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E. Anzenbacherová · SciRah

Researcher profile · Semantic Scholar

E. Anzenbacherová

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E. Anzenbacherová — researcher profile on SciRah

h-index: 29
Works: 124
Citations: 4,546

Most-cited papers

Phase II drug metabolizing enzymes.
P. Jančová, P. Anzenbacher, E. Anzenbacherová
2010Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia578 citations Open access
Semantic Scholar
Isothiocyanate from Broccoli, Sulforaphane, and Its Properties
A. Vanduchová, P. Anzenbacher, E. Anzenbacherová
2019Journal of Medicinal Food286 citations Open access
Semantic Scholar
Valproic Acid Induces CYP3A4 and MDR1 Gene Expression by Activation of Constitutive Androstane Receptor and Pregnane X Receptor Pathways
L. Červený, Lucie Švecová, E. Anzenbacherová, R. Vrzal +5 more
2007Drug Metabolism And Disposition226 citations
Semantic Scholar
What common structural features and variations of mammalian P450s are known to date?
M. Otyepka, J. Skopalík, E. Anzenbacherová, P. Anzenbacher
2007Biochimica et Biophysica Acta139 citations
Semantic Scholar
Administration of a Probiotic Can Change Drug Pharmacokinetics: Effect of E. coli Nissle 1917 on Amidarone Absorption in Rats
Z. Matúšková, E. Anzenbacherová, R. Večeřa, H. Tlaskalova-Hogenova +2 more
2014PLoS ONE90 citations Open access
Semantic Scholar
JNK inhibitor SP600125 is a partial agonist of human aryl hydrocarbon receptor and induces CYP1A1 and CYP1A2 genes in primary human hepatocytes.
Z. Dvořák, R. Vrzal, Pavla Henklová, P. Jančová +9 more
2008Biochemical Pharmacology78 citations
Semantic Scholar
Silybin Is Metabolized by Cytochrome P450 2C8 in Vitro
P. Jančová, E. Anzenbacherová, Barbora Papoušková, K. Lemr +4 more
2007Drug Metabolism And Disposition78 citations
Semantic Scholar
Flexibility of human cytochrome P450 enzymes: molecular dynamics and spectroscopy reveal important function-related variations.
Tereza Hendrychová, E. Anzenbacherová, J. Hudeček, J. Skopalík +4 more
2011Biochimica et Biophysica Acta72 citations
Semantic Scholar
SB203580, a pharmacological inhibitor of p38 MAP kinase transduction pathway activates ERK and JNK MAP kinases in primary cultures of human hepatocytes.
Pavla Henklová, R. Vrzal, Barbora Papoušková, P. Bednář +6 more
2008European Journal of Pharmacology68 citations
Semantic Scholar
Human gut microbiota plays a role in the metabolism of drugs.
Lenka Jourová, P. Anzenbacher, E. Anzenbacherová
2016Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia65 citations Open access
Semantic Scholar
Azole Antimycotics Differentially Affect Rifampicin-Induced Pregnane X Receptor-Mediated CYP3A4 Gene Expression
Lucie Švecová, R. Vrzal, L. Burýšek, E. Anzenbacherová +9 more
2008Drug Metabolism And Disposition62 citations
Semantic Scholar
Antioxidant effects of coumarins include direct radical scavenging, metal chelation and inhibition of ROS-producing enzymes.
T. Filipský, M. Říha, K. Macáková, E. Anzenbacherová +2 more
2015Current Topics in Medicinal Chemistry52 citations
Semantic Scholar
Pelargonidin activates the AhR and induces CYP1A1 in primary human hepatocytes and human cancer cell lines HepG2 and LS174T
Alzbeta Kamenickova, E. Anzenbacherová, P. Pávek, A. Soshilov +3 more
2013Toxicology Letters50 citations Open access
Semantic Scholar
Interaction of isoflavonoids with human liver microsomal cytochromes P450: inhibition of CYP enzyme activities
M. Kopečná-Zapletalová, Kristýna Krasulová, P. Anzenbacher, P. Hodek +1 more
2017Xenobiotica; the fate of foreign compounds in biological systems44 citations
Semantic Scholar
Evidence for differences in regioselective and stereoselective glucuronidation of silybin diastereomers from milk thistle (Silybum marianum) by human UDP-glucuronosyltransferases
P. Jančová, M. Šiller, E. Anzenbacherová, V. Křen +2 more
2011Xenobiotica; the fate of foreign compounds in biological systems42 citations
Semantic Scholar
Model systems based on experimental animals for studies on drug metabolism in man: (mini)pig cytochromes P450 3A29 and 2E1.
E. Anzenbacherová, J. Baranová, R. Zuber, A. Pechová +3 more
2005Basic & Clinical Pharmacology & Toxicology37 citations Open access
Semantic Scholar
Porcine CYP2A19, CYP2E1 and CYP1A2 forms are responsible for skatole biotransformation in the reconstituted system.
J. Matal, Z. Matúšková, A. Tunkova, E. Anzenbacherová +1 more
2009Neuro - endocrinology letters33 citations
Semantic Scholar
Butyrate, a typical product of gut microbiome, affects function of the AhR gene, being a possible agent of crosstalk between gut microbiome and hepatic drug metabolism.
Lenka Jourová, E. Anzenbacherová, Z. Dostál, P. Anzenbacher +4 more
2022Journal of Nutritional Biochemistry32 citations Open access
Semantic Scholar
Effects of anthocyanins on the AhR-CYP1A1 signaling pathway in human hepatocytes and human cancer cell lines
Alzbeta Kamenickova, E. Anzenbacherová, P. Pávek, A. Soshilov +4 more
2013Toxicology Letters31 citations Open access
Semantic Scholar
Effects of anthocyanidins and anthocyanins on the expression and catalytic activities of CYP2A6, CYP2B6, CYP2C9, and CYP3A4 in primary human hepatocytes and human liver microsomes.
Alžběta Srovnalová, M. Švécarová, M. Zapletalová, P. Anzenbacher +3 more
2014Journal of Agricultural and Food Chemistry30 citations
Semantic Scholar
Gut Microbiome Alters the Activity of Liver Cytochromes P450 in Mice With Sex-Dependent Differences
Lenka Jourová, M. Vavrečková, N. Zemanová, P. Anzenbacher +4 more
2020Frontiers in Pharmacology29 citations Open access
Semantic Scholar
Effects of Lactobacillus casei on the expression and the activity of cytochromes P450 and on the CYP mRNA level in the intestine and the liver of male rats.
Z. Matúšková, M. Šiller, A. Tunkova, E. Anzenbacherová +4 more
2011Neuro - endocrinology letters29 citations
Semantic Scholar
Safety assessment of sanguiritrin, alkaloid fraction of Macleaya cordata, in rats
J. Psotová, R. Večeřa, A. Zdařilová, E. Anzenbacherová +9 more
201828 citations Open access
Semantic Scholar
Altered cytochrome P450 activities and expression levels in the liver and intestines of the monosodium glutamate-induced mouse model of human obesity.
V. Tománková, B. Líšková, L. Skálová, H. Bártíková +5 more
2015Life Science28 citations
Semantic Scholar
Gut microbiome affects the metabolism of metronidazole in mice through regulation of hepatic cytochromes P450 expression
N. Zemanová, K. Lněničková, M. Vavrečková, E. Anzenbacherová +6 more
2021PLoS ONE27 citations Open access
Semantic Scholar
Interaction of antitumor platinum complexes with human liver microsomal cytochromes P450
Vlastimil Mašek, E. Anzenbacherová, M. Machová, V. Brabec +1 more
2009Anti-Cancer Drugs26 citations
Semantic Scholar
Effects of obesity on liver cytochromes P450 in various animal models.
V. Tománková, P. Anzenbacher, E. Anzenbacherová
2017Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia25 citations Open access
Semantic Scholar
Inhibition of human liver microsomal cytochrome P450 activities by adefovir and tenofovir
J. Nekvindová, Vlastimil Mašek, Alena Veinlichová, E. Anzenbacherová +3 more
2006Xenobiotica; the fate of foreign compounds in biological systems25 citations
Semantic Scholar
Interspecies comparison of the glucuronidation processes in the man, monkey, pig, dog and rat.
J. Matal, P. Jančová, M. Šiller, Vlastimil Mašek +2 more
2008Neuro - endocrinology letters22 citations
Semantic Scholar
Colonization by non-pathogenic bacteria alters mRNA expression of cytochromes P450 in originally germ-free mice
Lenka Jourová, Pavel Anzenbacher, Barbora Lišková, Z. Matúšková +5 more
2017Folia Microbiologica (Prague)20 citations
Semantic Scholar
The role of cytochromes P450 in metabolism of selected antidepressants and anxiolytics under psychological stress.
N. Zemanová, P. Anzenbacher, E. Anzenbacherová
2022Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia19 citations Open access
Semantic Scholar
Butyrate Treatment of DSS-Induced Ulcerative Colitis Affects the Hepatic Drug Metabolism in Mice
Lenka Jourová, S. Satka, V. Frybortova, I. Zapletalová +7 more
2022Frontiers in Pharmacology18 citations Open access
Semantic Scholar
Gut microbiota metabolizes nabumetone in vitro: Consequences for its bioavailability in vivo in the rodents with altered gut microbiome
Lenka Jourová, P. Anzenbacher, Z. Matúšková, R. Večeřa +8 more
2019Xenobiotica; the fate of foreign compounds in biological systems18 citations
Semantic Scholar
Effect of Lactobacillus casei on the Pharmacokinetics of Amiodarone in Male Wistar Rats
Z. Matúšková, P. Anzenbacher, R. Večeřa, M. Šiller +3 more
2017European journal of drug metabolism and pharmacokinetics18 citations
Semantic Scholar
Influence of diet supplementation with green tea extract on drug-metabolizing enzymes in a mouse model of monosodium glutamate-induced obesity
I. Boušová, P. Matoušková, H. Bártíková, B. Szotáková +6 more
2016European Journal of Nutrition18 citations
Semantic Scholar
Binding of quinidine radically increases the stability and decreases the flexibility of the cytochrome P450 2D6 active site.
K. Berka, E. Anzenbacherová, Tereza Hendrychová, R. Lange +3 more
2012Journal of Inorganic Biochemistry17 citations
Semantic Scholar
The role of the microbiome and psychosocial stress in the expression and activity of drug metabolizing enzymes in mice
N. Zemanová, P. Anzenbacher, I. Zapletalová, Lenka Jourová +6 more
2020Scientific Reports16 citations Open access
Semantic Scholar
Rosuvastatin suppresses the liver microsomal CYP2C11 and CYP2C6 expression in male Wistar rats
A. Zachařová, M. Šiller, A. Špičáková, E. Anzenbacherová +3 more
2012Xenobiotica; the fate of foreign compounds in biological systems16 citations
Semantic Scholar
In vivo evaluation of effect of anthocyanin-rich wheat on rat liver microsomal drug-metabolizing cytochromes P450 and on biochemical and antioxidant parameters in rats.
J. Prokop, P. Anzenbacher, E. Mrkvicová, L. Pavlata +5 more
2018Food and Chemical Toxicology15 citations
Semantic Scholar
Effects of sulforaphane and its S- and R-enantiomers on the expression and activities of human drug-metabolizing cytochromes P450
Alžběta Srovnalová, A. Vanduchová, M. Švécarová, E. Anzenbacherová +3 more
201514 citations Open access
Semantic Scholar
Effects of probiotic Escherichia coli Nissle 1917 on expression of cytochromes P450 along the gastrointestinal tract of male rats.
Z. Matúšková, A. Tunkova, E. Anzenbacherová, R. Večeřa +4 more
2010Neuro - endocrinology letters14 citations
Semantic Scholar
Active Sites of Cytochromes P450: What are They Like?
P. Anzenbacher, E. Anzenbacherová, R. Lange, J. Skopalík +1 more
200814 citations
Semantic Scholar
Interaction of rocuronium with human liver cytochromes P450.
E. Anzenbacherová, A. Špičáková, Lenka Jourová, J. Ulrichová +3 more
2015Journal of Pharmacological Sciences13 citations Open access
Semantic Scholar
Performance, Biochemical Profile and Antioxidant Activity of Hens Supplemented with Addition of Milk Thistle (Silybum marianum) Seed Cakes in Diet
O. Šťastník, E. Mrkvicová, L. Pavlata, Andrea Roztočilová +2 more
2019Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis12 citations Open access
Semantic Scholar
Influence of Sulforaphane Metabolites on Activities of Human Drug-Metabolizing Cytochrome P450 and Determination of Sulforaphane in Human Liver Cells
A. Vanduchová, V. Tománková, P. Anzenbacher, E. Anzenbacherová
2016Journal of Medicinal Food12 citations
Semantic Scholar
Interaction of N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates with Human Liver Microsomal Cytochromes P450: Comparison with Free Doxorubicin
Vlastimil Mašek, E. Anzenbacherová, T. Etrych, J. Strohalm +2 more
2011Drug Metabolism And Disposition12 citations
Semantic Scholar
Effect of DSS-Induced Ulcerative Colitis and Butyrate on the Cytochrome P450 2A5: Contribution of the Microbiome
S. Satka, V. Frybortova, I. Zapletalová, P. Anzenbacher +5 more
2022International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
Effect of defined green tea extract in various dosage schemes on drug-metabolizing enzymes in mice in vivo
P. Matoušková, H. Bártíková, I. Boušová, B. Szotáková +8 more
201411 citations Open access
Semantic Scholar
Structural analysis of cytochromes P450 shows differences in flexibility of heme 2- and 4-vinyls.
J. Hudeček, P. Hodek, E. Anzenbacherová, P. Anzenbacher
2007Biochimica et Biophysica Acta10 citations
Semantic Scholar
Rapid Determination of Metronidazole and 2-Hydroxymetronidazole in Murine Blood Plasma.
N. Zemanová, P. Anzenbacher, T. Hudcovic, E. Anzenbacherová
2021Journal of Chromatographic Science9 citations
Semantic Scholar

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P. Anzenbacher×44
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P. Anzenbacher — researcher profile on SciRah
Lenka Jourová×11
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Lenka Jourová — researcher profile on SciRah
Z. Dvořák×8
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T. Hudcovic×8
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Z. Matúšková

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P. Jančová×6

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M. Šiller — researcher profile on SciRah

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