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T. A. Hill · SciRah

Researcher profile · Semantic Scholar

T. A. Hill

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T. A. Hill — researcher profile on SciRah

h-index: 27
Works: 62
Citations: 2,766

Most-cited papers

Constraining cyclic peptides to mimic protein structure motifs.
T. A. Hill, N. Shepherd, F. Diness, D. Fairlie
2014Angewandte Chemie304 citations
Semantic Scholar
Systemic delivery of peptides by the oral route: Formulation and medicinal chemistry approaches.
David J Brayden, T. A. Hill, D. Fairlie, S. Maher +1 more
2020Advanced Drug Delivery Reviews223 citations Open access
Semantic Scholar
Inhibition of dynamin mediated endocytosis by the dynoles--synthesis and functional activity of a family of indoles.
T. A. Hill, C. Gordon, A. McGeachie, Barbara Venn-Brown +8 more
2009Journal of Medicinal Chemistry172 citations Open access
Semantic Scholar
A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells.
J. Stehn, N. Haass, Teresa T. Bonello, Melissa Desouza +19 more
2013Cancer Research163 citations
Semantic Scholar
Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency
Rosemary S. Harrison, N. Shepherd, H. N. Hoang, Gloria Ruiz-Gómez +6 more
2010Proceedings of the National Academy of Sciences of the United States of America162 citations Open access
Semantic Scholar
Comparative α-helicity of cyclic pentapeptides in water.
A. D. de Araujo, H. N. Hoang, Mei W. Kok, Frederik Diness +6 more
2014Angewandte Chemie148 citations
Semantic Scholar
Improving on nature: making a cyclic heptapeptide orally bioavailable.
D. Nielsen, H. N. Hoang, R. Lohman, T. A. Hill +9 more
2014Angewandte Chemie126 citations
Semantic Scholar
Update 1 of: Beta-strand mimetics.
W. A. Loughlin, J. Tyndall, M. Glenn, T. A. Hill +1 more
2010Chemical Reviews112 citations
Semantic Scholar
Heterocyclic substituted cantharidin and norcantharidin analogues--synthesis, protein phosphatase (1 and 2A) inhibition, and anti-cancer activity.
T. A. Hill, Scott G. Stewart, Benjamin Sauer, J. Gilbert +3 more
2007Bioorganic & Medicinal Chemistry Letters102 citations
Semantic Scholar
Norcantharimides, synthesis and anticancer activity: Synthesis of new norcantharidin analogues and their anticancer evaluation.
T. A. Hill, Scott G. Stewart, S. Ackland, J. Gilbert +3 more
2007Bioorganic & Medicinal Chemistry87 citations
Semantic Scholar
Crystal Structures of Protein-Bound Cyclic Peptides.
A. Malde, T. A. Hill, A. Iyer, D. Fairlie
2019Chemical Reviews85 citations Open access
Semantic Scholar
Small molecule inhibitors of dynamin I GTPase activity: development of dimeric tyrphostins.
T. A. Hill, L. Odell, J. K. Edwards, M. Graham +7 more
2005Journal of Medicinal Chemistry79 citations Open access
Semantic Scholar
Long chain amines and long chain ammonium salts as novel inhibitors of dynamin GTPase activity.
T. A. Hill, L. Odell, Annie Quan, R. Abagyan +3 more
2004Bioorganic & Medicinal Chemistry Letters72 citations Open access
Semantic Scholar
Green chemistry approaches to the Knoevenagel condensation: comparison of ethanol, water and solvent free (dry grind) approaches
A. McCluskey, P. Robinson, T. A. Hill, Janet L. Scott +1 more
200267 citations
Semantic Scholar
Norcantharidin Analogues: Synthesis, Anticancer Activity and Protein Phosphatase 1 and 2A Inhibition
T. A. Hill, Scott G. Stewart, C. Gordon, S. Ackland +4 more
2008ChemMedChem65 citations
Semantic Scholar
Iminochromene inhibitors of dynamins I and II GTPase activity and endocytosis.
T. A. Hill, A. Mariana, C. Gordon, L. Odell +7 more
2010Journal of Medicinal Chemistry64 citations Open access
Semantic Scholar
Constraining Cyclic Peptides to Mimic Protein Structure Motifs
T. A. Hill, N. Shepherd, F. Diness, D. Fairlie
201560 citations
Semantic Scholar
Truncated and Helix-Constrained Peptides with High Affinity and Specificity for the cFos Coiled-Coil of AP-1
T. Rao, Gloria Ruiz-Gómez, T. A. Hill, H. N. Hoang +2 more
2013PLoS ONE59 citations Open access
Semantic Scholar
Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed.
T. A. Hill, R. Lohman, H. N. Hoang, D. Nielsen +17 more
2014ACS Medicinal Chemistry Letters56 citations Open access
Semantic Scholar
Connecting hydrophobic surfaces in cyclic peptides increases membrane permeability.
H. N. Hoang, T. A. Hill, D. Fairlie
2020Angewandte Chemie53 citations
Semantic Scholar
Short Hydrophobic Peptides with Cyclic Constraints Are Potent Glucagon-like Peptide-1 Receptor (GLP-1R) Agonists.
H. N. Hoang, K. Song, T. A. Hill, D. R. Derksen +15 more
2015Journal of Medicinal Chemistry47 citations Open access
Semantic Scholar
Helix Nucleation by the Smallest Known α-Helix in Water.
H. N. Hoang, Russell W. Driver, Renée L. Beyer, T. A. Hill +6 more
2016Angewandte Chemie39 citations Open access
Semantic Scholar
Hydrogen-induced fast fracture in notched 1500 and 1700 MPa class automotive martensitic advanced high-strength steel
J. Venezuela, T. A. Hill, Qing-Jun Zhou, Huixing Li +6 more
202136 citations
Semantic Scholar
Novel helix-constrained nociceptin derivatives are potent agonists and antagonists of ERK phosphorylation and thermal analgesia in mice.
Rosemary S. Harrison, Gloria Ruiz-Gómez, T. A. Hill, Shiao Y. Chow +5 more
2010Journal of Medicinal Chemistry36 citations Open access
Semantic Scholar
Synthesis and biological evaluation of norcantharidin analogues: towards PP1 selectivity.
Scott G. Stewart, T. A. Hill, J. Gilbert, S. Ackland +2 more
2007Bioorganic & Medicinal Chemistry36 citations
Semantic Scholar
Pyrimidyn compounds: dual-action small molecule pyrimidine-based dynamin inhibitors.
A. McGeachie, L. Odell, Annie Quan, James A. Daniel +17 more
2013ACS Chemical Biology34 citations
Semantic Scholar
BiCl3-mediated opening of epoxides, a facile route to chlorohydrins or amino alcohols : one reagent, two paths
A. McCluskey, Sarah K. Leitch, James R Garner, Christine E. Caden +3 more
200528 citations
Semantic Scholar
Downsizing Proto-oncogene cFos to Short Helix-Constrained Peptides That Bind Jun.
Daniel Baxter, S. R. Perry, T. A. Hill, Mei W. Kok +4 more
2017ACS Chemical Biology27 citations Open access
Semantic Scholar
De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex
Kai-En Chen, Qian Guo, T. A. Hill, Yi Cui +19 more
2020bioRxiv26 citations Open access
Semantic Scholar
Contiguous hydrophobic and charged surface patches in short helix-constrained peptides drive cell permeability.
S. R. Perry, T. A. Hill, A. D. de Araujo, H. N. Hoang +1 more
2018Organic and biomolecular chemistry26 citations Open access
Semantic Scholar
Pyrimidine-Based Inhibitors of Dynamin I GTPase Activity: Competitive Inhibition at the Pleckstrin Homology Domain.
L. Odell, Mohammed K. Abdel-Hamid, T. A. Hill, N. Chau +7 more
2017Journal of Medicinal Chemistry23 citations Open access
Semantic Scholar
Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signaling.
F. Plisson, T. A. Hill, J. Mitchell, H. N. Hoang +11 more
2017European journal of medicinal chemistry23 citations Open access
Semantic Scholar
The antiplasmodial activity of norcantharidin analogs.
Joanna Bajsa, A. McCluskey, C. Gordon, Scott G. Stewart +4 more
2010Bioorganic & Medicinal Chemistry Letters22 citations
Semantic Scholar
An Ugi-intramolecular Diels–Alder route to highly substituted tetrahydroepoxyisoindole carboxamides
C. Gordon, K. Young, M. Robertson, T. A. Hill +1 more
201118 citations
Semantic Scholar
A novel long-range n to π* interaction secures the smallest known α-helix in water.
H. N. Hoang, Chong-Yang Wu, T. A. Hill, A. D. de Araujo +3 more
2019Angewandte Chemie17 citations Open access
Semantic Scholar
Structure-Activity Relationships of Wollamide Cyclic Hexapeptides with Activity against Drug-Resistant and Intracellular Mycobacterium tuberculosis
Zeinab G. Khalil, T. A. Hill, L. M. De Leon Rodriguez, R. Lohman +7 more
2019Antimicrobial Agents and Chemotherapy13 citations Open access
Semantic Scholar
Folding pentapeptides into left and right handed alpha helices
H. N. Hoang, G. Abbenante, T. A. Hill, Gloria Ruiz-Gómez +1 more
201210 citations
Semantic Scholar
Helix-constrained nociceptin peptides are potent agonists and antagonists of ORL-1 and nociception.
R. Lohman, Rosemary S. Harrison, Gloria Ruiz-Gómez, H. N. Hoang +5 more
2015Vitamins and hormones8 citations
Semantic Scholar
Modifying a Hydroxyl Patch in Glucagon-like Peptide 1 Produces Biased Agonists with Unique Signaling Profiles.
Peiqi Wang, T. A. Hill, J. Mitchell, R. Fitzsimmons +6 more
2022Journal of Medicinal Chemistry7 citations Open access
Semantic Scholar
Correction: Twists or turns: stabilising alpha vs. beta turns in tetrapeptides
H. N. Hoang, T. A. Hill, Gloria Ruiz-Gómez, F. Diness +5 more
2020Chemical Science6 citations Open access
Semantic Scholar
Mirror image pairs of cyclic hexapeptides have different oral bioavailabilities and metabolic stabilities.
T. A. Hill, David P. Fairlie, R. Lohman, H. N. Hoang +2 more
2019Chemical Communications6 citations
Semantic Scholar
Helical cyclic pentapeptides constrain HIV-1 Rev peptide for enhanced RNA binding
Rosemary S. Harrison, N. Shepherd, H. N. Hoang, Renée L. Beyer +6 more
20145 citations
Semantic Scholar
Wollamide Cyclic Hexapeptides Synergize with Established and New Tuberculosis Antibiotics in Targeting Mycobacterium tuberculosis
Rachel F Rollo, G. Mori, T. A. Hill, D. Hillemann +4 more
2023Microbiology spectrum4 citations Open access
Semantic Scholar
Helical structure in cyclic peptides: effect of N-methyl amides versus esters.
Chong-Yang Wu, H. N. Hoang, T. A. Hill, Jun-Xian Lim +4 more
2022Chemical Communications4 citations
Semantic Scholar
Alpha helix nucleation by a simple cyclic tetrapeptide
H. N. Hoang, Chong-Yang Wu, Renée L. Beyer, T. A. Hill +1 more
20164 citations
Semantic Scholar
Parallel solution-phase synthesis of targeted tyrphostin libraries with anticancer activity
T. A. Hill, J. Sakoff, P. Robinson, A. McCluskey
20054 citations
Semantic Scholar
High Cell Permeability Does Not Predict Oral Bioavailability for Analogues of Cyclic Heptapeptide Sanguinamide A
D. Nielsen, R. Lohman, H. N. Hoang, D. Fairlie +1 more
20202 citations
Semantic Scholar
Identification of Aminopyrimidine Regioisomers via Line Broadening Effects in 1H and 13C NMR Spectroscopy
James R Garner, T. A. Hill, L. Odell, P. Keller +2 more
20042 citations
Semantic Scholar
Inhibiting, stabilising and probing the function of the Retromer endosomal trafficking complex through the novel macrocyclic peptides
Kai-En Chen, Qian Guo, T. A. Hill, Yi Cui +9 more
2021Acta Crystallographica Section A: Foundations and Advances0 citations Open access
Semantic Scholar
CHARACTERIZING PEPTIDE ALPHA HELICES VIA COLD ION SPECTROSCOPY OF MODEL COMPOUNDS
John T. Lawler, T. Zwier, S. McLuckey, D. Fairlie +2 more
2018Proceedings of the 73rd International Symposium on Molecular Spectroscopy0 citations Open access
Semantic Scholar

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H. N. Hoang×21
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