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Hsiang-Chun Chang · SciRah

Researcher profile · Semantic Scholar

Hsiang-Chun Chang

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Hsiang-Chun Chang — researcher profile on SciRah

h-index: 21
Works: 65
Citations: 1,572

Most-cited papers

mTOR Regulates Cellular Iron Homeostasis through Tristetraprolin
Marina Bayeva, Arineh Khechaduri, S. Puig, Hsiang-Chun Chang +3 more
2012Cell Metabolism187 citations Open access
Semantic Scholar
Hexokinase 1 cellular localization regulates the metabolic fate of glucose
Adam De Jesus, F. Keyhani-Nejad, Carolina M Pusec, L. Goodman +17 more
2022Molecules and Cells147 citations Open access
Semantic Scholar
Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2
Xiao-Yan Yang, S. Park, Hsiang-Chun Chang, J. Shapiro +11 more
2017Journal of Clinical Investigation138 citations Open access
Semantic Scholar
Reduction in mitochondrial iron alleviates cardiac damage during injury
Hsiang-Chun Chang, Rong-Xue Wu, Meng Shang, Tatsuya Sato +7 more
2016EMBO Molecular Medicine125 citations Open access
Semantic Scholar
Role of Heme in Cardiovascular Physiology and Disease
K. Sawicki, Hsiang-Chun Chang, H. Ardehali
2015Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease86 citations Open access
Semantic Scholar
mRNA-binding protein tristetraprolin is essential for cardiac response to iron deficiency by regulating mitochondrial function
Tatsuya Sato, Hsiang-Chun Chang, Marina Bayeva, J. Shapiro +14 more
2018Proceedings of the National Academy of Sciences of the United States of America79 citations Open access
Semantic Scholar
Heme Levels are Increased in Human Failing Hearts
Arineh Khechaduri, Marina Bayeva, Hsiang-Chun Chang, H. Ardehali
2013Journal of the American College of Cardiology75 citations Open access
Semantic Scholar
Hexokinase 1 Cellular Localization Regulates the Metabolic Fate of Glucose
Adam De Jesus, Carolina M Pusec, F. Keyhani-Nejad, L. Goodman +17 more
2021Social Science Research Network73 citations Open access
Semantic Scholar
RNA helicase DDX5 is a p53-independent target of ARF that participates in ribosome biogenesis
A. Saporita, Hsiang-Chun Chang, C. Winkeler, A. Apicelli +5 more
2011Cancer Research71 citations Open access
Semantic Scholar
Aging is associated with increased brain iron through cortex-derived hepcidin expression
Tatsuya Sato, J. Shapiro, Hsiang-Chun Chang, Richard A. Miller +1 more
2021bioRxiv64 citations Open access
Semantic Scholar
Short Communication: High Cellular Iron Levels Are Associated with Increased HIV Infection and Replication
Hsiang-Chun Chang, Marina Bayeva, Babafemi O. Taiwo, F. Palella +2 more
2015AIDS Research and Human Retroviruses58 citations Open access
Semantic Scholar
Increased Heme Levels in the Heart Lead to Exacerbated Ischemic Injury
K. Sawicki, Meng Shang, Rong-Xue Wu, Hsiang-Chun Chang +6 more
2015Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease54 citations Open access
Semantic Scholar
Snf1-related kinase improves cardiac mitochondrial efficiency and decreases mitochondrial uncoupling
A. Rines, Hsiang-Chun Chang, Rong-Xue Wu, Tatsuya Sato +13 more
2017Nature Communications52 citations Open access
Semantic Scholar
Cardiac-specific ablation of ARNT leads to lipotoxicity and cardiomyopathy.
Rong-Xue Wu, Hsiang-Chun Chang, Arineh Khechaduri, Kusum Chawla +9 more
2014Journal of Clinical Investigation39 citations Open access
Semantic Scholar
When less is more: novel mechanisms of iron conservation
Marina Bayeva, Hsiang-Chun Chang, Rong-Xue Wu, H. Ardehali
2013Trends in endocrinology and metabolism38 citations Open access
Semantic Scholar
Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice
Yuzhi Jia, Hsiang-Chun Chang, M. Schipma, Jing Liu +11 more
2016PLoS ONE37 citations Open access
Semantic Scholar
Iron Drives Anabolic Metabolism Through Active Histone Demethylation and mTORC1
J. Shapiro, Hsiang-Chun Chang, Yuki Tatekoshi, Zi-Bo Zhao +24 more
2023Nature Cell Biology35 citations Open access
Semantic Scholar
Hepatic tristetraprolin promotes insulin resistance through RNA destabilization of FGF21.
K. Sawicki, Hsiang-Chun Chang, J. Shapiro, Marina Bayeva +5 more
2018JCI Insight34 citations Open access
Semantic Scholar
Getting to the “Heart” of Cardiac Disease by Decreasing Mitochondrial Iron
Hsiang-Chun Chang, J. Shapiro, H. Ardehali
2016Circulation Research32 citations Open access
Semantic Scholar
Corrigendum: Snf1-related kinase improves cardiac mitochondrial efficiency and decreases mitochondrial uncoupling
A. Rines, Hsiang-Chun Chang, Rong-Xue Wu, Tatsuya Sato +13 more
2017Nature Communications25 citations Open access
Semantic Scholar
SIRT2 inhibition protects against cardiac hypertrophy and ischemic injury
Xiaoyan Yang, Hsiang-Chun Chang, Yuki Tatekoshi, A. Mahmoodzadeh +7 more
2023eLife24 citations Open access
Semantic Scholar
ZFP36L2 suppresses mTORc1 through a P53-dependent pathway to prevent peripartum cardiomyopathy in mice
H. Kouzu, Y. Tatekoshi, Hsiang-Chun Chang, J. Shapiro +8 more
2022Journal of Clinical Investigation18 citations Open access
Semantic Scholar
Augmenter of Liver Regeneration Regulates Cellular Iron Homeostasis by Modulating Mitochondrial Transport of ATP-Binding Cassette B8
Hsiang-Chun Chang, J. Shapiro, Xing-Hang Jiang, Grant Senyei +3 more
2020bioRxiv17 citations Open access
Semantic Scholar
Intravenous iron therapy in heart failure: a different perspective
K. Ghafourian, Hsiang-Chun Chang, H. Ardehali
2019European Journal of Heart Failure13 citations Open access
Semantic Scholar
DNA damage and nuclear morphological changes in cardiac hypertrophy are mediated by SNRK through actin depolymerization
Paulina J. Stanczyk, Y. Tatekoshi, J. Shapiro, K. Nayudu +8 more
2023Circulation9 citations Open access
Semantic Scholar
DNA damage and nuclear morphological changes in cardiac hypertrophy are mediated by SNRK through actin depolymerization
Paulina J. Stanczyk, Yuki Tatekoshi, J. Shapiro, K. Nayudu +8 more
2023bioRxiv8 citations Open access
Semantic Scholar
Dual inhibition of both the EGFR and erbB2 effectively inhibits promotion of skin tumors during two-stage carcinogenesis
K. Kiguchi, T. Kitamura, Tricia Moore, M. Rumi +5 more
2010Cancer Prevention Research8 citations Open access
Semantic Scholar
The good neighbor: Coping with insulin resistance by modulating adipose tissue endothelial cell function
S. Yar, Hsiang-Chun Chang, H. Ardehali
2016Circulation Research7 citations Open access
Semantic Scholar
Iron and Sex Cross Paths in the Heart
J. Shapiro, Hsiang-Chun Chang, H. Ardehali
2017Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease6 citations Open access
Semantic Scholar
Human induced pluripotent stem cell-derived cardiomyocytes to study inflammation-induced aberrant calcium transient
Yuki Tatekoshi, Chun-Lei Chen, J. Shapiro, Hsiang-Chun Chang +7 more
2024bioRxiv5 citations Open access
Semantic Scholar
SIRT2 inhibition protects against cardiac hypertrophy and heart failure
Xiaoyan Yang, Hsiang-Chun Chang, Yuki Tatekoshi, Maryam Balibegloo +5 more
2023bioRxiv3 citations Open access
Semantic Scholar
Metabolic Suppression of HIF-1α Contributes to Susceptibility of Ischemic Injury in Diabetic Hearts∗
Adam De Jesus, Hsiang-Chun Chang, H. Ardehali
2018JACC: Basic to Translational Science2 citations Open access
Semantic Scholar
Correction: Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice
Yu Jia, Hsiang-Chun Chang, M. Schipma, Jing Liu +11 more
2016PLoS ONE2 citations Open access
Semantic Scholar
Optimized protocol for quantification of mitochondrial non-heme and heme iron content in mouse tissues and cultured cells
Tatsuya Sato, Hsiang-Chun Chang, K. Sawicki, H. Ardehali
2023STAR Protocols1 citations Open access
Semantic Scholar
Augmenter of liver regeneration regulates cellular iron homeostasis by modulating mitochondrial transport of ATP-binding cassette B8
Hsiang-Chun Chang, J. Shapiro, Xing-Hang Jiang, Grant Senyei +4 more
2021eLife1 citations Open access
Semantic Scholar
Abstract 263: Loss of the RNA-binding Protein ZFP36L2 Results in Peri-partum Cardiomyopathy Through Dysregulation of the P53-mTOR Pathway
Yuki Tatekoshi, H. Kouzu, J. Shapiro, Hsiang-Chun Chang +5 more
2020Circulation Research1 citations
Semantic Scholar
Abstract 12876: Post-Transcriptional Regulation of Cardiac Fatty Acid Metabolism by the Tandem Zinc Finger Mrna Binding Protein Tristetraprolin
Mohammad Keykhaei, Hsiang-Chun Chang, Tatsuya Sato, K. Sawicki +3 more
2022Circulation0 citations
Semantic Scholar
The Jumonji-C Histone Lysine Demethylase KDM3B Senses Cellular Iron to Regulate Anabolism Through mTORC1
J. Shapiro, Hsiang-Chun Chang, Zi-Bo Zhao, Justin A. Geier +22 more
2021Social Science Research Network0 citations
Semantic Scholar
Author response: Aging is associated with increased brain iron through cortex-derived hepcidin expression
Tatsuya Sato, J. Shapiro, Hsiang-Chun Chang, Richard A. Miller +1 more
20210 citations Open access
Semantic Scholar
Author response: Augmenter of liver regeneration regulates cellular iron homeostasis by modulating mitochondrial transport of ATP-binding cassette B8
Hsiang-Chun Chang, J. Shapiro, Xing-Hang Jiang, Grant Senyei +4 more
20210 citations Open access
Semantic Scholar
Abstract 14395: Abnormal Regulation of P53-mTOR Pathway by MRNA-binding Protein ZFP36L2 in Peri-partum Cardiomyopathy
Yuki Tatekoshi, H. Kouzu, Hsiang-Chun Chang, J. Shapiro +5 more
2020Circulation0 citations
Semantic Scholar
Abstract 424: Loss of Sirt2 Protects Against Pressure Overload- and Ischemic Reperfusion Injury-induced Cardiac Dysfunction
Teruki Sato, Xiao-Yan Yan, Hsiang-Chun Chang, Chun-Lei Chen +2 more
2020Circulation Research0 citations
Semantic Scholar
Abstract 308: Role of Snf1-related Kinase as a Regulator of Chromatin Modifications and Dna-damage Response in Heart Injury
P. Stanczyk, Zachary Zilber, Adam De Jesus, Hsiang-Chun Chang +1 more
2019Circulation Research0 citations
Semantic Scholar
Abstract 12423: The Tandem Zinc Finger mRNA Binding Protein, Tristetraprolin (TTP), is a Novel Regulator of Cardiac Branched Chain Amino Acid (BCAA) Catabolism
Hsiang-Chun Chang, S. Yar, H. Kouzu, Chun-Lei Chen +2 more
20180 citations
Semantic Scholar
Abstract 17382: Jumonji-C Histone Demethylases Are Cellular Iron Sensors That Control mTORC1 and Mitophagy
J. Shapiro, Hsiang-Chun Chang, H. Ardehali
2018Circulation0 citations
Semantic Scholar
Abstract 14457: mRNA Binding Protein ZFP36L2 Regulates Cardiac DNA Damage Response Through Regulation of p53 and Helicase
H. Kouzu, Hsiang-Chun Chang, J. Shapiro, Adam Dejesus +3 more
20170 citations
Semantic Scholar
Abstract 19291: Iron Deprivation Inhibits mTOR Activity by Regulating Amino Acid Homeostasis
J. Shapiro, Hsiang-Chun Chang, Tatsuya Sato, K. Sawicki +5 more
20170 citations
Semantic Scholar
Abstract 20358: The mRNA Binding Protein Zfp36l1 Regulates Cardiac Development Genes and is Essential for Cardiac Function in Adulthood
Adam De Jesus, J. Shaprio, Hsiang-Chun Chang, Shan Meng +3 more
20170 citations
Semantic Scholar
Abstract 12522: Downregulation of Aryl-hydrocarbon Receptor Nuclear Translocator (ARNT) Exacerbates Cardiac Insulin Resistance After High Fat Diet
Hsiang-Chun Chang, Tatsuya Sato, Rong-Xue Wu, Meng Shang +2 more
2016Circulation0 citations
Semantic Scholar
Abstract 12526: Snf1-related Kinase Improves Cardiac Mitochondrial Efficiency by Decreasing Mitochondrial Uncoupling
A. Rines, Hsiang-Chun Chang, Rong-Xue Wu, Tatsuya Sato +11 more
2016Circulation0 citations
Semantic Scholar

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