Rac2 exchange factor involved in chemoattractant‐stimulated human neutrophil function
Tiemin Zhao, Perihan Nalbant, M. Hoshino, Xuemei Dong +2 more
2007Journal of Leukocyte Biology66 citations
Semantic Scholar
Stimulus-dependent Regulation of the Phagocyte NADPH Oxidase by a VAV1, Rac1, and PAK1 Signaling Axis*
K. Roepstorff, Izabela Rasmussen, M. Sawada, Cristophe Cudre-Maroux +4 more
2008Journal of Biological Chemistry64 citations Open access
Semantic Scholar
Emerging Evidence for the Importance of Phosphorylation in the Regulation of NADPH Oxidases
G. Bokoch, B. Diebold, Jun-Sub Kim, D. Gianni
2009Antioxidants and Redox Signaling62 citations Open access
Semantic Scholar
Faculty Opinions recommendation of A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis.
G. Bokoch
200762 citations
Semantic Scholar
Integrin-linked kinase regulates Bergmann glial differentiation during cerebellar development.
R. Belvindrah, Perihan Nalbant, Sheng-Quan Ding, Chuan-Yue Wu +2 more
2006Molecular and cellular neurosciences59 citations
Semantic Scholar
FGD2, a CDC42-specific Exchange Factor Expressed by Antigen-presenting Cells, Localizes to Early Endosomes and Active Membrane Ruffles*
C. Huber, A. Mårtensson, G. Bokoch, D. Nemazee +1 more
2008Journal of Biological Chemistry58 citations Open access
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Perihan Nalbant×7
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B. Bohl×6
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D. Gianni×6
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Jörg Birkenfeld

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Timothy Y. Huang×4

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C. Waterman-Storer×4

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Torsten Wittmann×3

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Tiemin Zhao — researcher profile on SciRah

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