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Frank Kloprogge · SciRah

Researcher profile · Semantic Scholar

Frank Kloprogge

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Frank Kloprogge — researcher profile on SciRah

h-index: 11
Works: 40
Citations: 415

Most-cited papers

Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis
Frank Kloprogge, L. Workman, S. Borrmann, Mamadou M. Tekete +36 more
2018PLoS Medicine61 citations Open access
Semantic Scholar
Application of the hollow fibre infection model (HFIM) in antimicrobial development: a systematic review and recommendations of reporting
Z. Sadouki, Timothy D McHugh, R. Aarnoutse, Julio Ortiz Canseco +14 more
2021Journal of Antimicrobial Chemotherapy46 citations Open access
Semantic Scholar
Clinical Pharmacokinetics and Dose Recommendations for Posaconazole in Infants and Children
S. Boonsathorn, I. Cheng, Frank Kloprogge, C. Alonso +6 more
2018Clinical Pharmacokinetics46 citations Open access
Semantic Scholar
Systematic Review and Patient‐Level Meta‐Analysis of SARS‐CoV‐2 Viral Dynamics to Model Response to Antiviral Therapies
S. Gastine, J. Pang, F. Boshier, Simon J. Carter +6 more
2020medRxiv35 citations Open access
Semantic Scholar
Proposed Therapeutic Range of Treosulfan in Reduced Toxicity Pediatric Allogeneic Hematopoietic Stem Cell Transplant Conditioning: Results From a Prospective Trial
R. Chiesa, J. Standing, R. Winter, Z. Nademi +21 more
2019Clinical pharmacology and therapy33 citations Open access
Semantic Scholar
Revising Pediatric Vancomycin Dosing Accounting for Nephrotoxicity in a Pharmacokinetic-Pharmacodynamic Model
Frank Kloprogge, L. Hill, J. Booth, N. Klein +3 more
2019Antimicrobial Agents and Chemotherapy29 citations Open access
Semantic Scholar
Machine Learning and Artificial Intelligence in PK‐PD Modeling: Fad, Friend, or Foe?
Zhong-Hui Huang, P. Denti, Hitesh B. Mistry, Frank Kloprogge
2024Clinical pharmacology and therapy27 citations Open access
Semantic Scholar
Mimicking in-vivo exposures to drug combinations in-vitro: anti-tuberculosis drugs in lung lesions and the hollow fiber model of infection
Frank Kloprogge, R. Hammond, K. Kipper, S. Gillespie +1 more
2019Scientific Reports23 citations Open access
Semantic Scholar
An automated approach to identify scientific publications reporting pharmacokinetic parameters
Ferran Gonzalez Hernandez, Simon J. Carter, Juha Iso-Sipilä, P. Goldsmith +5 more
2021Wellcome Open Research17 citations Open access
Semantic Scholar
Improving the Drug Development Pipeline for Mycobacteria: Modelling Antibiotic Exposure in the Hollow Fibre Infection Model
Arundhati Maitra, P. Solanki, Z. Sadouki, Timothy D McHugh +1 more
2021Antibiotics15 citations Open access
Semantic Scholar
Longitudinal Pharmacokinetic-Pharmacodynamic Biomarkers Correlate With Treatment Outcome in Drug-Sensitive Pulmonary Tuberculosis: A Population Pharmacokinetic-Pharmacodynamic Analysis
Frank Kloprogge, H. Mwandumba, G. Banda, M. Kamdolozi +7 more
2020Open Forum Infectious Diseases15 citations Open access
Semantic Scholar
Named entity recognition of pharmacokinetic parameters in the scientific literature
Ferran Gonzalez Hernandez, Quang Nguyen, Victoria C. Smith, José A. Cordero +9 more
2024bioRxiv9 citations Open access
Semantic Scholar
Population pharmacokinetics and pharmacodynamics of investigational regimens’ drugs in the TB-PRACTECAL clinical trial (the PRACTECAL-PKPD study): a prospective nested study protocol in a randomised controlled trial
Bern-Thomas Nyang'wa, Frank Kloprogge, D. Moore, A. Bustinduy +3 more
2021BMJ Open9 citations Open access
Semantic Scholar
Comparative assessment of viral dynamic models for SARS‐CoV‐2 for pharmacodynamic assessment in early treatment trials
A. A. Agyeman, Tao You, P. Chan, D. Lonsdale +8 more
2022British Journal of Clinical Pharmacology7 citations Open access
Semantic Scholar
The impact of alcohol and illicit substance use on the pharmacokinetics of first-line TB drugs
Marie Wijk, K. Gausi, S. Malatesta, Sarah E Weber +13 more
2024Journal of Antimicrobial Chemotherapy6 citations Open access
Semantic Scholar
Pharmacokinetic-pharmacodynamic modelling to investigate in vitro synergy between colistin and fusidic acid against MDR Acinetobacter baumannii
L. Phee, Frank Kloprogge, R. Morris, J. Barrett +2 more
2019Journal of Antimicrobial Chemotherapy6 citations Open access
Semantic Scholar
Optimising intravenous salbutamol in children: a phase 2 study
Sandra Walsh, S. Pan, Yucheng Sheng, Frank Kloprogge +3 more
2022Archives of Disease in Childhood5 citations Open access
Semantic Scholar
Emergence of phenotypic and genotypic antimicrobial resistance in Mycobacterium tuberculosis
Frank Kloprogge, Julio Ortiz Canseco, L. Phee, Z. Sadouki +4 more
2022Scientific Reports5 citations Open access
Semantic Scholar
Implications of drug-induced phenotypical resistance: Is isoniazid radicalizing M. tuberculosis?
R. Hammond, Frank Kloprogge, O. Della Pasqua, S. Gillespie
2022Frontiers in Antibiotics4 citations Open access
Semantic Scholar
Correction to: Clinical Pharmacokinetics and Dose Recommendations for Posaconazole in Infants and Children
S. Boonsathorn, I. Cheng, Frank Kloprogge, C. Alonso +6 more
2018Clinical Pharmacokinetics4 citations Open access
Semantic Scholar
Use of hollow fiber systems to model treatment of infections: A practical guide
J. Raaijmakers, Fernando Sanz-García, Z. Sadouki, D. A. Aguilar-Ayala +9 more
2026iScience3 citations Open access
Semantic Scholar
Ethambutol disposition in humans: challenges and limitations of whole-body physiologically-based pharmacokinetic modelling in early drug development.
Letizia Carrara, P. Magni, D. Teutonico, L. Pasotti +2 more
2020European Journal of Pharmaceutical Sciences3 citations Open access
Semantic Scholar
An automated classification pipeline for tables in pharmacokinetic literature
Victoria C. Smith, Ferran Gonzalez Hernandez, Thanaporn Wattanakul, P. Chotsiri +7 more
2025Scientific Reports2 citations Open access
Semantic Scholar
Can phenotypic data complement our understanding of antimycobacterial effects for drug combinations?
Frank Kloprogge, R. Hammond, A. Copas, S. Gillespie +1 more
2019Journal of Antimicrobial Chemotherapy2 citations Open access
Semantic Scholar
An automated pipeline to generate initial estimates for population Pharmacokinetic base models
Zhong-Hui Huang, Matthew Fidler, Minshi Lan, I. Cheng +2 more
2025Journal of Pharmacokinetics and Pharmacodynamics1 citations Open access
Semantic Scholar
Insights into the Role of Rifampicin Exposure and Clinical Baseline Covariates on the Response to Pulmonary Tuberculosis Treatment
Marie Wijk, P. Denti, K. Gausi, B. Myers +17 more
2025Clinical Infectious Diseases1 citations Open access
Semantic Scholar
The impact of physiological state and environmental stress on bacterial load estimation methodologies for Mycobacterium tuberculosis
Arundhati Maitra, Marie Wijk, H. Margaryan, P. Denti +2 more
2024bioRxiv1 citations Open access
Semantic Scholar
Personalized CZA‐ATM dosing against an XDR E. coli in liver transplant patients; the application of the in vitro hollow fiber system
Z. Sadouki, E. Wey, S. Iype, D. Nasralla +5 more
2024Transplant Infectious Disease1 citations Open access
Semantic Scholar
Exploring a combined biomarker for tuberculosis treatment response: protocol for a prospective observational cohort study
Frank Kloprogge, I. Abubakar, H. Esmail, V. Hack +6 more
2021BMJ Open1 citations Open access
Semantic Scholar
Correction to: An automated pipeline to generate initial estimates for population Pharmacokinetic base models
Zhong-Hui Huang, Matthew Fidler, Minshi Lan, I. Cheng +2 more
2026Journal of Pharmacokinetics and Pharmacodynamics0 citations Open access
Semantic Scholar
Pharmacodynamic interactions among meropenem ciprofloxacin and gentamicin in an in-vitro model
Z. Sadouki, E. Wey, L. Read, M. Bayliss +4 more
2025Scientific Reports0 citations
Semantic Scholar
End-to-End Relation Extraction of Pharmacokinetic Estimates from the Scientific Literature
Ferran Gonzalez Hernandez, Victoria C. Smith, Q. Nguyen, Palang Chotsiri +8 more
2024Workshop on Biomedical Natural Language Processing0 citations Open access
Semantic Scholar
Quinoline synergy and reduced use: a study of pharmacodynamic interactions
Z. Sadouki, E. Wey, T. D. McHugh, Frank Kloprogge
2024bioRxiv0 citations Open access
Semantic Scholar
Understanding emergence of antimycobacterial dose dependent resistance
Frank Kloprogge, J. O. Canseco, L. Phee, Z. Sadouki +4 more
2022bioRxiv0 citations Open access
Semantic Scholar
Title: Understanding emergence of antimycobacterial dose dependent
Frank Kloprogge, J. O. Canseco, L. Phee, Z. Sadouki +4 more
20220 citations
Semantic Scholar
Pharmacokinetic model development for total and free vancomycin in critically ill children
F. González, P. De Cock, E. Dhont, S. Vanhaesebrouck +4 more
20190 citations
Semantic Scholar
End of the Road for Adjunctive Vitamin D Therapy for Pulmonary Tuberculosis?
I. Abubakar, Frank Kloprogge
2017American Journal of Respiratory and Critical Care Medicine0 citations Open access
Semantic Scholar
Which data are necessary to build a WB-PBPK model that accurately predicts exposure in the lung? A case study using Ethambutol for tuberculosis treatment
Letizia Carrara, P. Magni, D. Teutonico, O. Della Pasqua +1 more
20170 citations
Semantic Scholar
Dosing recommendation rationale for fixed-dose combinations in children: a shoot from the hip?
M. Cella, Frank Kloprogge, M. Danhof, O. Della Pasqua
20110 citations
Semantic Scholar
Title : Revising paediatric vancomycin dosing accounting for nephrotoxicity in a 1 pharmacokinetic-pharmacodynamic model 2
Frank Kloprogge, L. Hill, J. Booth, N. Klein +3 more
0 citations
Semantic Scholar

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