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Y. Kanwar · SciRah

Researcher profile · Semantic Scholar

Y. Kanwar

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Y. Kanwar — researcher profile on SciRah

h-index: 66
Works: 346
Citations: 19K

Most-cited papers

Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis
Ya-Chun Han, Xiao-xuan Xu, Cheng-Yuan Tang, Peng Gao +10 more
2018Redox Biology410 citations Open access
Semantic Scholar
Disruption of renal tubular mitochondrial quality control by Myo-inositol oxygenase in diabetic kidney disease.
Ming Zhan, Irtaza Usman, Lin Sun, Y. Kanwar
2015Journal of the American Society of Nephrology270 citations Open access
Semantic Scholar
INSIGHTS INTO THE MECHANISMS INVOLVED IN THE EXPRESSION AND REGULATION OF EXTRACELLULAR MATRIX PROTEINS IN DIABETIC NEPHROPATHY
Chun Hu, Lin Sun, Li Xiao, Ya-Chun Han +7 more
2015Current Medicinal Chemistry185 citations Open access
Semantic Scholar
Myo-inositol oxygenase expression profile modulates pathogenic ferroptosis in the renal proximal tubule.
F. Deng, I. Sharma, Ying-Bo Dai, Ming Yang +1 more
2019Journal of Clinical Investigation179 citations Open access
Semantic Scholar
Type I interferon causes thrombotic microangiopathy by a dose-dependent toxic effect on the microvasculature.
D. Kavanagh, Sarah L. McGlasson, A. Jury, Jac Williams +19 more
2016Blood107 citations Open access
Semantic Scholar
RELEVANCE OF TNF-α IN THE CONTEXT OF OTHER INFLAMMATORY CYTOKINES IN THE PROGRESSION OF DIABETIC NEPHROPATHY
Lin Sun, Y. Kanwar
2015Kidney International99 citations Open access
Semantic Scholar
DsbA-L ameliorates high glucose induced tubular damage through maintaining MAM integrity
Ming Yang, Li Zhao, Peng Gao, Xue-Jing Zhu +12 more
2019EBioMedicine83 citations Open access
Semantic Scholar
Disulfide-bond A oxidoreductase-like protein protects against ectopic fat deposition and lipid-related kidney damage in diabetic nephropathy.
Xianghui Chen, Ya-Chun Han, Peng Gao, Ming Yang +12 more
2019Kidney International81 citations Open access
Semantic Scholar
PPARα-Deficient ob/ob Obese Mice Become More Obese and Manifest Severe Hepatic Steatosis Due to Decreased Fatty Acid Oxidation.
Qian Gao, Yuzhi Jia, Gong-She Yang, Xiaohong Zhang +7 more
2015American Journal of Pathology73 citations Open access
Semantic Scholar
miR-93 regulates Msk2-mediated chromatin remodelling in diabetic nephropathy
Shawn S. Badal, Yin Wang, J. Long, D. Corcoran +5 more
2016Nature Communications66 citations Open access
Semantic Scholar
MicroRNA-129-5p modulates epithelial-to-mesenchymal transition by targeting SIP1 and SOX4 during peritoneal dialysis
Li Xiao, Xun Zhou, Fu-You Liu, Chun Hu +7 more
2015Laboratory Investigation61 citations Open access
Semantic Scholar
Non-Chimeric HLA-Identical Renal Transplant Tolerance: Regulatory Immunophenotypic/Genomic Biomarkers
Joseph R. Leventhal, James M. Mathew, D. Salomon, S. Kurian +10 more
2015American Journal of Transplantation58 citations Open access
Semantic Scholar
Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc
Shi-Kun Yang, Li Zhao, Ya-Chun Han, Yu Liu +10 more
2017Redox Biology57 citations Open access
Semantic Scholar
Angiotensin converting enzyme 2 amplification limited to the circulation does not protect mice from development of diabetic nephropathy
J. Wysocki, M. Ye, A. Khattab, A. Fogo +5 more
2016Kidney International55 citations Open access
Semantic Scholar
New Pandemic: Obesity and Associated Nephropathy
Isha Sharma, Y. Liao, Xiaoping Zheng, Y. Kanwar
2021Frontiers in Medicine50 citations Open access
Semantic Scholar
Beneficial Effects of Myo-Inositol Oxygenase Deficiency in Cisplatin-Induced AKI.
R. Dutta, V. Kondeti, I. Sharma, N. Chandel +2 more
2017Journal of the American Society of Nephrology50 citations Open access
Semantic Scholar
Activation of endothelial NAD(P)H oxidase accelerates early glomerular injury in diabetic mice
H. Nagasu, M. Satoh, E. Kiyokage, K. Kidokoro +5 more
2015Laboratory Investigation49 citations Open access
Semantic Scholar
Perturbations in mitochondrial dynamics by p66Shc lead to renal tubular oxidative injury in human diabetic nephropathy.
Ming Zhan, Irtaza Usman, Jingbo Yu, Lie-Min Ruan +5 more
2018Clinical science46 citations
Semantic Scholar
p66Shc: A novel biomarker of tubular oxidative injury in patients with diabetic nephropathy
Xiao-xuan Xu, Xue-Jing Zhu, Mingming Ma, Ya-Chun Han +7 more
2016Scientific Reports43 citations Open access
Semantic Scholar
Myo-inositol Oxygenase (MIOX) Overexpression Drives the Progression of Renal Tubulointerstitial Injury in Diabetes
Ada Admin, I. Sharma, F. Deng, Yingjun Liao +1 more
2020Diabetes42 citations Open access
Semantic Scholar
Contribution of myo-inositol oxygenase in AGE:RAGE-mediated renal tubulointerstitial injury in the context of diabetic nephropathy.
I. Sharma, R. Tupe, Aryana K Wallner, Y. Kanwar
2018AJP - Renal Physiology42 citations Open access
Semantic Scholar
Prolylcarboxypeptidase deficiency is associated with increased blood pressure, glomerular lesions, and cardiac dysfunction independent of altered circulating and cardiac angiotensin II
C. Maier, I. Schadock, Philipp K. Haber, J. Wysocki +9 more
2017Journal of molecular medicine39 citations
Semantic Scholar
Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice
Yuzhi Jia, Hsiang-Chun Chang, M. Schipma, Jing Liu +11 more
2016PLoS ONE37 citations Open access
Semantic Scholar
Regulated cell death in cisplatin-induced AKI: Relevance of myo-inositol metabolism.
F. Deng, Xiaoping Zheng, I. Sharma, Ying-Bo Dai +2 more
2021AJP - Renal Physiology36 citations Open access
Semantic Scholar
Modulation of gentamicin-induced acute kidney injury by myo-inositol oxygenase via the ROS/ALOX-12/12-HETE/GPR31 signaling pathway
Isha Sharma, Yingjun Liao, Xiaoping Zheng, Y. Kanwar
2022JCI Insight34 citations Open access
Semantic Scholar
High Glucose-Induced Hypomethylation Promotes Binding of Sp-1 to Myo-Inositol Oxygenase: Implication in the Pathobiology of Diabetic Tubulopathy.
I. Sharma, R. Dutta, Neelottma Singh, Y. Kanwar
2017American Journal of Pathology34 citations Open access
Semantic Scholar
myo-Inositol Oxygenase Overexpression Accentuates Generation of Reactive Oxygen Species and Exacerbates Cellular Injury following High Glucose Ambience
Lin Sun, R. Dutta, P. Xie, Y. Kanwar
2016Journal of Biological Chemistry33 citations Open access
Semantic Scholar
A Novel Soluble ACE2 Protein Provides Lung and Kidney Protection in Mice Susceptible to Lethal SARS-CoV-2 Infection
Luise Hassler, J. Wysocki, I. Gelarden, Isha Sharma +12 more
2022Journal of the American Society of Nephrology32 citations Open access
Semantic Scholar
AKT regulation of mesothelial-to-mesenchymal transition in peritoneal dialysis is modulated by smurf2 and deubiquitinating enzyme USP4
Li Xiao, Xiang-Ping Peng, Fu-You Liu, Cheng-Yuan Tang +9 more
2015BMC Cell Biology30 citations Open access
Semantic Scholar
A clinically relevant murine model unmasks a “two‐hit” mechanism for reactivation and dissemination of cytomegalovirus after kidney transplant
Z. Zhang, Longhui Qiu, Shi-Xian Yan, Jiao-Jing Wang +10 more
2019American Journal of Transplantation29 citations Open access
Semantic Scholar
Kidney-intrinsic factors determine the severity of ischemia/reperfusion injury in a mouse model of delayed graft function
Longhui Qiu, Xing-Qiang Lai, Jiao-Jing Wang, X. Yeap +11 more
2020Kidney International27 citations Open access
Semantic Scholar
IRE1α-mediated monounsaturated fatty acid synthesis drives B cell differentiation and lupus-like autoimmune disease
Yana Zhang, Ming Gui, Yajun Wang, N. Mani +9 more
2021Arthritis & Rheumatology23 citations Open access
Semantic Scholar
Effects of Omega-3 Fatty Acids on Markers of Inflammation in Patients with Chronic Kidney Disease: A Controversial Issue
Chun Hu, Ming Yang, Xue-Jing Zhu, Peng Gao +8 more
2017Therapeutic apheresis and dialysis22 citations Open access
Semantic Scholar
The Association between Symptoms of Depression and Anxiety, Quality of Life, and Diabetic Kidney Disease among Chinese Adults: A Cross-Sectional Study
Yan Shen, Yi Chen, Shichun Huang, Xu-Ying Yao +2 more
2022International Journal of Environmental Research and Public Health21 citations Open access
Semantic Scholar
Transcriptional and Translational Modulation of myo-Inositol Oxygenase (Miox) by Fatty Acids
T. Tominaga, R. Dutta, Darukeshwara Joladarashi, T. Doi +2 more
2015Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Myo-inositol oxygenase overexpression exacerbates cadmium-induced kidney injury via oxidant stress and necroptosis.
Xiaoping Zheng, F. Deng, Isha Sharma, Y. Kanwar
2022AJP - Renal Physiology20 citations Open access
Semantic Scholar
The transcription factor ChREBP links mitochondrial lipidomes to mitochondrial morphology and progression of diabetic kidney disease
Li Li, J. Long, K. Mise, Naravat Poungavrin +7 more
2023Journal of Biological Chemistry19 citations Open access
Semantic Scholar
An adjustment in BMP4 function represents a treatment for diabetic nephropathy and podocyte injury
Y. Fujita, T. Tominaga, H. Abe, Yumi Kangawa +9 more
2018Scientific Reports19 citations Open access
Semantic Scholar
Recipient Myd88 Deficiency Promotes Spontaneous Resolution of Kidney Allograft Rejection.
N. Lerret, Ting Li, Jiao-Jing Wang, Hee-Kap Kang +7 more
2015Journal of the American Society of Nephrology19 citations Open access
Semantic Scholar
Role for carbohydrate response element-binding protein (ChREBP) in high glucose-mediated repression of long noncoding RNA Tug1
J. Long, Daniel L. Galvan, K. Mise, Y. Kanwar +5 more
2020Journal of Biological Chemistry18 citations Open access
Semantic Scholar
NON-PURINE SELECTIVE XANTHINE OXIDASE INHIBITOR AMELIORATES GLOMERULAR ENDOTHELIAL INJURY IN InsAkita DIABETIC MICE.
S. Itano, Hiroyuki Kadoya, M. Satoh, Takashi Nakamura +4 more
2020AJP - Renal Physiology18 citations Open access
Semantic Scholar
CHIP protects against septic acute kidney injury by inhibiting NLRP3-mediated pyroptosis
Hao Zhang, Ze-Kun Deng, Yi-Long Wang, Xiaoping Zheng +6 more
2023iScience17 citations Open access
Semantic Scholar
A possible mechanism of hyperlipidemia in a patient with metastatic non-small cell lung cancer on lorlatinib therapy
Katherine McGee, N. Stone, S. Wadhwani, Y. Kanwar +2 more
2021Journal of Oncology Pharmacy Practice17 citations
Semantic Scholar
Myo-Inositol Supplementation Alleviates Cisplatin-Induced Acute Kidney Injury via Inhibition of Ferroptosis
Hui-Yue Qi, F. Deng, Yinghuai Wang, Hao Zhang +2 more
2022Cells16 citations Open access
Semantic Scholar
Myo-inositol oxygenase accentuates renal tubular injury initiated by endoplasmic reticulum stress.
T. Tominaga, I. Sharma, Y. Fujita, T. Doi +2 more
2019AJP - Renal Physiology14 citations Open access
Semantic Scholar
Glomerular mesangial cell recruitment and function require the co-receptor neuropilin-1.
Christina S. Bartlett, Rizaldy P. Scott, Isabel A Carota, M. Wnuk +3 more
2017AJP - Renal Physiology14 citations Open access
Semantic Scholar
Aging and Diabetic Kidney Disease: Emerging Pathogenetic Mechanisms and Clinical Implications.
Yi Chen, Y. Kanwar, Xueqin Chen, Ming Zhan
2023Current Medicinal Chemistry13 citations
Semantic Scholar
PIMT/NCOA6IP Deletion in the Mouse Heart Causes Delayed Cardiomyopathy Attributable to Perturbation in Energy Metabolism
Yuzhi Jia, Ning Liu, N. Viswakarma, Ruya Sun +6 more
2018International Journal of Molecular Sciences12 citations Open access
Semantic Scholar
PRMT4 interacts with NCOA4 to inhibit ferritinophagy in cisplatin‐induced acute kidney injury
Li-Zhi Zhou, Ze-Kun Deng, Yi-Long Wang, Hao Zhang +5 more
2024The FASEB Journal11 citations Open access
Semantic Scholar
Murine cytomegalovirus dissemination but not reactivation in donor-positive/recipient-negative allogeneic kidney transplantation can be effectively prevented by transplant immune tolerance.
Anil Dangi, Shuangjin Yu, Frances T. Lee, M. Burnette +6 more
2020Kidney International10 citations Open access
Semantic Scholar

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