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J. Vičar · SciRah

Researcher profile · Semantic Scholar

J. Vičar

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J. Vičar — researcher profile on SciRah

h-index: 23
Works: 60
Citations: 1,652

Most-cited papers

Biological activities of Prunella vulgaris extract
J. Psotová, M. Kolář, J. Sousek, Z. Švagera +2 more
2003Phytotherapy Research184 citations
Semantic Scholar
Sanguinarine and chelerythrine: assessment of safety on pigs in ninety days feeding experiment.
P. Kosina, D. Walterová, J. Ulrichová, V. Lichnovský +6 more
2004Food and Chemical Toxicology164 citations
Semantic Scholar
Metal-chelating properties, electrochemical behavior, scavenging and cytoprotective activities of six natural phenolics.
J. Psotová, J. Lasovský, J. Vičar
2003Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia100 citations Open access
Semantic Scholar
Silymarin: What is in the name …? An appeal for a change of editorial policy
V. Šimánek, V. Křen, J. Ulrichová, J. Vičar +1 more
2000Hepatology96 citations Open access
Semantic Scholar
Benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine: biological activities and dental care applications.
D. Walterová, J. Ulrichová, I. Válka, J. Vičar +6 more
1995Acta Universitatis Palackianae Olomucensis Facultatis Medicae90 citations
Semantic Scholar
Cytotoxicity of natural compounds in hepatocyte cell culture models. The case of quaternary benzo[c]phenanthridine alkaloids.
J. Ulrichová, Z. Dvořák, J. Vičar, Jan Lata +3 more
2001Toxicology Letters72 citations
Semantic Scholar
Chelerythrine and dihydrochelerythrine induce G1 phase arrest and bimodal cell death in human leukemia HL-60 cells.
J. Vrba, P. Doležel, J. Vičar, M. Modriansky +1 more
2008Toxicology in Vitro69 citations
Semantic Scholar
Natural feed additive of Macleaya cordata: safety assessment in rats a 90-day feeding experiment.
A. Zdařilová, E. Vrublová, J. Vostálová, B. Klejdus +10 more
2008Food and Chemical Toxicology62 citations
Semantic Scholar
A liquid chromatographic-mass spectrometric evidence of dihydrosanguinarine as a first metabolite of sanguinarine transformation in rat.
J. Psotová, B. Klejdus, R. Večeřa, P. Kosina +4 more
2006Journal of chromatography. B, Analytical technologies in the biomedical and life sciences61 citations
Semantic Scholar
Cytotoxic activity of sanguinarine and dihydrosanguinarine in human promyelocytic leukemia HL-60 cells.
J. Vrba, P. Doležel, J. Vičar, J. Ulrichová
2009Toxicology in Vitro60 citations
Semantic Scholar
Quaternary Benzo[c]phenanthridines Sanguinarine and Chelerythrine: A Review of Investigations from Chemical and Biological Studies
Z. Dvořák, V. Kuban, B. Klejdus, J. Hlaváč +3 more
200655 citations Open access
Semantic Scholar
Quaternary benzo[c]phenanthridine alkaloids as inhibitors of aminopeptidase N and dipeptidyl peptidase IV
A. Sedo, K. Vlasicová, P. Barták, R. Vespalec +3 more
2002Phytotherapy Research43 citations Open access
Semantic Scholar
Chromatographic determination of constituents of the genus Colchicum (Liliaceae)
P. Ondra, I. Válka, J. Vičar, N. Sütlüpinar +1 more
199540 citations
Semantic Scholar
Amino acids and peptides. CXIV. Proton magnetic reasonance studies of cyclodipeptides containing pipecolic acid, proline and/or 2-azetidinecarboxylic acid
J. Vičar, M. Buděšínský, K. Bláha
197340 citations
Semantic Scholar
Cytochemical and biochemical evidence of cathepsin B in malignant, transformed and normal breast epithelial cells.
E. Křepela, Jiri Bartek, D. Skalková, J. Vičar +3 more
1987Journal of Cell Science36 citations
Semantic Scholar
The toxicity and pharmacokinetics of dihydrosanguinarine in rat: a pilot study.
E. Vrublová, J. Vostálová, R. Večeřa, B. Klejdus +10 more
2008Food and Chemical Toxicology35 citations
Semantic Scholar
Quaternary Benzo[C]Phenanthridine Alkaloids — Biological Activities
V. Šimánek, R. Vespalec, A. Sedo, J. Ulrichová +1 more
200331 citations
Semantic Scholar
Cathepsin B in human breast tumor tissue and cancer cells.
E. Křepela, J. Vičar, M. Černoch
1989Neoplasma (Bratislava)30 citations
Semantic Scholar
Safety assessment of sanguiritrin, alkaloid fraction of Macleaya cordata, in rats
J. Psotová, R. Večeřa, A. Zdařilová, E. Anzenbacherová +9 more
201828 citations Open access
Semantic Scholar
The two conformations of TRH in solution
J. Vičar, E. Abillon, F. Toma, F. Piriou +4 more
1979FEBS Letters26 citations Open access
Semantic Scholar
Capillary electrophoretic determination of sanguinarine and chelerythrine in plant extracts and pharmaceutical preparations.
J. Ševčı́k, J. Vičar, J. Ulrichová, I. Válka +2 more
2000Journal of Chromatography A25 citations
Semantic Scholar
Synthesis and properties of tuftsin, L-threonyl-L-lysil-L-prolyl-L-arginine
J. Vičar, V. Gut, I. Frič, K. Bláha
197625 citations
Semantic Scholar
Macleya cordata and Prunella vulgaris in oral hygiene products - their efficacy in the control of gingivitis.
H. Adámková, J. Vičar, Jirina Palasová, J. Ulrichová +1 more
2004Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia24 citations Open access
Semantic Scholar
Amino acids and peptides. CXV. 2,5-Piperazinediones with an anneled azetidine ring; Synthesis and infrared spectra
J. Vičar, J. Smolíková, K. Bláha
197322 citations
Semantic Scholar
Amino acids and peptides. CIX. Synthesis and infrared spectroscopy of 2,5-piperazinediones derived from proline and pipecolic acid
J. Vičar, J. Smolíková, K. Bláha
197218 citations
Semantic Scholar
Capillary zone electrophoretic studies of interactions of some quaternary isoquinoline alkaloids with DNA constituents and DNA
M. Vlčková, V. Kuban, J. Vičar, V. Šimánek
2005Electrophoresis16 citations
Semantic Scholar
Spectroscopic studies of cyclodipeptides containing pipecolic acid, proline and/or 2-azetidinecarboxylic acid
K. Bláha, M. Buděšínský, I. Frič, J. Smolíková +1 more
197216 citations
Semantic Scholar
Demonstration of two molecular forms of dipeptidyl peptidase IV in normal human serum.
E. Křepela, J. Kraml, J. Vičar, L. Kadlecová +1 more
1983Physiologia Bohemoslovaca15 citations
Semantic Scholar
Synthesis of isodecarine
J. Hlaváč, J. Stýskala, Petr Cankař, Miroslav Soural +3 more
200712 citations Open access
Semantic Scholar
Sanguinarine activates polycyclic aromatic hydrocarbon associated metabolic pathways in human oral keratinocytes and tissues.
Z. Dvořák, M. Modriansky, V. Šimánek, J. Ulrichová +3 more
2005Toxicology Letters12 citations
Semantic Scholar
An assay of dipeptidyl peptidase IV activity in human serum and serum of pregnant women with glycyl-L-proline-1-naphthylamide and other glycyl-L-proline-arylamides as substrates.
E. Křepela, E. Kasafírek, J. Vičar, J. Kraml
1983Physiologia Bohemoslovaca12 citations
Semantic Scholar
Acid-base behaviour of sanguinarine and dihydrosanguinarine
Helena Absolínová, L. Jančář, I. Jančářová, J. Vičar +1 more
200911 citations Open access
Semantic Scholar
Electrochemistry of Benzophenanthridine Alkaloids. Formation and Characterization of Redox Active Films from Products of Sanguinarine and Chelerythrine Oxidation
J. Hrbáč, G. Broncová, P. Matějka, Tomáš Bystroň +3 more
200511 citations
Semantic Scholar
Amino acids and peptides. CXVI. Conformational factors in the isomerisation of cyclodipeptides
J. Vičar, K. Bláha
197311 citations
Semantic Scholar
Conformational studies of diastereoisomeric cyclo(alanyl‐phenylalanyl) with the coupling constants 1H–1H, 15N–1H, 13C–1H, and 13C–15N
J. Vičar, K. Bláha, F. Piriou, M. Juy +2 more
198210 citations
Semantic Scholar
Spectrophotometric study of time stability and acid-base characteristics of chelerythrine and dihydrochelerythrine
Helena Absolínová, L. Jančář, I. Jančářová, J. Vičar +1 more
20109 citations Open access
Semantic Scholar
Study of the inhibition of α-amylase by the benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine
L. Zajoncová, P. Kosina, J. Vičar, J. Ulrichová +1 more
2005Journal of Enzyme Inhibition and Medicinal Chemistry9 citations Open access
Semantic Scholar
Changes in colchicine and demecolcine content during vegetation period of colchicum autumnale L.
J. Vičar, L. Klusáková, V. Šimánek
1993Acta Universitatis Palackianae Olomucensis Facultatis Medicae9 citations
Semantic Scholar
Cathepsin B in cells of two rat sarcomas with different rates of spontaneous metastasis.
E. Křepela, P. Veselý, A. Chaloupková, D. Zicha +3 more
1989Neoplasma (Bratislava)9 citations
Semantic Scholar
13 C nuclear magnetic resonance study of cyclodipeptides containing 13 C enriched hydrophobic amino acids
J. Vičar, F. Piriou, P. Fromageot, K. Bláha +1 more
19809 citations
Semantic Scholar
Synthesis and spectral properties of cyclotripeptides containing 2-azetidinecarboxylic acid or proline
J. Vičar, P. Maloň, A. Trka, J. Smolíková +2 more
19779 citations
Semantic Scholar
A latent form of cathepsin B in pleural effusions. I. Characterization of the enzyme in breast cancer patients.
D. Petrová-Skalková, E. Křepela, D. Rasnick, J. Vičar
1987Biochemical Medicine and Metabolic Biology8 citations
Semantic Scholar
The influence of organic solvents on the conformation of thyreotropin releasing factor (TRF) studied by circular dichroism
P. Pradeles, J. Vičar, J. L. Morgat, S. Fermandjian +2 more
19778 citations
Semantic Scholar
13C‐13C couplings in 13C‐labeled cyclo (tri‐L‐prolyl) and the pyrrolidine ring conformation
J. Vičar, K. Bláha, F. Piriou, P. Fromageot +1 more
19797 citations Open access
Semantic Scholar
Clinical experience with the testing of serum proteinase activity by cathepsin B-like sensitive amino acid derivatives of 7-amino-4-methylcoumarine.
Z. Kolář, E. Křepela, J. Kovarik, M. Kohoutek +2 more
1987Neoplasma (Bratislava)4 citations
Semantic Scholar
["Silymarin"--an extract from the milk thistle (Silybum marianum)--is it a drug or nutritional supplement?].
V. Šimánek, D. Walterová, J. Vičar, J. Urbaníková +4 more
2001Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti3 citations
Semantic Scholar
Autoprotolysis constants and activity ratios of the lyate ions in water-alcohol mixtures
J. Mollin, Z. Pavelek, A. Schneiderová, J. Vičar +2 more
19833 citations
Semantic Scholar
Separation of Quaternary Benzo[c]phenanthridine Alkaloids from Macleaya cordata
J. Vičar, Miroslav Soural, J. Hlaváč
20101 citations
Semantic Scholar
Changes in tissue and serum activity of cathepsin B-like cysteine proteinase during colorectal carcinogenesis by 1,2-dimethylhydrazine in mice.
Z. Kolář, V. Dufek, E. Křepela, J. Vičar +1 more
1985Neoplasma (Bratislava)1 citations
Semantic Scholar
Synthesis of γ-L-glutamyl-glycyl-glycine - A substrate for γ-glutamyl transferase
J. Vičar, J. Bartousek
19781 citations
Semantic Scholar

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V. Šimánek×20
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V. Šimánek — researcher profile on SciRah
J. Ulrichová×19
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J. Ulrichová — researcher profile on SciRah
K. Bláha×12
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K. Bláha — researcher profile on SciRah
E. Křepela×8
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E. Křepela — researcher profile on SciRah

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P. Kosina — researcher profile on SciRah

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V. Kuban — researcher profile on SciRah

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J. Psotová — researcher profile on SciRah

D. Walterová×4

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D. Walterová — researcher profile on SciRah

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Z. Dvořák — researcher profile on SciRah

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J. Vrba — researcher profile on SciRah

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B. Klejdus — researcher profile on SciRah