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D. Newton · SciRah

Researcher profile · Semantic Scholar

D. Newton

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D. Newton — researcher profile on SciRah

h-index: 26
Works: 71
Citations: 2,385

Most-cited papers

The second to fourth digit ratio and variation in the androgen receptor gene
J. Manning, P. Bundred, D. Newton, B. Flanagan
2003365 citations
Semantic Scholar
Immunogenetics shows that not all MBL are equal: the larger the clone, the more similar to CLL.
A. Vardi, Antonis Dagklis, L. Scarfò, D. Jelinek +15 more
2013Blood200 citations Open access
Semantic Scholar
Evidence that tissue resident human enthesis γδT-cells can produce IL-17A independently of IL-23R transcript expression
R. Cuthbert, C. Bridgewood, A. Watad, E. Fragkakis +8 more
2019Annals of the Rheumatic Diseases141 citations Open access
Semantic Scholar
Minimal residual disease is an independent predictor for 10-year survival in CLL.
M. Kwok, A. Rawstron, A. Varghese, P. Evans +5 more
2016Blood129 citations Open access
Semantic Scholar
Intraepithelial γδ+ Lymphocytes Maintain the Integrity of Intestinal Epithelial Tight Junctions in Response to Infection
Jane E. Dalton, S. Cruickshank, Charlotte E. Egan, Rainy Mears +10 more
2006128 citations
Semantic Scholar
In Vitro Generation of Long-lived Human Plasma Cells
Mario Cocco, Sophie Stephenson, M. Care, D. Newton +6 more
2012Journal of Immunology97 citations
Semantic Scholar
Th2 IL-4/IL-13 dual blockade with Dupilumab is linked to some Emergent Th17 type Diseases including seronegative arthritis, enthesitis/enthesopathy, but not humoral autoimmune diseases.
C. Bridgewood, M. Wittmann, T. Macleod, A. Watad +7 more
2022Journal of Investigative Dermatology94 citations Open access
Semantic Scholar
Toll-like receptor-mediated responses of primary intestinal epithelial cells during the development of colitis.
Joy Singh, S. Cruickshank, D. Newton, Louise Wakenshaw +5 more
2005American Journal of Physiology - Gastrointestinal and Liver Physiology93 citations Open access
Semantic Scholar
MCP-1 but not CINC synthesis is increased in rat pancreatic acini in response to cerulein hyperstimulation.
M. Bhatia, M. Brady, Y. Kang, Eithne Costello +4 more
2002American Journal of Physiology - Gastrointestinal and Liver Physiology74 citations
Semantic Scholar
Normal human enthesis harbours conventional CD4+ and CD8+ T cells with regulatory features and inducible IL-17A and TNF expression
A. Watad, Hannah Rowe, Tobias Russell, Qiao Zhou +17 more
2020Annals of the Rheumatic Diseases73 citations Open access
Semantic Scholar
Intraepithelial gammadelta+ lymphocytes maintain the integrity of intestinal epithelial tight junctions in response to infection.
Jane E. Dalton, S. Cruickshank, Charlotte E. Egan, Rainy Mears +10 more
2006Gastroenterology71 citations
Semantic Scholar
Intestinal Intraepithelial Lymphocyte-Enterocyte Crosstalk Regulates Production of Bactericidal Angiogenin 4 by Paneth Cells upon Microbial Challenge
Catherine Walker, I. Hautefort, Jane E. Dalton, K. Overweg +6 more
2013PLoS ONE64 citations Open access
Semantic Scholar
The incidence and prevalence of patients with paroxysmal nocturnal haemoglobinuria and aplastic anaemia PNH syndrome: A retrospective analysis of the UK’s population‐based haematological malignancy research network 2004‐2018
S. Richards, D. Painter, A. J. Dickinson, M. Griffin +13 more
2021European Journal of Haematology61 citations Open access
Semantic Scholar
A subset of IL‐10‐producing γδ T cells protect the liver from Listeria‐elicited, CD8+ T cell‐mediated injury
Katherine A. Rhodes, E. Andrew, D. Newton, D. Tramonti +1 more
2008European Journal of Immunology60 citations Open access
Semantic Scholar
Evidence for the involvement of lung-specific γδ T cell subsets in local responses to Streptococcus pneumoniae infection
A. Kirby, D. Newton, S. Carding, P. Kaye
2007European Journal of Immunology56 citations Open access
Semantic Scholar
Early emergence of CD19-negative human antibody secreting cells at the plasmablast to plasma cell transition
G. Arumugakani, S. Stephenson, D. Newton, A. Rawstron +4 more
2017Journal of Immunology47 citations Open access
Semantic Scholar
Unexpected connections of the IL-23/IL-17 and IL-4/IL-13 cytokine axes in inflammatory arthritis and enthesitis.
C. Bridgewood, D. Newton, Nicola Luigi Bragazzi, M. Wittmann +1 more
2021Seminars in Immunology46 citations
Semantic Scholar
Exploratory Study of MYD88 L265P, Rare NLRP3 Variants, and Clonal Hematopoiesis Prevalence in Patients With Schnitzler Syndrome
S. Pathak, D. Rowczenio, R. Owen, G. Doody +8 more
2019Arthritis & Rheumatology45 citations
Semantic Scholar
Delineation of the Function of a Major γδ T Cell Subset during Infection1
E. Andrew, D. Newton, Jane E. Dalton, Charlotte E. Egan +4 more
2005Journal of Immunology43 citations Open access
Semantic Scholar
Neoadjuvant Intravenous Oncolytic Vaccinia Virus Therapy Promotes Anticancer Immunity in Patients
Adel Samson, E. West, J. Carmichael, K. Scott +26 more
2022Cancer immunology research41 citations Open access
Semantic Scholar
The prothrombotic state in paroxysmal nocturnal hemoglobinuria: a multifaceted source
Barnaby Peacock-Young, F. Macrae, D. Newton, A. Hill +1 more
2017Haematologica41 citations Open access
Semantic Scholar
T Helper 2 IL-4/IL-13 Dual Blockade with Dupilumab Is Linked to Some Emergent T Helper 17 ‒ Type Diseases, Including Seronegative Arthritis and Enthesitis/ Enthesopathy, but Not to Humoral Autoimmune Diseases
C. Bridgewood, M. Wittmann, T. Macleod, A. Watad +7 more
39 citations
Semantic Scholar
Characterization of Blood Mucosal‐Associated Invariant T Cells in Patients With Axial Spondyloarthritis and of Resident Mucosal‐Associated Invariant T Cells From the Axial Entheses of Non‐Axial Spondyloarthritis Control Patients
N. Rosine, Hannah Rowe, S. Koturan, Hanane Yahia-Cherbal +13 more
2022Arthritis & Rheumatology32 citations Open access
Semantic Scholar
Evidence for the opposing roles of different γδ T cell subsets in macrophage homeostasis
D. Tramonti, E. Andrew, K. Rhodes, D. Newton +1 more
200632 citations
Semantic Scholar
Extravascular Hemolysis Due to C3-Loading in Patients with PNH Treated with Eculizumab: Defining the Clinical Syndrome
C. McKinley, S. Richards, T. Munir, M. Griffin +7 more
201728 citations
Semantic Scholar
Conserved structure and tissue expression of rat eotaxin
C. Williams, D. Newton, S. A. Wilson, T. Williams +2 more
1997Immunogenetics26 citations
Semantic Scholar
Effectiveness of SARS-CoV-2 vaccination in patients with rheumatoid arthritis (RA) on DMARDs: as determined by antibody and T cell responses
B. Saleem, R. Ross, L. Bissell, A. Aslam +19 more
2022RMD Open25 citations Open access
Semantic Scholar
Presentation clinical, haematological and immunophenotypic features of 1081 patients with GPI‐deficient (paroxysmal nocturnal haemoglobinuria) cells detected by flow cytometry
S. Richards, A. J. Dickinson, M. Cullen, M. Griffin +7 more
2020British Journal of Haematology23 citations Open access
Semantic Scholar
The CXCR6/CXCL16 axis links inflamm-aging to disease severity in COVID-19 patients
D. Payne, S. Dalal, Richard M. Leach, R. Parker +12 more
2021bioRxiv19 citations Open access
Semantic Scholar
Natural Killer Cell Receptor Expression by Human First Trimester Decidual Granular Leukocytes and T‐Lymphocytes
Barry J. Lewis, S. Croker, D. Newton, G. P. Lennon +2 more
2002American Journal of Reproductive Immunology18 citations
Semantic Scholar
Evidence for the opposing roles of different gamma delta T cell subsets in macrophage homeostasis.
D. Tramonti, E. Andrew, K. Rhodes, D. Newton +1 more
2006European Journal of Immunology17 citations
Semantic Scholar
Identification of Novel γδ T-Cell Subsets following Bacterial Infection in the Absence of Vγ1+ T Cells: Homeostatic Control of γδ T-Cell Responses to Pathogen Infection by Vγ1+ T Cells
D. Newton, E. Andrew, Jane E. Dalton, Rainy Mears +1 more
2006Infection and Immunity16 citations Open access
Semantic Scholar
Monoclonal B-cell lymphocytosis in a hospital-based UK population and a rural Ugandan population: a cross-sectional study
A. Rawstron, Aloysius Ssemaganda, R. de Tute, Chi Doughty +10 more
2017The Lancet Haematology15 citations Open access
Semantic Scholar
A novel isoform of human membrane cofactor protein (CD46) mRNA generated by intron retention.
A. Pollard, Brian F. Flanagan, D. Newton, Peter M. Johnson
1998Gene14 citations
Semantic Scholar
Evidence of B Cell Clonality and Investigation Into Properties of the IgM in Patients With Schnitzler Syndrome
S. Pathak, D. Rowczenio, S. Lara-Reyna, M. Kačar +7 more
2020Frontiers in Immunology12 citations Open access
Semantic Scholar
Patients with paroxysmal nocturnal hemoglobinuria demonstrate a prothrombotic clotting phenotype which is improved by complement inhibition with eculizumab
F. Macrae, Barnaby Peacock-Young, P. Bowman, S. Baker +11 more
2020American journal of hematology/oncology12 citations Open access
Semantic Scholar
“Red Cell Complement Loading In PNH Patients On Eculizumab Is Associated With a C3 Polymorphism Which Influences C3 Function, Predicts For Increased Extravascular Hemolysis and Provides a Rationale For C3 Inhibition.”
P. Kaudlay, H. Hua, Guan-Yi He, D. Newton +6 more
201312 citations
Semantic Scholar
Identification of novel gammadelta T-cell subsets following bacterial infection in the absence of Vgamma1+ T cells: homeostatic control of gammadelta T-cell responses to pathogen infection by Vgamma1+ T cells.
D. Newton, E. Andrew, Jane E. Dalton, Rainy Mears +1 more
2006Infection and Immunity9 citations
Semantic Scholar
An ultra-deep sequencing strategy to detect sub-clonal TP53 mutations in presentation chronic lymphocytic leukaemia cases using multiple polymerases
L. Worrillow, P. Baskaran, M. Care, A. Varghese +8 more
2016Oncogene8 citations
Semantic Scholar
Human Decidualized Endometrial T Lymphocytes Do Not Substantially Down‐Regulate CD3ζ
I. Bedenicki, D. Newton, B. Flanagan, P. Johnson +2 more
1999American Journal of Reproductive Immunology8 citations
Semantic Scholar
TNFB gene polymorphism in insulin-dependent diabetes mellitus: association with HLA-DR alleles.
D. Newton, D. Bowen-Jones, I. Crosby, R. M. Barnes +1 more
1998European journal of immunogenetics7 citations
Semantic Scholar
COVID-19 vaccination antibody responses in patients with aplastic anaemia and paroxysmal nocturnal haemoglobinuria
A. Pike, C. McKinley, Briony Forrest, Rebecca Scott +19 more
2022The Lancet Haematology6 citations Open access
Semantic Scholar
Assessment of Eculizumab and C5 Levels in PNH Treatment: Molar Ratio of Eculizumab to C5 Level Effectively Predicts Ongoing Dosage Changes in a Cohort of 50 Patients Treated with Eculizumab
D. Newton, C. McKinley, A. Ricardo, Hoarty Michelle Denise +7 more
20176 citations
Semantic Scholar
Delineation of the Function of a Major
P. Scott, S. Carding, Charlotte E. Egan, S. J. Goodwin +4 more
20136 citations
Semantic Scholar
Highly selective SYK inhibitor, GSK143, abrogates survival signals in chronic lymphocytic leukaemia
A. Varghese, A. Rawstron, D. Newton, R. Tooze +4 more
2018British Journal of Haematology4 citations Open access
Semantic Scholar
Molecular Mechanisms of Ibrutinib Resistance: Defining a Logical Approach to Improving Targeted Therapy in CLL
S. Farag, D. Newton, G. Doody, L. Mahmoud +3 more
20164 citations
Semantic Scholar
Independent prognostic significance of minimal residual disease status in chronic lymphocytic leukaemia
M. Kwok, A. Rawstron, A. Varghese, P. Evans +5 more
20144 citations Open access
Semantic Scholar
Response to: ‘Beware of wolves in sheep's clothing: immune cell plasticity and instability in health and disease’ by Alunno et al
A. Watad, Hannah Rowe, D. Newton, C. Bridgewood +1 more
2020Annals of the Rheumatic Diseases3 citations Open access
Semantic Scholar
Mycoplasma origin of tumor cell protein
Brian F. Flanagan, D. Newton, P. Johnson
1998Nature Medicine3 citations
Semantic Scholar
Immunophenotypic assessment of PNH clones in major and minor cell lineages in the peripheral blood of patients with paroxysmal nocturnal hemoglobinuria
S. Richards, A. J. Dickinson, D. Newton, P. Hillmen
2022Cytometry. Part B, Clinical cytometry2 citations
Semantic Scholar

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