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L. Mangala · SciRah

Researcher profile · Semantic Scholar

L. Mangala

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L. Mangala — researcher profile on SciRah

h-index: 60
Works: 180
Citations: 12K

Most-cited papers

Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth
Li-Feng Yang, Abhinav Achreja, T. Yeung, L. Mangala +25 more
2016Cell Metabolism391 citations Open access
Semantic Scholar
RNA Interference–Based Therapy and Its Delivery Systems
Xiuhui Chen, L. Mangala, C. Rodríguez-Aguayo, Xian-Chao Kong +2 more
2017Cancer Metastasis Review281 citations Open access
Semantic Scholar
Platelets reduce anoikis and promote metastasis by activating YAP1 signaling
Monika Haemmerle, Morgan L. Taylor, T. Gutschner, S. Pradeep +22 more
2017Nature Communications248 citations Open access
Semantic Scholar
FABP4 as a key determinant of metastatic potential of ovarian cancer
K. Gharpure, S. Pradeep, Marta Sans, R. Rupaimoole +24 more
2018Nature Communications190 citations Open access
Semantic Scholar
JAK2-binding long noncoding RNA promotes breast cancer brain metastasis
Shou-Yu Wang, K. Liang, Qingsong Hu, Ping Li +21 more
2017Journal of Clinical Investigation185 citations Open access
Semantic Scholar
Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers
Yu-Meng Wang, Xiao-Yan Xu, Shuang-Xing Yu, K. Jeong +13 more
2017Genome Research160 citations Open access
Semantic Scholar
FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal.
Monika Haemmerle, J. Bottsford-Miller, S. Pradeep, Morgan L. Taylor +20 more
2016Journal of Clinical Investigation116 citations Open access
Semantic Scholar
Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance
Cecilia S. Leung, T. Yeung, Kay-Pong Yip, Kwong K. Wong +8 more
2017Journal of Clinical Investigation114 citations Open access
Semantic Scholar
Sustained adrenergic signaling promotes intratumoral innervation through BDNF induction
Julie K. Allen, G. Armaiz-Peña, A. Nagaraja, Nouara C. Sadaoui +31 more
2018Cancer Research113 citations Open access
Semantic Scholar
MYC targeted long non-coding RNA DANCR promotes cancer in part by reducing p21 levels
Yunqi Lu, Zhongyi Hu, L. Mangala, Zachary E. Stine +11 more
2017Cancer Research97 citations Open access
Semantic Scholar
Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression
R. Rupaimoole, C. Ivan, D. Yang, K. Gharpure +15 more
2016Oncogene89 citations Open access
Semantic Scholar
Macrophages facilitate resistance to anti-VEGF therapy by altered VEGFR expression
H. Dalton, S. Pradeep, Michael H. McGuire, Y. Hailemichael +21 more
2017Clinical Cancer Research87 citations Open access
Semantic Scholar
Bone protection by inhibition of microRNA-182
Kazuki Inoue, Zhonghao Deng, Yufan Chen, Eugenia G. Giannopoulou +9 more
2018Nature Communications79 citations Open access
Semantic Scholar
Role of Increased n-acetylaspartate Levels in Cancer.
B. Zand, R. Previs, N. Zacharias, R. Rupaimoole +29 more
2016Journal of the National Cancer Institute78 citations Open access
Semantic Scholar
Antiangiogenic and tumour inhibitory effects of downregulating tumour endothelial FABP4
Ulrike Harjes, E. Bridges, K. Gharpure, I. Roxanis +9 more
2016Oncogene77 citations Open access
Semantic Scholar
miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer
Deepak Parashar, Anjali Geethadevi, M. R. Aure, Jyotsna Mishra +20 more
2019Cell Reports76 citations Open access
Semantic Scholar
Therapeutic evaluation of microRNA-15a and microRNA-16 in ovarian cancer
S. Dwivedi, S. B. Mustafi, L. Mangala, Dahai Jiang +9 more
2016OncoTarget73 citations Open access
Semantic Scholar
Amendment history : Corrigendum ( November 2013 ) An anticancer C-Kit kinase inhibitor is reengineered to make it more active and less cardiotoxic
Ariel Fernández, A. Sanguino, Zhenghong Peng, E. Ozturk +16 more
201872 citations
Semantic Scholar
A-to-I-edited miRNA-379-5p inhibits cancer cell proliferation through CD97-induced apoptosis.
Xiao-Yan Xu, Yu-Meng Wang, K. Mojumdar, Zhi-Cheng Zhou +10 more
2019Journal of Clinical Investigation60 citations Open access
Semantic Scholar
TFEB ameliorates the impairment of the autophagy-lysosome pathway in neurons induced by doxorubicin
J. Moruno-Manchon, Ndidi-Ese Uzor, S. Kesler, J. Wefel +6 more
2016Aging60 citations Open access
Semantic Scholar
Adrenergic-mediated increases in INHBA drive CAF phenotype and collagens.
A. Nagaraja, R. Dood, G. Armaiz-Peña, Yu Kang +21 more
2017JCI Insight57 citations Open access
Semantic Scholar
Peroxisomes contribute to oxidative stress in neurons during doxorubicin-based chemotherapy
J. Moruno-Manchon, Ndidi-Ese Uzor, S. Kesler, J. Wefel +6 more
2017Molecular and cellular neurosciences54 citations Open access
Semantic Scholar
Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation
Yiyan Zheng, R. Sethi, L. Mangala, Charlotte L. Taylor +27 more
2018Nature Communications49 citations Open access
Semantic Scholar
Identifying and targeting angiogenesis-related microRNAs in ovarian cancer
Xiuhui Chen, L. Mangala, Linda K. Mooberry, E. Bayraktar +13 more
2019Oncogene47 citations Open access
Semantic Scholar
PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis
C. Rodríguez-Aguayo, E. Bayraktar, C. Ivan, Burcu Aslan +14 more
2019EBioMedicine44 citations Open access
Semantic Scholar
Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype
Shao-Lin Ma, Michael H. McGuire, L. Mangala, Sanghoon Lee +13 more
2021Cell Reports41 citations Open access
Semantic Scholar
Paclitaxel Sensitivity of Ovarian Cancer can be enhanced by knocking down Pairs of Kinases that regulate MAP4 Phosphorylation and Microtubule Stability
Hailing Yang, Wei-Qun Mao, C. Rodríguez-Aguayo, L. Mangala +8 more
2018Clinical Cancer Research40 citations Open access
Semantic Scholar
Differential effects of EGFL6 on tumor versus wound angiogenesis
Kyunghee Noh, L. Mangala, Hee D. Han, Ning-Yan Zhang +27 more
2017Cell Reports40 citations Open access
Semantic Scholar
CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance
Shao-Lin Ma, L. Mangala, Wen Hu, Emine Bayaktar +20 more
2021Cell Reports39 citations Open access
Semantic Scholar
ΔNp63/DGCR8-Dependent microRNAs Mediate Therapeutic Efficacy of HDAC Inhibitors in Cancer
M. Napoli, Avinashnarayan Venkatanarayan, Payal M. Raulji, B. Meyers +15 more
2016Cancer Cell37 citations Open access
Semantic Scholar
Combined VEGFR and MAPK pathway inhibition in angiosarcoma
M. Wagner, Y. Lyons, J. Siedel, R. Dood +9 more
2021Scientific Reports30 citations Open access
Semantic Scholar
PRKRA/PACT Expression Promotes Chemoresistance of Mucinous Ovarian Cancer
Takeshi Hisamatsu, Michael H. McGuire, S. Wu, R. Rupaimoole +21 more
2018Molecular Cancer Therapeutics30 citations Open access
Semantic Scholar
Quaking Orchestrates a Post-Transcriptional Regulatory Network of Endothelial Cell Cycle Progression Critical to Angiogenesis and Metastasis
S. Azam, A. Porrello, E. B. Harrison, P. Leslie +12 more
2019Oncogene28 citations Open access
Semantic Scholar
The hidden role of paxillin: localization to nucleus promotes tumor angiogenesis
Kyunghee Noh, Duc-Hiep Bach, H. Choi, Mark S Kim +11 more
2020Oncogene26 citations Open access
Semantic Scholar
Role of CTGF in sensitivity to hyperthermia in ovarian and uterine cancers
H. Hatakeyama, S. Wu, Y. Lyons, S. Pradeep +25 more
2016Cell Reports26 citations Open access
Semantic Scholar
Enhancing oral delivery of plant-derived vesicles for colitis
Yuan Liu, Adrian Lankenau Ahumada, E. Bayraktar, P. Schwartz +21 more
2023Journal of Controlled Release25 citations Open access
Semantic Scholar
ADH1B promotes mesothelial clearance and ovarian cancer infiltration
K. Gharpure, O. Lara, Yun-Fei Wen, S. Pradeep +9 more
2018OncoTarget25 citations Open access
Semantic Scholar
Chitosan Nanoparticles for miRNA Delivery
Merve Denizli, Burcu Aslan, L. Mangala, Dahai Jiang +3 more
2017Methods in molecular biology23 citations Open access
Semantic Scholar
Broad-Acting Therapeutic Effects of miR-29b-Chitosan on Hypertension and Diabetic Complications.
David M. Jensen, P. Han, L. Mangala, G. Lopez-Berestein +6 more
2022Molecular Therapy22 citations Open access
Semantic Scholar
Sustained Adrenergic Activation of YAP1 Induces Anoikis Resistance in Cervical Cancer Cells
Yang Li, Shanshan Yang, Nouara C. Sadaoui, Wei Hu +13 more
2020iScience20 citations Open access
Semantic Scholar
Targeting CCR2+ macrophages with BET inhibitor overcomes adaptive resistance to anti-VEGF therapy in ovarian cancer
Yutuan Wu, Nicholas B. Jennings, Yun-Jie Sun, S. Dasari +9 more
2022Journal of Cancer Research and Clinical Oncology19 citations Open access
Semantic Scholar
Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer
Noa Rabinowicz, L. Mangala, K. Brown, Cintia Checa-Rodríguez +16 more
2017OncoTarget17 citations Open access
Semantic Scholar
GnRH-R targeted lytic peptide sensitizes BRCA wild-type ovarian cancer to PARP inhibition
Shao-Lin Ma, S. Pradeep, Alejandro Villar-Prados, Yun-Fei Wen +12 more
2019Molecular Cancer Therapeutics15 citations Open access
Semantic Scholar
Activating p53 family member TAp63: A novel therapeutic strategy for targeting p53‐altered tumors
P. Gunaratne, Ying-Hong Pan, Abhi Rao, Chun-Ru Lin +17 more
2019Cancer15 citations Open access
Semantic Scholar
Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy.
L. Mangala, Hongyu Wang, Dahai Jiang, S. Wu +29 more
2016JCI Insight15 citations Open access
Semantic Scholar
Exploiting metabolic vulnerabilities after anti-VEGF antibody therapy in ovarian cancer
Deanna Glassman, Mark S Kim, Meredith Spradlin, Sunil P. Badal +22 more
2023iScience13 citations Open access
Semantic Scholar
JAK 2-binding long noncoding RNA promotes breast cancer brain metastasis
Shou-Yu Wang, K. Liang, Qingsong Hu, Ping Li +21 more
201913 citations
Semantic Scholar
Assessment of in vivo siRNA delivery in cancer mouse models
H. Hatakeyama, S. Wu, L. Mangala, G. Lopez-Berestein +1 more
2016Methods in molecular biology13 citations Open access
Semantic Scholar
Combination of EphA2- and Wee1-Targeted Therapies in Endometrial Cancer
S. Dasari, Robiya Joseph, Sujanitha Umamaheswaran, L. Mangala +13 more
2023International Journal of Molecular Sciences12 citations Open access
Semantic Scholar
MEK inhibition overcomes resistance to EphA2-targeted therapy in uterine cancer
Yutuan Wu, Jie Huang, C. Ivan, Yun-Jie Sun +9 more
2021Gynecologic Oncology12 citations Open access
Semantic Scholar

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