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L. Wells · SciRah

Researcher profile · Semantic Scholar

L. Wells

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L. Wells — researcher profile on SciRah

h-index: 60
Works: 202
Citations: 13K

Most-cited papers

Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor
Peng Zhao, Jeremy Praissman, Oliver C. Grant, Yong-Fei Cai +12 more
2020Cell Host and Microbe306 citations Open access
Semantic Scholar
Quantification of the impact of the HIV-1-glycan shield on antibody elicitation
Tongqing Zhou, N. Doria-Rose, Cheng Cheng, G. Stewart-Jones +39 more
2017Cell Reports185 citations Open access
Semantic Scholar
Immunization expands HIV-1 V3-glycan specific B-cells in mice and macaques
A. Escolano, H. Gristick, M. Abernathy, Julia Merkenschlager +28 more
2019Nature144 citations Open access
Semantic Scholar
Glycan-Masking Focuses Immune Responses to the HIV-1 CD4-Binding Site and Enhances Elicitation of VRC01-Class Precursor Antibodies
Hong-Ying Duan, Xuejun Chen, J. Boyington, Cheng Cheng +17 more
2018Immunity141 citations Open access
Semantic Scholar
Oligosaccharyltransferase Inhibition Induces Senescence in RTK-Driven Tumor Cells
Cecilia Lopez-sambrooks, Shiteshu Shrimal, Carol Khodier, D. Flaherty +10 more
2016Nature Chemical Biology128 citations Open access
Semantic Scholar
MIRAGE: The minimum information required for a glycomics experiment
W. York, Sanjay Agravat, K. Aoki-Kinoshita, R. McBride +21 more
2014Glycobiology115 citations Open access
Semantic Scholar
The functional O-mannose glycan on α-dystroglycan contains a phospho-ribitol primed for matriglycan addition
Jeremy Praissman, T. Willer, M. O. Sheikh, A. Toi +12 more
2016eLife105 citations Open access
Semantic Scholar
Identification and characterization of a missense mutation in the O-linked β-N-acetylglucosamine (O-GlcNAc) transferase gene that segregates with X-linked intellectual disability
K. Vaidyanathan, T. Niranjan, N. Selvan, C. Teo +14 more
2017Journal of Biological Chemistry98 citations Open access
Semantic Scholar
Recent advancements in understanding mammalian O-mannosylation.
M. O. Sheikh, Stephanie M. Halmo, L. Wells
2017Glycobiology96 citations Open access
Semantic Scholar
The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting glycan microarray-based data
Yan Liu, R. McBride, M. Stoll, A. Palma +24 more
2016Glycobiology95 citations Open access
Semantic Scholar
B4GAT1 is the priming enzyme for the LARGE-dependent functional glycosylation of α-dystroglycan
Jeremy Praissman, D. Live, Shuo Wang, A. Ramiah +4 more
2014eLife89 citations Open access
Semantic Scholar
Distinct roles of N- and O-glycans in cellulase activity and stability
A. Amore, B. Knott, N. Supekar, A. Shajahan +14 more
2017Proceedings of the National Academy of Sciences of the United States of America85 citations Open access
Semantic Scholar
One-Step Selective Exoenzymatic Labeling (SEEL) Strategy for the Biotinylation and Identification of Glycoproteins of Living Cells
Tiantian Sun, Seok-Ho Yu, Peng Zhao, Lu Meng +4 more
2016Journal of the American Chemical Society78 citations Open access
Semantic Scholar
O-Glycosylation regulates polarized secretion by modulating Tango1 stability
Li-Ping Zhang, Zulfeqhar A. Syed, Iris van Dijk Härd, Jae-Min Lim +2 more
2014Proceedings of the National Academy of Sciences of the United States of America74 citations Open access
Semantic Scholar
The minimum information required for a glycomics experiment (MIRAGE) project: sample preparation guidelines for reliable reporting of glycomics datasets.
W. Struwe, Sanjay Agravat, K. Aoki-Kinoshita, Matthew P. Campbell +21 more
2016Glycobiology73 citations Open access
Semantic Scholar
Mammalian O-Mannosylation Pathway: Glycan Structures, Enzymes, and Protein Substrates
Jeremy Praissman, L. Wells
2014Biochemistry65 citations Open access
Semantic Scholar
An intellectual disability syndrome with single-nucleotide variants in O-GlcNAc transferase
V. Pravata, M. Omelková, Marios P. Stavridis, Chelsea M. Desbiens +9 more
2020European Journal of Human Genetics64 citations Open access
Semantic Scholar
Regulating the Regulators: Mechanisms of Substrate Selection of the O-GlcNAc cycling enzymes OGT and OGA.
H. Stephen, Trevor M. Adams, L. Wells
2021Glycobiology63 citations Open access
Semantic Scholar
O-GlcNAc transferase missense mutations linked to X-linked intellectual disability deregulate genes involved in cell fate determination and signaling
N. Selvan, Stephan N. George, F. Serajee, M. Shaw +10 more
2018Journal of Biological Chemistry60 citations Open access
Semantic Scholar
CRISPR/Cas9 and glycomics tools for Toxoplasma glycobiology
Elisabet Gas-Pascual, H. Ichikawa, M. O. Sheikh, M. I. Serji +6 more
2018Journal of Biological Chemistry58 citations Open access
Semantic Scholar
Three CRISPR-Cas immune effector complexes coexist in Pyrococcus furiosus
S. Majumdar, Peng Zhao, N. T. Pfister, M. Compton +6 more
2015RNA: A publication of the RNA Society50 citations Open access
Semantic Scholar
Cell-Surface Glyco-Engineering by Exogenous Enzymatic Transfer Using a Bifunctional CMP-Neu5Ac Derivative
Chantelle J. Capicciotti, Chengli Zong, M. O. Sheikh, Tiantian Sun +2 more
2017Journal of the American Chemical Society47 citations Open access
Semantic Scholar
O-GlcNAc transferase regulates transcriptional activity of human Oct4
S. Constable, Jae-Min Lim, K. Vaidyanathan, L. Wells
2017Glycobiology46 citations Open access
Semantic Scholar
The translocon-associated protein (TRAP) complex regulates quality control of N-linked glycosylation during ER stress
C. Phoomak, W. Cui, T. Hayman, Seok-Ho Yu +4 more
2021Science Advances41 citations Open access
Semantic Scholar
Identification of a novel base J binding protein complex involved in RNA polymerase II transcription termination in trypanosomes
R. Kieft, Yang Zhang, Alexandre P. Marand, J. Moran +4 more
2019bioRxiv41 citations Open access
Semantic Scholar
Selective Exo-Enzymatic Labeling Detects Increased Cell Surface Sialoglycoprotein Expression upon Megakaryocytic Differentiation*
Seok-Ho Yu, Peng Zhao, Tiantian Sun, Zhongwei Gao +4 more
2016Journal of Biological Chemistry40 citations Open access
Semantic Scholar
The E3 Ubiquitin Ligase Adaptor Protein Skp1 Is Glycosylated by an Evolutionarily Conserved Pathway That Regulates Protist Growth and Development*♦
Kazi Rahman, Peng Zhao, Msano Mandalasi, H. van der Wel +3 more
2015Journal of Biological Chemistry40 citations Open access
Semantic Scholar
Cell surface glycan engineering reveals that matriglycan alone can recapitulate dystroglycan binding and function
M. O. Sheikh, Chantelle J. Capicciotti, Lin Liu, Jeremy Praissman +8 more
2021Nature Communications38 citations Open access
Semantic Scholar
Rapid screening of sugar-nucleotide donor specificities of putative glycosyltransferases
M. O. Sheikh, Stephanie M. Halmo, Sneha Patel, D. Middleton +7 more
2017Glycobiology38 citations Open access
Semantic Scholar
A shunt pathway limits the CaaX processing of Hsp40 Ydj1p and regulates Ydj1p-dependent phenotypes
Emily R. Hildebrandt, Michael Cheng, Peng Zhao, June-hyun Kim +2 more
2016eLife36 citations Open access
Semantic Scholar
Generation of an Interactome for the Tetratricopeptide Repeat Domain of O-GlcNAc Transferase Indicates a Role for the Enzyme in Intellectual Disability
H. Stephen, Jeremy Praissman, L. Wells
2020Journal of Proteome Research35 citations Open access
Semantic Scholar
Protein O-Linked Mannose β-1,4-N-Acetylglucosaminyl-transferase 2 (POMGNT2) Is a Gatekeeper Enzyme for Functional Glycosylation of α-Dystroglycan*
S. Halmo, Danish Singh, Sneha Patel, Shuo Wang +5 more
2016Journal of Biological Chemistry34 citations Open access
Semantic Scholar
O-Linked β-N-acetylglucosamine (O-GlcNAc) Acts as a Glucose Sensor to Epigenetically Regulate the Insulin Gene in Pancreatic Beta Cells*
Sean P Durning, H. Flanagan-Steet, Nripesh Prasad, L. Wells
2015Journal of Biological Chemistry33 citations Open access
Semantic Scholar
Structural Analysis of Glycosylated Intact HIV-1 gp120-b12 Antibody Complex using Hydroxyl Radical Protein Footprinting
Xiaoyan Li, Oliver C. Grant, Keigo Ito, A. Wallace +6 more
2017Biochemistry31 citations Open access
Semantic Scholar
Quantitative secretome and glycome of primary human adipocytes during insulin resistance
Jae-Min Lim, Edith E. Wollaston-Hayden, C. Teo, D. Hausman +1 more
2014Clinical Proteomics30 citations Open access
Semantic Scholar
Selective inhibition of N-linked glycosylation impairs receptor tyrosine kinase processing
Elsenoor Klaver, Peng Zhao, M. May, H. Flanagan-Steet +5 more
2019Disease Models & Mechanisms29 citations Open access
Semantic Scholar
Human UDP-galactose 4′-epimerase (GALE) is required for cell-surface glycome structure and function
Alex Broussard, Alyssa Florwick, Chelsea M. Desbiens, Nicole Nischan +5 more
2019Journal of Biological Chemistry27 citations Open access
Semantic Scholar
Exploiting glycan topography for computational design of Env glycoprotein antigenicity
Wen-Han Yu, Peng Zhao, M. Draghi, C. Arevalo +11 more
2018PLoS Comput. Biol.27 citations Open access
Semantic Scholar
Hyaluronan synthase assembles chitin oligomers with -GlcNAc(α1→)UDP at the reducing end.
P. H. Weigel, C. West, Peng Zhao, L. Wells +2 more
2015Glycobiology27 citations Open access
Semantic Scholar
Glycosylation Is Vital for Industrial Performance of Hyperactive Cellulases
D. Chung, N. Sarai, B. Knott, N. Hengge +14 more
2019ACS Sustainable Chemistry and Engineering24 citations Open access
Semantic Scholar
Proteomics-based screening of the endothelial heparan sulfate interactome reveals that C-type lectin 14a (CLEC14A) is a heparin-binding protein
Daniel R. Sandoval, Alejandro Gomez Toledo, Chelsea D. Painter, E. Tota +8 more
2020Journal of Biological Chemistry23 citations Open access
Semantic Scholar
Secretomic Insight into Glucose Metabolism of Aspergillus brasiliensis in Solid-State Fermentation.
T. Volke-Sepúlveda, Daniel Salgado-Bautista, C. Bergmann, L. Wells +2 more
2016Journal of Proteome Research23 citations
Semantic Scholar
Characterization of a cytoplasmic glucosyltransferase that extends the core trisaccharide of the Toxoplasma Skp1 E3 ubiquitin ligase subunit
Kazi Rahman, Msano Mandalasi, Peng Zhao, M. O. Sheikh +8 more
2017Journal of Biological Chemistry20 citations Open access
Semantic Scholar
Rapid screening of sugar-nucleotide donor specificities of putative glycosyltransferases.
M. O. Sheikh, S. Halmo, Sneha Patel, D. Middleton +7 more
2016Glycobiology20 citations
Semantic Scholar
Global O-GlcNAc Levels Modulate Transcription of the Adipocyte Secretome during Chronic Insulin Resistance
Edith E. Wollaston-Hayden, R. Harris, Bingqiang Liu, R. Bridger +2 more
2015Frontiers in Endocrinology20 citations Open access
Semantic Scholar
Proteomics-Based Insights Into the SARS-CoV-2–Mediated COVID-19 Pandemic: A Review of the First Year of Research
Jeremy Praissman, L. Wells
2021Molecular & Cellular Proteomics17 citations Open access
Semantic Scholar
HNK-1 Sulfotransferase modulates α-dystroglycan glycosylation by 3-O-sulfation of glucuronic acid on matriglycan.
M. O. Sheikh, D. Venzke, Mary E. Anderson, Takako Yoshida-Moriguchi +6 more
2020Glycobiology14 citations Open access
Semantic Scholar
Separation and Identification of Permethylated Glycan Isomers by Reversed Phase NanoLC-NSI-MSn
Simone Kurz, M. O. Sheikh, Sha-Ne Lu, L. Wells +1 more
2020Molecular & Cellular Proteomics14 citations Open access
Semantic Scholar
Glycan Profiles of gp120 Protein Vaccines from Four Major HIV-1 Subtypes Produced from Different Host Cell Lines under Non-GMP or GMP Conditions
Shi-Xia Wang, Yegor A. Voronin, Peng Zhao, M. Ishihara +9 more
2020Journal of Virology13 citations Open access
Semantic Scholar
Identification and characterization of the Streptococcus pneumoniae type 3 capsule-specific glycoside hydrolase of Paenibacillus species 32352
D. Middleton, Xing Zhang, Paeton L. Wantuch, A. Ozdilek +7 more
2018Glycobiology13 citations Open access
Semantic Scholar

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