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Kuang-Hung Cheng · SciRah

Researcher profile · Semantic Scholar

Kuang-Hung Cheng

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Kuang-Hung Cheng — researcher profile on SciRah

h-index: 28
Works: 62
Citations: 5,336

Most-cited papers

Histone Deacetylases: Unique Players in Shaping the Epigenetic Histone Code
S. Thiagalingam, Kuang-Hung Cheng, H. Lee, Nora D Mineva +2 more
2003Annals of the New York Academy of Sciences729 citations
Semantic Scholar
Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.
N. Bardeesy, Kuang-Hung Cheng, Justin H. Berger, Gerald C. Chu +7 more
2006Genes & Development694 citations Open access
Semantic Scholar
Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse.
N. Bardeesy, Andrew J. Aguirre, Gerald C. Chu, Kuang-Hung Cheng +10 more
2006Proceedings of the National Academy of Sciences of the United States of America607 citations
Semantic Scholar
Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder.
H. Abdolmaleky, Kuang-Hung Cheng, S. Faraone, M. Wilcox +12 more
2006Human Molecular Genetics466 citations Open access
Semantic Scholar
Hypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: A preliminary report
H. Abdolmaleky, Kuang-Hung Cheng, Andrea L. Russo, Cassandra L. Smith +8 more
2005American Journal of Medical Genetics Part B: Neuropsychiatric Genetics399 citations
Semantic Scholar
Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy
Shannon M. McAuliffe, Stefanie L. Morgan, G. Wyant, L. T. Tran +16 more
2012Proceedings of the National Academy of Sciences of the United States of America329 citations Open access
Semantic Scholar
Pten constrains centroacinar cell expansion and malignant transformation in the pancreas.
B. Stanger, Bangyan L. Stiles, G. Lauwers, N. Bardeesy +10 more
2005Cancer Cell319 citations Open access
Semantic Scholar
Smad4 inactivation promotes malignancy and drug resistance of colon cancer
P. Papageorgis, Kuang-Hung Cheng, Sait Ozturk, Yi-Fen Gong +4 more
2011Cancer Research211 citations Open access
Semantic Scholar
Differential DNA Hypermethylation of Critical Genes Mediates the Stage-Specific Tobacco Smoke-Induced Neoplastic Progression of Lung Cancer
Andrea L. Russo, Arunthathi Thiagalingam, H. Pan, J. Califano +6 more
2005Clinical Cancer Research151 citations Open access
Semantic Scholar
Loss of heterozygosity as a predictor to map tumor suppressor genes in cancer: molecular basis of its occurrence
S. Thiagalingam, R. L. Foy, Kuang-Hung Cheng, H. Lee +2 more
2002Current Opinion in Oncology120 citations
Semantic Scholar
Stem Cell Marker Nestin Is Critical for TGF-β1-Mediated Tumor Progression in Pancreatic Cancer
Huei-Ting Su, Ching-Chieh Weng, Pi-Jung Hsiao, Li-hua Chen +4 more
2013Molecular Cancer Research87 citations Open access
Semantic Scholar
The Activation of MEK/ERK Signaling Pathway by Bone Morphogenetic Protein 4 to Increase Hepatocellular Carcinoma Cell Proliferation and Migration
Chiang-Yen Chiu, K. Kuo, Tzu-Lei Kuo, King-teh Lee +1 more
2012Molecular Cancer Research74 citations
Semantic Scholar
RECK Inhibits Stemness Gene Expression and Tumorigenicity of Gastric Cancer Cells by Suppressing ADAM‐Mediated Notch1 Activation
Kun-Jing Hong, Deng-Chyang Wu, Kuang-Hung Cheng, Li-Tzong Chen +1 more
2014Journal of Cellular Physiology70 citations
Semantic Scholar
Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvironment
Ya-Ting Wang, Jocelyn Chen, Chou-Wei Chang, J. Jen +13 more
2017Journal of Clinical Investigation68 citations Open access
Semantic Scholar
SMAD4 Loss triggers the phenotypic changes of pancreatic ductal adenocarcinoma cells
Yu-Wen Chen, Pi-Jung Hsiao, Ching-Chieh Weng, K. Kuo +4 more
2014BMC Cancer67 citations Open access
Semantic Scholar
Loss of heterozygosity patterns provide fingerprints for genetic heterogeneity in multistep cancer progression of tobacco smoke-induced non-small cell lung cancer.
H. Pan, J. Califano, Jose F. Ponte, Andrea L. Russo +5 more
2005Cancer Research62 citations Open access
Semantic Scholar
Activation of VCAM-1 and Its Associated Molecule CD44 Leads to Increased Malignant Potential of Breast Cancer Cells
Pei Wang, Ching-Chieh Weng, You-Syuan Hou, Shu‐Fang Jian +3 more
2014International Journal of Molecular Sciences56 citations Open access
Semantic Scholar
Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently prevents skin carcinogenesis by suppressing the PKD1-dependent signaling pathway in CD34+ skin stem cells and skin tumors.
Yi-shiou Chiou, S. Sang, Kuang-Hung Cheng, Chi-Tang Ho +2 more
2013Carcinogenesis56 citations
Semantic Scholar
Human adipose-derived stem cells: Isolation, characterization and current application in regeneration medicine
Kuang-Hung Cheng, Tzu-Lei Kuo, K. Kuo, Chang-Chun Hsiao
201156 citations Open access
Semantic Scholar
Mutant Kras-induced upregulation of CD24 enhances prostate cancer stemness and bone metastasis
Ching-Chieh Weng, Peikai Ding, Yu-Hsuan Liu, J. Hawse +6 more
2018Oncogene50 citations Open access
Semantic Scholar
Upregulation of hepatoma-derived growth factor is involved in murine hepatic fibrogenesis.
Y. Kao, Chao-Long Chen, B. Jawan, Yueh‐Hua Chung +11 more
2010Journal of Hepatology46 citations
Semantic Scholar
Elucidation of Epigenetic Inactivation of SMAD8 in Cancer Using Targeted Expressed Gene Display
Kuang-Hung Cheng, Jose F. Ponte, S. Thiagalingam
2004Cancer Research40 citations
Semantic Scholar
CD44 Promotes Lung Cancer Cell Metastasis through ERK–ZEB1 Signaling
Yen-Yun Wang, Anupama Vadhan, Ping-Ho Chen, Yen-Lung Lee +5 more
2021Cancers38 citations Open access
Semantic Scholar
β-catenin-activated autocrine PDGF/Src signaling is a therapeutic target in pancreatic cancer
Tzu-Lei Kuo, Kuang-Hung Cheng, Y. Shan, Li-Tzong Chen +1 more
2019Theranostics34 citations Open access
Semantic Scholar
Loss of the transcriptional repressor TGIF1 results in enhanced Kras-driven development of pancreatic cancer
Ching-Chieh Weng, Mei-Jen Hsieh, Chia-Chen Wu, Yu-Chun Lin +4 more
2019Molecular Cancer32 citations Open access
Semantic Scholar
KRAS mutation coupled with p53 loss is sufficient to induce ovarian carcinosarcomas in mice
Feng-Hsiang Tang, Tsung-Hua Hsieh, Chia-Yi Hsu, Hsiao-Yun Lin +3 more
2017International Journal of Cancer31 citations
Semantic Scholar
Epigenetic inactivation of transforming growth factor‐β1 target gene HEYL, a novel tumor suppressor, is involved in the P53‐induced apoptotic pathway in hepatocellular carcinoma
K. Kuo, Shu‐Fang Jian, YiJing Li, Shi-Wei Wan +4 more
2015Hepatology Research29 citations
Semantic Scholar
Vorinostat decrease M2 macrophage polarization through ARID1A6488delG/HDAC6/IL-10 signaling pathway in endometriosis-associated ovarian carcinoma.
Tsung-Hua Hsieh, Chia-Yi Hsu, Chia-Wei Wu, Shih-Ho Wang +3 more
2023Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie28 citations Open access
Semantic Scholar
Low-Energy Extracorporeal Shock Wave Therapy Ameliorates Kidney Function in Diabetic Nephropathy
Chang-Chun Hsiao, Wei-Han Huang, Kuang-Hung Cheng, Chien-Te Lee
2019Oxidative Medicine and Cellular Longevity28 citations Open access
Semantic Scholar
Long-Term Use of Probiotic-Containing Yogurts Is a Safe Way to Prevent Helicobacter pylori: Based on a Mongolian Gerbil's Model
Chao-Hung Kuo, Sophie S. W. Wang, Chien-Yu Lu, Huang-Ming Hu +10 more
2013Biochemistry Research International28 citations Open access
Semantic Scholar
Deciphering The Potential Role of Hox Genes in Pancreatic Cancer
Tzu-Lei Kuo, Kuang-Hung Cheng, Li-Tzong Chen, W. Hung
2019Cancers27 citations Open access
Semantic Scholar
Pancreatic Tumor Progression Associated With CD133 Overexpression: Involvement of Increased TERT Expression and Epidermal Growth Factor Receptor–Dependent Akt Activation
Ching-Chieh Weng, K. Kuo, Huei-Ting Su, Pi-Jung Hsiao +4 more
2016Pancreas24 citations
Semantic Scholar
Semiconductor Nanomaterials-Based Fluorescence Spectroscopic and Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometric Approaches to Proteome Analysis
S. K. Kailasa, Kuang-Hung Cheng, Hui-Fen Wu
2013Materials24 citations Open access
Semantic Scholar
MAL-PDT inhibits oral precancerous cells and lesions via autophagic cell death.
Yen-Yun Wang, Yuk-Kwan Chen, Chunxia Hu, Ling-Yi Xiao +5 more
2019Oral Diseases22 citations
Semantic Scholar
Effects of Antidepressants on IP-10 Production in LPS-Activated THP-1 Human Monocytes
J. Tsai, Chang-Hung Kuo, Pin-Chen Yang, Kuang-Hung Cheng +3 more
2014International Journal of Molecular Sciences22 citations Open access
Semantic Scholar
Suppression of IL‐8‐Src signalling axis by 17β‐estradiol inhibits human mesenchymal stem cells‐mediated gastric cancer invasion
Chung-Jung Liu, Fu-Chen Kuo, Chiu-Lin Wang, Chao-Hung Kuo +8 more
2016Journal of Cellular and Molecular Medicine21 citations Open access
Semantic Scholar
Fast detection of tumor marker CA 19-9 using AlGaN/GaN high electron mobility transistors
Ching-Wen Chang, Pei-Run Chen, Shenghai Wang, Shi-Ya Hsu +10 more
2018Sensors and actuators. B, Chemical19 citations
Semantic Scholar
17β-Estradiol inhibition of IL-6-Src and Cas and paxillin pathway suppresses human mesenchymal stem cells-mediated gastric cancer cell motility.
Chung-Jung Liu, Fu-Chen Kuo, Huang-Ming Hu, Chiao-Yun Chen +6 more
2014Translational Research: The Journal of Laboratory and Clinical Medicine19 citations
Semantic Scholar
Quantitative Proteomic Analysis of Differentially Expressed Protein Profiles Involved in Pancreatic Ductal Adenocarcinoma
K. Kuo, Chao-Jen Kuo, Chiang-Yen Chiu, Shih-Shin Liang +7 more
2015Pancreas17 citations Open access
Semantic Scholar
Utilization of Liquid Chromatography Mass Spectrometry Analyses to Identify LKB1–APC Interaction in Modulating Wnt/β-Catenin Pathway of Lung Cancer Cells
Shu‐Fang Jian, Chang-Chun Hsiao, Shin-Yi Chen, Ching-Chieh Weng +4 more
2014Molecular Cancer Research15 citations
Semantic Scholar
ARID1A loss in pancreas leads to islet developmental defect and metabolic disturbance
Tzu-Lei Kuo, Kuang-Hung Cheng, Li-Tzong Chen, W. Hung
2022iScience14 citations Open access
Semantic Scholar
Inactivation of APC Induces CD34 Upregulation to Promote Epithelial-Mesenchymal Transition and Cancer Stem Cell Traits in Pancreatic Cancer
Mei-Jen Hsieh, Tai-Jan Chiu, Yu-Chun Lin, Ching-Chieh Weng +3 more
2020International Journal of Molecular Sciences14 citations Open access
Semantic Scholar
hBub1 deficiency triggers a novel p53 mediated early apoptotic checkpoint pathway in mitotic spindle damaged cells
Fangming Gao, Jose F. Ponte, Mary Levy, P. Papageorgis +8 more
2009Cancer Biology & Therapy14 citations Open access
Semantic Scholar
Jdp2 is a spatiotemporal transcriptional activator of the AhR via the Nrf2 gene battery
Kenly Wuputra, Ming‐Ho Tsai, Kohsuke Kato, C. Ku +13 more
2023Inflammation and Regeneration12 citations Open access
Semantic Scholar
Fumarate hydratase inhibits non-small cell lung cancer metastasis via inactivation of AMPK and upregulation of DAB2
Anupama Vadhan, Yi-Fang Yang, Yun-Ming Wang, Pang-Yu Chen +6 more
2022Oncology Letters11 citations Open access
Semantic Scholar
Probing the Adhesion of Hepatocellular Carcinoma HepG2 and SK-Hep-1 Cells
S. Hsieh, P. Lin, Chiung-wen Hsieh, I-Tin Li +8 more
201211 citations
Semantic Scholar
The Use of Genetically Engineered Mouse Models for Studying the Function of Mutated Driver Genes in Pancreatic Cancer
Ching-Chieh Weng, Yu-Chun Lin, Kuang-Hung Cheng
2019Journal of Clinical Medicine9 citations Open access
Semantic Scholar
Association between GABA(A) receptor subunit gene cluster and zolpidem-induced complex sleep behaviors in Han Chinese.
J. Tsai, Pin-Chen Yang, Hung-Hsun Lin, Kuang-Hung Cheng +3 more
2013Sleep8 citations Open access
Semantic Scholar
Inhibition of β-Catenin Activity Abolishes LKB1 Loss-Driven Pancreatic Cystadenoma in Mice
Mei-Jen Hsieh, Ching-Chieh Weng, Yu-Chun Lin, Chia-Chen Wu +2 more
2021International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
KRAS K104 modification affects the KRASG12D-GEF interaction and mediates cell growth and motility
Chih-Chieh Chen, Chia-Yi Hsu, Hsiao-Yun Lin, Hong Zeng +4 more
2020Scientific Reports6 citations Open access
Semantic Scholar

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