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P. H. Weigel · SciRah

Researcher profile · Semantic Scholar

P. H. Weigel

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P. H. Weigel — researcher profile on SciRah

h-index: 56
Works: 198
Citations: 9,111

Most-cited papers

Hyaluronan Synthases: A Decade-plus of Novel Glycosyltransferases*
P. H. Weigel, P. DeAngelis
2007Journal of Biological Chemistry352 citations Open access
Semantic Scholar
Identification of the Hyaluronan Receptor for Endocytosis (HARE)*
Bin Zhou, Janet A. Weigel, LeAnn J. Fauss, P. H. Weigel
2000Journal of Biological Chemistry274 citations Open access
Semantic Scholar
Hyaluronic Acid Production in Bacillus subtilis
B. Widner, R. Behr, Steve Von Dollen, Maria R. Tang +6 more
2005Applied and Environmental Microbiology269 citations Open access
Semantic Scholar
Glycans as endocytosis signals: the cases of the asialoglycoprotein and hyaluronan/chondroitin sulfate receptors.
P. H. Weigel, Jasper H. N. Yik
2002Biochimica et Biophysica Acta216 citations
Semantic Scholar
Abundance and location of proteoglycans and hyaluronan within normal and myxomatous mitral valves
Vishal Gupta, J. Barzilla, Joe S. Mendez, Elizabeth H. Stephens +5 more
2008Cardiovascular pathology138 citations Open access
Semantic Scholar
Expression, Processing, and Glycosaminoglycan Binding Activity of the Recombinant Human 315-kDa Hyaluronic Acid Receptor for Endocytosis (HARE)*
E. Harris, S. Kyosseva, Janet A. Weigel, P. H. Weigel
2007Journal of Biological Chemistry132 citations Open access
Semantic Scholar
The Human Hyaluronan Receptor for Endocytosis (HARE/Stabilin-2) Is a Systemic Clearance Receptor for Heparin*
E. Harris, Janet A. Weigel, P. H. Weigel
2008Journal of Biological Chemistry122 citations Open access
Semantic Scholar
Hyaluronan Synthase: The Mechanism of Initiation at the Reducing End and a Pendulum Model for Polysaccharide Translocation to the Cell Exterior
P. H. Weigel
2015International Journal of Cell Biology120 citations Open access
Semantic Scholar
DIGESTION PRODUCTS OF THE PH20 HYALURONIDASE INHIBIT REMYELINATION
M. Preston, X. Gong, W. Su, Steven Matsumoto +11 more
2013Annals of Neurology103 citations Open access
Semantic Scholar
Purification and Lipid Dependence of the Recombinant Hyaluronan Synthases from Streptococcus pyogenes andStreptococcus equisimilis *
V. L. Tlapak-Simmons, B. Baggenstoss, T. Clyne, P. H. Weigel
1999Journal of Biological Chemistry98 citations Open access
Semantic Scholar
Topological Organization of the Hyaluronan Synthase fromStreptococcus pyogenes *
C. Heldermon, P. DeAngelis, P. H. Weigel
2001Journal of Biological Chemistry97 citations Open access
Semantic Scholar
Functional Characteristics and Catalytic Mechanisms of the Bacterial Hyaluronan Synthases
P. H. Weigel
2002IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology94 citations
Semantic Scholar
Mechanisms of cell death in primary cortical neurons and PC12 cells
U. Reimann‐Philipp, Roma Ovase, P. H. Weigel, P. Grammas
2001Journal of Neuroscience Research93 citations
Semantic Scholar
The ligand-binding profile of HARE: hyaluronan and chondroitin sulfates A, C, and D bind to overlapping sites distinct from the sites for heparin, acetylated low-density lipoprotein, dermatan sulfate, and CS-E.
E. Harris, P. H. Weigel
2008Glycobiology92 citations Open access
Semantic Scholar
The Active Streptococcal Hyaluronan Synthases (HASs) Contain a Single HAS Monomer and Multiple Cardiolipin Molecules*
V. L. Tlapak-Simmons, E. Kempner, B. Baggenstoss, P. H. Weigel
1998Journal of Biological Chemistry91 citations Open access
Semantic Scholar
Short Communication Microvessels from Alzheimer’s Disease Brains Kill Neurons in Vitro
P. Grammas, P. Moore, P. H. Weigel
199989 citations
Semantic Scholar
Endocytic Function, Glycosaminoglycan Specificity, and Antibody Sensitivity of the Recombinant Human 190-kDa Hyaluronan Receptor for Endocytosis (HARE)*
E. Harris, Janet A. Weigel, P. H. Weigel
2004Journal of Biological Chemistry84 citations Open access
Semantic Scholar
A Blocking Antibody to the Hyaluronan Receptor for Endocytosis (HARE) Inhibits Hyaluronan Clearance by Perfused Liver*
Janet A. Weigel, R. C. Raymond, C. McGary, Anil Singh +1 more
2003Journal of Biological Chemistry84 citations Open access
Semantic Scholar
Molecular cloning and functional expression of the rat 175-kDa hyaluronan receptor for endocytosis.
Bin Zhou, Janet A. Weigel, A. Saxena, P. H. Weigel
2002Molecular Biology of the Cell81 citations Open access
Semantic Scholar
Kinetic Characterization of the Recombinant Hyaluronan Synthases from Streptococcus pyogenes and Streptococcus equisimilis *
V. L. Tlapak-Simmons, B. Baggenstoss, K. Kumari, C. Heldermon +1 more
1999Journal of Biological Chemistry77 citations Open access
Semantic Scholar
The Hyaluronan Receptor for Endocytosis (HARE) Activates NF-κB-mediated Gene Expression in Response to 40–400-kDa, but Not Smaller or Larger, Hyaluronans*
Madhu S. Pandey, B. Baggenstoss, Jennifer L. Washburn, E. Harris +1 more
2013Journal of Biological Chemistry75 citations Open access
Semantic Scholar
Characterization of the purified hyaluronan synthase from Streptococcus equisimilis.
V. L. Tlapak-Simmons, Christina A Baron, P. H. Weigel
2004Biochemistry69 citations
Semantic Scholar
The Cytoplasmic Domain of the Hyaluronan Receptor for Endocytosis (HARE) Contains Multiple Endocytic Motifs Targeting Coated Pit-mediated Internalization*
Madhu S. Pandey, E. Harris, Janet A. Weigel, P. H. Weigel
2008Journal of Biological Chemistry68 citations Open access
Semantic Scholar
Purification and Subunit Characterization of the Rat Liver Endocytic Hyaluronan Receptor*
Bin Zhou, J. A. Oka, Anil Singh, P. H. Weigel
1999Journal of Biological Chemistry68 citations Open access
Semantic Scholar
Hyaluronan Biosynthesis by Class I Streptococcal Hyaluronan Synthases Occurs at the Reducing End*
V. L. Tlapak-Simmons, Christina A Baron, R. Gotschall, D. Haque +2 more
2005Journal of Biological Chemistry63 citations Open access
Semantic Scholar
Purification and molecular identification of the human hyaluronan receptor for endocytosis.
Bin Zhou, C. McGary, Janet A. Weigel, A. Saxena +1 more
2003Glycobiology63 citations
Semantic Scholar
Recombinant human hyaluronan synthase 3 is phosphorylated in mammalian cells.
Brian J. Goentzel, P. H. Weigel, R. A. Steinberg
2006Biochemical Journal59 citations Open access
Semantic Scholar
IgA induced activation of human mesangial cells: Independent of FcαR1 (CD 89)
S. Diven, C. R. Caflisch, D. Hammond, P. H. Weigel +2 more
199859 citations Open access
Semantic Scholar
What is special about 200 kDa hyaluronan that activates hyaluronan receptor signaling?
P. H. Weigel, B. Baggenstoss
2017Glycobiology55 citations Open access
Semantic Scholar
The Hyaluronan Receptor for Endocytosis Mediates Hyaluronan-dependent Signal Transduction via Extracellular Signal-regulated Kinases*
S. Kyosseva, E. Harris, P. H. Weigel
2008Journal of Biological Chemistry53 citations Open access
Semantic Scholar
Hyaluronan synthase control of synthesis rate and hyaluronan product size are independent functions differentially affected by mutations in a conserved tandem B-X7-B motif
B. Baggenstoss, E. Harris, Jennifer L. Washburn, Andria P. Medina +2 more
2017Glycobiology51 citations Open access
Semantic Scholar
Characterization of the Recombinant Rat 175-kDa Hyaluronan Receptor for Endocytosis (HARE)*
Janet A. Weigel, P. H. Weigel
2003Journal of Biological Chemistry51 citations Open access
Semantic Scholar
Size exclusion chromatography-multiangle laser light scattering analysis of hyaluronan size distributions made by membrane-bound hyaluronan synthase.
B. Baggenstoss, P. H. Weigel
2006Analytical Biochemistry50 citations
Semantic Scholar
A TLR/AKT/FoxO3 immune tolerance–like pathway disrupts the repair capacity of oligodendrocyte progenitors
Taasin Srivastava, Parham Diba, J. Dean, F. Banine +11 more
2018Journal of Clinical Investigation49 citations Open access
Semantic Scholar
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Amplifies Hyaluronan Synthesis by Airway Smooth Muscle Cells*
Mark E. Lauer, Georgiana Cheng, S. Swaidani, M. Aronica +2 more
2012Journal of Biological Chemistry47 citations Open access
Semantic Scholar
Hyaluronic Acid Receptor for Endocytosis (HARE)-mediated Endocytosis of Hyaluronan, Heparin, Dermatan Sulfate, and Acetylated Low Density Lipoprotein (AcLDL), but Not Chondroitin Sulfate Types A, C, D, or E, Activates NF-κB-regulated Gene Expression*
Madhu S. Pandey, P. H. Weigel
2013Journal of Biological Chemistry46 citations Open access
Semantic Scholar
Inhibition of hyaluronan synthesis in Streptococcus equi FM100 by 4-methylumbelliferone.
I. Kakizaki, K. Takagaki, Y. Endo, Daisuke Kudo +8 more
2002European Journal of Biochemistry46 citations
Semantic Scholar
Rat and human HARE/stabilin-2 are clearance receptors for high- and low-molecular-weight heparins.
E. Harris, B. Baggenstoss, P. H. Weigel
2009American Journal of Physiology - Gastrointestinal and Liver Physiology44 citations Open access
Semantic Scholar
Human Intestinal Epithelial Cells Express a Novel Receptor for IgA1
T. Kitamura, R. Garofalo, Atsushi Kamijo, D. Hammond +6 more
2000Journal of Immunology43 citations
Semantic Scholar
Mutation of Two Intramembrane Polar Residues Conserved within the Hyaluronan Synthase Family Alters Hyaluronan Product Size*
K. Kumari, B. Baggenstoss, A. L. Parker, P. H. Weigel
2006Journal of Biological Chemistry42 citations Open access
Semantic Scholar
Injured brain endothelial cells release neurotoxic thrombin
P. Grammas, T. Ottman, U. Reimann‐Philipp, Jason L. Larabee +1 more
2004Journal of Alzheimer's Disease36 citations
Semantic Scholar
Hyaluronan synthase polymerizing activity and control of product size are discrete enzyme functions that can be uncoupled by mutagenesis of conserved cysteines.
P. H. Weigel, B. Baggenstoss
2012Glycobiology35 citations Open access
Semantic Scholar
Systemic blockade of the Hyaluronan Receptor for Endocytosis (HARE) prevents lymph node metastasis of prostate cancer
M. Simpson, Janet A. Weigel, P. H. Weigel
2012International Journal of Cancer34 citations Open access
Semantic Scholar
The hyaluronan receptor for endocytosis (HARE) is not CD44 or CD54 (ICAM-1).
Janet A. Weigel, R. C. Raymond, P. H. Weigel
2002Biochemical and Biophysical Research Communications - BBRC32 citations
Semantic Scholar
Discovery of the Liver Hyaluronan Receptor for Endocytosis (HARE) and Its Progressive Emergence as the Multi-Ligand Scavenger Receptor Stabilin-2
P. H. Weigel
2019Biomolecules29 citations Open access
Semantic Scholar
The Minor Subunit Splice Variants, H2b and H2c, of the Human Asialoglycoprotein Receptor Are Present with the Major Subunit H1 in Different Hetero-oligomeric Receptor Complexes*
Jasper H. N. Yik, A. Saxena, P. H. Weigel
2002Journal of Biological Chemistry28 citations Open access
Semantic Scholar
Hyaluronan synthase assembles chitin oligomers with -GlcNAc(α1→)UDP at the reducing end.
P. H. Weigel, C. West, Peng Zhao, L. Wells +2 more
2015Glycobiology27 citations Open access
Semantic Scholar
The Streptococcal Hyaluronan Synthases Are Inhibited by Sulfhydryl-modifying Reagents, but Conserved Cysteine Residues Are Not Essential for Enzyme Function*
K. Kumari, V. L. Tlapak-Simmons, B. Baggenstoss, P. H. Weigel
2002Journal of Biological Chemistry27 citations Open access
Semantic Scholar
New frontiers in medical sciences : redefining hyaluronan : proceedings of the symposium held in Padua, Italy, 17-19 June 1999
G. Abatangelo, P. H. Weigel
200027 citations
Semantic Scholar
Hyaluronan synthase assembles hyaluronan on a [GlcNAc(&bgr;1,4)]n-GlcNAc(&agr;1→)UDP primer and hyaluronan retains this residual chitin oligomer as a cap at the nonreducing end
P. H. Weigel, B. Baggenstoss, Jennifer L. Washburn
2017Glycobiology24 citations Open access
Semantic Scholar

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B. Baggenstoss — researcher profile on SciRah
Janet A. Weigel×11
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Janet A. Weigel — researcher profile on SciRah
E. Harris×10
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V. L. Tlapak-Simmons×7
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Bin Zhou — researcher profile on SciRah

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