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J. Boucher · SciRah

Researcher profile · Semantic Scholar

J. Boucher

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J. Boucher — researcher profile on SciRah

h-index: 7
Works: 20
Citations: 325

Most-cited papers

Quantifying and understanding the fitness effects of protein mutations: Laboratory versus nature
J. Boucher, D. Bolon, Dan S. Tawfik
2016Protein Science93 citations Open access
Semantic Scholar
An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases
J. Boucher, Joseph R. Jacobowitz, B. Beckett, S. Classen +1 more
2014eLife80 citations Open access
Semantic Scholar
CRISPR-Cas9–mediated saturated mutagenesis screen predicts clinical drug resistance with improved accuracy
Le-Yuan Ma, J. Boucher, J. Paulsen, Sebastian Matuszewski +12 more
2017Proceedings of the National Academy of Sciences of the United States of America55 citations Open access
Semantic Scholar
Viewing Protein Fitness Landscapes Through a Next-Gen Lens
J. Boucher, Pamela Cote, J. Flynn, Li Jiang +4 more
2014Genetics55 citations Open access
Semantic Scholar
Functional and Structural Resilience of the Active Site Loop in the Evolution of Plasmodium Lactate Dehydrogenase
J. Wirth, J. Boucher, Joseph R. Jacobowitz, S. Classen +1 more
2018bioRxiv19 citations Open access
Semantic Scholar
Constrained mutational sampling of amino acids in HIV-1 protease evolution
J. Boucher, T. Whitfield, Ann Dauphin, G. Nachum +6 more
2018bioRxiv13 citations Open access
Semantic Scholar
Quantitative measurement of epidermal growth factor receptor-mitogen-activated protein kinase signal transduction using a nine-plex, peptide-based immunoassay.
Christine Rauh‐Adelmann, John Moskow, James R. Graham, Lucy G. Yen +5 more
2008Analytical Biochemistry7 citations
Semantic Scholar
Quantifying and understanding the fitness effects of protein mutations: Laboratory versus nature
J. Boucher, D. Bolon, Dan S. Tawfik
2019Protein Science2 citations Open access
Semantic Scholar
Mutational scan of self-cleavage by HIV-1 protease provides new views of a conformationally dynamic mechanism
G. Nachum, J. Boucher, Julia Flynn, Princess Quansah +2 more
2026Journal of Virology1 citations Open access
Semantic Scholar
Mutational scan of self-cleavage by HIV-1 protease provides new views of a conformationally dynamic mechanism
G. Nachum, J. Boucher, Julia Flynn, Princess Quansah +2 more
2025bioRxiv1 citations Open access
Semantic Scholar
In vivo Gene Writing with engineered retrotransposons.
Dong-Hui Li, Alberto De Iaco, Kevin C. Ngan, Georgy Smyshlyaev +38 more
2026Cell0 citations Open access
Semantic Scholar
Strong epistasis constrains the evolution of strict substrate specificity in apicomplexan lactate dehydrogenases
J. Wirth, J. Boucher, Chang-Ai Xu, S. Classen +1 more
2023bioRxiv0 citations Open access
Semantic Scholar
SciFest VI , Aug 4 , 2016 Investigating Active Site Dynamics of Apicomplexans Malate Dehydrogenase by Nuclear Magnetic Resonance
Miriam R. Hood, J. Wirth, Michelle Y Fry, J. Boucher +5 more
20160 citations
Semantic Scholar
Investigating Active Site Dynamics of Apicomplexans Malate Dehydrogenase by Nuclear Magnetic Resonance
Miriam R. Hood, J. Wirth, Michelle Y Fry, J. Boucher +3 more
20160 citations
Semantic Scholar
Come to Cobalt : Synthesis and Characterization of Novel Cobalt-SNS Complexes for H 2 Fuel Catalysis
Miriam R. Hood, J. Wirth, Michelle Y Fry, J. Boucher +5 more
20160 citations
Semantic Scholar
Author response: An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases
J. Boucher, Joseph R. Jacobowitz, B. Beckett, S. Classen +1 more
20140 citations Open access
Semantic Scholar
Crystal structure of Plasmodium falciparum lactate dehydrogenase mutant W107fA.
J. Boucher, Joseph R. Jacobowitz, B. Beckett, S. Classen +1 more
20140 citations
Semantic Scholar
Evolution of apicomplexan lactate dehydrogenases by saltation and neofunctionalization
J. Boucher
20140 citations
Semantic Scholar
Crystal structure of ancestral apicomplexan malate dehydrogenase with lactate.
J. Boucher, J. R. Jacobowitz, B. Beckett, S. Classen +1 more
20140 citations
Semantic Scholar
Replacement Matrices for Transmembrane Proteins
J. Boucher, Adam C. B. Drake, M. Gallegos, N. Lazar +2 more
20110 citations
Semantic Scholar
P81-T Antibody Arrays for Measuring Site-Specific Protein Phosphorylation
Christine Rauh‐Adelmann, N. Gordon, James R. Graham, Cheryl E. Murphy +3 more
20070 citations
Semantic Scholar

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