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E. Rayner · SciRah

Researcher profile · Semantic Scholar

E. Rayner

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E. Rayner — researcher profile on SciRah

h-index: 29
Works: 68
Citations: 2,511

Most-cited papers

A Susceptible Mouse Model for Zika Virus Infection
S. Dowall, Victoria A. Graham, E. Rayner, B. Atkinson +6 more
2016bioRxiv300 citations Open access
Semantic Scholar
Comparison of rhesus and cynomolgus macaques as an infection model for COVID-19
F. J. Salguero, A. White, G. Slack, S. Fotheringham +60 more
2021Nature Communications153 citations Open access
Semantic Scholar
Dose-dependent response to infection with SARS-CoV-2 in the ferret model and evidence of protective immunity
K. Ryan, K. Bewley, S. Fotheringham, G. Slack +51 more
2021Nature Communications149 citations Open access
Semantic Scholar
Alternative BCG delivery strategies improve protection against Mycobacterium tuberculosis in non-human primates: Protection associated with mycobacterial antigen-specific CD4 effector memory T-cell populations
S. Sharpe, A. White, C. Sarfas, L. Sibley +9 more
2016Tuberculosis134 citations Open access
Semantic Scholar
A Novel Vaccine against Crimean-Congo Haemorrhagic Fever Protects 100% of Animals against Lethal Challenge in a Mouse Model
Karen Buttigieg, S. Dowall, S. Findlay-Wilson, Aleksandra Miloszewska +3 more
2014PLoS ONE134 citations Open access
Semantic Scholar
Chloroquine inhibited Ebola virus replication in vitro but failed to protect against infection and disease in the in vivo guinea pig model.
S. Dowall, Andrew Bosworth, Robert J. Watson, K. Bewley +8 more
2015Journal of General Virology116 citations Open access
Semantic Scholar
A Crimean-Congo hemorrhagic fever (CCHF) viral vaccine expressing nucleoprotein is immunogenic but fails to confer protection against lethal disease
S. Dowall, Karen Buttigieg, S. Findlay-Wilson, E. Rayner +5 more
2015Human Vaccines & Immunotherapeutics95 citations Open access
Semantic Scholar
Prophylactic intranasal administration of a TLR2/6 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model
P. Proud, D. Tsitoura, Robert J. Watson, B. Chua +22 more
2020EBioMedicine88 citations Open access
Semantic Scholar
Hazara virus infection is lethal for adult type I interferon receptor-knockout mice and may act as a surrogate for infection with the human-pathogenic Crimean-Congo hemorrhagic fever virus.
S. Dowall, S. Findlay-Wilson, E. Rayner, G. Pearson +6 more
2012Journal of General Virology74 citations Open access
Semantic Scholar
Therapeutic Monoclonal Antibodies for Ebola Virus Infection Derived from Vaccinated Humans.
Pramila Rijal, S. Elias, Samara Rosendo Machado, J. Xiao +24 more
2019Cell Reports73 citations Open access
Semantic Scholar
Non-Replicating Mycobacterium tuberculosis Elicits a Reduced Infectivity Profile with Corresponding Modifications to the Cell Wall and Extracellular Matrix
Joanna Bacon, L. Alderwick, J. A. Allnutt, Evelina Gabasova +13 more
2014PLoS ONE72 citations Open access
Semantic Scholar
Ultra low dose aerosol challenge with Mycobacterium tuberculosis leads to divergent outcomes in rhesus and cynomolgus macaques.
S. Sharpe, A. White, F. Gleeson, A. Mcintyre +8 more
2016Tuberculosis65 citations Open access
Semantic Scholar
Lineage-dependent differences in the disease progression of Zika virus infection in type-I interferon receptor knockout (A129) mice
S. Dowall, Victoria A. Graham, E. Rayner, L. Hunter +4 more
2017PLoS Neglected Tropical Diseases60 citations Open access
Semantic Scholar
Protective effects of a Modified Vaccinia Ankara-based vaccine candidate against Crimean-Congo Haemorrhagic Fever virus require both cellular and humoral responses
S. Dowall, Victoria A. Graham, E. Rayner, L. Hunter +5 more
2016PLoS ONE60 citations Open access
Semantic Scholar
Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system.
D. Bottai, Wafa Frigui, Simon O. Clark, E. Rayner +7 more
2015Vaccine56 citations Open access
Semantic Scholar
mRNA vaccine CVnCoV protects non-human primates from SARS-CoV-2 challenge infection
S. Rauch, K. Gooch, Y. Hall, F. Salguero +15 more
2020bioRxiv52 citations Open access
Semantic Scholar
Low Dose Influenza Virus Challenge in the Ferret Leads to Increased Virus Shedding and Greater Sensitivity to Oseltamivir
A. Marriott, B. Dove, Catherine J Whittaker, Christine B. Bruce +14 more
2014PLoS ONE52 citations Open access
Semantic Scholar
Deletion of zmp1 improves Mycobacterium bovis BCG-mediated protection in a guinea pig model of tuberculosis.
P. Sander, Simon O. Clark, Agnese Petrera, C. Vilaplana +12 more
2015Vaccine51 citations
Semantic Scholar
Protective efficacy of a lipid antigen vaccine in a guinea pig model of tuberculosis.
G. Larrouy-Maumus, É. Layre, Simon O. Clark, J. Prandi +6 more
2017Vaccine48 citations
Semantic Scholar
MTBVAC vaccination protects rhesus macaques against aerosol challenge with M. tuberculosis and induces immune signatures analogous to those observed in clinical studies
Andrew D. White, L. Sibley, C. Sarfas, Alexandra L. Morrison +15 more
2021npj Vaccines47 citations Open access
Semantic Scholar
Dose-dependent response to infection with SARS-CoV-2 in the ferret model: evidence of protection to re-challenge
K. Ryan, K. Bewley, S. Fotheringham, Phillip J. Brown +45 more
2020bioRxiv45 citations Open access
Semantic Scholar
Revaccination of Guinea Pigs With the Live Attenuated Mycobacterium tuberculosis Vaccine MTBVAC Improves BCG's Protection Against Tuberculosis
Simon O. Clark, Faye Lanni, D. Marinova, E. Rayner +2 more
2017Journal of Infectious Diseases38 citations
Semantic Scholar
Sequence of Pathogenic Events in Cynomolgus Macaques Infected with Aerosolized Monkeypox Virus
J. Tree, Graham Hall, G. Pearson, E. Rayner +9 more
2015Journal of Virology38 citations Open access
Semantic Scholar
Efficacy of Liposome-Encapsulated Ciprofloxacin in a Murine Model of Q Fever
I. Norville, G. Hatch, K. Bewley, D. J. Atkinson +8 more
2014Antimicrobial Agents and Chemotherapy33 citations Open access
Semantic Scholar
Abdominal fibrosarcoma associated with a retained surgical swab in a dog.
E. Rayner, C. L. Scudamore, I. Francis, S. Schöniger
2010Journal of Comparative Pathology32 citations Open access
Semantic Scholar
Protective Efficacy of Inhaled BCG Vaccination Against Ultra-Low Dose Aerosol M. tuberculosis Challenge in Rhesus Macaques
A. White, C. Sarfas, L. Sibley, Jennie Gullick +10 more
2020Pharmaceutics31 citations Open access
Semantic Scholar
Adenoviral vectored vaccination protects against Crimean-Congo Haemorrhagic Fever disease in a lethal challenge model
J. Saunders, Ciaran Gilbride, S. Dowall, Susan J. Morris +10 more
2023EBioMedicine29 citations Open access
Semantic Scholar
Immunological and pathological outcomes of SARS-CoV-2 challenge following formalin-inactivated vaccine in ferrets and rhesus macaques
K. Bewley, K. Gooch, Kelly M. Thomas, S. Longet +38 more
2021Science Advances29 citations Open access
Semantic Scholar
Route of delivery to the airway influences the distribution of pulmonary disease but not the outcome of Mycobacterium tuberculosis infection in rhesus macaques.
L. Sibley, M. Dennis, C. Sarfas, A. White +8 more
2016Tuberculosis29 citations Open access
Semantic Scholar
Development of a Cost-effective Ovine Polyclonal Antibody-Based Product, EBOTAb, to Treat Ebola Virus Infection
S. Dowall, J. Callan, A. Zeltiña, Ibrahim Al-Abdulla +13 more
2015Journal of Infectious Diseases29 citations Open access
Semantic Scholar
Influence of Aerosol Delivered BCG Vaccination on Immunological and Disease Parameters Following SARS-CoV-2 Challenge in Rhesus Macaques
A. White, L. Sibley, C. Sarfas, Alexandra L. Morrison +25 more
2022Frontiers in Immunology26 citations Open access
Semantic Scholar
Early lesions following aerosol infection of rhesus macaques (Macaca mulatta) with Mycobacterium tuberculosis strain H37RV.
E. Rayner, G. Pearson, Graham Hall, R. Basaraba +6 more
2013Journal of Comparative Pathology26 citations
Semantic Scholar
Comparative pathology of experimental pulmonary tuberculosis in animal models
Laura Hunter, Inés Ruedas-Torres, I. Agulló-Ros, E. Rayner +1 more
2023Frontiers in Veterinary Science21 citations Open access
Semantic Scholar
TNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers
P. Morton, A. Hicks, Elena Ortiz-Zapater, S. Raghavan +7 more
2016Scientific Reports21 citations Open access
Semantic Scholar
Immunogenicity and Efficacy of Zika Virus Envelope Domain III in DNA, Protein, and ChAdOx1 Adenoviral-Vectored Vaccines
C. López-Camacho, G. De Lorenzo, J. Slon-Campos, S. Dowall +17 more
2020Vaccines20 citations Open access
Semantic Scholar
One or two dose regimen of the SARS-CoV-2 synthetic DNA vaccine INO-4800 protects against respiratory tract disease burden in nonhuman primate challenge model
K. Gooch, Trevor R. F. Smith, F. Salguero, S. Fotheringham +21 more
2021Vaccine19 citations Open access
Semantic Scholar
Evaluation of the Efficacy of Doxycycline, Ciprofloxacin, Levofloxacin, and Co-trimoxazole Using In Vitro and In Vivo Models of Q Fever
K. Clay, M. G. Hartley, S. Armstrong, K. Bewley +6 more
2021Antimicrobial Agents and Chemotherapy16 citations Open access
Semantic Scholar
Sequential delivery of LAIV and SARS-CoV-2 in the ferret model can reduce SARS-CoV-2 shedding and does not result in enhanced lung pathology
K. Ryan, K. Schewe, Jonathan Crowe, S. Fotheringham +10 more
2021bioRxiv16 citations Open access
Semantic Scholar
Early lesions following aerosol challenge of rhesus macaques (Macaca mulatta) with Mycobacterium tuberculosis (Erdman strain).
E. Rayner, G. Pearson, G. Hall, Fergus Gleeson +4 more
2015Journal of Comparative Pathology13 citations
Semantic Scholar
Post-exposure treatment of Ebola virus disease in guinea pigs using EBOTAb, an ovine antibody-based therapeutic
S. Dowall, Andrew Bosworth, E. Rayner, Irene Taylor +9 more
2016Scientific Reports12 citations Open access
Semantic Scholar
Characterisation and development of histopathological lesions in a guinea pig model of Mycobacterium tuberculosis infection
F. Larenas-Muñoz, Inés Ruedas-Torres, Laura Hunter, Alison Bird +5 more
2023Frontiers in Veterinary Science11 citations Open access
Semantic Scholar
Post-exposure treatment of non-human primates lethally infected with Ebola virus with EBOTAb, a purified ovine IgG product
S. Dowall, Frédéric Jacquot, J. Landon, E. Rayner +9 more
2017Scientific Reports11 citations Open access
Semantic Scholar
Syrian hamster convalescence from prototype SARS-CoV-2 confers measurable protection against the attenuated disease caused by the Omicron variant
K. Ryan, K. Bewley, Robert J. Watson, Christopher Burton +37 more
2023PLoS Pathogens10 citations Open access
Semantic Scholar
Comparison of Chikungunya Virus-Induced Disease Progression and Pathogenesis in Type-I Interferon Receptor-Deficient Mice (A129) and Two Wild-Type (129Sv/Ev and C57BL/6) Mouse Strains
Victoria A. Graham, L. Easterbrook, E. Rayner, S. Findlay-Wilson +6 more
2024Viruses9 citations Open access
Semantic Scholar
Spore-FP1 tuberculosis mucosal vaccine candidate is highly protective in guinea pigs but fails to improve on BCG-conferred protection in non-human primates
A. White, A. Tran, L. Sibley, C. Sarfas +22 more
2023Frontiers in Immunology9 citations Open access
Semantic Scholar
Finafloxacin, a Novel Fluoroquinolone, Reduces the Clinical Signs of Infection and Pathology in a Mouse Model of Q Fever
M. G. Hartley, I. Norville, M. Richards, Kay B. Barnes +6 more
2021Frontiers in Microbiology8 citations Open access
Semantic Scholar
A Multi-Valent Hantavirus Vaccine Based on Recombinant Modified Vaccinia Ankara Reduces Viral Load in a Mouse Infection Model
Marilyn Aram, Victoria A. Graham, E. Kennedy, E. Rayner +2 more
2025Vaccines7 citations Open access
Semantic Scholar
Comparison of Rhesus and Cynomolgus macaques as an authentic model for COVID-19
F. Salguero, A. White, G. Slack, S. Fotheringham +54 more
2020bioRxiv7 citations Open access
Semantic Scholar
Parenteral Administration of Capsule Depolymerase EnvD Prevents Lethal Inhalation Anthrax Infection
D. Negus, J. Vipond, G. Hatch, E. Rayner +1 more
2015Antimicrobial Agents and Chemotherapy7 citations Open access
Semantic Scholar
DNA-Vaccine-Induced Immune Response Correlates with Lower Viral SARS-CoV-2 Titers in a Ferret Model
M. Compagnone, Eleonora Pinto, E. Salvatori, L. Lione +12 more
2022Vaccines5 citations Open access
Semantic Scholar

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