Sebum Lee

Most-cited papers

1. ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.

   Haiyan Qiu, Sebum Lee, Yulei Shang, Wen-Yuan Wang +16 more

   2021Journal of Clinical Investigation136 citations Open access

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2. Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease

   Claire E. Le Pichon, William J. Meilandt, Sara L. Dominguez, Hilda Solanoy +25 more

   2017Science Translational Medicine134 citations

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3. Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis

   Sebum Lee, Yulei Shang, Stephanie A. Redmond, A. Urisman +15 more

   2016Neuron86 citations Open access

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4. Modeling ALS and FTD with iPSC-derived Neurons

   Sebum Lee, Eric J. Huang

   2015Brain Research71 citations Open access

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5. ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.

   Haiyan Qiu, Sebum Lee, Yulei Shang, Wen-Yuan Wang +16 more

   2014Journal of Clinical Investigation71 citations Open access

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6. Transcriptional Corepressors HIPK1 and HIPK2 Control Angiogenesis Via TGF-β–TAK1–Dependent Mechanism

   Yulei Shang, Christina N Doan, Thomas D. Arnold, Sebum Lee +3 more

   2013PLoS Biology57 citations Open access

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7. Inhibition of basal activity of c-jun-NH2-terminal kinase (JNK) represses the expression of presenilin-1 by a p53-dependent mechanism.

   Sebum Lee, H. Das

   2008Brain Research23 citations

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8. Transcriptional regulation of the presenilin-1 gene controls gamma-secretase activity.

   Sebum Lee, H. Das

   2010Frontiers in Bioscience11 citations

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9. Mechanisms of Dendrite Degeneration in Amyotrophic Lateral Sclerosis

   Sebum Lee, Yulei Shang, Eric J. Huang

   20160 citations

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