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K. Kirou · SciRah

Researcher profile · Semantic Scholar

K. Kirou

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K. Kirou — researcher profile on SciRah

h-index: 38
Works: 100
Citations: 6,004

Most-cited papers

Activation of the interferon-alpha pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease.
K. Kirou, Christina Lee, Sandhya George, Kyriakos Louca +2 more
2005Arthritis & Rheumatism717 citations
Semantic Scholar
Coordinate overexpression of interferon‐α–induced genes in systemic lupus erythematosus
K. Kirou, Christina Lee, Sandhya George, Kyriakos Louca +9 more
2004391 citations
Semantic Scholar
Functional assay of type I interferon in systemic lupus erythematosus plasma and association with anti-RNA binding protein autoantibodies.
J. Hua, K. Kirou, Christina Lee, M. Crow
2006Arthritis & Rheumatism330 citations
Semantic Scholar
Microarray Analysis of Interferon-regulated Genes in SLE
M. Crow, K. Kirou, J. Wohlgemuth
2003Autoimmunity290 citations
Semantic Scholar
Type I Interferons in Autoimmune Disease.
M. Crow, M. Olferiev, K. Kirou
2019Annual Review of Pathology259 citations
Semantic Scholar
Safety profile and clinical activity of sifalimumab, a fully human anti-interferon α monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study
J. Merrill, D. Wallace, M. Petri, K. Kirou +11 more
2011Annals of the Rheumatic Diseases245 citations
Semantic Scholar
Cutting Edge: Autoimmune Disease Risk Variant of STAT4 Confers Increased Sensitivity to IFN-α in Lupus Patients In Vivo1
Silvia N. Kariuki, K. Kirou, E. MacDermott, L. Barillas-arias +2 more
2009Journal of Immunology222 citations Open access
Semantic Scholar
Plasmacytoid dendritic cells promote systemic sclerosis with a key role for TLR8
Marie Dominique Ah Kioon, C. Tripodo, David Fernandez, K. Kirou +4 more
2018Science Translational Medicine205 citations Open access
Semantic Scholar
Imatinib mesylate (Gleevec) in the treatment of diffuse cutaneous systemic sclerosis: results of a 1-year, phase IIa, single-arm, open-label clinical trial
R. Spiera, J. Gordon, J. N. Mersten, C. Magro +6 more
2011Annals of the Rheumatic Diseases177 citations Open access
Semantic Scholar
Coordinate overexpression of interferon-alpha-induced genes in systemic lupus erythematosus.
K. Kirou, Christina Lee, Sandhya George, Kyriakos Louca +9 more
2004Arthritis & Rheumatism169 citations
Semantic Scholar
Long interspersed nuclear element-1 retroelements are expressed in patients with systemic autoimmune disease and induce type I interferon
C. Mavragani, Irina Sagalovskiy, Qiu Guo, Adrianos Nezos +7 more
2016Arthritis & Rheumatology168 citations Open access
Semantic Scholar
Elevated levels and functional capacity of soluble CD40 ligand in systemic lupus erythematosus sera.
R. Vakkalanka, Caroline J. Woo, K. Kirou, Mary Koshy +2 more
1999Arthritis & Rheumatism167 citations Open access
Semantic Scholar
2017 American College of Rheumatology/American Association of Hip and Knee Surgeons Guideline for the Perioperative Management of Antirheumatic Medication in Patients With Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty
S. Goodman, B. Springer, G. Guyatt, M. Abdel +27 more
2017Journal of Arthroplasty160 citations Open access
Semantic Scholar
Autoimmune Disease Risk Variant of IFIH1 Is Associated with Increased Sensitivity to IFN-α and Serologic Autoimmunity in Lupus Patients
T. Robinson, Silvia N. Kariuki, B. Franek, Marissa Kumabe +13 more
2011Journal of Immunology157 citations Open access
Semantic Scholar
Elevated levels of soluble CD40 ligand (sCD40L) in serum of patients with systemic autoimmune diseases.
A. Goules, A. Tzioufas, M. Manousakis, K. Kirou +2 more
2006Journal of Autoimmunity149 citations
Semantic Scholar
Relationship between the type I interferon signature and the response to rituximab in rheumatoid arthritis patients.
R. Thurlings, M. Boumans, J. Tekstra, J. V. van Roon +10 more
2010Arthritis & Rheumatism136 citations
Semantic Scholar
Interferon-α in systemic lupus erythematosus
M. Crow, K. Kirou
2004Current Opinion in Rheumatology136 citations
Semantic Scholar
Anti-interferon alpha treatment in SLE.
K. Kirou, E. Gkrouzman
2013Clinical Immunology130 citations
Semantic Scholar
Felty’s Syndrome Autoantibodies Bind to Deiminated Histones and Neutrophil Extracellular Chromatin Traps
N. Dwivedi, Jagriti Upadhyay, Indira Neeli, Salar N. Khan +10 more
2011Arthritis & Rheumatism128 citations Open access
Semantic Scholar
Targeting of Type I Interferon in Systemic Autoimmune Diseases
M. Crow, M. Olferiev, K. Kirou
2014Translational Research: The Journal of Laboratory and Clinical Medicine113 citations Open access
Semantic Scholar
2017 American College of Rheumatology/American Association of Hip and Knee Surgeons Guideline for the Perioperative Management of Antirheumatic Medication in Patients With Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty
S. Goodman, B. Springer, G. Guyatt, M. Abdel +27 more
2017Arthritis care & research104 citations Open access
Semantic Scholar
2024 American College of Rheumatology (ACR) Guideline for the Screening, Treatment, and Management of Lupus Nephritis
L. Sammaritano, A. Askanase, B. Bermas, M. Dall'Era +48 more
2025Arthritis & Rheumatology99 citations
Semantic Scholar
2024 American College of Rheumatology (ACR) Guideline for the Screening, Treatment, and Management of Lupus Nephritis
L. Sammaritano, A. Askanase, B. Bermas, M. Dall'Era +48 more
2025Arthritis care & research86 citations
Semantic Scholar
Regulation of CD40 ligand expression in systemic lupus erythematosus
M. Crow, K. Kirou
2001Current Opinion in Rheumatology84 citations
Semantic Scholar
2017 American College of Rheumatology / American Association of Hip and Knee Surgeons Guideline for the Perioperative Management of Antirheumatic Medication in Patients With Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty
S. Goodman, B. Springer, G. Guyatt, M. Abdel +27 more
201782 citations
Semantic Scholar
Interferon-α and angiogenic dysregulation in pregnant lupus patients destined for preeclampsia
D. Andrade, Mimi Kim, Luz P. Blanco, S. A. Karumanchi +9 more
2015Arthritis & Rheumatology79 citations Open access
Semantic Scholar
Cell-bound complement activation products in systemic lupus erythematosus: comparison with anti-double-stranded DNA and standard complement measurements
C. Putterman, R. Furie, R. Ramsey-Goldman, A. Askanase +16 more
2014Lupus Science and Medicine79 citations Open access
Semantic Scholar
Defective regulation of L1 endogenous retroelements in primary Sjogren’s syndrome and systemic lupus erythematosus: Role of methylating enzymes
C. Mavragani, Adrianos Nezos, Irina Sagalovskiy, S. Seshan +2 more
2017Journal of Autoimmunity73 citations Open access
Semantic Scholar
Targeting the RhoA-ROCK Pathway to Reverse T Cell Dysfunction in SLE
C. Rozo, Yurii Chinenov, R. Maharaj, Sanjay Gupta +6 more
2016Annals of the Rheumatic Diseases73 citations Open access
Semantic Scholar
Induction of Fas ligand-mediated apoptosis by interferon-alpha.
K. Kirou, R. Krishna, Vakkalanka Maria, Jason M. Butler +1 more
2000Clinical Immunology65 citations
Semantic Scholar
A surge in anti-dsDNA titer predicts a severe lupus flare within six months
N. Pan, I. Amigues, S. Lyman, Roland Duculan +3 more
2014Lupus61 citations
Semantic Scholar
Chronic activation of pDCs in autoimmunity is linked to dysregulated ER stress and metabolic responses
Vidyanath Chaudhary, Marie Dominique Ah Kioon, S. Hwang, Bikash Mishra +9 more
2022Journal of Experimental Medicine60 citations Open access
Semantic Scholar
What Causes Lupus Flares?
D. Fernández, K. Kirou
2016Current Rheumatology Reports60 citations
Semantic Scholar
Enhanced ROCK Activation in Patients with Systemic Lupus Erythematosus
J. Isgro, Sanjay Gupta, Elzbieta Jacek, Tanya Pavri +5 more
2013Arthritis & Rheumatism57 citations Open access
Semantic Scholar
Feasibility, Validity, and Reliability of the 10-item Patient Reported Outcomes Measurement Information System Global Health Short Form in Outpatients with Systemic Lupus Erythematosus
S. Kasturi, J. Szymonifka, J. Burket, J. Berman +4 more
2018Journal of Rheumatology53 citations Open access
Semantic Scholar
T Cell Proliferation Induced by Autologous Non-T Cells Is a Response to Apoptotic Cells Processed by Dendritic Cells1
A. Chernysheva, K. Kirou, M. Crow
2002Journal of Immunology52 citations Open access
Semantic Scholar
Belimumab or anifrolumab for systemic lupus erythematosus? A risk-benefit assessment
K. Kirou, Maria Dall'Era, C. Aranow, H. Anders
2022Frontiers in Immunology42 citations Open access
Semantic Scholar
Validity and Reliability of Patient Reported Outcomes Measurement Information System Computerized Adaptive Tests in Systemic Lupus Erythematosus
S. Kasturi, J. Szymonifka, J. Burket, J. Berman +4 more
2017Journal of Rheumatology42 citations
Semantic Scholar
Cytokine-mediated regulation of activating and inhibitory Fc gamma receptors in human monocytes.
Yi Liu, Emi Masuda, M. Blank, K. Kirou +3 more
2005Journal of Leukocyte Biology26 citations
Semantic Scholar
Increased Serum Type I Interferon Activity in Organ-Specific Autoimmune Disorders: Clinical, Imaging, and Serological Associations
C. Mavragani, T. Niewold, A. Chatzigeorgiou, S. Danielides +5 more
2013Frontiers in Immunology20 citations Open access
Semantic Scholar
Type I interferon and neutrophil transcripts in lupus nephritis renal biopsies: Clinical and histopathological associations.
C. Mavragani, K. Kirou, S. Seshan, M. Crow
2022Rheumatology18 citations Open access
Semantic Scholar
Feasibility of Patient-Reported Outcomes Measurement Information System (PROMIS®) computerized adaptive tests in systemic lupus erythematosus outpatients
S. Kasturi, J. Burket, J. Berman, K. Kirou +3 more
2018Lupus17 citations
Semantic Scholar
Activation of type I interferon in systemic lupus erythematosus
K. Kirou, C. Mavragani, M. Crow
2007Expert Review of Clinical Immunology17 citations
Semantic Scholar
Novel molecular signatures in mononuclear cell populations from patients with systemic lupus erythematosus.
M. Olferiev, Elzbieta Jacek, K. Kirou, M. Crow
2016Clinical Immunology16 citations
Semantic Scholar
Belimumab in systemic lupus erythematosus: an update for clinicians
Susan S. Kim, K. Kirou, D. Erkan
2012Therapeutic Advances in Chronic Disease15 citations Open access
Semantic Scholar
Evaluation of a Patient-Reported Frailty Tool in Women with Systemic Lupus Erythematosus
Sarah B. Lieber, M. Nahid, S. Paget, J. Berman +7 more
2021Journal of Rheumatology14 citations Open access
Semantic Scholar
Measurement of cytokines in autoimmune disease.
K. Kirou, Christina Lee, M. Crow
2004Methods in Molecular Medicine14 citations Open access
Semantic Scholar
Soluble mediators as therapeutic targets in systemic lupus erythematosus: cytokines, immunoglobulin receptors, and the complement system.
K. Kirou, J. Salmon, M. Crow
2006Rheumatic Disease Clinics of North America13 citations
Semantic Scholar
Remission of juvenile rheumatoid arthritis after infection with parvovirus B19.
H. Bateman, K. Kirou, S. Paget, M. Crow +1 more
1999Journal of Rheumatology13 citations
Semantic Scholar
Anti-neutrophil Cytoplasmic Antibody (c-ANCA) Positive Recurrent Eosinophilic Fasciitis Responsive to Cyclophosphamide
V. Haiduc, D. Erkan, K. Kirou, S. Birchansky +2 more
2008HSS Journal ®10 citations Open access
Semantic Scholar

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