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M. Ruigrok · SciRah

Researcher profile · Semantic Scholar

M. Ruigrok

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M. Ruigrok — researcher profile on SciRah

h-index: 11
Works: 27
Citations: 428

Most-cited papers

Emerging Insights for Translational Pharmacokinetic and Pharmacokinetic-Pharmacodynamic Studies: Towards Prediction of Nose-to-Brain Transport in Humans
M. Ruigrok, E. D. de Lange
2015AAPS Journal107 citations Open access
Semantic Scholar
Diphtheria toxoid and N-trimethyl chitosan layer-by-layer coated pH-sensitive microneedles induce potent immune responses upon dermal vaccination in mice.
P. Schipper, K. van der Maaden, Vincent Groeneveld, M. Ruigrok +6 more
2017Journal of Controlled Release67 citations Open access
Semantic Scholar
Pulmonary administration of small interfering RNA: The route to go?
M. Ruigrok, H. Frijlink, W. Hinrichs
2016Journal of Controlled Release45 citations Open access
Semantic Scholar
Gene therapy strategies for idiopathic pulmonary fibrosis: recent advances, current challenges, and future directions
M. Ruigrok, H. Frijlink, B. Melgert, P. Olinga +1 more
2021Molecular Therapy: Methods & Clinical Development39 citations Open access
Semantic Scholar
Are inhaled mRNA vaccines safe and effective? A review of preclinical studies
Evalyne M Jansen, H. Frijlink, W. Hinrichs, M. Ruigrok
2022Expert Opinion on Drug Delivery34 citations Open access
Semantic Scholar
siRNA‐mediated protein knockdown in precision‐cut lung slices
M. Ruigrok, J. Xian, H. Frijlink, B. Melgert +2 more
2018European journal of pharmaceutics and biopharmaceutics29 citations Open access
Semantic Scholar
siRNA-Mediated RNA Interference in Precision-Cut Tissue Slices Prepared from Mouse Lung and Kidney
M. Ruigrok, Nalinie Maggan, Delphine Willaert, H. Frijlink +3 more
2017AAPS Journal25 citations Open access
Semantic Scholar
The effects of oxygen concentration on cell death, anti-oxidant transcription, acute inflammation, and cell proliferation in precision-cut lung slices
M. Ruigrok, J. Tomar, H. Frijlink, B. Melgert +2 more
2019Scientific Reports23 citations Open access
Semantic Scholar
Shifting Paradigms for Suppressing Fibrosis in Kidney Transplants: Supplementing Perfusion Solutions With Anti-fibrotic Drugs
L. V. van Leeuwen, H. Leuvenink, P. Olinga, M. Ruigrok
2022Frontiers in Medicine15 citations Open access
Semantic Scholar
Silencing Heat Shock Protein 47 (HSP47) in Fibrogenic Precision-Cut Lung Slices: A Surprising Lack of Effects on Fibrogenesis?
M. Ruigrok, Khaled E. M. El Amasi, D. Leeming, J. Sand +3 more
2021Frontiers in Medicine14 citations Open access
Semantic Scholar
Nanoparticulate Impurities Isolated from Pharmaceutical-Grade Sucrose Are a Potential Threat to Protein Stability
D. Weinbuch, M. Ruigrok, W. Jiskoot, A. Hawe
2017Pharmaceutical Research12 citations
Semantic Scholar
Osteoprotegerin is an Early Marker of the Fibrotic Process and of Antifibrotic Treatment Responses in Ex Vivo Lung Fibrosis
K. S. S. Putri, A. Adhyatmika, C. Boorsma, H. Habibie +7 more
2024Lung9 citations Open access
Semantic Scholar
Freeze-Drying in Sucrose Followed by Cryomilling Enables the Formulation of sa-mRNA–LNP Powders for Inhalation
E. M. Jansen, M. Ruigrok, M. Suh, P. M. Ruppel +5 more
2026Pharmaceutics3 citations Open access
Semantic Scholar
Role of RANKL in Alveolar Epithelial Cell Regeneration: Potential Novel Contributor to Lung Tissue Repair
H. Habibie, Shanshan Song, C. Boorsma, K. S. S. Putri +12 more
2023bioRxiv3 citations Open access
Semantic Scholar
Slice of Life: Porcine Kidney Slices for Testing Antifibrotic Drugs in a Transplant Setting
L. V. van Leeuwen, M. Ruigrok, H. Leuvenink, P. Olinga
2023Transplantology2 citations Open access
Semantic Scholar
RANKL confers protection against cell death in precision-cut lung slices
M. Ruigrok, M. Roest, H. Frijlink, P. Olinga +2 more
2022Frontiers in Physiology2 citations Open access
Semantic Scholar
siRNA-Mediated RNA Interference in Precision-Cut Tissue Slices Prepared from Mouse Lung and Kidney
M. Ruigrok, Nalinie Maggan, Delphine Willaert, H. Frijlink +3 more
2017AAPS Journal1 citations Open access
Semantic Scholar
Modelling Acid-Induced Lung Damage in Precision-Cut Lung Slices: An Ex Vivo Animal Model
Carmen A. Moes, C. T. Gan, L. Venema, R. F. Hoffmann +4 more
2023Transplantology0 citations Open access
Semantic Scholar
211.5: Targeted delivery of galunisertib using machine perfusion reduces fibrogenesis in an integrated ex vivo renal transplant and fibrogenesis model.
L. V. van Leeuwen, M. Ruigrok, C. Jaynes, Benedikt M. Kessler +2 more
2023Transplantation0 citations Open access
Semantic Scholar
315.3: Targeted Delivery of Galunisertib Attenuates Fibrogenesis in an Integrated Ex Vivo Renal Transplant and Fibrosis Model
L. V. van Leeuwen, H. Leuvenink, Benedikt M. Kessler, P. Olinga +1 more
2022Transplantation0 citations Open access
Semantic Scholar
Targeted delivery of galunisertib attenuates fibrogenesis in an integrated ex vivo renal transplant and fibrosis model
L. V. van Leeuwen, H. Leuvenink, B. Kessler, P. Olinga +1 more
2022bioRxiv0 citations Open access
Semantic Scholar
TREATING CIRCULATORY DEATH DONOR KIDNEYS WITH ANTI-FIBROTIC DRUGS USING EX VIVO PRECISION CUT KIDNEY SLICES
L. V. van Leeuwen, M. Ruigrok, P. Olinga, H. Leuvenink
20200 citations Open access
Semantic Scholar
Knockdown of heat shock protein 47 (HSP47) and its effects on fibrogenesis
M. Ruigrok, K. El-Amasi, H. Frijlink, W. Hinrichs +1 more
20200 citations
Semantic Scholar
siRNA in precision-cut lung slices: knocking down fibrosis?
M. Ruigrok
20190 citations Open access
Semantic Scholar
PRECISION-CUT LUNG SLICES IN FIBROSIS RESEARCH
M. Ruigrok
20190 citations
Semantic Scholar
University of Groningen siRNA-mediated RNA interference in precision-cut tissue slices prepared from mouse lung and kidney Ruigrok,
Mitchel J. R. Maggan, Nalinie Willaert, Delphine Frijlink, Henderik W. Melgert +10 more
20170 citations
Semantic Scholar
Emerging Insights for Translational Pharmacokinetic and Pharmacokinetic-Pharmacodynamic Studies: Towards Prediction of Nose-to-Brain Transport in Humans
M. Ruigrok, E. D. de Lange
2015AAPS Journal0 citations Open access
Semantic Scholar

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